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All Journal Medula Juke Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Journal Syifa Sciences and Clinical Research (JSSCR) JK Unila (Jurnal Kedokteran Universitas Lampung) Indonesian Community Empowerment Journal Jurnal Pengabdian Masyarakat JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Muhammad Ricky Ramadhian
Fakultas Kedokteran, Universitas Lampung
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Medula

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Enterobactericeae Sebagai Bakteri Patogen Infeksi Nosokomial di Rumah Sakit Putri, Abrila Tamara; Soleha, Tri Umiana; Nareswari, Shinta; Ramadhian, M. Ricky
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.942

Abstract

Enterobactericeae are gram-negative rod bacteria which are often pathogenic bacteria that cause nosocomial infections. Enterobactericeae bacteria have several characteristics including small size and rod shape, natural habitat in the digestive tract of humans or animals and some others originate from bodies or inanimate objects, are motile and non-motile, cannot form spores, and are aerobic to facultative anaerobic. Nosocomial infections are infections that are acquired during the health care process at the hospital, but are not present when the patient is admitted to the hospital. The source of transmission of nosocomial infections can result from direct or indirect contamination in the health care process in hospitals. Common nosocomial infections include Central Line Associated Blood Stream Infection (CLABSI), Catheter Associated Urinary Tract Infection (CAUTI), Surgical Site Infection (SSI), and nosocomial pneumonia consisting of Hospital Acquired Pneumoniae (HAP), Ventilator Associated Pneumoniae (VAP), and Health Care Associated Pneumoniae (HCAP). The Enterobactericeae bacteria that often cause nosocomial infections in hospitals include Escherichia coli, Klebsiella sp, Enterobacter sp, Pseudomonas sp, and so on. Nosocomial infections have a negative impact on the health recovery process of inpatients in hospital, so they need to be handled well and preventive efforts are made to avoid this undesirable event through health service efforts that comply with standard operational procedures and pay attention to aseptic principles.
Deteksi Dini dan Tatalaksana Rheumatoid Arthritis Farhry Alvini Rahmania; Sibero, Hendra Tarigan; Ramadhian, Muhammad Ricky
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.967

Abstract

Rheumatoid arthritis (RA) is a long-term progressive inflammatory autoimmune disorder that can caused damage to the joints into disability, if it isn’t handled appropriately. There are 1.4 million people in Indonesia that have been found to suffer from rheumatoid arthritis. In the early stages of rheumatoid arthritis, there are symptoms such as fatigue, flu-like syndromes, swollen joints and pain, and morning stiffness; and also increased levels of C-reactive protein (CRP) and increased sedimentation rate of erythorisite (ESR). In contrast, untreated rheumatoid arthritis displays severe systemic manifestations such as pleural effusion, pulmonary nodules and interstitial lung disease, IMF, vasculitis in small and medium arteries, re-evolution, cartilage damage, rheumatic nodules and others. Diagnosis of rheumatoid arthritis is established after assessing symptoms, physical examination, risk factor, family history, assessment along with ultrasound, and lab marker assessment such as increased levels of CRP and ESR in serum and detection of RA-specific autoantibodies. Rheumatoid arthritis is incurable, but it can be controlled with appropriate medication and prognosis monitoring. The prognosis of rheumatoid arthritis is based on clinical evidence and laboratory examination. Early detection and appropriate management of rheumatoid arthritis are key to better prognosis. This article therefore discusses the importance of early diagnosis and treatment of rheumatoid arthritis.
Literature Review : Antibacterial Activity of Various Mangrove Plant Species Extracts Balqis, Aurelia Corrinna; Kurniawaty, Evi; Maulana, Muhammad; Ramadhian, Muhammad Ricky
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1322

