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All Journal Journal of Food and Pharmaceutical Science Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Majalah Obat Tradisional Jurnal Penelitian Farmasi Indonesia JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JFIOnline Jurnal Ilmu Kefarmasian Indonesia ad-Dawaa : Journal of Pharmaceutical Sciences Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Indonesia QISTINA: Jurnal Multidisiplin Indonesia Jurnal Farmasi Indonesia Journal of Pharmaceutical and Sciences. Journal of Food and Pharmaceutical Sciences Jurnal Pengabdian Masyarakat Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Journal of Pharmascience
Wira Noviana, Wira Noviana
Sekolah Tinggi Ilmu Farmasi (STIFAR) Riau
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Formulasi Lip Tint Alami Ekstrak Stroberi: Peran Tween 80 dan Propilen Glikol Dalam Optimasi Stabilitas dan Aktivitas Antioksidan dengan Menggunakan Design Expert Software Benni Iskandar; Revina Tasya Azkiyah; Wira Noviana Suhery; Rudi Hendra
Journal of Pharmascience Vol. 12 No. 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.23810

Abstract

Penelitian ini bertujuan mengoptimalkan formulasi sediaan lip tint berbasis ekstrak buah stroberi (Fragaria x ananassa) sebagai antioksidan alami melalui variasi konsentrasi Tween 80 dan propilen glikol. Optimasi dilakukan menggunakan perangkat lunak Design Expert versi 13 dengan metode Box-Behnken Design yang menghasilkan 17 formula. Evaluasi mencakup parameter pH, daya sebar, daya lekat, homogenitas, organoleptis, aktivitas antioksidan, uji stabilitas, serta uji iritasi. Hasil skrining fitokimia menunjukkan ekstrak stroberi mengandung alkaloid, flavonoid, fenolik, dan terpenoid, dengan nilai IC₅₀ sebesar 188,29 µg/mL yang tergolong antioksidan kategori sedang. Formula optimum diperoleh pada konsentrasi Tween 80 sebesar 8% dan propilen glikol 5%, dengan prediksi pH 5,64, daya lekat 0,67 detik, daya sebar 5,65 cm, serta nilai desirability 1,00. Hasil verifikasi menunjukkan kesesuaian dengan prediksi dan memenuhi persyaratan mutu sediaan lip tint, baik dari aspek fisik, stabilitas, maupun keamanan. Studi ini membuktikan bahwa ekstrak stroberi berpotensi sebagai pewarna alami sekaligus antioksidan dalam formulasi lip tint yang stabil dan aman digunakan. Kata Kunci: Lip Tint, Fragaria X Ananassa, Pewarna Alami, Antioksidan, Box- Behnken Design This study aimed to optimize the formulation of a lip tint preparation using strawberry (Fragaria x ananassa) extract as a natural antioxidant by varying the concentrations of Tween 80 and propylene glycol. Optimization was carried out using Design Expert version 13 with the Box-Behnken Design method, resulting in 17 formulations. Evaluations were conducted on pH, spreadability, adhesion, homogeneity, organoleptic properties, antioxidant activity, stability, and irritation tests. Phytochemical screening revealed that strawberry extract contains alkaloids, flavonoids, phenolics, and terpenoids, with an IC₅₀ value of 188.29 µg/mL, classified as a moderate antioxidant. The optimum formula was obtained with 8% Tween 80 and 5% propylene glycol, predicting a pH of 5.64, adhesion of 0.67 seconds, spreadability of 5.65 cm, and a desirability value of 1.00. Verification results showed consistency with predictions and met the requirements of a lip tint preparation in terms of physical properties, stability, and safety. These findings demonstrate that strawberry extract has potential as a natural colorant and antioxidant in the formulation of stable and safe lip tint products. 
KOLEST (KONTROL LEMAK SEHAT TUBUH): PENGABDIAN MASYARAKAT DAN PEMBERIAN EDUKASI BAHAYA KOLESTEROL PADA MASYARAKAT KOTA PEKANBARU Benni Iskandar; Audia Ichsania Achmad; Fharisti Kirana; Fitra Ayu Ningsih; Ismail Marzuki; Kismira Hidayati; Liliana Saharani; Melka Febby Arpina; Tiara Andjelie; Wahyuni Wahyuni; Whulan Mudia; Wira Noviana Suhery; Rahmayati Rusnedy; Mustika Furi
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 3 (2025): Volume 6 No 3 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i3.44592

