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FORMULASI DAN EVALUASI FISIK MASKER GEL PEEL OFF EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus Polyrhizus) Nofriyanti - Nofriyanti; wira noviana suhery; nesa agistia; wildan khairi muhtadi
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 2 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i2.1741

Abstract

Kulit adalah organ penting dari tubuh kita, umumnya wanita menginginkan kulit yang bersih dan cerah terutama pada kulit wajah, salah satu sediaan kosmetik untuk menjaga kebersihan dan perawatan kulit wajah adalah masker wajah. Jenis masker wajah yang praktis digunakan yaitu masker gel yang setelah kering dapat langsung dikelupas atau biasa dikenal dengan sebutan masker gel peel off. Masker gel peel off merupakan masker gel yang mudah dalam penggunaannya, setelah kering masker dapat langsung dilepas dan menghilangkan sisa-sisa kotoran yang menempel pada permukaan kulit wajah. Penelitian ini bertujuan untuk memformulasi sediaan masker gel peel off dengan variasi konsentrasi F1 (3%), F2 (5%) dan F3 (7%), yang memiliki stabilitas fisik yang baik dari ekstrak kulit buah naga merah, serta menegetahui variasi konsentrasi zat aktif manakah yang lebih baik. Dari hasil yang didapatkan selama empat minggu penyimpanan didapatkan F1, F2, dan F3 homogen pada minggu pertama dan kedua penyimpanan, namun pada minggu ketiga sampai keempat penyimpanan sediaan tidak homogen lagi karena membentuk dua bagian yaitu air dan basis, pemeriksaan pH pada sediaan menunjukan bahwa pH masker gel selama empat minggu penyimpanan menunjukan penurunan pH yaitu basis dengan rentang 6,48-5,38, F1 dengan rentang 5,22-4,71, F2 dengan rentang 5,19-4,91, dan F3 dengan rentang 5,06-4,79 tetapi masih dalam range pH kulit yaitu 4,5-6,5. Untuk daya sebar dan waktu mengering tidak masuk dalam syarat masing-masing evaluasi karena sediaan tidak homogen selama penyimpanan empat minggu.
Formulation and Antioxidant Activity Test of Rice Bran Extract Cream from Two Varieties of White Rice Wira Noviana Suhery; Hayu Lestari; Armon Fernando; Fina Aryani; Gressy Novita
Majalah Obat Tradisional Vol 28, No 2 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.84715

Abstract

Rice bran extract contains high antioxidant compounds. Formulation and antioxidant activity testing of cream preparations containing rice bran extract has been carried out. This study aims to formulate and evaluate cream preparations containing bran extract from two varieties of white rice and their antioxidant activity. The white rice varieties used were the Kalpatali variety (FI) and the Rice 64 (FII) variety. There were three cream formulas, namely the basic formula (F0) and the formula containing rice bran extract with a concentration of 3.1% each (FI and FII). Evaluation of cream preparations included organoleptic test, homogeneity, pH, washability, stability, irritation test, and antioxidant activity test. This study showed that FI has an antioxidant activity of 87.23% and FII has an antioxidant activity of 64.08%. Different varieties of rice show differences in antioxidant activity in cream preparations containing bran extract. The best formula is FI which has good physical properties and higher antioxidant activity compared to FII. 
Ciplukan (Physalis angulata L.): Review Tanaman Liar yang Berpotensi Sebagai Tanaman Obat Fadhli, Haiyul; Ruska, Shinta Liana; Furi, Mustika; Suhery, Wira Noviana; Susanti, Emma; Nasution, Musyirna Rahmah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.144

Abstract

Ciplukan (Physalis angulata L.) has been widely used as a traditional medicine in several countries and regions in Indonesia, such as to increase blood flow and relieve body aches, asthma, diabetes, chickenpox, cough medicine, fever, diarrhea, hypertension, and back pain. This article reviews the potential of ciplukan to overcome various health problems. The preparation of this review article uses references from research articles related to the results of phytochemical screening, the isolation of secondary metabolites, and biological activity tests (pharmacology) of Physalis angulata plants reported in the last 10 (ten) years. This plant contains many secondary metabolite compounds isolated from its roots, leaves, stems, and fruits, such as physalin, withanolide, and flavonoid glycoside compounds. Several studies have reported that this plant has biological and pharmacological activities such as antioxidants, toxicity, anticancer, anti-inflammatory, antidiabetic, antidiarrheal, antibacterial, antifibrotic, and anti-hypercholesterolemia.
PEMANFAATAN LIMBAH KULIT BUAH NANAS (Ananas comosus (L) Merr.) SEBAGAI MINUMAN PENCERNAAN PROBIOTIK Fadhli, Haiyul; Suhery, Wira Noviana; Agustini, Tiara Tri; Ningsih, Yozi Fiedya
Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Vol 11 No 2 (2024): Mei
Publisher : Lembaga Penelitian, Penerbitan dan Pengabdian Masyarakat (LP3M) UNSIQ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32699/ppkm.v11i2.6784

