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All Journal Jurnal Kedokteran Syiah Kuala Jurnal Kesehatan Andalas Berkala Ilmu Kesehatan Kulit dan Kelamin Majalah Kedokteran Andalas Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Sumatera Medical Journal Health and Medical Journal JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Ners Indonesian Journal of Global Health research Indian Journal of Forensic Medicine & Toxicology Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran Jurnal Ilmu Kesehatan Indonesia (JIKSI) International Journal of Public Health Excellence (IJPHE) Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Riset Multidisiplin dan Inovasi Teknologi Vitamedica: Jurnal Rumpun Kesehatan Umum Prosiding Seminar Nasional Unimus Cermin Dunia Kedokteran Frontiers on Healthcare Research
Satya Wydya Yenny
Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Borderline Lepromatous Leprosy with Mild Reversal Reaction in Child Fonna, Nellia; Ariani, Tutty; Rizal, Yosse; Yenny, Satya Wydya
Frontiers on Healthcare Research Vol. 1 No. 1 (2024)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v1.n1.p7-11.2024

Abstract

Background: Childhood leprosy is an important marker of the status of the ongoing leprosy control program, as it is an indicator of active disease transmission in the community. Children are believed to be the most vulnerable group to infection with M. leprae due to their immature or nascent immunity and exposure to intrafamilial contacts. Case report: A 8 years ole male patient presented with hypopigmented patch and erythematous patch with not itchy, not pain, and loss of sensation which increasing more since 1 week ago. Initially 2 months ago, white patch that felt numbness appeared on the back, then white patches wider and spread to the chest, both arms and thighs. Dermatologic finding showed erythematous plaques, hypopigmentation macule with infiltration on cheek, back, both of arms, xerosis cutis. Decreased sensory function was found in the median, ulnar and posteriol tibial nerves. Acid-fast bacilli (AFB) staining revealed bacterial index (BI) +5 and morphological index (MI) 80%. Histopathological examination showed atrophic stratified squamous epithelium, grenz zone, many groups of foamy macrophages reached the fat layer. The patient was diagnosed Morbus Hansen borderline lepromatous leprosy type with mild reversal reaction and treated with MDT-MB drug package, vitamin B complex tablet, zinc tablet, paracetamol tablet, and 10% urea cream on dry skin 2 times a day on dry skin after bath during 2 month and the lesion was reduced. Conclusion: The rate of childhood leprosy continues to be a significant problem. There is a clear need to strengthen early detection, treatment, and regular follow up of these cases in both high and low endemic setting is essential in the prevention of deformities.
Comparison of quality of life, anxiety, and depression levels based on acne vulgaris severity Husna, Annisaul; Yenny, Satya Wydya; Desmawati, Desmawati; Akhyar, Gardenia; Masrul, Masrul; Yulistini, Yulistini
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous unit. Although acne vulgaris is not fatal, it can cause psychological effects. This study aimed to compare the quality of life, anxiety, and depression levels based on the severity of acne vulgaris among medical students at Andalas University. Methods: This was an observational-analytic study with a cross-sectional design. It was conducted from May to June 2023. The population included the third-grade students of the Medical Study Program of the Faculty of Medicine, Andalas University, who had acne vulgaris. The respondents were 70 people, recruited with consecutive sampling techniques. This research used Lehmann classifications to classify acne severity, the Cardiff Acne Disability Index (CADI) to assess quality of life, and the Depression Anxiety Stress Scale (DASS-21) to assess anxiety and depression. The statistical analysis used the Kolmogorov-Smirnov test. Results: Most female respondents, aged 20 years old, experienced mild acne vulgaris (84.3%). Additionally, the respondents predominantly had mild quality of life disorders (80%), normal anxiety level (32.9%), and normal depression level (52.9%). The Kolmogorov-Smirnov test found no relationship between the severity of acne vulgaris with quality of life (p = 0.076), anxiety level (p = 0.623), and depression level (p = 0.751). Conclusion: The results showed that most respondents had mild acne vulgaris, mild impairment in quality of life, normal anxiety level, and normal depression level. Statistical tests revealed no significant association between the severity of acne vulgaris and these variables.
Community Empowerment of Nagari Salimpek in Developing a Herbal Cosmetic Village Based on Family Medicinal Plants (TOGA) Yenny, Satya Wydya; Gustia, Rina; Rahmatini; Usman, Elly; Asri, Ennesta; Akhyar, Gardenia; Ariani, Tutty; Sari, Mutia; Sari, Indah Indria; Yossy, Vesri; Julia, Dwi Sabtika; Ashar, Miranda; Taria, Sari Almira
Warta Pengabdian Andalas Vol 33 No 1 (2026)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.33.1.67-74.2026