Abstract

The excessive and uncontrolled use of antibiotics has led to antibiotic resistance in pathogenic bacteria, which poses a serious threat to global health. To address this problem, alternative treatments from natural materials, such as mangrove plants, are starting to attract attention. Mangrove plants contain bioactive compounds that have antibacterial potential against various pathogenic bacteria. This study aims to review the antibacterial activity of various mangrove species in Indonesia. The method used was a literature study that included analysis of recent journals on the antibacterial activity of mangrove plants. The results showed that extracts from various mangrove species, such as Bruguiera gymnorrhiza, Rhizophora mucronata, and Heritiera littoralis, had significant antibacterial activity against Gram-positive and Gram-negative bacteria, such as Escherichia coli, Staphylococcus aureus, and Salmonella enterica. The zones of inhibition produced varied between 5 to 20 mm, with the ethanol extract from Bruguiera gymnorrhiza leaves showing the most potent activity. In addition, the assay results showed that the active compounds in the mangrove extracts had the ability to inhibit bacterial growth at low concentrations, indicating great potential for the development of more efficient and economical antibacterial drugs. This study provides evidence that mangrove plant extracts have potential as antibacterial agents that can be further developed for the treatment of infections caused by pathogenic bacteria, thus providing an effective alternative to overcome the problem of antibiotic resistance.
Analisis Klinis Dispepsia pada Pasien Kolelitiasis: Studi Literatur Gultom, Dea Debora Romauli; Ramadhian, Muhammad Ricky; Lusina, Septia Eva; Darwis, Iswandi
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1377

Abstract

Cholelithiasis, also known as gallstones, is a health problem that has been increasing in prevalence worldwide. Some patients with cholelithiasis experience dyspepsia, a condition that causes discomfort in the upper digestive tract. This study aims to analyze the clinical relationship between cholelithiasis and dyspepsia based on a literature review. The articles used in this study were collected from scientific sources such as PubMed, Google Scholar, and Science Direct. A descriptive analysis was conducted to identify the prevalence, risk factors, and mechanisms linking cholelithiasis with dyspepsia. The results show that most patients with cholelithiasis and dyspepsia are female. The most frequently reported symptoms are abdominal pain (100%), nausea (69%), and vomiting (27%). Eating fatty foods can make these symptoms worse. While many patients feel better after having cholecystectomy, about 30% still experience dyspepsia even after surgery. This connection may be due to issues with gastrointestinal motility disorders, bile reflux, and other multifactorial causes. However, the relationship between cholelithiasis and dyspepsia remains a subject of debate, requiring further research to uncover its mechanisms and develop more effective diagnostic and therapeutic strategies.
Peran Resiliensi dalam Mengurangi Stres Mahasiswa Kepaniteraan Klinik: Tinjauan Pustaka Syafira Salsabila; Lisiswanti, Rika; Yuningrum, Hesti; Ramadhian, Muhammad Ricky
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1417

Abstract

The transition from the preclinical to the clinical phase of medical education, characterized by a significant difference in the learning system and increased demands, often leads to stress among medical students. A very packed schedule, tight deadlines, and the need to adapt to a dynamic clinical environment are primary stressors for medical students during their clerkship. Prolonged high levels of stress can negatively impact mental health, academic performance, and the quality of medical care, increasing the risk of medical malpractice. Resilience, defined as an individual's ability to recover from difficult situations, has proven to be a crucial protective factor in mitigating the effects of stress. Resilience is a dynamic process demonstrated when individuals take adaptive actions in the face of adversity. It is not a genetic trait but a behavior that can be developed by strengthening the factors that support it. These factors can be internal, external, or interpersonal. One way to enhance resilience is through resilience training programs that involve interactive, independent, and reflective workshops. High levels of resilience among medical students are associated with increased subjective well-being, reduced stress levels, and a more positive perception of quality of life and the educational environment. Therefore, by enhancing resilience, medical students can better cope with the pressures of clerkship, maintain mental health, and optimize academic performance in medical care.
Pemeriksaan Ultrasonografi Elastografi dalam Diagnosis Penyakit Ginjal Adisti, Fransiska; Ramadhian, Muhammad Ricky; Maulana, Muhammad; Berawi, Khairun Nisa
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1299