Abstract

Conventional fruit processing for food and beverage production often ignores the potential benefits of fruit peels, resulting in the presence of useless waste. Pineapple peel (Ananas comosus L. Merr) is one of the most underutilized by-products, even though it contains valuable compounds such as bromelain, flavonoids, tannins, oxalates, and phytates that have antibacterial and probiotic properties. The purpose of this community service is to provide education to increase the knowledge of the Kualu Nenas Village community about the utilization of pineapple peel waste as a prebiotic drink. The method used is counseling with colored brochure media and a demonstration of making probiotic drinks. The results obtained from 50 respondents were 48 (96%) respondents with low knowledge level, 1 (2%) respondent with sufficient knowledge level, and 1 (2%) respondent with high knowledge level. The bivariate test was carried out using the Wilcoxon method, where the test obtained the results of the p value = 0.000, which can be concluded that there is a difference or there is an effect of giving brochures on public knowledge because the p value <0.005.
Gambaran Tingkat Pengetahuan Waspada Obat Kadaluwarsa dan/atau Rusak pada Siswa SMAN 10 Pekanbaru Mora, Enda; Suhery, Wira Noviana; Agustini, Tiara Tri; Fiedya, Yozi; Sari, Annisa Rahmida; Maulani, Annissa; Sinaga, Giacinta Gracesandy; Pratiwi, Indah Denni; Jumiati, Jumiati; Romadhon, Laili; Lismarianti, Lismarianti; Rahmayani, Rahmayani; Lestari, Rahyu; Rahayu, Yaza Sri; Eranisa, Yenni
Jurnal Pengabdian Masyarakat Indonesia Vol 4 No 5 (2024): JPMI - Oktober 2024
Publisher : CV Infinite Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jpmi.2981

Abstract

Berkurangnya stabilitas suatu obat dapat menyebabkan efek toksik dan efek yang tidak diinginkan lainnya dan salah satu penyebabnya yaitu obat sudah rusak dan melewati masa kadaluwarsa. Saat ini diharapkan agar semua orang memiliki pengetahuan tentang obat kadaluwarsa dan obat rusak dan juga bagaimana penanganan yang harus dilakukan saat ditemukan adanya obat kadaluwarsa dan obat yang sudah rusak. Tujuan dari kegiatan ini untuk melihat pengaruh pemberian media leaflet tentang waspada obat kadaluwarsa dan/atau rusak serta memberikan pengetahuan seputar obat kadaluwarsa dan/atau rusak di SMAN 10 Pekanbaru. Kegiatan pengabdian masyarakat ini dilakukan dengan sistem diskusi dan demonstrasi, dimulai dari pengisian lembar Kuisioner (pre-test), pembagian leaflet, edukasi secara lisan dan diakhiri dengan pengisian lembar Kuisioner (post-test) terkait pemahaman siswa terhadap informasi yang telah disampaikan. Hasil akan dievaluasi berdasarkan skala guttman. Hasil pre-test dan post-test dimana jumlah siswa yang termasuk dalam kategori tinggi meningkat dari 37 siswa (52,11%) menjadi 64 siswa (90,14%) pada nilai post-test. Hal ini menunjukkan bahwa kegiatan penyuluhan telah berhasil meningkatkan pemahaman siswa serta memberikan dampak positif bagi siswa dalam menyikapi permasalahan yang ada terkait cara penyimpanan obat yang benar, mengetahui ciri-ciri obat kadaluwarsa dan rusak, serta cara pemusnahannya.
UJI INHIBITOR ENZIM TIROSINASE EKSTRAK DAN FRAKSI DAUN KEDABU (Sonneratia ovata Backer) SECARA IN-VITRO Mustika Furi; Ainun Alfatma; Rahma Dona; Armon Fernando; Fina Aryani; Rahayu Utami; Septi Muharni; Husnawati; Wira Noviana Suhery; Melzi Octaviani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.529