Abstract

Nagari Salimpek in Alahan Panjang, West Sumatra, has a potential for wellness tourism due to its rich biodiversity, especially medicinal and cosmetic plants. However, community awareness in managing Family Medicinal Gardens (TOGA) remain limited, with only three of twenty household groups actively cultivating herbal plants. This condition emphasizes the need for community empowerment to optimize health and economic benefits from local resources. This community service program aimed to enhance local capacity in cultivating and processing TOGA as the basis for developing a Herbal Cosmetic Village. The programme began on 19 July 2025 and was evaluated over six months. Activities included educational sessions on TOGA utilization, training on herbal and cosmetic plant processing, distribution and planting of herbal seeds, and the signing of a Memorandum of Agreement (MoA) with local stakeholders. A pre-test and post-test evaluation involving 31 participants showed significant improvement in knowledge, with understanding of the “herbal center village” concept rising from 29% to 55% and awareness of Nagari Salimpek’s potential increasing from 32% to 77%. Overall, participants gained broader insights into the role of TOGA in health, cosmetics, and economic development. These results highlight the importance of continued education, mentorship, and government support to establish Nagari Salimpek as a model Herbal Cosmetic Village for wellness tourism.
Determinan Perilaku dalam Kerangka Telekonsultasi untuk Infeksi Menular Seksual pada Lelaki Suka Lelaki di Kota Batam Made Tantra Wirakesuma; Herwandi Herwandi; Satya Wydya Yenny; Rima Semiarty
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

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Abstract

Infeksi Menular Seksual masih menjadi masalah kesehatan masyarakat yang signifikan pada komunitas Lelaki Suka Lelaki, yang dipengaruhi oleh tingginya perilaku seksual berisiko, rendahnya pemanfaatan skrining rutin, stigma sosial di masyarakat, serta keterbatasan akses terhadap layanan kesehatan konvensional. Kondisi tersebut menimbulkan hambatan psikososial dan struktural dalam upaya deteksi dini Infeksi Menular Seksual. Perkembangan teknologi kesehatan menempatkan telekonsultasi sebagai pendekatan potensial untuk mengatasi hambatan tersebut, Namun demikian, kerangka telekonsultasi berbasis perilaku untuk deteksi dini IMS pada kelompok LSL belum dirumuskan secara jelas. Penelitian ini bertujuan untuk mengembangkan kerangka tersebut di Kota Batam. Penelitian ini menggunakan pendekatan kuantitatif dengan mengeksplorasi determinan perilaku dan respons komunitas terhadap layanan telekonsultasi sebagai dasar pengembangan telekonsultasi. Hasil penelitian menunjukkan bahwa kenyamanan, kerahasiaan, dan kemudahan akses merupakan faktor utama yang memengaruhi penerimaan layanan telekonsultasi. Determinan ini diharapkan dapat menjadi landasan pengembangan kerangka telekonsultasi berbasis perilaku untuk mendukung deteksi dini dan pencegahan IMS serta dapat diadopsi dalam layanan kesehatan berbasis digital.
Hubungan Ekspresi Ki-67 dan Tipe Stroma Peritumoral dengan Varian Histopatologik Karsinoma Sel Basal Silvi Yelitha; Salmiah Agus; Satya Wydya Yenny
Majalah Patologi Indonesia Vol 27 No.1, Januari 2018
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

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Abstract

Latar belakangKarsinoma sel basal (KSB) merupakan keganasan kulit tersering pada manusia. Walaupun jarang bermetastasis KSB terutama varian agresif bersifat destruksi lokal dan dapat terjadi kekambuhan. Mekanisme terjadinya varian KSB agresif dan non-agresif masih belum dimengerti, diduga tingginya tingkat proliferasi sel yang berperan dalam patogenesis tumor ini. Tingkat proliferasi sel dapat dinilai dengan ekspresi Ki-67. Sel tumor yang menginfiltrasi stroma akan menimbulkan reaksi sel stroma peritumoral. Belum diketahui secara pasti tipe stroma peritumoral yang berperan pada varian KSB.Penelitian ini bertujuan untuk menentukan apakah terdapat hubungan ekspresi Ki67 dan tipe stroma peritumoral dengan varian histopatologik KSB.MetodeSampel yang digunakan sebanyak 40 terdiri atas 20 sampel KSB agresif dan 20 sampel KSB non agresif. Sampel diwarnai dengan pewarnaan imunohistokima (IHK) Ki-67 dan histokimia (van Gieson dan Alcian Blue).HasilKSB agresif lebih banyak mengekspresikan Ki-67 tinggi (78,3%) dan memiliki stroma tipe desmoplasia (66,7%), sedangkan KSB non-agresif lebih banyak mengekspresikan Ki-67 rendah (88,2%) dan memiliki stroma tipe miksoid (70%).KesimpulanSecara klinikopatologik ekspresi Ki-67 dan tipe stroma peritumoral berperan untuk membedakan KSB varian agresif dengan non-agresif.
Hubungan Ekspresi Ki-67 dan E-Cadherin dengan Kedalaman Invasi Melanoma Malignum Berdasarkan Clark Level Santy Saberko; Salmiah Agus; Satya Wydya Yenny
Majalah Patologi Indonesia Vol. 28 No. 3, September 2019
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

