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All Journal Jurnal Kedokteran Syiah Kuala Jurnal Kesehatan Andalas Berkala Ilmu Kesehatan Kulit dan Kelamin Majalah Kedokteran Andalas Majalah Patologi Indonesia Sumatera Medical Journal Health and Medical Journal JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Ners Indonesian Journal of Global Health research Indian Journal of Forensic Medicine & Toxicology Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran Jurnal Ilmu Kesehatan Indonesia (JIKSI) International Journal of Public Health Excellence (IJPHE) Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Riset Multidisiplin dan Inovasi Teknologi Vitamedica: Jurnal Rumpun Kesehatan Umum Prosiding Seminar Nasional Unimus Cermin Dunia Kedokteran Frontiers on Healthcare Research
Satya Wydya Yenny
Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Andalas/Dr. M. Djamil General Hospital, Padang, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Hubungan Ekspresi Ki-67 dan E-Cadherin dengan Kedalaman Invasi Melanoma Malignum Berdasarkan Clark Level Santy Saberko; Salmiah Agus; Satya Wydya Yenny
Majalah Patologi Indonesia Vol. 28 No. 3, September 2019
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

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Abstract

BackgroundMalignant melanoma (MM) is a neoplasia derived from melanocytes. This is the most aggressive cancer ofskin. Even small tumors may have a tendency to metastasize and thus lead to a relatively unfavorableprognosis. Malignant melanoma depth of invasion based on Clark level is one of the important prognosticfactors to determine survival rate of MM patient. Determination of invasion based on this Clark level issubjective, more objective checks such as Ki-67 and E-Cadherin are required. This examination isexpected to see the risk of metastasis in MM. Cell proliferation is the main key for tumor progression and itcan be measured with Ki-67 expression. E-cadherin is one of transmembrane protein that plays importantrole in metastasis. The purpose of this study is to determine correlation between Ki-67 and E-Cadherinexpression with depth of invasion of malignant melanoma based on Clark level.MethodsThis is cross sectional study in Padang and Jakarta, with 42 cases of malignant melanoma which havebeen diagnosed in Pathology Anatomic Laboratory in West Sumatera. Samples were obtained fromparaffin block of or tissue from surgery and have been reviewed depth of invasion based on the Clark level.These samples were divided into I-V Clark level group. Ki-67 expression of cells nuclei and expression ofE-Cadherin of cells membrane were analyzed using immunohistochemistry assay. One Way Annovabivariate statistical analysis were used and value p<0.05 were considered significant.ResultsPositive Ki-67 expression were found in 42 cases, 6 samples with II Clark level, 8 samples with III Clarklevel, 19 samples with IV Clark level, 9 samples with V Clark level. Malignant melanomas were mostlyfound in male 60-79 age group and depth of invasion in IV Clark level. Positive E-Cadherin expression in IIClark level. There was significant correlation between Ki-67 and E-Cadherin
The Relationship Between Post-Acne Scars and Quality of Life Among Medical Students of FK UNAND, Padang, Indonesia Salsabila Aulia Kasbina; Satya Wydya Yenny; Hendra Permana; Aswiyanti Asri; Qaira Anum; Yulistini
International Journal of Public Health Excellence (IJPHE) Vol. 6 No. 1 (2026): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v6i1.1942

Abstract

Post-acne scars are a condition of skin layer damage due to the healing process of acne vulgaris, causing the skin to appear depressed. This condition disrupts facial aesthetics and may become permanent, thereby affecting the patient’s psychological condition and quality of life. This study aimed to determine the relationship between the severity of post-acne scars and the quality of life among medical students of FK UNAND, Padang, Indonesia. This study was an analytic observational study with a cross-sectional design conducted from June to December 2023. The population consisted of medical students of FK UNAND batch 2020–2022 who had acne scars. The total sample was 88 respondents selected using consecutive sampling. Data were collected using the Facial Acne Scar Quality of Life (FASQOL) questionnaire and Dysmorphic Concern Questionnaire (DCQ). Statistical analysis was performed using One-Way ANOVA and Fisher’s Exact Test. The results showed that most respondents were female and aged 21 years. The majority experienced mild acne scars (46.6%). The mean FASQOL score was 14.11. Most respondents felt disturbed by the presence of acne scars on their face. The DCQ results showed that 88.6% of respondents had no dysmorphic disorder features. There was no significant relationship between acne scar severity and quality of life (p=0.938) nor dysmorphic disorder (p=0.241). The study concluded that there was no relationship between the severity of post-acne scars and the quality of life among medical students of FK UNAND, Padang, Indonesia
Utilization of Fruit Extracts for Sunscreen Satya Wydya Yenny; Fauzana Nazifah
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.5561