Abstract

Kedabu leaves (Sonneratia ovata Backer) are known contain secondary metabolites, one of which is phenolic, flavonoid and antioxidant activity. Phenolic, flavonoids and antioxidant are known to inhibit the tyrosinase enzyme. The tyrosinase enzyme is involved in the process of melanogenesis which produces melanin. Melanin can cause hyperpigmentation. To prevent hyperpigmentation, tyrosinase inhibitors are needed. This study aimed to test the tyrosinase enzyme inhibitor in ethanol extract, n-butanol fraction, ethyl acetate fraction, n-hexane fraction of kedabu leaf (Sonneratia ovatta Backer) using L-tyrosine as a substrate. The method used to get ethanol extract using ethanol maceration, while some fractions are obtained using the fractionation method. The test was carried out using L-tyrosine and kojic acid as a positive control with absorption measurements using microplate reader at a wavelength of 492 nm. The results showed that the best tyrosinase inhibitory activity was produced by the ethyl acetate fraction with an IC50 value of 18,82 g/mL, followed by the n-butanol fraction with an IC50 value of 24,42 g/mL, and the n-hexane fraction with an IC50 value. 28,77 g/mL, ethanol extract with an IC50 value of 99,09 with a strong category for all samples compared with kojic acid as a positive control with an IC50 value of 30,09 g/mL.
PENINGKATAN PENGETAHUAN MASYARAKAT MENGENAI KEAMANAN PENGGUNAAN OBAT HERBAL SAAT PUASA DI PUSKESMAS SIAK HULU II KABUPATEN KAMPAR Suhery, Wira Noviana; Almurdani, Muhammad; Nofriyanti, Nofriyanti; Utami, Rahayu; Pratama, Hafizh Yandi; Febbyola, Flara; Wahidah, Lutfiana Nurul; Andrea, Kamilah Dzikra; Azzahra, Fayza Salwa; Anggraini, Hadistri Sekar; Salsabila, Helmaria Putri; Fazira, Intan; Sirait, Indri Hotma Novida; Milianty, Jesy
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 9 (2025): BESIRU : Jurnal Pengabdian Masyarakat, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i9.1849

Abstract

Pengabdian Masyarakat ini telah dilakukan di Puskesmas Siak Hulu II, Kecamatan Siak Hulu, Kabupaten Kampar, Provinsi Riau. Pengabdian masyarakat ini dilakukan dengan tujuan agar masyarakat dapat mengetahui keamanan penggunaan obat herbal saat berpuasa. Kegiatan dilaksanakan tanggal 14 Maret 2025 di UPTD Puskesmas Siak Hulu II, Kampar, Provinsi Riau. Sasaran dalam kegiatan ini adalah masyarakat yang datang ke UPTD Puskesmas Siak Hulu II, Kabupaten Kampar, Provinsi Riau yang berjumlah 40 orang. Bentuk kegiatan berupa pemberian edukasi lisan terkait dengan keamanan penggunaan obat herbal saat berpuasa dan pembagian brosur sebagai media edukasi. Untuk mengetahui pemahaman masyarakat diberikan pretest dan posttest. Hasil sosialisasi yang dilakukan di Puskesmas UPT II Siak Hulu menunjukkan adanya peningkatan pemahaman masyarakat, dan dapat disimpulkan bahwa kegiatan penyuluhan berjalan dengan baik.
Edukasi dan Penyuluhan Diabetes Mellitus Kepada Masyarakat Desa Empat Balai Kecamatan Kuok Kabupaten Kampar Riau Husnawati, Husnawati; Susanty, Adriani; Sari, Seftika; Thamrin, Thamrin; Suheri, Wira Noviana; Izrawati, Izrawati; Delvi, Kasma Muria; Dirmaningsih, Septi; Ngazizah, Yeti Nur; Meridona, Meridona; Sandi, Widya Ari
QISTINA: Jurnal Multidisiplin Indonesia Vol 4, No 1 (2025): June 2025
Publisher : CV. Rayyan Dwi Bharata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57235/qistina.v4i1.6566

Abstract

Diabetes Mellitus (DM) is a non-communicable disease with increasing prevalence, particularly in rural areas with limited access to health information and services. This community service activity aimed to improve the knowledge of residents in Empat Balai Village, Kuok Subdistrict, Kampar Regency, Riau, regarding DM, its risk factors, and prevention efforts through an educational and participatory community-based approach. The method involved direct counseling, group discussions, and pre-test and post-test assessments to evaluate participants' understanding. The results indicated a significant improvement in knowledge, with the average score increasing from 6.7 (pre-test) to 8.98 (post-test). The education program successfully dispelled common myths, raised awareness of healthy lifestyles, and fostered positive perceptions of both medical and non-medical treatment options. The enthusiastic response from the community demonstrated the effectiveness of this approach in promoting health and preventing non-communicable diseases. This activity highlights the importance of collaboration between students, healthcare workers, and local authorities in public health education and the need for sustained outreach programs.
PEMANFAATAN LIMBAH KULIT BUAH NANAS (Ananas comosus (L) Merr.) SEBAGAI MINUMAN PENCERNAAN PROBIOTIK Fadhli, Haiyul; Suhery, Wira Noviana; Agustini, Tiara Tri; Ningsih, Yozi Fiedya
Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Vol 11 No 2 (2024): Mei
Publisher : Lembaga Penelitian, Penerbitan dan Pengabdian Masyarakat (LP3M) UNSIQ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32699/ppkm.v11i2.6784

