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EFEKTIVITAS INTERVENSI GARAM IODIUM MELALUI RUMAH TANGGA TERHADAP PENURUNAN TGR PADA ANAK SEKOLAH Basuki Budiman; Komari Komari; M. Saidin
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 27 No. 2 (2004)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v27i2.1411.

Abstract

THE EFFECTIVITY OF IODIZED SALT INTERVENTION THROUGH HOUSEHOLDS TO THE TGR IN SCHOOL CHILDREN.Background: The program to control iodine deficiency disorders (IDD) in Indonesia has been  implemented for more than three decades. The total goiter rate (TGR) was decreased dramatically  from 28.2% in 1982 to 9.8% in 1998. However national survey of iodine deficiency disorders in 2003 found that TGR at national level did not decrease in the period of 1998 to 2003. The number of severe endemic area was decreased, but the number of mild endemic area was increased. This raises the question on the effectivity of the program. The finding can lead to the condusion that using high dose iodine capsule might very effective compared to iodized salts. This paper reports the effect of a three-months iodized salt intervention to the TGR in school children. Objectives: To study the effectivity of iodized salt intervention through households in reducing goiter by palpation to assess the size of the thyroid glands of the goiter in the school children. Methods: A number of 81 families of school children aged 7-12 years were supplied with 2400 grams of iodized salt contained 60 ppm for three months. The study was conducted in endemic iodine deficiency area in Kola Batu, East Java province. The goiter was measured by palpation, and iodine in the urine was analyzed using wet digestion method. The measurements were conducted before and after the intervention.Results: After three months intervention, the goiter rate was decreased by 64.8 percents. There was a significant elevation of iodine excretion in urine level, even in the subjects who had not decreased their goiter gland volume.Conclusions: The study found that the supplementation of iodized salt through the households was very effective in reducing the TGR in school children.
HUBUNGAN KANDUNGAN KLOR SERUM DENGAN HORMON T3/T4 PADA ANAK SEKOLAH DI DAERAH GONDOK ENDEMIK Sukati Saidin; Djoko Pambudi; Sri Martuti; M. Saidin; Susilowati Herman
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 25 No. 1 (2002)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v25i1.1416.

Abstract

ASSOCIATION OF SERUM CHLOR CONTENT WITH T3/T4 HORMONEIN SCHOOL CHILDREN IN IODINE DEFICIENCY REGION.Background: The National Mapping Survey of IDD (1998) found that 7% of sub districts In Indonesia was regarded as severe endemic goitre area (TGR>30%). The high TGR prevalence, beside as a result of low iodized salt consumption (< 30 ppm), It was assumed as the effect of exposure of goitrogenic agent such as chlorine. Based on observation in Karawang sub district showed people had food habit to consume fish contaminated by insecticide used for killing milk fish predator or salted fish which had also contaminated by insecticide used during process of fish drying. Insecticide raw material consists of chlorine which can not be broken by heat or oxidation. Previous study by Gaitan E. (1986) found that chlorine component could inhibit iodine metabolism to form mono and di-iodotyrosine as precursor of T3 and T4 hormones.Objectives: The aim of this study was to find an association of serum chlorine as a reflection of chlorine consumption from daily food with T3 and T4 hormone.Methods: Research design was case control. Study was conducted in Karawang district, West Java. The subject were elementary school children in the fourth, fifth and sixth grades with positive goitre at grade I and II by palpation. Sample size was 140 children divided into two groups, case group (70 children) and control group (70 children). Main data collected was chlorine consumption from daily food, serum chlorine, serum T3 and T4 hormones as well as anthropometries.Results: The result showed that chlorine consumption from food was relatively greater in case group (135.9 ugr/day) than in control group (129.9 ug/day) but statistically it was not significant. Serum chlorine content in case group (1 14.8 mmol/L) was significantly higher than in control group (102.1 mmol/L). Serum T4 hormone in case group (7.3 ug/dl) was significantly lower than in control group (9.5 ug/dl). Serum T3 hormone in case group (1.83 ng/ml) was significantly lower than in control group (2.3 ng/ml). The association of serum chlorine with T4 hormone was low, r = -0.3488 (p=0.001). The association of serum chlorine with T3 hormone was also low, r = -0.2459 (p=0.051).Conclusions: There is less association of serum chlorine with T 3 and T 4 hormones probably caused by other polutant, such as timbal (Pb) and mercury (Hg).Keywords: serum chlor, T3/T4 hormone, iodine deficiency
EFEKTIVITAS PENAMBAHAN VITAMIN A DAN ZAT BESI PADA GARAM YODIUM TERHADAP STATUS GIZI DAN KONSENTRASI BELAJAR ANAK SEKOLAH DASAR M. Saidin; Muherdiyantiningsih Muherdiyantiningsih; Endi Ridwan; Nur Ihsan; Astuti Lamid; Sukati Sukati; Lies Karyadi
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 25 No. 1 (2002)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v25i1.1417.

