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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Window of Health : Jurnal Kesehatan JURNAL PENDIDIKAN TAMBUSAI NERSMID: Jurnal Keperwatan dan Kebidanan Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Diagnosis: Jurnal Ilmiah Kesehatan Borneo Journal of Medical Laboratory Technology Indian Journal of Forensic Medicine & Toxicology Wal'afiat Hospital Journal Jurnal EduHealth Jurnal Info Sains : Informatika dan Sains JURNAL ILMIAH GLOBAL EDUCATION Journal of Aafiyah Health Research (JAHR) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) International Journal of Health and Pharmaceutical (IJHP) Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL Fakumi Medical Journal The International Journal of Medical Science and Health Research
Sri Vitayani
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Cytotoxicity Test of Green Betel Leaf Ethanol Extract (Piper Betle L.) Using Shrimp Larvae (Artemia Salina L.) Using The Brine Shrimp Lethality Test (BSLT) Method Ismail, Mardhiyah Adawiyah; Vitayani, Sri; Nur Aulia Amir; Yusriani Mangarengi; Marzelina Karim; Galagher, Mahry
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 1 (2025): February 2025 (Indonesia - Turkey - Malaysia - Australia - Iran)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i1.407

Abstract

The Brine Shrimp Lethality Test (BSLT) method is a preliminary method for screening anticancer compounds by looking at the cytotoxic effect of a sample that will be tested on Artemia salina shrimp larvae. This study aims to evaluate the cytotoxic effect of ethanol extract of green betel leaves (Piper betle L.) on Artemia salina Leach larvae using the Brine Shrimp Lethality Test (BSLT) method. Extraction was carried out by maceration method using 96% ethanol, and phytochemical screening to show the presence of secondary metabolite on green betel leef. Cytotoxicity tests were carried out at five extract concentrations (concentrations of 50 ppm, 100 ppm, 250 ppm, 500 ppm, and 750 ppm). Based on the results of the research carried out, it can be concluded that the results show that the percentage of larvae deaths ranges from 30-80% and the highest mortality was obtained at a concentration of 750 ppm with a total of 26 larval deaths, this death was in line with the increase in concentration. The Lethal Concentration (LC50) value obtained was 121.3317 ppm. In conclusion, green betel leaf extract contains secondary metabolite compounds which cause cytotoxic effects on Artemia salina Leach shrimp larvae with a mortality percentage of 30-80% and the LC50 value is 121.3317 ppm.
Hubungan Pertambahan Berat Badan Ibu Hamil dengan Berat di RSIA Sitti Khadijah Makassar Khomeny, Imran Al Mu’min; Vitayani, Sri; Aulia, Nur; Nurmadilla, Nesyana; Darma, Sidrah
Syifa'Medika Vol 16, No 1 (2025): Syifa Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v16i1.9877

Abstract

Pregnancy involves physical, psychological, and social aspects, with maternal weight gain being an important indicator for assessing maternal health and fetal development. This study aims to analyze the relationship between maternal weight gain during pregnancy and birth weight of infants born at Sitti Khadijah 1 Muhammadiyah Mother and Child Hospital in Makassar. An analytical observational study with a cross-sectional design was conducted, involving 40 pregnant women who gave birth between January and February 2025. Data were collected through medical records and the Mother and Child Health Book, then analyzed using the Chi-square test. The results showed that most mothers experienced weight gain within the normal category (70.7%), and 95% of babies were born with normal birth weight. There was a significant association between maternal weight gain and birth weight, with a p-value of 0.042. The study concluded that normal or higher maternal weight gain is associated with a higher likelihood of giving birth to infants with normal birth weight. This study emphasizes the importance of monitoring maternal weight gain to prevent low birth weight.
The Relationship Between Viral Load Levels and CD4+ Count with the Incidence of Opportunistic Infections in HIV/AIDS Patients at Ibnu Sina Hospital Makassar Daud, Nur Ramahdani; Vitayani, Sri; Harahap, Muhammad Wirawan; Waspodo, Nurelly Noro; Irmayanti, Irmayanti
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1612

Abstract

Background: HIV/AIDS is a global health problem that continues to be a challenge, especially in developing countries. One important aspect in the management of HIV/AIDS is the monitoring of viral load and CD4+ levels which serve as indicators of the patient's immune status. As the disease progresses, HIV/AIDS patients are at high risk of opportunistic infections that can worsen health conditions and shorten life expectancy. Objective: To determine the relationship between viral load and CD4+ levels in HIV/AIDS patients at Ibnu Sina Hospital. Method: Analytic observational research method with cross sectional approach, the research subjects were 10 subjects for viral load examination and 32 subjects for CD4+ examination. Results: The highest percentage of opportunistic infections was in oral candidiasis infection as many as 16 people (50%). The chi-square test showed a significant relationship between CD4+ levels and opportunistic infections in HIV/AIDS patients at Ibnu Sina Hospital Makassar with a p-value of 0.000 while for viral load could not be determined because secondary data were incomplete. Conclusion: There is a significant relationship between CD4+ levels with opportunistic infections in patients with HIV/AIDS at Ibnu Sina Hospital Makassar.
Analysis of complications in type 2 diabetes mellitus patients at Ibnu Sina Hospital in 2023 Handayani, Dewi Sri; Vitayani, Sri; Harahap, Muhammad Wirawan; Gani, Azis Beru; Nur, Muh Jabal
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1664

