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Suryaningsih Suryaningsih
Universitas Abdurrab
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Journal : Journal of Science and Technology Research for Pharmacy

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Effect of Variation Conditions of The Extraction Process of Morinda Citrifolia L Leaves Using Ultrasound-Assisted Extraction Method (Uae) Buanasari, Buanasari; Dhamayanti, Sonia Murniana Sri; Suryaningsih, Suryaningsih
Journal of Science and Technology Research for Pharmacy Vol 1 No 1 (2021)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jstrp.v1i1.44348

Abstract

Background: Morinda citrifolia L. is widely used as traditional medicine for various diseases. The benefits of noni are studied from the seeds, fruit, leaves and root bark. This leaf active compound is rich in flavonoids, so an effective extraction process is needed to extract it. Conventional extraction generally takes a long time and involves a thermal process that can damage the compound, so it requires extraction with the latest methods, one of which is the use of ultrasonic waves. Aim: This study aims to examine the effect of variations in extraction process conditions on present yield, DPPH scavenging activity, flavonoid content and phenol content of Morinda citrifolia L leaves by varying the solids-solvent ratio (1:10, 1:20, 1:30, dan 1:40 g/mL), and extraction temperature (25, 35, 45, and 55ºC). Method: The process uses the ultrasonic assisted extraction method with 50 %V ethanol for 60 minutes. Result: The highest yield was obtained in the extraction with a solids-solvent ratio of 1:40 g/mL, at an extraction temperature of 55ºC, which was 32.29±0.066%. The highest flavonoid content (173.41±0.615 mg quercetin equivalent/g extract), phenol content (197.00±0.148 mg gallic acid equivalents/g extract) and DPPH scavenging activity (97.65±0.912%) was obtained in the extraction with a solids-solvent ratio of 1:30 g/mL, at an extraction temperature of 25ºC. The best extract measured antioxidant activity and IC50 values obtained with 23.21 µg/mL. Conclusion: The use of the ultrasonic assisted extraction method by selecting the optimal operating conditions greatly increases the amount of active compound uptake required.
Co-Authors Agussalim, Agussalim Ahsari, Dwi Ahmadil Akbar, Muh Alam, Jaya Anisak, Siti Anna S Ranti, Anna S Annissa Valentina Antonius Purwanto Asri, Yoana Nurul Astin Nur Hanifah Buanasari Buanasari, Buanasari Chulsum, Umi Dai, Herlina Damanik, Amsari Dhamayanti, Sonia Murniana Sri Dhea Chandra Dewi, Dhea Chandra Dewi Dodi Apriadi Eka Saputra, Alfian F D Junardy, F D Fachrina Bella Syahputri Fauziandi, Ronald Fikri, Acrian Nuzhatul Fitriah Fitriah Fitriani, Besse Free Dirga Dwatra Frescilia, Tasya Gafar, Tengku Fahrul Hadi Sumarsono Haris, Mustofa Hasanah, Nurjannatul Hasyim, Budi Hendriyani, Feftin Heri Andrianto Herlina, Besse Husnul Khatimah Ikhsan Darmawan Indah Juwairiyah irfan cholid Irsang, Irsang Irwan Irwan Iswan Iswan K, Suprianto. karunia, Erick Kasmiryani Ar, Siti Nur Alifya Khasanah, Amelia Uswatun Kurmalasari, Tety Lantong, Muhammad Adri Loong, Ang Hong Madli, Faerozh Maily, Maily Martanto . Medisa, Rani MEGAWATI, CICILIA DESY Moh. Choirin, Moh. Choirin mufarika, mufarika Muh. Irfandy Azis Mulya, Rizki Afri Mumu, Rudy Musnar Indra Daulay Muthalib, Abd. Azis Nabila, Shalihatun niko, Nikodemos Nikodemus Niko, Nikodemus Nova Zulfahmi, A. Novita Ulfa, Rosi Nugroho, Sulung NUR FITRIANI Nur, Muh. Nurcaya Nurcaya Nurdin Rahman Nursia, Nursia Nurul Fadhilah NURWAHIDAH NURWAHIDAH Panca Wardanu, Adha Pangestoeti, Wahyu Paulina, Irma Putra, Yudithia Dian Putri, Lidya Utami Putri, Rianda Prima Qurdiansyah, Adhitya Rahmawati, Nanik Ramdhan Witarsa Rodiyatun Rodiyatun, Rodiyatun Rolisti, Dinda RR. Ella Evrita Hestiandari Rudianda Sulaeman S M Wasitaatmadja, S M Said, Rahmat Sapariah Saputra, Haidir Shalahuddin Shalahuddin, Shalahuddin Shofiatul Azmi Siti Arieta Sri Wahyuni Sri Wahyuni suryaningsih Syafitri, Rahma Syahida, Nidya Putri Syahputra, Meyranda Teguh Setiandika Igiasi Tri Samnuzulsari Tuti Arlita Valentina, Annisa Vivi Sylvia Purborini Wahyuningsih, Dwi Warni Warlan Sugiyo Wijaya, Insani Sogmawati Wong Lip Wih, Wong Lip Yahya, Glory Yolanda Yayuk Eliyana . Yulasmana, Yoga Yusuf Sobri, Ahmad Zainuri Zainuri, Zainuri Zamhasari, Zamhasari Zulaikha, Layla Imroatu