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Journal : Science and Technology Indonesia

A Cytotoxic Activity of Tahongai (Kleinhovia hospita Linn.) Leaves Extracts Using Brine Shrimp Lethality Test Solihah, Indah; Herlina, Herlina; Rasyid, Riana Sari Puspita; Suciati, Tri; Khairunnisa, Khairunnisa
Science and Technology Indonesia Vol 4 No 3 (2019): July
Publisher : ARTS Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1489.712 KB) | DOI: 10.26554/sti.2019.4.3.60-63

Abstract

Tahongai (Kleinhovia hospita Linn.) leaves had been known contain alkaloids, flavonoids, saponins, steroids, and tannins. At Komering, South Sumatera tribe, tahongai leaves had been known to treat tumor, cancer, polyps, acne, and dysmenorrhea. The study of cytotoxic activity of tahongai bark and stem were done. This study aims to determine the cytotoxic activity of tahongai leaves extracts using BSLT method. Tahongai leaves were extracted using gradual maceration with n-hexane, ethyl acetate, and ethanol 96%. Each extract was tested cytotoxic activity towards Artemia salina L. larvae. The yield of n-hexane, ethyl acetate, and ethanol extracts are 2,686%, 7,033%, and 7,933% respectively. Ethanol extract of tahongai leaves had the best cytotoxic activity with lethality value 76,667% at 500ppm. Statistical analysis with two way ANOVA showed extract and concentration had a significant (p<0,05) effect on larvae lethality percentage.
Synthesis of a 3D Porous Multicomponent Bioceramic Scaffold Sari, Yessie Widya; Munir, Ryaas Mishbachul; Saputra, Angga; Sari, Mona; Aminatun; Suciati, Tri; Mohamad, Che Wan Sharifah Robiah; Gunawarman; Yusuf, Yusril
Science and Technology Indonesia Vol. 9 No. 2 (2024): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.2.235-243

Abstract

In this study, 3D porous multicomponent bioceramic scaffolds were fabricated. Hydroxyapatite (HA) and carbonate-substituted hydroxyapatite (CHA) synthesized from Asian moon scallop shell (Amusium pleuronectes) served as the bioceramics, whereas alginate and chitosan served as the polymeric components. The study was focused on determining whether the presence of polyvinyl alcohol (PVA) in the scaffold exerted an impact. When PVA was not included, the morphological examination revealed that the samples exhibited porous structures characterized by effective pore interconnectivity and a substantial pore size. X-ray diffraction and scanning electron microscopic analyses indicated that the inclusion of PVA led to a decrease in the crystallinity, pore size, and porosity of the scaffolds. Those containing PVA exhibited porosity levels in the range of 56%–60%, and pore sizes ranged from 42 to 90 µm. These properties may provide advantages for the scaffold with respect to the ability for cell migration and cell attachment, thus enhancing new bone formation. Moreover, the compositions of HA and chemically modified HA (CHA) within the scaffold influenced the crystallinity and uniformity of the scaffold morphology. This finding suggests the potential for crafting a customized porous bioceramic scaffold based on specific compositions.
Co-Authors Adipputra, Ricky Fajar Adnindya, Msy Rulan AE. Sukmawati AE. Sukmawati, AE. Afifah, Ervi Aminatun Ana Indrayati Angga Saputra Ardesy Melizah Kurniati Arinta, Yukko Benny Permana Cita, Juang Arwafa Dalilah Dalilah Darijanto, Sasanti Tarini DEBBIE SOEFIE RETNONINGRUM Dwi Ratnaningsih, Dwi Dwiani, R. R. Sarlita Elin Julianti Ella Amalia, Ella Fauziah, Arsy Fertilita, Soilia Fith Khaira Nursal Fitrianti Fitrianti, Fitrianti Gita Dwi Prasasty Gunawarman Gusdinar, Tutus Hasbi, Alfian HENI RACHMAWATI Herlina Herlina Ilyah Abdullah, Nour Indri Seta Septadina Irda Fidrianny Iwo, Maria Immaculata Januar, M. Anis Jo Suherman Julianti, Elin Karim, Fatmawati Khairunnisa Khairunnisa Larasati, Veny Legiran Legiran Lili Fitriani Lisa Patricia Lusiana Darsono Mahardika Putri, Sima Asmara Dewa Marya Malahayati, Putri Maria Immaculata Iwo Maria Immaculata Iwo Marlia Singgih Marlia Singgih Marlia Singgih Wibowo Mohamad, Che Wan Sharifah Robiah Muhammad Farhan Muhammad, Fadhil Munir, Ryaas Mishbachul Niknik Widanengsih Nirwan Syarif, Nirwan Nugraha, Yuda Prasetya Nurani Istiqomah Odiesta, Muhammad Ramadhan Patricia, Lisa Prasetya, Dinda Prihantini, Malinda Rahmana Emran Kartasasmita Rahmatullah, Nurul Ilmi Rahmatullah, Nurul Ilmi Rasyid, Riana Sari Puspita Resmiyani, Ubbadah Riani, Catur Rizal Rizal Sani Ega Priani Sari, Mona Sasanti Tarini Darijanto Sasanti Tarini Darijanto, Sasanti Tarini Satrialdi, - Satrialdi, Satrialdi Sima Asmara Dewa Marya Mahardika Putri Solihah, Indah Sri Priatni Sri Priatni Sudiati, Titi Sujilah, Ajeng Rana Wulan Sukmadaja Asyarie Sumirtapura, Yeyet Cahyati Susanto, Eriwan Syarifah Aini Syauki Ikhsan, Diyaz T. Gusdinar T. Gusdinar, T. Titah Yudistira Tjandrawati Mozef Tutus Gusdinar WAHYU WIDOWATI Wardiansah Wardiansah, Wardiansah Widanengsih, Niknik Yani Triyani Yessie Widya Sari Yusril Yusuf