Abstract

Kolesterol  adalah molekul  lipofilik  yang  sangat  penting  bagi  kehidupan  manusia yang memiliki banyak peran dan berkontribusi pada sel yang berfungsi normal. Kolesterol berfungsi sebagai molekul precursor dalam sintesis vitamin D, hormon steroid (kortisol, aldosteron dan androgen adrenal) dan hormon   seks   (testosteron,   estrogen,   dan   progesteron).   Kolesterol   juga   merupakan konstituen   garam   empedu   yang   digunakan   dalam   pencernaan   untuk   memfasilitasi penyerapan vitamin A, D, E dan K yang larut dalam lemak. Tujuan dilakukannya pengabdian ini untuk meningkatkan pengetahuan masyarakat mengenai pentingnya kontrol lemak dengan gaya hidup sehat untuk mengurangi resiko tingginya kadar kolesterol dalam darah. Kegiatan pengabdian dilakukan dengan sistem konseling dengan memberikan Leaflet kepada Masyarakat di Stadion Utama. Dimulai dari pengisian lembar Checklist (pre-test), pembagian leaflet, edukasi secara lisan terkait judul yang diangkat yaitu “KOLEST (Kontrol Lemak Sehat Tubuh)”, selanjutnya Masyarakat diminta untuk mengisi lembar Checklist (post-test) terkait pemahaman masyarakat terhadap informasi yang telah disampaikan dan diakhiri dengan melakukan cek kolesterol gratis. Berdasarkan hasil yang diperoleh terdapat pengaruh peningkatan pengetahuan masyarakat setelah dilakukan pemberian edukasi dengan nilai p value 0,000 yang artinya ada perbedaan yang signifikan.
Impact of SNEDDS formulation variables on physical characterization, drug release, and anti-inflammatory activity: a review Rodhia Ulfa; Benni Iskandar; Gressy Novita; Deni Anggraini; Wira Noviana Suhery; Prima Aulia Putra
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 24 No. 1 (2026): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v24i1.2050

Abstract

Self-nano-emulsifying drug delivery systems (SNEDDS) address the challenges of poor solubility and bioavailability in oral drug delivery. These challenges lead to poor therapeutic results and an increased frequency of dosing. This review assesses the challenges of oral drug delivery due to poor solubility and absorption and the potential of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) to deliver poorly water-soluble drugs. This also entails an assessment of the formulation components of SNEDDS, particularly oils, surfactants, and co-surfactants, and their influence on the physicochemical properties, release profile, stability, and anti-inflammatory activity of the formulation. A thorough assessment of 25 of the most recent primary studies revealed the significant influence of formulation design on the size and distribution of droplets and their subsequent emulsification, drug release, and bioavailability. Oils that are easier to solubilize, along with high HLB surfactants and co-surfactants, such as PEG 400 and Transcutol, are instrumental in producing smaller, stable emulsions that facilitate permeability. Nevertheless, human pharmacokinetic data are lacking, and challenges remain in the large-scale production of solid dosage forms from liquid SNEDDS. This problem is further complicated by the variability of the excipients. The review highlights the need for standardized predictive models and more refined plans for in vivo validation and excipient development. What is unique is the integration of specific information from formulation optimization with translational pharmacological outcomes. This integration has the potential to greatly improve the design and utilization of SNEDDS, thereby expanding its therapeutic benefits.
FORMULASI DAN KARAKTERISASI NANOEMULGEL LIP SERUM CERAMIDE DENGAN OPTIMASI RESPONSE SURFACE METHODOLOGY Sandry Eka Saputri Nst; Wira Noviana Suhery; Deni Anggraini
Jurnal Penelitian Farmasi Indonesia Vol 15 No 1 (2026): Jurnal Penelitian Farmasi Indonesia (JPFI)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) Sekolah Tinggi Ilmu Farmasi Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v15i1.2250