Abstract

Background: Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia due to decreased insulin secretion or insulin resistance. T2DM can lead to microvascular complications, such as neuropathy, nephropathy, and retinopathy, as well as macrovascular complications, including heart disease, stroke, and peripheral vascular disease. Objective: This study aimed to determine the relationship between age, gender, HbA1c levels, and the duration of T2DM with the complications experienced by T2DM patients at Ibnu Sina Hospital Makassar. Method: This was a descriptive observational study with a cross-sectional design involving 40 T2DM patients. Data were collected using secondary patient records. Results: The most common complication found was diabetic neuropathy, affecting 19 patients (47.5%). Statistical analysis using the chi-square test showed a significant relationship between age and complications (p = 0.002) and between HbA1c levels and complications (p = 0.004). Gender showed no significant relationship with complications. The duration of T2DM could not be analyzed due to incomplete data. Conclusion: Age and HbA1c levels are significantly associated with the occurrence of complications in T2DM patients at Ibnu Sina Hospital in 2023. Regular monitoring and strict glycemic control are essential to minimize the risk of complications.
Analisis Faktor Yang Mempengaruhi Ketidakpatuhan Pengobatan Penderita Kusta Pada Puskesmas Di Makassar Abrar, Muhammad Edwin Raihan; Wahyu, Sri; Aulia, Nur; Vitayani, Sri; Hadi, Santriani
Borneo Journal of Medical Laboratory Technology Vol. 7 No. 2 (2025): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v7i2.9274

Abstract

Kusta (Morbus Hansen) adalah penyakit menular yang disebabkan oleh Mycobacterium leprae, menyerang kulit, saraf tepi, dan jaringan tubuh lainnya. Meskipun dapat diobati secara efektif, ketidakpatuhan dalam pengobatan menjadi hambatan utama dalam upaya eradikasi kusta. Ketidakpatuhan ini disebabkan oleh berbagai faktor, seperti efek samping obat, pengetahuan yang kurang, kurangnya dukungan keluarga, dan kesulitan akses layanan kesehatan. Di Sulawesi Selatan, prevalensi kusta masih tinggi, dan tingkat kepatuhan pengobatan di puskesmas belum optimal. Penelitian ini bertujuan untuk mengetahui faktor-faktor Penyebab ketidakpatuhan pengobatan pasien kusta di puskesmas kassi-kassi. Penelitian ini menggunakan jenis penelitian deskriptif kuantitatif dengan pendekatan Cross-sectional study. Hasil penelitian menunjukkan bahwa faktor-faktor yang berpengaruh terhadap ketidakpatuhan pengobatan pasien kusta di Puskesmas Kassi-Kassi dan Puskesmas Tamalate meliputi tingkat pengetahuan pasien, dukungan keluarga, dan ketersediaan obat. Sebaliknya, faktor tipe kusta, efek samping obat, dan kondisi ekonomi tidak memiliki pengaruh signifikan terhadap ketidakpatuhan pengobatan. Dari total 31 pasien yang diteliti, mayoritas pasien berjenis kelamin laki-laki (16 orang), berusia 26-50 tahun (13 orang), dan dengan tipe kusta Multi Basiler (MB) sebanyak 18 orang. Temuan ini menegaskan pentingnya edukasi yang memadai, penguatan dukungan keluarga, dan peningkatan ketersediaan obat untuk meningkatkan kepatuhan pasien dalam menjalani pengobatan kusta.
Case Report: Second-Degree Burns due to Hot Liquid Asphalt Cement Spillage in an Adult Patient with Comorbid Diabetes Mellitus Maha Umami Putri Qulzum; Sri Vitayani; Widjoyo
The International Journal of Medical Science and Health Research Vol. 13 No. 5 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/6s9s0873