Abstract

Ultrasonography (USG) is a diagnostic tool in medical imaging that operates on the principle of ultrasound waves emitted by a transducer. Recent advancements in USG technology have significantly enhanced its diagnostic capabilities. Renal elastography, a specialized application, enables the assessment of tissue stiffness or elasticity. The technique involves applying pressure to the tissue and measuring the resulting strain, providing valuable insights into the extent of fibrosis in the renal parenchyma. This article presents a comprehensive review of renal elastography ultrasonography and its clinical applications. USG is a non-invasive imaging modality that requires no special preparation, typically performed with the patient in a supine position. The kidneys are evaluated in longitudinal and transverse planes using a transducer positioned at the flank. Various elastography techniques exist, categorized based on the intensity of external pressure applied.
Peran Anemia Sebagai Faktor Risiko Hipertensi Resisten pada Penyakit Ginjal Kronik Nasution, Salwa Salsabila; Kurniati, Intanri; Ratna, Maya Ganda; Ramadhian, M. Ricky
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1354

Abstract

Anemia is one of the most common complications in chronic kidney disease (CKD) that significantly affects quality of life and prognosis. Anemia is a condition where there is a decrease in iron-rich hemoglobin levels, which functions to circulate oxygen throughout the body. Chronic kidney disease is a kidney condition characterized by abnormalities in kidney structure or function. Men have a 2 times higher risk of developing CKD than women due to their generally poorer lifestyle habits. The condition of insufficient oxygen perfusion to tissues leads to activation of the renin-angiotensin-aldosterone system (RAAS). The RAAS system ultimately produces aldosterone and antidiuretic hormones that cause sodium retention in the body and lead to increased blood pressure. Additionally, anemia can cause changes in blood vessels, where there is an increase in vascular resistance, especially in CKD patients. Studies have also shown that erythropoietin therapy can increase the prevalence of hypertension. Resistant hypertension is a condition where someone suffering from hypertension fails to achieve target blood pressure of <140/80 mmHg in normal individuals and <130/80 mmHg in CKD patients despite adhering to a combination dose of three types of antihypertensive medications. Someone suffering from resistant hypertension must comply with the drug dosage prescribed by the doctor and also improve their lifestyle. This article aims to understand how anemia serves as a risk factor for resistant hypertension in CKD patients. Furthermore, the diagnosis and treatment of resistant hypertension are also discussed in this article.
Demensia Alzheimer pada Lansia Nadhifa, Farin; Ramadhian, Muhammad Ricky; Nareswari, Shinta
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1355

Abstract

Alzheimer’s dementia in the elderly is a health problem that affects the quality of life of patients and their families. This study aims to explore the risk factors, prevention, and management of Alzheimer's Dementia in the elderly, focusing on the use of information technology for early detection, and the impact of physical activity as a preventive strategy. This research utilizes a literature review method by analyzing previous studies related to Alzheimer's dementia in the elderly. The analysis includes risk factors for dementia, prevention through physical activity, and the role of information technology in early detection and disease management. The results of the literature review indicate that the risk factors for Alzheimer's dementia in the elderly include age, genetics, and lifestyle. The study also shows that physical activity has a positive effect in reducing the risk of dementia. Moreover, information technology has significant potential in aiding early detection and disease management, allowing for more timely and effective intervention. Alzheimer’s dementia in the elderly requires a comprehensive approach involving early detection, prevention, and disease management. Physical activity and the use of information technology play vital roles in preventive and therapeutic strategies for Alzheimer's dementia.
Karakteristik Pasien Apendisitis di RSUD Dr. H. Abdul Moeloek Fitria, Aghniya Rizqy; Ricky Ramadhian, Muhammad; Daulay, Suryani Agustina; Zuraida, Reni
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1405

