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All Journal Mechatronics, Electrical Power, and Vehicular Technology JURNAL TEKNOLOGI LINGKUNGAN Abdimas Medical Journal of Indonesia CHEMPUBLISH JOURNAL Universa Medicina Jurnal Kreativitas PKM Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Informa: Jurnal Penelitian dan Pengabdian Masyarakat Jurasik (Jurnal Riset Sistem Informasi dan Teknik Informatika) Jurnal Pendidikan Guru Jurnal Farmasi dan Sains Indonesia (JFSI) JOURNAL LA MEDIHEALTICO Jurnal Pengabdian Masyarakat (ABDIRA) Innovative: Journal Of Social Science Research Musyarakah: Journal of Sharia Economics (MJSE) Accounting Analysis Journal Jurnal Sains dan Kesehatan Jurnal Ilmiah Nusantara Research In Management and Accounting (RIMA) Toga Jurnal Keguruan dan Ilmu Pendidikan
Arif Santoso
Research Center for Electrical Power and Mechatronics, Indonesian Institute of Sciences, Komp. LIPI Bandung, Jl. Sangkuriang, Gd. 20. Lt. 2, Bandung 40135
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal Respirasi (JR)

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The Role of Genome-Wide Association Study in Pulmonary Disease Diagnostics: A Review in Medical Bioinformatics Andromeda, Rossalyn; Pratomo, Irandi Putra; Fauzi, Ahmad; Kinasih, Tutug; Prasenohadi, Prasenohadi; Santoso, Arif; Tokumo, Kentaro
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.76-84

Abstract

Biomedical science, which initially required only conventional research in the laboratory, currently involves information technology and has created bioinformatics in its development. Bioinformatics, a branch of biology, quantitatively analyzes information within biological macromolecules using software. Contemporary applications of bioinformatics have advanced biotechnological, medical, and pharmaceutical practices. Among the established applications of bioinformatics is diagnosing lung diseases using the genome-wide association study (GWAS) technique. Owing to sequencing technology and rapid computational methods, this technique is applied to analyze the link between genes with essential traits in the population, thus mapping the target genes to diagnose and treat diseases. The lung diseases diagnosed using GWAS include the responsible locus in asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. Moreover, it can identify the treatment for COPD and suggest a new locus in lung cancer. Advancing the current gene-mapping technology demands genotype and phenotype data to study disease-linked genomes. Currently, bioinformatics is barely known and receives little attention in Indonesia. However, it can grow rapidly through open-source basis data and cross-disciplinary collaboration.
Co-Authors Abdul Azis, Asrul Adib Khusnul Rois, Adib Khusnul Adnan, Endy Amir Mahmud Ana Rima Setijadi Anas Fadli Wijaya Andarini, Sita Andromeda, Rossalyn Anggit Dwi Hartanto, Anggit Dwi Anggita, Dwi Anwar Muqorobin Arfiansyah, Mochammad Aris Asy'hari, Mohammmad Alif Candrakusuma, Muslih Choirul Huda Destiawan, Rian Anggia Diyan Martha , Rahma Djaharuddin, Irawaty Elisna Syahruddin Ema Utami Ermayanti, Sabrina Estiko Rijanto Fathoni, M. Faiz Fauzi Ahmad Muda Haryati Haryati Hendri Maja Saputra Hidayat, Moulid Ida Ayu Putu Sri Widnyani Imanez, Ketzia Adrian Infianto, Andreas Irandi Putra Pratomo IRFAN IDRIS Iskandar, Harun Jasminarti, Ida Ayu Joko Prayitno Susanto Kholifah, Siti Nurriyatul Kinasih, Tutug Kumalasari, Nurul Chamidah Kurniawan, Ferry Dwi Laksmi Wulandari Lihawa, Nurjannah Liong Boy Kurniawan, Liong Boy Lukmanul Khakim Lukni Maulana Martanty Aditya, Martanty MARTHA, RAHMA DIYAN Midriem Mirdanies Milenia Tasya, Syavira Muadhifah, Afidatul Muadifah, Afidatul Muhammad Ilyas Mulyamin, Winda Mustafa, Maulana Saggaf Nawa Suwedi Ngibad, Khoirul Ning Iriyanti Noni Novisari Soeroso Nurdian Susilowati Nurjanah, Mutia Hariani Nurjannah, Mutia Hariani Prasenohadi, Prasenohadi Pratiwi, Widya Wahyu Putra, Andika Chandra Putrawan, Harry Azka Putri, Amalia Eka Rahayu, Selvia Rahmawati, Rahmawati Ratu, Modestus Reba Anindyajati Pratama, Reba Anindyajati Riastus Nayanti Rizqi Andry Ardiansyah Roni Permana Saputra Safitri, Yunita Diyah Santoso, Andintia Aisyah Sari Lestari Sari, Puji Novita Sari, Trianita Setyawan, Ungky Agus Sri Melati Munir Sri Suwarni Sukma Aditya Sulastri Sulastri Syukroni, Azid Teguh Pudji Purwanto Tokumo, Kentaro Tri Rahardjo Sutardi Vikita Windarwati Vita Susanti Widaningsih, Yuyun Wiriansya, Edward Pandu Wulandari, A. Ratna Yustisia, Ika Zaini, Jamal