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Abstract

BackgroundMalignant melanoma (MM) is a neoplasia derived from melanocytes. This is the most aggressive cancer ofskin. Even small tumors may have a tendency to metastasize and thus lead to a relatively unfavorableprognosis. Malignant melanoma depth of invasion based on Clark level is one of the important prognosticfactors to determine survival rate of MM patient. Determination of invasion based on this Clark level issubjective, more objective checks such as Ki-67 and E-Cadherin are required. This examination isexpected to see the risk of metastasis in MM. Cell proliferation is the main key for tumor progression and itcan be measured with Ki-67 expression. E-cadherin is one of transmembrane protein that plays importantrole in metastasis. The purpose of this study is to determine correlation between Ki-67 and E-Cadherinexpression with depth of invasion of malignant melanoma based on Clark level.MethodsThis is cross sectional study in Padang and Jakarta, with 42 cases of malignant melanoma which havebeen diagnosed in Pathology Anatomic Laboratory in West Sumatera. Samples were obtained fromparaffin block of or tissue from surgery and have been reviewed depth of invasion based on the Clark level.These samples were divided into I-V Clark level group. Ki-67 expression of cells nuclei and expression ofE-Cadherin of cells membrane were analyzed using immunohistochemistry assay. One Way Annovabivariate statistical analysis were used and value p<0.05 were considered significant.ResultsPositive Ki-67 expression were found in 42 cases, 6 samples with II Clark level, 8 samples with III Clarklevel, 19 samples with IV Clark level, 9 samples with V Clark level. Malignant melanomas were mostlyfound in male 60-79 age group and depth of invasion in IV Clark level. Positive E-Cadherin expression in IIClark level. There was significant correlation between Ki-67 and E-Cadherin
The Relationship Between Post-Acne Scars and Quality of Life Among Medical Students of FK UNAND, Padang, Indonesia Salsabila Aulia Kasbina; Satya Wydya Yenny; Hendra Permana; Aswiyanti Asri; Qaira Anum; Yulistini
International Journal of Public Health Excellence (IJPHE) Vol. 6 No. 1 (2026): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v6i1.1942

Abstract

Post-acne scars are a condition of skin layer damage due to the healing process of acne vulgaris, causing the skin to appear depressed. This condition disrupts facial aesthetics and may become permanent, thereby affecting the patient’s psychological condition and quality of life. This study aimed to determine the relationship between the severity of post-acne scars and the quality of life among medical students of FK UNAND, Padang, Indonesia. This study was an analytic observational study with a cross-sectional design conducted from June to December 2023. The population consisted of medical students of FK UNAND batch 2020–2022 who had acne scars. The total sample was 88 respondents selected using consecutive sampling. Data were collected using the Facial Acne Scar Quality of Life (FASQOL) questionnaire and Dysmorphic Concern Questionnaire (DCQ). Statistical analysis was performed using One-Way ANOVA and Fisher’s Exact Test. The results showed that most respondents were female and aged 21 years. The majority experienced mild acne scars (46.6%). The mean FASQOL score was 14.11. Most respondents felt disturbed by the presence of acne scars on their face. The DCQ results showed that 88.6% of respondents had no dysmorphic disorder features. There was no significant relationship between acne scar severity and quality of life (p=0.938) nor dysmorphic disorder (p=0.241). The study concluded that there was no relationship between the severity of post-acne scars and the quality of life among medical students of FK UNAND, Padang, Indonesia
Utilization of Fruit Extracts for Sunscreen Satya Wydya Yenny; Fauzana Nazifah
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.5561

