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Rekomendasi Apoteker Pada Pasien Diabetes Melitus Tipe II Dengan Komplikasi Nefropati Berdasar Analisis Drug Related Problems (DRP) (Studi Kasus di Instalasi Rawat Inap RSUD Karawang) Faridah Syamsiah; Yusi Anggriani; Hesty Utami Ramadaniati; Hidayat Hidayat
Innovative: Journal Of Social Science Research Vol. 3 No. 4 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i4.4178

Abstract

Penelitian ini dilakukan untuk mengkaji profil rekomendasi Apoteker atas DRP pada pasien penyakit DM nefropati serta faktor-faktor yang mempengaruhi respons dokter terhadap rekomendasi yang disampaikan oleh Apoteker. Penelitian ini bersifat observasional dengan desain prospective case series. Subyek penelitian ini adalah seluruh pasien penyakit DM nefropati rawat inap di Instalasi Rawat Inap RSUD Karawang selama September – Desember 2022 yang memenuhi kriteria inklusi dan eksklusi penelitian. Dalam penelitian ini, DRP diklasifikasikan berdasarkan sistem klasifikasi PCNE V9.0. Hasil penelitian menunjukkan bahwa dari 85 DRP yang didentifikasi, terdapat 247 rekomendasi. Rekomendasi pada tataran penulis resep sebanyak 65,18%, pada tataran obat sebanyak 34,82%. Sebanyak 64,37% dari 247 rekomendasi yang diberikan pada tataran penulis resep tidak disetujui dan 35,63% rekomendasi disetujui.
BIAYA MEDIS LANGSUNG PASIEN HEMODIALISIS DI RUMAH SAKIT UMUM DAERAH (RSUD) ARJAWINANGUN DAN RSUD WALED KABUPATEN CIREBON Dosi Ahmad Yani; Prih Sarnianto; Yusi Anggriani
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 4 No 1 (2019)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v4i1.123

Abstract

Penyakit Ginjal Kronis (PGK) merupakan masalah kesehatan global dengan biaya tinggi. Terapi Pengganti Ginjal (TPG) yang paling sering dilakukan yaitu hemodialisis (HD). Saat ini sebagian besar pasien PGK yang melakukan HD dijamin pembiayaannya oleh Badan Penyelengara Jaminan Sosial Kesehatan (BPJS-K) dengan besaran jaminan sesuai tarif Indonesian Case-Base Groups (Ina-CBGs) yang pernah mengalami penurunan pada tahun 2016. Penelitian ini bertujuan untuk mendeskripskan biaya medis langsung pasien yang menjalani hemodialisis untuk mengetahui rata-rata biaya pelayanan selama satu tahun (real cost), mengetahui besaran biaya apabila pelayanan diberikan sesuai standar pelayanan menurut Perhimpunan Nefrologi Indonesia, PERNEFRI (ideal cost) serta membandingkan ideal cost dengan tarif Ina-CBGs untuk RS pemerintah tipe B. Penelitian ini merupakan penelitian deskriptif dari sudut pandang pemberi pelayanan (Rumah Sakit) pada pasien yang memenuhi kriteria inklusi. Data biaya diambil dari Sistem Informasi Manajemen Rumah Sakit (SIMRS) dan data klaim InaCBGs. Analisis data dilakukan untuk melihat rata-rata biaya medik langsung dan membandingkannya dengan biaya untuk pelayanan ideal. Dari 93 pasien yang dianalisis, 51,6% berjenis kelamin laki-laki, usia rata-rata (minimal-maksimal) 48 (20-75) tahun, 86% menikah, pendidikan sekolah dasar atau dibawahnya 49,5%. Biaya medis langsung Rp. 791.967; 9,9% lebih kecil dari biaya klaim InaCBGs. Namun biaya ideal HD rata-rata Rp 958.467; 8,7% lebih besar dari biaya klaim InaCBGs. Kesimpulan penlitian adalah biaya InaCBGs HD masih lebih besar dari real cost, namun lebih kecil dari ideal cost.
COST-EFFECTIVENESS ANALYSIS OF ANTICOAGULANT USAGE IN COVID-19 PATIENTS AT 45 KUNINGAN HOSPITAL Juju Jumiati; Yusi Anggriani; Yati Sumiyati; Umar Santosa
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 4 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i4.892