Abstract

Appendicitis is inflammation of the vermiform appendix that can lead to perforation if not treated promptly. This study aims to identify the characteristics of appendicitis patients at RSUD Dr. H. Abdul Moeloek Lampung Province from January 2023 to July 2024. The method used was a descriptive observational study using secondary data from medical records of appendicitis patients. The sample was taken using total sampling, which was then selected based on inclusion and exclusion criteria, involving 84 patients with complete medical records and histopathology results. The results showed that the majority of appendicitis patients were in the 21-60 age range (49%), followed by the 0-20 age range (44%) and the >60 age group (7%). Based on gender, more male patients (56%) were found compared to females (44%). The most common type of appendicitis was simple acute appendicitis (48.8%), followed by perforated acute appendicitis (36.9%) and chronic appendicitis (14.3%). These findings are consistent with other studies showing a higher incidence of appendicitis in young adults and a higher prevalence in males. This study provides important insights into the characteristics of appendicitis patients, which may aid in early detection and more effective management.
Cystatin C sebagai Biomarker Fungsi Ginjal: Literature Review Pestalozi, George; Akbar, Fareel Wahyu; Ramadhian, Muhammad Ricky; Graharti, Risti; Lisiswanti, Rika
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1410

Abstract

Kidneys are the primary organs responsible for the excretion of metabolic waste products. Glomerular Filtration Rate (GFR) serves as a critical parameter for assessing renal function, with serum creatinine traditionally utilized as the primary biomarker. However, the accuracy of creatinine-based assessments is limited by its susceptibility to external variables, including age, sex, muscle mass, and dietary intake. These factors can lead to variability in results and reduce diagnostic precision. To overcome these limitations, cystatin C (CysC) has gained prominence as a superior alternative biomarker. Unlike creatinine, serum CysC levels are minimally influenced by external factors, offering greater stability and sensitivity in detecting acute kidney injury (AKI), chronic kidney disease (CKD), and other renal impairments such as diabetic nephropathy. Cystatin C provides notable advantages in the reclassification of CKD stages, particularly in cases where GFR measurements are borderline. CysC has demonstrated superior reliability over creatinine in predicting complications such as delayed graft function (DGF), a condition often necessitating hemodialysis. Preoperative measurement of CysC levels is instrumental in predicting long-term renal function and identifying patients at elevated risk for adverse outcomes. Elevated serum CysC concentrations in patients with renal cell carcinoma (RCC) have been correlated with poorer prognoses and an increased likelihood of postoperative renal injury. Despite its clinical advantages, the routine adoption of CysC is constrained by certain limitations. Chief among these is the significantly higher cost of CysC assays compared to traditional creatinine tests, which restricts its widespread application to confirmatory diagnostics or complex clinical scenarios.
Co-Authors Ade Marantika Adisti, Fransiska Afriyani, Afriyani Akbar, Fareel Wahyu Anggraini, Dian Isti Aprina Adha Widiastini Asep Sukohar Atika Threenesia Balqis, Aurelia Corrinna Benny Bradley Pradana Pangaribuan Betta Kurniawan, Betta Daulay, Suryani Agustina Delvi Rusitaini Putri Diana Mayasari Efrida Warganegara Ekki Pirmansyah Ermin Rachmawati Ety Apriliana Ety Apriliana Falamy, Ryan Farhry Alvini Rahmania Fitria, Aghniya Rizqy George Pestalozi Gultom, Dea Debora Romauli Hanna Mutiara, Hanna Hendra Tarigan Sibero Intanri Kurniati Iswandi Darwis Jhons Fatriyadi Suwandi Khairil Pahmi Khairil Pahmi Khairun Nisa Kurniawaty, Evi Lusina, Septia Eva M Sidratullah Marcellia, Selvi Meta Gapila Muhammad Maulana Muhammad Taupik Nadhifa, Farin Nasution, Salwa Salsabila Nora Ramkita Novita Carolia Nurul Sahana Rahmadhini Nurul Utami Oktadoni Saputra, Oktadoni Putri, Abrila Tamara Ratna, Maya Ganda Reni Zuraida Rifda Khairunnisa Rika Lisiswanti Risti Graharti Septiani, Linda Shinta Nareswari, Shinta Suryadi Islami Sutarto Sutarto Syafira Salsabila Syazili Mustofa Tri Umiana Sholeha Tri Umiana Soleha Tri Umiana Soleha Yuniarti, Wulan Yuningrum, Hesti