Abstract

Burns represent a significant form of injury that leads to substantial tissue damage, necessitating complex management strategies tailored to the degree and total body surface area (TBSA) affected. The complexity of burn management is notably increased in patients with comorbidities such as diabetes mellitus. Diabetes mellitus can induce vascular disorders and peripheral neuropathy, which collectively impair the natural wound healing process. This report details the case of a 42-year-old male who presented to the Emergency Department of Makassar City Hospital with burns on his right and left legs. The injuries were sustained approximately 30 minutes prior from a spill of hot liquid asphalt cement at his workplace and were accompanied by a significant burning sensation. The patient, weighing 58 kg, reported no fever, headache, dyspnea, nausea, or vomiting, with normal bowel and bladder function. He had no history of similar injuries, allergies, or hypertension. However, he had a known history of diabetes mellitus, which was managed with metformin 500 mg three times daily. A family history of diabetes was present on his maternal side. Burns, or combustio, are defined as tissue damage or loss resulting from contact with thermal sources like fire and hot water, or with chemicals, electricity, and radiation. Hot water and flames are the most frequent causes of burns. The primary principle of first aid is to halt the burning process and reduce the wound's temperature. For flame-related burns, this involves the "Stop, Drop, Cover (Face) & Roll" technique.
Literature Review: The Relationship Between The Incidence Of Infection And Length Of Stay In Burn Patients Siti Aisyah Karina HB; Sri Vitayani; Syakir
The International Journal of Medical Science and Health Research Vol. 14 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/kc7qpt84

Abstract

Burn injuries are a global health issue that cause high morbidity and mortality, particularly in low- to middle-income countries such as Indonesia. Infection is the most common complication that prolongs hospitalization and increases the risk of death in burn patients. The aim of this study is to review the relationship between infection incidence and the length of hospital stay in burn patients based on national and international literature. Based on the review of 10 articles, it was found that infections caused by resistant pathogenic bacteria such as  Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus significantly extend the duration of treatment. Other risk factors, including the extent of the burn, delayed treatment, and immune response, also affect the length of hospitalization. Proper and early management—including wound care, antimicrobial therapy, and community education—is crucial for accelerating the healing
Prevalensi Lepra Tahun 2019 – 2024 di Rumah Sakit Lukman, Moudyana; Vitayani, Sri; Frisa, Selis
Jurnal Ilmiah Global Education Vol. 6 No. 3 (2025): JURNAL ILMIAH GLOBAL EDUCATION
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/jige.v6i3.4048

Abstract

Leprosy or Morbus Hansen is a chronic infectious disease with prominent involvement of the skin and nerves caused by the bacillus Mycobacterium leprae. Leprosy is divided into two main forms depending on the degree and type of immunity. Lepromatous lessing with a dominant Th2 response and tuberculoid with a dominant Th1 response. Early diagnosis and rapid treatment of all new cases of leprosy treated with multidrug (MDT) is a recommendation from the World Health Organization (WHO) is still a key strategy in controlling leprosy and further preventing nerve damage and disability. Objective: This report aims to know the prevalence of leprosy in 2019 - 2024 in Hospitals. Method: The method used is a literature review with a Narrative Review design. Results: The results obtained in this literature are 15 articles obtained with arrangement from 2020 - 2025 and an in-depth analysis of the strengths and weakness of each article has been carried out regarding the prevalence of leprosy in 2019 - 2024 in Hospitals, 15 articles mention the prevalence of leprosy in 2019 - 2024 in Hospitals. The most dominant characteristics of Hansen's disease in this literature review are age and type of Hansen's disease, followed by gender. Although there are several other characteristics such as occupation.
Hubungan Kejadian Melasma terhadap Paparan Sinar Ultraviolet (UV) pada Pekerja Luar Ruangan di Pasar Induk Minasa Maupa Fadhilah, Andi Sausan; Vitayani, Sri; Namirah, Hanna Aulia; Yuniati, Lisa; Rasfayanah, Rasfayanah
Syifa'Medika Vol 16, No 1 (2025): Syifa Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v16i1.9727