Abstract

ABSTRACT Indonesia is one of the countries with high exposure to sunlight, and most of its population works outdoors, making skin protection necessary. While sunlight provides benefits, it also has harmful effects on the skin if exposed excessively. Ultraviolet rays, UVB and UVA, work synergistically to damage the skin, thus requiring prevention or protection to reduce the negative impacts of radiation. Excessive sun exposure is the main exogenous mediator of skin damage. The negative effects of sun exposure on the skin lead to various skin problems such as darkening, wrinkles, dullness, and the appearance of dark brown spots, and it can even cause skin cancer. Therefore, using sunscreen is crucial as it can prevent UV rays from penetrating the skin. This study uses a literature review design, where relevant scientific articles are analyzed to explore the potential of natural ingredients as sunscreen agents. A total of 9 articles were collected from various databases, including PubMed, ScienceDirect, and Google Scholar, using specific keywords related to UV protection, natural sunscreen, and bioactive compounds in plants. The selection of articles was based on inclusion and exclusion criteria, ensuring that only recent and relevant studies were considered. Natural ingredients have not yet been widely utilized in the sunscreen industry. Plants contain substances that can be extracted and serve as a potential source of sunscreen due to their photoprotective properties. This provides insight into the ability of plants to protect the skin through the compounds they contain, such as bioactive compounds like phenolic substances and antioxidants.
Co-Authors Agustin Vira Agustin Vira Andrini Ariesti Andrini Ariesti Annisa Annisa Anum, Qaira Ariani, Tutty Arimuko, Abraham Ashal, Taufik Ashar, Miranda Asri, Ennesta Astria Rima Rara Yuswir Astria Rima Rara Yuswir Aswiyanti Asri Desmawati Desmawati Dolly Irfandy Dwi Sabtika Julia Ennesta Asri Ennesta Asri Ennesta Asri Erlina Rustam Eryati Darwin Etriyel Myh Etriyel, Etriyel Fathiyyatul Khaira Fathiyyatul Khaira, Fathiyyatul Fatma Sri Wahyuni Fauzana Nazifah Fendri, Sandra Tri Juli Fesdia Sari Fonna, Nellia Fortuna, Fory Frien Refla Syarif Gardenia Akhyar Gusti Revilla Hendra Permana Hendra Tarigan Sibero Hendriati, Hendriati Herwandi Herwandi Husna, Annisaul Ida Rahmah Burhan Indah Indria Sari Indah Indria Sari Irdawati Izrul Julia, Dwi Sabtika Julita Julita Julita Julita Kemala Sayuti Kencana, Indah Kusmarinah Bramono Lestari, Andriani Fuji Lilik Norawati Linosefa Linosefa Made Tantra Wirakesuma Mardhiati Mardhiati Masrul Djalal Melly Maya Sari Mimin Oktaviana Mohammad Rafiequl Haririy Muhammad Fadil Muhammad Farel Brian Nugraha Muhammad Zidan Amriza Mutia Sari Nadya Hasriningrum Triman Nellia Fonna Netty Suharti Norawati, Lilik Noverika Windasari Novian Novian Novian Novian Nur, Fauziah Qaira Anum Rahmah Hidayah Rahmatini . Raja Eka Citra Kalisa Rani, Durrotul Nisa Raveinal Rendra Darma Satria Rendra Darma Satria Rendra Darmasatria Resya I Noer Resya I Noer Ria Afrianti Rika Desviorita Rika Desviorita Rima Semiarty Rina Gustia Rina Gustia Rina Gustia Riri Prima Yolanda Ririn Lausarina Rizal, Yosse Rizki Dwayana Rizki Dwayana Rizkia Chairani Asri Roslaili Rasyid Salmiah Agus Salsabila Aulia Kasbina Salwa Azzahra Santy Saberko Sari, Indah Indria sari, Mutia Septi Mayang Sarry Sigya Octari Silvi Yelitha Siti Rahmawati Sri Lestari Sri Lestari Sugma, Lidya Aprilia Suharmanto Suharmanto Suryani, Yulia Eka Taria, Sari Almira Tobat, Sanubari Rela Triani, Aisha Tutty Ariani Tutty Ariani Utama, Redha Cipta Vesri Yossy Virnanda Trisnorizki Saputra Vitresia, Havriza Wardi, Epi Supri Wati, Westi Permata Wresti Indriatmi B. Makes Yan Wirasati Yenni Raflis Yessy Farina Salim Yessy Farina Salim Yola Fadilla Yosse Rizal Yossy, Vesri Yulistini Yulistini, Yulistini Zainal Hakim