Abstract

Lip skin possesses a thin stratum corneum (10–15 μm) with low ceramide and lipid content, rendering it particularly susceptible to dehydration and environmental damage. This study aimed to develop and characterize a ceramide nanoemulgel lip serum using Response Surface Methodology (RSM) with Simplex Lattice Design (SLD) optimization, and to evaluate its efficacy in improving lip moisture in vivo. Nanoemulsion optimization was performed using Design Expert® v.13.0, with grape seed oil (1–2%), Tween 80 (6–10%), and Kolliphor® RH40 (6–10%) as independent variables, and pH and percent transmittance as responses. The optimal formula comprised grape seed oil 1.346%, Tween 80 7.001%, and Kolliphor® RH40 9.652% (desirability 0.967). The optimized nanoemulsion was incorporated into a nanoemulgel with 0.2% Carbopol 940. Physicochemical evaluation revealed a particle size of 18.1 nm, a low polydispersity index, zeta potential of +2.0 mV, pH 5.5, and viscosity of 386.4 cP. Physical stability was maintained over 12 weeks under three storage conditions without significant change (p>0.05). Irritation testing on 5 panelists yielded negative results. The in vivo efficacy testing demonstrated a statistically significant improvement in lip moisture (p<0.001): ceramide nanoemulgel achieved 22%, compared to base lip serum (11%) and negative control (3.33%).
Gambaran Penggunaan Obat Infeksi Saluran Pernapasan Akut (Ispa) Pada Pasien Pediatri Di Puskesmas Sidomulyo Rawat Jalan Kota Pekanbaru Meiriza Djohari; Wira Noviana Suhery; Ewika Pritiya Utami
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.3696

Abstract

Infeksi Saluran Pernapasan Akut (ISPA) adalah penyakit infeksi yang menyerang salah satu bagian atau lebih dari saluran napas, mulai dari hidung (saluran atas) hingga alveoli (saluran bawah). Infeksi saluran pernapasan akut adalah infeksi yang disebabkan oleh virus dan bakteri. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan obat infeksi saluran pernapasan akut (ISPA) pada pasien pediatri di puskesmas sidomulyo rawat jalan kota pekanbaru. sampel yang digunakan yaitu data pasien pediatri ISPA puskesmas pada tahun 2021 di Puskesmas Sidomulyo Rawat Jalan Kota Pekanbaru. Metode yang digunakan retrospektif dengan teknik purposive sampling. Berdasarkan hasil penelitian yang di lakukan, di dapatkan hasil penggunaan antihistamin 165 obat (31,79%), ekspektoran 156 obat (30,05%), analgetik 103 obat (19,84%), antibiotik 87 obat (16,76%), mukolitik 5 obat (0,96%), bronkodilator 2 obat (0,38%), dan kortikosteroid 1 obat (0,19%). Berdasarkan zat aktif obat didapatkan, CTM 165 obat (31,79%), guafenesin 156 obat (30,05%), paracetamol 103 obat (19,84%), amoxicillin 83 obat (15,99%), ambroxol 5 obat (0,96%), cefadroksil 3 obat (0,57%), salbutamol 2 obat (0,38%) dan eritromisin 1 obat (0,19%).
Pengaruh Jenis Minyak Terhadap Karakterisasi Sifat Fisik dan Disolusi Self-Nanoemulsifying Drug Delivery System (SNEDDS) Asam Fenofibrat Wira Noviana Suhery; Meiriza Djohari; Novia Risky Nur
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.4161

Abstract

The purpose of this study was to determine the effect of oil components of fenofibric acid self nanoemulsifying drug delivery systems. The investigated oils are long chain triglycerides (LCT) and medium chain triglycerides (MCT). The oils used are peanut oil (F1), castor oil (F2), virgin coconut oil (F3), and palm oil (F4). The study showed that the solubility of fenofibric acid in each oil F1 (0.57 ± 0.009 mg/ml), F2 (5.45 ± 0.17 mg/ml), F3 (0.85±0.007 mg/ml), F4 (1.04±0.03 mg/ml. The solubility of fenofibric acid in SNEDDS; F1 (27.72±0.54 mg/ml), F2 (35.50±0.96mg/ml), F3 (29.58±0.47 mg/ml), and F4 (32.14±0.44 mg/ml). The different spontaneous emulsification times were F1 (146.51 ± 2.85 seconds), F2 (37.11 ± 1.83 seconds), F3 (99.98 ± 0.63 seconds), and F4 (56.40 ± 1.71 seconds), and the results of dissolution at 60 minutes are F1 (73.66 ± 0.56%), F2 (96.52 ± 0.34%), F3 (77.87±0.81%), F4 (85.23 ± 0.98%). The type of oil can affect the characterization physical properties and dissolution of fenofibric acid SNEDDS. The best formula was shown by F2, which was a formula containing castor oil as an oil component.
Microemulsion-Based Delivery of Celery (Apium graveolens L.) Extract as a Hair Growth Promoter: Penghantaran Ekstrak Seledri (Apium graveolens L.) Berbasis Mikroemulsi sebagai Promotor Pertumbuhan Rambut Wira Noviana Suhery; Nofriyanti; Nurul Latifah; Mustika Furi; Haiyul Fadhli; Rahayu Utami
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.6831