Abstract

THE EFFECT OF VITAMIN A AND IRON ADDED INTO IODIZED SALT ON NUTRITION STATUS AND LEARNING CONCENTRATION OF ELEMENTARY SCHOOL CHILDREN.Background: It was assumed that in some areas of Indonesia previously recognized as area of endemic goitre, thenutrition problem in that area became more complex due to crisis of economy. Probably some people in that area not only suffering from 100 but also vitamin A and iron deficiency. In this condition intervention of multinutrient is more reasonable than of single nutrient in improving nutrition status.Objectives: The aim of this study was to investigate the effect of vitamin A and iron added into iodized salt on iodine status and learning concentration of elementary school children in moderate endemic goiter area.Methods: The study design was "field trial". Study sites covered two subdistricts, namely Nagak subdistrict and Pelabuhan ratu subdistrict of Sukabumi District, West Java. A total of 221 boys and girls students in the fourth, fifth and sixth grades with positive goitre at grade I, by palpation were randomly assigned into four groups. Each group received different treatment. Group I received iodized salt (43 ppm of Iodine) + 180 ppm of vitamin A (A formula), group II received iodized salt (52 ppm) + 1500 ppm of iron (8 formula), group III received iodized salt only (37 ppm) (C formula) and group IV received iodized salt only (20 ppm). Data evaluation was collected 18 week after intervention.Results: The result of study revealed that proportion of goitre measured by palpation decreased in all groups, group I (14%), group II (7%), group III (21%) as well as group IV (19%). The increment of serum tetraiodotirosine (thyroxine) hormone (T4) of group II (5.02 ug/dl) and group I (4.60 ug/dl) were significantly higher than that of group Ill (2.04 ug/dl) or group IV (2.91 ug/dl). There were no significant differences in the increment of serum triiodotirosine hormone (T3) among group. The haemoglobin level of group II increased (0.36 g/dl), while group I and group IV were slightly decreased. The proportion of student suffering from anemia in group I decreased (25%), while in the other groups increased (4.3% to 9.8%).Conclusions: The increment of T4 was not followed by improvement of learning concentration measured by using 'Weschler Intelligence Scale for Children" method.Keywords: 100 (Iodine deficiency disorder), nutrition status; iodine status; learning concentration; endemic goitre area; palpation; tetraiodotirosine (thyroxine); triiodotirosine; Weschler Intelligence Scale for Children".
PENGARUH PEMBERIAN TABLET BESI DAN VITAMIN E PADA KADAR HEMOGLOBIN DAN STATUS BESI WANITA USIA SUBUR YANG DIDUGA MENDERITA THALASEMIA KARIER M. Saidin; Sukati Sukati; Muherdiyatiningsih Muherdiyatiningsih; Effendi Rustan
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 26 No. 2 (2003)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v26i2.1430.

Abstract

THE EFFECT OF IRON PILL SUPPLEMENTATION ADDED WITH VITAMIN E (ALPHA-TOCOPHEROL) TO HEMOGLOBIN AND IRON STATUS OF CHILDBEARING AGE WOMEN SUSPECTED SUFFERING FROM CARRIER THALASSEMIA.Background: Anemia control programme among pregnant women had been conducting for about three decades, but prevalence of anemia still considered high. It was reported by Nutrition and Food Research Centre (2000) that 37.4% of childbearing women indicated fragility of red blood cell membrane wich assumed related to anemia. One of the vitamins which have positive effect to the wall of red blood cells is vitamin E through its rolle as antioxidant. It was recommended to conduct a study to determine the effect of supplementation of iron pill, "Ferro sulfate" (60 mg elemental iron with 25 mg folic acid) added with vitamin E (20 mg a-tocopherol) to hemoglobin level and iron status of childbearing age of women.Methods: The study design was "Intervention with quacy experiment trial".  The study sites covered 10 villages in Cianjur district of West Java. A total of 210 childbearing age women (19-45 years old) with indication of fragility of red blood cell membrane which was determined by procedure of NESTROF (Naked Eye Single Test Tube Red Cell Osmotic Fragility), divided into two groups (105 women/group). Group I received one iron pill daily and vitamin E twice a week for 10 weeks. While group II received Iron pill only, without vitamin E. Data collection was conducted before and after intervention.Results: After 10 weeks intervention, the average of Hb increament of group I (0.4 g/dl) was slightly higher than that of group II (0.3 g/dl). There was improvement of serum ferritin of both groups with increament 4.3 mg/dl for group I and 7.2 mg/dl for group II. Vitamin E status of both groups still considered low: 3.1 mg/L for group I and 3.1 mg/L for group II. Normal value of serum vitamin E is 5.0 mg/L.Conclusions: Vitamin E (20 mg of a-tocopherol) which was given twice a week bisides daily supplementation of iron pill (60 mg elemental iron of sulfas ferrosus + 25 mg folic acid) for 10 weeks increased the effectiveness of Hb synthesis 1.5 times than that of supplementation of iron only without vitamin E.Keywords: iron supplementation, Hb level, iron status, vitamin E status, NESTROF, fragility of cells membrane 
DETERMINAN STATUS ANEMIA SISWA SLTA DI DKI JAKARTA Fitrah Ernawati; M. Saidin
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 31 No. 2 (2008)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v31i2.1519.

Abstract

Determinants of Anemia Status Among High School Students In Jakarta.Background: The prevalence of anemia among adolescents remains high. The effect of anemia among adolescents especially girls will affect the health status of mothers in the future.Objectives: The study was to analyse the determinants of anemia status among adolescents high school students.Methods: The study design was crosssectional from The Survey Of School Children's Nutritional Status at 10 Cities In Indonesia 2005. The samples of the study were adolescent aged of 15-19 years from high school in Jakarta.Results: The result of the study was that anemia among adolescents high school students were 16%, and the female students had 2.2 (Cl 95%: 1.3-3.7) risk of getting anemia compared to male students.Conclution: Adolescents high school female students need more attention because they have twice the chance to get anemia than male.Keyword: status anemia, female students, high school students