Abstract

Conventional fruit processing for food and beverage production often ignores the potential benefits of fruit peels, resulting in the presence of useless waste. Pineapple peel (Ananas comosus L. Merr) is one of the most underutilized by-products, even though it contains valuable compounds such as bromelain, flavonoids, tannins, oxalates, and phytates that have antibacterial and probiotic properties. The purpose of this community service is to provide education to increase the knowledge of the Kualu Nenas Village community about the utilization of pineapple peel waste as a prebiotic drink. The method used is counseling with colored brochure media and a demonstration of making probiotic drinks. The results obtained from 50 respondents were 48 (96%) respondents with low knowledge level, 1 (2%) respondent with sufficient knowledge level, and 1 (2%) respondent with high knowledge level. The bivariate test was carried out using the Wilcoxon method, where the test obtained the results of the p value = 0.000, which can be concluded that there is a difference or there is an effect of giving brochures on public knowledge because the p value <0.005.
Pembuatan dan evaluasi masker gel peel-off ekstrak bekatul padi ketan merah (Oryza sativa L var. Glutinosa) menggunakan gelling agent polivinil alkohol (PVA) Suhery, Wira Noviana; Ulfa, Rodhia; Saputri, Sandry Eka
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.364

Abstract

Gamma oryzanol and anthocyanin are bioactive components contained in red sticky rice bran (Oryza sativa L var. Glutinosa). These two ingredients function as natural antioxidants. Peel-off gel mask containing red glutinous rice bran extract is formulated with varying concentrations of polyvinyl alcohol F1 12%, F2 14%, and F3 16% as gelling agent. This research aims to formulate a peel-off gel mask and carry out an evaluation to obtain the best formula physically and with the highest antioxidant activity. Each formula was tested for organoleptic, homogeneity, pH value, physical stability during storage, spreading power and drying power of the preparation and skin irritation testing. The research results showed that F3 was the best formula in terms of physical and antioxidant activity with an inhibition percentage of 90.5827%. Based on one-way ANOVA analysis, there was a significant difference in antioxidant activity between peel-off gel mask formulas with a significant value of p<0.05.
Co-Authors Adriani Susanty Afriyanti Afriyanti agistia, nesa Agustini, Tiara Tri Ainun Alfatma Alfina Nadia Aminuyati Andrea, Kamilah Dzikra Anggraini, Hadistri Sekar Anita Lukman Armon Fernando Audia Ichsania Achmad Auzal Halim Azkiyah, Revina Tasya Azzahra, Fayza Salwa Benni Iskandar Buddy Giovanni Delvi, Kasma Muria Deni Anggraini deswita Sandra Tsalsabila Ananto Dinda Wijayaningsih Dirmaningsih, Septi Emrizal Enda Mora Eranisa, Yenni Ewika Pritiya Utami Fazira, Intan Febbyola, Flara Fharisti Kirana Fiedya, Yozi Fina Aryani, Fina Fitra Ayu Ningsih Furi, Mustika Ginta Rio Maranti Gressy Novita Gressy Novita Haiyul Fadhli Hayu Lestari Hendra, Rudi Henny Lucida Husnawati Husnawati Husnawati Ismail Marzuki Ivone Permatasari Izrawati, Izrawati Jumiati Jumiati Kismira Hidayati Lestari, Rahyu Liliana Saharani Lismarianti, Lismarianti M Almurdani Maulani, Annissa Meiriza Djohari, Meiriza Melka Febby Arpina Melzi Octaviani Meridona, Meridona Milianty, Jesy Mira Febrina Muhtadi, Wildan Khairi Mustika Furi Musyirna Rahmah Nst nesa agistia Netralis Has Ngazizah, Yeti Nur Ningsih, Yozi Fiedya Nofriyanti Nofriyanti - Nofriyanti Nofriyanti Nofriyanti Novia Risky Nur Novita Dewi Novtafia Endri Nurul Latifah Pratama, Hafizh Yandi Pratiwi, Indah Denni Prima Aulia Putra Rahayu Utami Rahayu Utami Rahayu Utami Rahayu Utami Utami Rahayu, Yaza Sri Rahma Dona Ratna Fitry Yenny Revina Tasya Azkiyah Rinta Maspat Rodhia Ulfa Rodhia Ulfa Romadhon, Laili Rudi Hendra Ruska, Shinta Liana Rusnedy, Rahmayati Salsabila, Helmaria Putri Sandi, Widya Ari Sandry Eka Saputri Nst Saputri, Sandry Eka Sari, Annisa Rahmida Septi Muharni Silvana Anggraini Sinaga, Giacinta Gracesandy Sirait, Indri Hotma Novida Taqqia Sajja Wanda Thamrin Thamrin Tiara Andjelie Wahidah, Lutfiana Nurul Wahyuni Wahyuni Whulan Mudia windi Alfayutia