Abstract

This study aimed to formulate a microemulsion of celery ethanol extract (Apium graveolens L.) and evaluate its physical properties and effects on rabbit hair growth. Four formulations were prepared: three containing celery extract at concentrations of 5% (FI), 7.5% (FII), and 10% (FIII), and one blank formula (F0). The microemulsions were assessed for organoleptic properties, percent transmittance, pH, density, viscosity, rheology, stability (including heating–cooling cycles and centrifugation), skin irritation, and globule size. Hair growth activity was tested in rabbits, and data were analyzed using two-way ANOVA. All formulations demonstrated good physical stability and caused no skin irritation. The results showed that the microemulsions significantly promoted hair growth, with the 10% extract formulation (FIII) showing the most pronounced effect, enhancing hair length by 2.7 times compared to the blank. These findings suggest that celery extract microemulsions, particularly at higher concentrations, are effective in stimulating hair growth.
Penguatan Kesehatan Warga Desa Sungai Petai melalui Inovasi Jamu Instan, Infused Water dan Layanan Pemeriksaan Kesehatan Terpadu Haiyul Fadhli; Wira Noviana Suhery; Benni Iskandar; Silvana Anggraini; Taqqia Sajja Wanda; Rinta Maspat; deswita Sandra Tsalsabila Ananto; windi Alfayutia
Agrokreatif: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 3 (2025): Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agrokreatif.11.3.594-602

Abstract

Degenerative diseases such as hypertension, diabetes mellitus, and gout have developed and threaten the quality of life of the community, especially in rural areas. This community service aims to enhance awareness among the residents of Sungai Petai Village about the benefits of instant herbal medicine, infused water, and health education for early detection and maintaining a healthy lifestyle. The method used is service learning with health counseling, demonstration of instant herbal medicine and infused water, and health checks (blood pressure, blood sugar, and uric acid), followed by a pretest and posttest to assess the improvement of health education, with a pretest and posttest to determine the improvement of knowledge. The results showed that the education significantly improved participants' understanding of diseases and health products, with a considerable and sizable overall increase in knowledge at the posttest (80.83). The health check also showed that some participants had health conditions that required further attention.
Optimization of the Essential Oil Toner Formula from Kaffir Lime Peel (Citrus hystrix DC.) and Evaluation of Its Antibacterial Activity against Propionibacterium acnes Nesa Agistia; Alfina Nadia; Wira Noviana Suhery
Journal of Food and Pharmaceutical Sciences Vol 14, No 4 (2026): J.Food.Pharm.Sci (In Press)
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.26887

Abstract

Acne is a multifactorial skin disease of the pilosebaceous unit. It is a complex inflammatory condition, in which one of the contributing factors is infection by Propionibacterium acnes, which plays a central role in its pathogenesis. Lime peel essential oil is rich in limonene (approximately 32%), which is known for its potent antibacterial activity. This study aims to evaluate the interactive effects of surfactant and co-surfactant concentrations on key physicochemical parameters—namely pH and percentage transmittance- while also identifying the optimal formulation, as well as assessing its physical stability and antibacterial performance. Using a factorial experimental design, Tween 80 (20–25%) and propylene glycol (15–20%) demonstrated interactive effects on the measured responses. Higher concentrations of Tween 80 and propylene glycol resulted in increased pH and percentage transmittance of the toner. Among the variables, Tween 80 was found to be the most influential factor affecting the responses. The optimized toner formulation consisted of 25% Tween 80 and 20% propylene glycol. Verification of the optimal formula using a one-sample t-test showed no significant difference between the predicted values (obtained from Design-Expert) and the experimental results for pH and percentage transmittance, as indicated by a Sig. (2-tailed) value of > 0.05. These results indicate excellent clarity and an ideal pH profile; however, a decrease in pH was observed after 8 weeks of storage. In addition, the incorporation of 15% lime peel essential oil exhibited antibacterial activity, producing an inhibition zone of 21.1 mm against P. acnes.
Optimization of the Essential Oil Toner Formula from Kaffir Lime Peel (Citrus hystrix DC.) and Evaluation of Its Antibacterial Activity against Propionibacterium acnes Nesa Agistia; Alfina Nadia; Wira Noviana Suhery
Journal of Food and Pharmaceutical Sciences Vol 14, No 4 (2026): J.Food.Pharm.Sci (In Press)
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.26887