Abstract

ABSTRACT Indonesia is one of the countries with high exposure to sunlight, and most of its population works outdoors, making skin protection necessary. While sunlight provides benefits, it also has harmful effects on the skin if exposed excessively. Ultraviolet rays, UVB and UVA, work synergistically to damage the skin, thus requiring prevention or protection to reduce the negative impacts of radiation. Excessive sun exposure is the main exogenous mediator of skin damage. The negative effects of sun exposure on the skin lead to various skin problems such as darkening, wrinkles, dullness, and the appearance of dark brown spots, and it can even cause skin cancer. Therefore, using sunscreen is crucial as it can prevent UV rays from penetrating the skin. This study uses a literature review design, where relevant scientific articles are analyzed to explore the potential of natural ingredients as sunscreen agents. A total of 9 articles were collected from various databases, including PubMed, ScienceDirect, and Google Scholar, using specific keywords related to UV protection, natural sunscreen, and bioactive compounds in plants. The selection of articles was based on inclusion and exclusion criteria, ensuring that only recent and relevant studies were considered. Natural ingredients have not yet been widely utilized in the sunscreen industry. Plants contain substances that can be extracted and serve as a potential source of sunscreen due to their photoprotective properties. This provides insight into the ability of plants to protect the skin through the compounds they contain, such as bioactive compounds like phenolic substances and antioxidants.
Co-Authors Agustin Vira Agustin Vira Andrini Ariesti Andrini Ariesti Annisa Annisa Anum, Qaira Ariani, Tutty Arimuko, Abraham Ashal, Taufik Ashar, Miranda Asri, Ennesta Astria Rima Rara Yuswir Astria Rima Rara Yuswir Aswiyanti Asri Desmawati Desmawati Dolly Irfandy Dwi Sabtika Julia Ennesta Asri Ennesta Asri Ennesta Asri Erlina Rustam Eryati Darwin Etriyel Myh Etriyel, Etriyel Fathiyyatul Khaira Fathiyyatul Khaira, Fathiyyatul Fatma Sri Wahyuni Fauzana Nazifah Fendri, Sandra Tri Juli Fesdia Sari Fonna, Nellia Fortuna, Fory Frien Refla Syarif Gardenia Akhyar Gusti Revilla Hendra Permana Hendra Tarigan Sibero Hendriati, Hendriati Herwandi Herwandi Husna, Annisaul Ida Rahmah Burhan Indah Indria Sari Indah Indria Sari Irdawati Izrul Julia, Dwi Sabtika Julita Julita Julita Julita Kemala Sayuti Kencana, Indah Kusmarinah Bramono Lestari, Andriani Fuji Lilik Norawati Linosefa Linosefa Made Tantra Wirakesuma Mardhiati Mardhiati Masrul Djalal Melly Maya Sari Mimin Oktaviana Mohammad Rafiequl Haririy Muhammad Fadil Muhammad Farel Brian Nugraha Muhammad Zidan Amriza Mutia Sari Nadya Hasriningrum Triman Nellia Fonna Netty Suharti Norawati, Lilik Noverika Windasari Novian Novian Novian Novian Nur, Fauziah Qaira Anum Rahmah Hidayah Rahmatini . Raja Eka Citra Kalisa Rani, Durrotul Nisa Raveinal Rendra Darma Satria Rendra Darma Satria Rendra Darmasatria Resya I Noer Resya I Noer Ria Afrianti Rika Desviorita Rika Desviorita Rima Semiarty Rina Gustia Rina Gustia Rina Gustia Riri Prima Yolanda Ririn Lausarina Rizal, Yosse Rizki Dwayana Rizki Dwayana Rizkia Chairani Asri Roslaili Rasyid Salmiah Agus Salsabila Aulia Kasbina Salwa Azzahra Santy Saberko Sari, Indah Indria sari, Mutia Septi Mayang Sarry Sigya Octari Silvi Yelitha Siti Rahmawati Sri Lestari Sri Lestari Sugma, Lidya Aprilia Suharmanto Suharmanto Suryani, Yulia Eka Taria, Sari Almira Tobat, Sanubari Rela Triani, Aisha Tutty Ariani Tutty Ariani Utama, Redha Cipta Vesri Yossy Virnanda Trisnorizki Saputra Vitresia, Havriza Wardi, Epi Supri Wati, Westi Permata Wresti Indriatmi B. Makes Yan Wirasati Yenni Raflis Yessy Farina Salim Yessy Farina Salim Yola Fadilla Yosse Rizal Yossy, Vesri Yulistini Yulistini, Yulistini Zainal Hakim