Abstract

Melasma is a common hyperpigmentation disorder that typically appears on sun-exposed areas of the face and is often associated with Ultraviolet (UV) exposure and hormonal factors. This study aimed to examine the relationship between UV exposure and melasma incidence among outdoor workers at Minasa Maupa Central Market, considering hormonal contraceptive use as a confounding factor. A cross-sectional design was used, involving 32 female respondents selected through purposive sampling. Data were collected via observation and validated questionnaires, then analyzed using univariate and bivariate Chi-Square tests. Results indicated a significant relationship between prolonged UV exposure (?4 hours) and melasma occurrence (p=0.022), as well as between hormonal contraceptive use and melasma (p=0.028). However, no significant interaction was found between UV exposure duration and contraceptive use (p=0.849). These findings highlight that UV exposure and hormonal contraceptive use independently contribute to melasma risk. Skin protection education and medical monitoring for contraceptive users are recommended preventive strategies. Future research using longitudinal design and direct UV intensity measurement is suggested to enhance understanding and accuracy.
ANALISIS HUBUNGAN FAKTOR RISIKO DENGAN KEJADIAN KEMATIAN DALAM RAHIM (KJDR) DI RSIA ST KHADIJAH I MAKASSARTAHUN 2018 Asra, Nurhuda; Vitayani, Sri; Habo, Hasriwiani
Diagnosis Jurnal Ilmiah Kesehatan Vol. 13 No. 5 (2018): Diagnosis: Jurnal Ilmiah Kesehatan
Publisher : STIKES Nani Hasanuddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Intrauterine Fetal Death/Kematian Janin Dalam Rahim merupakan kematian perinatal.Menurut WHO dan The American College of Obsetricians and Gynecologist Kematian Janin Dalam Rahim adalah janin yang mati dalam rahim dengan berat 500 gram atau lebih atau kematian janin dalam Rahim setelah 20 minggu kehamilan. Indonesia merupakan salah satu negara dengan Angka Kematian Bayi (AKB) yang cukup tinggi yaitu 25,5% pada tahun 2016. Tujuan penelitian ini adalah untuk mengetahui hubungan umur dan preeklamsia pada ibu dengan kejadian KJDR di RSIA Sitti Khadijah I. Penelitian ini merupakan jenis penelitian observasional dengan pendekatan cross sectional. Pengambilan sampel pada penelitian ini dilakukan dengan tenik purposive sampling dan jumlah sampel sebanyak 150 orang. Instrumen yang digunakan adalah data rekam medik di RSIA Sitti Khadijah 1. Data dianalisis menggunakan program SPSS dengan uji stastistik Chi-Square dan tingkat kemaknaan ρ Value < 0,05. Berdasarkan hasil analisis hubungan antara umur ibu dengan kejadian KJDR diperoleh nilai ρ= 0,000 berarti ada hubungan bermakna antara umur ibu dengan kejadian KJDR. Sedangkan hubungan antara preeklamsia pada ibu dengan kejadian KJDR diperoleh nilai ρ= 0,003 berarti ada hubungan antara preeklamsia pada ibu dengan kejadian KJDR. Kesimpulan dalam penelitian ini adalah terdapat hubungan umur ibu dan preeklamsia pada ibu dengan kejadian KJDR di RSIA Sitti Khadijah I Makassar. Diharapkan ibu hamil untuk melakukan pemeriksaan kehamilan minimal 4 kali selama hamil atau segera setelah mendapati tanda bahaya dalam kehamilan agar segera mendapatkan penanganan bila terjadi komplikasi.
Co-Authors A. Nadia sulistia ningsih Abbas, Hasriwiyani Habo Abrar, Muhammad Edwin Raihan Adharia, Adharia Agung, Muh Rafly Ali, Yaumil Mutmainnah Ameliah, Nabila Andi Masdipa Anwar, Mentari Maqfira Aprilia, Salsabila Tirta Arnie Isnaini Arfah Asra, Nurhuda Aulia, Aulia Bamahry, Aryanti Berry Erida Hasbi Dahlia Dahliah Dahliah, Dahliah Darma, Sidrah Daud, Nur Ramahdani Dian Amelia Abdi Dian Febriyanti Nur Fadhilah, Andi Sausan Floria Eva, Floria Frisa, Selis Galagher, Mahry Gani, Azis Beru Habo, Hasriwiani Habo, Hsriwiani Hadi, Santriani Handayani, Dewi Sri Harahap, Muhammad Wirawan Irmayanti Irmayanti, Irmayanti Iskandar, Darariani Ismail, Mardhiyah Adawiyah Jaya, Muhammad Alim Karim, Marzelina Khaeruddin HA Khairuddin Djawad Khomeny, Imran Al Mu’min Lukman, Moudyana Maha Umami Putri Qulzum Mahfud, Multazam Pratama Makmun, Armanto Marzelina Karim Mohammad Reza Zainal Abidin Muh. Nasrum Massi Muhammad Syabilal Alfat Al Buyani Munsir Ahyar Namirah, Hanna Aulia Nasruddin, Hermiaty Nasrudin Andi Mappaware natasya widiyana putri Nelcy, Yuliana Nevi sulvita karsa Nilam, Nilam Nita Ramdhani Nur Aulia Nur Aulia Amir Nur, Muh Jabal Nurelly Noro Waspodo, Nurelly Noro Nurmadilla, Nesyana Pramono, Sigit Dwi Purnama, Indah Dian Rachmat Faisal Syamsu Rasfayanah, Rasfayanah Ratih Natasha Samosir, Abdi Dwiyanto Putra Sanusi, Mayamariska Shulhana Mokhtar Siti Aisyah Karina HB Solecha setiawati Sri Wahyu Syakir Syamsu Rijal Syamsu Rijal Syarifuddin Rauf Widjoyo Wiriansya, Edward Pandu Yuniarti, Lisa Yuniati, Lisa Yusriani Mangarengi