Abstract

Acne is a multifactorial skin disease of the pilosebaceous unit. It is a complex inflammatory condition, in which one of the contributing factors is infection by Propionibacterium acnes, which plays a central role in its pathogenesis. Lime peel essential oil is rich in limonene (approximately 32%), which is known for its potent antibacterial activity. This study aims to evaluate the interactive effects of surfactant and co-surfactant concentrations on key physicochemical parameters—namely pH and percentage transmittance- while also identifying the optimal formulation, as well as assessing its physical stability and antibacterial performance. Using a factorial experimental design, Tween 80 (20–25%) and propylene glycol (15–20%) demonstrated interactive effects on the measured responses. Higher concentrations of Tween 80 and propylene glycol resulted in increased pH and percentage transmittance of the toner. Among the variables, Tween 80 was found to be the most influential factor affecting the responses. The optimized toner formulation consisted of 25% Tween 80 and 20% propylene glycol. Verification of the optimal formula using a one-sample t-test showed no significant difference between the predicted values (obtained from Design-Expert) and the experimental results for pH and percentage transmittance, as indicated by a Sig. (2-tailed) value of > 0.05. These results indicate excellent clarity and an ideal pH profile; however, a decrease in pH was observed after 8 weeks of storage. In addition, the incorporation of 15% lime peel essential oil exhibited antibacterial activity, producing an inhibition zone of 21.1 mm against P. acnes.
Co-Authors Adriani Susanty Afriyanti Afriyanti agistia, nesa Agustini, Tiara Tri Ainun Alfatma Alfina Nadia Aminuyati Andrea, Kamilah Dzikra Anggraini, Hadistri Sekar Anita Lukman Armon Fernando Audia Ichsania Achmad Auzal Halim Azkiyah, Revina Tasya Azzahra, Fayza Salwa Benni Iskandar Buddy Giovanni Delvi, Kasma Muria Deni Anggraini deswita Sandra Tsalsabila Ananto Dinda Wijayaningsih Dirmaningsih, Septi Emrizal Enda Mora Eranisa, Yenni Ewika Pritiya Utami Fazira, Intan Febbyola, Flara Fharisti Kirana Fiedya, Yozi Fina Aryani, Fina Fitra Ayu Ningsih Furi, Mustika Ginta Rio Maranti Gressy Novita Gressy Novita Haiyul Fadhli Hayu Lestari Hendra, Rudi Henny Lucida Husnawati Husnawati Husnawati Ismail Marzuki Ivone Permatasari Izrawati, Izrawati Jumiati Jumiati Kismira Hidayati Lestari, Rahyu Liliana Saharani Lismarianti, Lismarianti M Almurdani Maulani, Annissa Meiriza Djohari, Meiriza Melka Febby Arpina Melzi Octaviani Meridona, Meridona Milianty, Jesy Mira Febrina Muhtadi, Wildan Khairi Mustika Furi Musyirna Rahmah Nst nesa agistia Netralis Has Ngazizah, Yeti Nur Ningsih, Yozi Fiedya Nofriyanti Nofriyanti - Nofriyanti Nofriyanti Nofriyanti Novia Risky Nur Novita Dewi Novtafia Endri Nurul Latifah Pratama, Hafizh Yandi Pratiwi, Indah Denni Prima Aulia Putra Rahayu Utami Rahayu Utami Rahayu Utami Rahayu Utami Utami Rahayu, Yaza Sri Rahma Dona Ratna Fitry Yenny Revina Tasya Azkiyah Rinta Maspat Rodhia Ulfa Rodhia Ulfa Romadhon, Laili Rudi Hendra Ruska, Shinta Liana Rusnedy, Rahmayati Salsabila, Helmaria Putri Sandi, Widya Ari Sandry Eka Saputri Nst Saputri, Sandry Eka Sari, Annisa Rahmida Septi Muharni Silvana Anggraini Sinaga, Giacinta Gracesandy Sirait, Indri Hotma Novida Taqqia Sajja Wanda Thamrin Thamrin Tiara Andjelie Wahidah, Lutfiana Nurul Wahyuni Wahyuni Whulan Mudia windi Alfayutia