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All Journal Alchemy : Journal of Chemistry Indonesian Journal of Cancer Chemoprevention Indonesian Journal of Tropical and Infectious Disease Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Journal of Islamic Pharmacy JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Majalah Obstetri dan Ginekologi SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Masyarakat Asia Humanism : Jurnal Pengabdian Masyarakat Jurnal Kreativitas dan Inovasi (Jurnal Kreanova) Jurnal Masyarakat Madani Indonesia Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Widya Medika
Aty Widyawaruyanti
Departemen Ilmu Kefarmasian Fakultas Farmasi Universitas Airlangga, Surabaya
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Ilmu Kefarmasian Indonesia

 1 
Aktivitas Antimalaria Ekstrak Kulit Batang Cempaka Kuning Terhadap Plasmodium Falciparum 3D7 NI PUTU ARIANTARI; NI LUH RUSTINI; LIDYA TUMEWU; ACHMAD FUAD HAFID; ATY WIDYAWARUYANTI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 11 No 1 (2013): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Cempaka kuning (Michelia champaca) which is belongs to Magnoliaceae family, has been traditionally used for treatment fever. This research was conducted to evaluate antimalarial activity of Cempaka kuning stembark extract against Plasmodium falciparum 3D7 in vitro. Cempaka kuning stembark was extracted with n-hexane, chloroform and methanol yielded n-hexane extract, chloroform extract and methanol extract, followed by antimalarial activity assay of these extracts. Phytochemical screening showed that n-hexane extract contain volatile oil and terpenoids, chloroform extract contain Volatile oil, terpenoids and fiavonoids, then methanol extract contain volatile oil, terpenoids, flavonoids, tannins and glycosides. Result of this study also showed that n-hexane extract, chloroform extract and methanol extract were active against P. alciparum 3D7 in vitro, with an IC50 value of 0.36, 0.24 and 1.00 µg/mL. The findings indicate that Cempaka kuning stembark extracts possess strong antimalarial activity and are prospective to be developed as antimalarial.
Efek Pemberian Dosis Berulang dan Dosis Tunggal Ekstrak Kulit Batang Cempedak (Artocarpus Champeden Spreng.) Pada Mencit Terinfeksi Plasmodium Berghei SOFIANA SARI; ACHMAD FUAD HAFID; ATY WIDYAWARUYANTI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 13 No 1 (2015): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Artocarpus champeden Spreng. (Moraceae) known as “cempedak”, was traditionally used for antimalarial remedies in Indonesia. Study to determine antimalarial activity of ethanol extract of cempedak stembark was carried out. Artocarpus champeden Ethanol Extract (ACEE) was administered twice per day (multiple dose) and once per day (single dose) orally. The study was carried out by modification method of the “4 Days Suppressive Test” originally described by Peter. The result showed that ACEE administered twice per day inhibited parasites growth (ED 0.19 mg/kg BW) higher than once per day (ED 6.0 mg/kg BW) and 10 mg/kg body weight of dose administrated twice per day was more effective than 100 mg/kg body weight once per day.
Co-Authors Abdul Rahman Achmad Fuad Achmad Fuad Hafid Achmad Toto Poernomo Achmad Yunus Adita Ayu Permanasari, Adita Ayu Adita Ayu Permatasari AGUS HARIANTO Agus Pratiwi Andang Miatmoko Budi Prasetyo Chie Aoki-Utsubo Corry, Maylisa Natalia Dahri, Baso Desak Ketut Ayu Aryani Devanus Lahardo Diyah, Nuzul Wahyuning Djoko Agus Purwanto Edhi, Narendrani Sasmitaning Einstenia Kemalahayati Erry Gumilar Dachlan, Esti Hendradi Firmansyah Ardian Ramadhani Hadi Kuncoro Hadi Poerwono Handayani, Rosita Hanifah Khairun Nisa Hasan, Muhammad Amir Hidayati, Agriana Rosmalina Hidayatus, Laila Nur Hilkatul Ilmi Hilkatul Ilmi Hilkatul Ilmi Idha Kusumawati Iis Wahyuningsih Ilmi, Hilkatul Indah Tantular Isnaeni Isnaeni Kasmawati, Henny Kholis Amalia Nofianti Lahardo, Devanus Laura Wihanto Lidya Tumewu Malaka, Muhammad Hajrul Maria Lucia Ardhani Dwi Lestari Marsih Wijayanti Masyitah Hamidah Miatmoko, Andang Misgiati, Misgiati Munandar, Tristiana Erawati Myrna Adianti Nasrul Wahdi Neni Purwitasari Ni Luh Rustini Ni Putu Ariantari Nike Puliansari Nur Illiyyin Akib Nur Suci Lestari Paramita, Diajeng Putri Pratiwi Soesilawati Purwitasari, Neni Purwitasari, Neny Retno Sari Retno Widyowati Rice Disi Oktarina Riesta Primaharinastiti, Riesta Rina Puspitasari Rini Hamsidi Roihatul Mutiah Sabar Deyulita Sabarudin Sabarudin Siti Zulaikah SOFIANA SARI Subhan Rullyansyah Suciati Suciati Suciati Suciati Sukardiman Suryanto, Suryanto Syahrani, Achmad Taslim Ersam Tri Widiandani Tutiek Purwanti Tutik Sri Wahyuni Utami Islamiati W Wahyuni, W Wicaksana, Firman Widjiati Widjiati Widjiati Widjiati Wiwied Ekasari Yusuf Alif Pratama