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All Journal BIOTROPIA - The Southeast Asian Journal of Tropical Biology Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Matematika & Sains Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Acta Pharmaceutica Indonesia JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Science and Technology Indonesia Jurnal Penelitian Sains JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Farmasi Indonesia SRIWIJAYA JOURNAL OF MEDICINE Jurnal Ilmu Kefarmasian Indonesia Majalah Kesehatan Indonesia Jurnal Pengabdian Masyarakat: Humanity and Medicine Journal of Community Development Jurnal Permata Indonesia Pangripta Jurnal Ilmiah Kajian Perencanaan Pembangunan Jurnal Manusia dan Lingkungan
Tri Suciati
Sekolah farmasi - ITB, Jl. Ganesha 10 Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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RULA-Based Ergonomic Assessment of Sitting Posture as a Risk Factor for Neck Pain in Students Septadina, Indri Seta; Wardiansah; Suciati, Tri; Adnindya, Msy Rulan; Putri, Sima Asmara Dewa Marya Mahardika; Legiran; Malahayati, Putri; Odiesta, Muhammad Ramadhan; Hasbi, Alfian
Majalah Kesehatan Indonesia Vol. 6 No. 4 (2025)
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/makein.2025294

Abstract

Research on ergonomic risk factors for neck pain among Islamic boarding school students remains scarce, despite their prolonged study and Qur’an memorization activities in static sitting postures. Non-neutral body posture during learning may increase the risk of musculoskeletal disorders (MSDs), particularly neck pain, which can impair concentration and quality of life. This analytic cross-sectional study aimed to assess students’ body posture during study and memorization activities and to examine its association with neck pain. A total of 72 boarding and non-boarding students participated. Data were collected using questionnaires and the Rapid Upper Limb Assessment (RULA), and analyzed with chi-square tests and logistic regression to obtain prevalence ratios (PR) and p-values. Neck pain was reported by 63.9% of respondents; 72.2% exhibited poor sitting posture, and 80.6% reported moderate-to-severe stress. Bivariate analysis showed a significant association between stress level and neck pain (p = 0.033; PR = 2.19; 95% CI: 1.25–3.83). In multivariate logistic regression, no variable reached conventional statistical significance; however, students with moderate-to-severe stress had a 3.81-fold higher risk of neck pain (p = 0.057). These findings underscore the need for integrated ergonomic and psychosocial interventions in Islamic boarding school settings to reduce neck pain risk among students.
Regulation of Adipogenesis and Key Adipogenic Gene Expression by Mangosteen Pericarp Extract and Xanthones in 3T3-L1 Cells Widowati, Wahyu; Darsono, Lusiana; Suherman, Jo; Afifah, Ervi; Rizal, Rizal; Arinta, Yukko; Mozef, Tjandrawati; Suciati, Tri
BIOTROPIA Vol. 27 No. 1 (2020): BIOTROPIA Vol. 27 No. 1 April 2020
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.545 KB) | DOI: 10.11598/btb.2020.27.1.932

Abstract

Obesity is one of the risk factors for atherosclerosis, and its occurrence and development are associated with fat accumulation and adipocyte differentiation. Thus, the suppression of adipocyte differentiation can be a potential anti-obesity approach. This study examined the effect of mangosteen pericarp extract (MPE) and xanthones (α-Mangostin (AM) and γ-Mangostin (GM)) on the expression of PPARγ, C/EBPα, SCD1, LPL, aP2, adipoQ, and FAS in 3T3-L1 cells. Concentrations of MPE and xanthones used were based on cytotoxicity assays on 3T3-L1 cells. Three different MPE concentrations (0, 25, and 50 µg/mL), three AM concentrations (0, 25, and 50 µM), and GM concentrations (0, 50, and 75 µM) were used. The expressions of PPARγ, C/EBPα, SCD1, LPL, aP2, adipoQ, and FAS genes were measured using real-time quantitative PCR. Gene expression was downregulated in cells treated with 50 µg/mL MPE and 50 µM GM. However, 25 µM and 50 µM AM did not suppress PPARγ and SCD1 expression. The 50 µM AM treatment also failed to reduce aP2 gene expression. Overall, MPE and GM demonstrated potential anti-adipogenesis and anti-obesity effects by suppressing the expression of PPARγ, C/EBPα, SCD1, LPL, aP2, adipoQ, and FAS in 3T3-L1 cells.
Co-Authors Adipputra, Ricky Fajar Adnindya, Msy Rulan AE. Sukmawati AE. Sukmawati, AE. Afifah, Ervi Aminatun Ana Indrayati Angga Saputra Ardesy Melizah Kurniati Arinta, Yukko Benny Permana Cita, Juang Arwafa Dalilah Dalilah Darijanto, Sasanti Tarini DEBBIE SOEFIE RETNONINGRUM Dwi Ratnaningsih, Dwi Dwiani, R. R. Sarlita Elin Julianti Ella Amalia, Ella Fauziah, Arsy Fith Khaira Nursal Fitrianti Fitrianti, Fitrianti Gita Dwi Prasasty Gunawarman Gusdinar, Tutus Hasbi, Alfian HENI RACHMAWATI Herlina Herlina Ilyah Abdullah, Nour Indri Seta Septadina Irda Fidrianny Iwo, Maria Immaculata Januar, M. Anis Jo Suherman Julianti, Elin Karim, Fatmawati Khairunnisa Khairunnisa Legiran Legiran Lili Fitriani Lisa Patricia Lusiana Darsono Mahardika Putri, Sima Asmara Dewa Marya Malahayati, Putri Maria Immaculata Iwo Maria Immaculata Iwo Marlia Singgih Marlia Singgih Marlia Singgih Wibowo Mohamad, Che Wan Sharifah Robiah Muhammad, Fadhil Munir, Ryaas Mishbachul Niknik Widanengsih Nirwan Syarif, Nirwan Nugraha, Yuda Prasetya Nurani Istiqomah Odiesta, Muhammad Ramadhan Patricia, Lisa Prasetya, Dinda Prihantini, Malinda Rahmana Emran Kartasasmita Rahmatullah, Nurul Ilmi Rahmatullah, Nurul Ilmi Rasyid, Riana Sari Puspita Resmiyani, Ubbadah Riani, Catur Rizal Rizal Sani Ega Priani Sari, Mona Sasanti Tarini Darijanto Sasanti Tarini Darijanto, Sasanti Tarini Satrialdi, - Satrialdi, Satrialdi Sima Asmara Dewa Marya Mahardika Putri Solihah, Indah Sri Priatni Sri Priatni Sudiati, Titi Sujilah, Ajeng Rana Wulan Sukmadaja Asyarie Sumirtapura, Yeyet Cahyati Susanto, Eriwan Syarifah Aini Syauki Ikhsan, Diyaz T. Gusdinar T. Gusdinar, T. Titah Yudistira Tjandrawati Mozef Tutus Gusdinar WAHYU WIDOWATI Wardiansah Wardiansah, Wardiansah Widanengsih, Niknik Yani Triyani Yessie Widya Sari Yusril Yusuf