Abstract

Cost-effectiveness analysis (CEA) is a pharmacoeconomic method that compares prices from all sources consumed (cost) with the outcome value of a program or intervention to obtain objective answers to the selection of drugs that are effective in terms of benefits and costs. COVID-19, or Coronavirus Disease 2019, is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2) and causes acute respiratory distress, including fever, coughing, and shortness of breath. Fondaparinux, aside from heparin and enoxaparin, can be given as an anticoagulant therapeutic option in hospitalized COVID-19 patients, according to the third edition of the COVID-19 care recommendations. This study aimed to find the most cost-effective therapy among heparin, enoxaparin, and fondaparinux in COVID-19 patients at the RSUD’45 Kuningan. It also applied descriptive non-experimental research methods with retrospectively collected data. The intervention that had been studied was the administration of anticoagulant medication, where the effectiveness of the drug was observed in the reduction of D-dimer levels to normal levels. Meanwhile, the costs were observed from the perspective of a healthcare provider, specifically the RSUD’45 Kuningan. The study sample included 107 patients, with 13 receiving heparin, 41 receiving enoxaparin, and 53 receiving fondaparinux. Bivariate analysis using the chi-square test revealed no significant difference between the drug groups in the proportion of patients who improved and did not improve (sig. value = 0.610)...
PENGARUH PELAYANAN HOME CARE APOTEKER PADA PENGETAHUAN, KEPATUHAN, KUALITAS HIDUP, DAN OUTCOME KLINIS PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS KOTA TANGERANG Irna Fitriana; Hesty Utami R; Yusi Anggriani; Yuliani
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1556

Abstract

Pelayanan kefarmasian yang berfokus pada pasien, khususnya home pharmacy care, menekankan penerapan edukasi melalui home care oleh apoteker sebagai pendekatan untuk memodifikasi perilaku hidup pasien. Penelitian ini bertujuan untuk menginvestigasi dampak pelayanan home care apoteker terhadap pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis pada pasien diabetes melitus tipe 2. Penelitian dilaksanakan di Puskesmas Neglasari (kelompok intervensi) dan Puskesmas Bugel (kelompok kontrol) selama periode tiga bulan dengan desain quasi eksperimental menggunakan two group pretest-posttest. Sampel penelitian dipilih melalui metode total sampling, melibatkan 100 pasien diabetes melitus tipe 2 (51 dalam kelompok intervensi dan 49 dalam kelompok kontrol). Instrumen penelitian berupa Kuesioner ADL knowledge, kuesioner Medication Adherence Report Scale (MARS) dan Kuesioner Short form-36 (SF-36). Pada tahap awal penelitian, uji Chi-Square menunjukkan bahwa tidak ada perbedaan signifikan dalam karakteristik demografi dan profil klinis antara kedua kelompok, dengan nilai p p-value >0,005. Setelah intervensi home care, uji Chi-Square pada kelompok intervensi mengindikasikan perubahan yang signifikan sebelum dan sesudah pemberian home care terkait pengetahuan (p=0,000), tingkat pengetahuan menggunakan dua metode MARS-5 (p=0,003) dan pill count (p=0,005), kualitas hidup (p=0,000), serta hasil klinis (p=0,013). Sementara pada kelompok kontrol, tidak terdapat perbedaan yang signifikan sebelum dan sesudah penelitian, dengan nilai p-value >0,005. Uji Mann-Whitney menunjukkan perbedaan signifikan pada hasil posttest terkait pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis antara kedua kelompok (p=0,000*). Uji korelasi dengan Spearman’s rho menegaskan adanya hubungan antara pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis (sig=0,000). Kesimpulan dari penelitian ini adalah bahwa pelayanan home care yang disediakan oleh apoteker efektif dalam memperbaiki seluruh aspek variabel yang menjadi fokus penelitian.
Analysis of Medication, Cost, and Clinical Outcome of Human and Analogue Insulins of Type 2 Diabetes Mellitus at MMC Hospital 2016-2017 Jayati, Turpuk Mannaria; Anggriani, Yusi; Laksmitawati, Dian Ratih; Waspadji, Sarwono
Health Information : Jurnal Penelitian Vol 13 No 2 (2021): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v13i2.273

Abstract

Human insulin and analog insulin are available at RS.MMC. The use of analog insulin was more prevalent among doctors between 2016 and 2017. The data collection was conducted retrospectively, taking samples of 132 outpatients type 2 DM using insulin, of which 74 were evaluated for their clinical outcome. The study's goal is to provide information for developing insulin usage guidelines. The medication profile data were collected from the medicine administration at the Hospital Pharmacy Installation. The clinical outcome data, such as fasting plasma glucose (FPG), two-hour postprandial plasma glucose (2HPP), and Hemoglobin A1c (HbA1c), were garnered from the patients’ medical records. The cost data were collected from the outpatients’ payment receipts provided by the Hospital’s Financial Department. Kolmogorov Smirnov normality test was applied in this research. Statistical trials of differences in clinical outcomes and costs using the Kruskal-Wallis test, showed there was a significant difference between human insulin and insulin analogues in terms of clinical outcomes of GDP, GDPP, HbA1c, and cost after follow-up testing with Mann Whitney, showed average cost of using human insulin for 30 days was Rp1,597,066, and analogue was Rp2,497,535 shows that human insulin and analogues differ significantly in terms of cost (p = 0.015).
Faktor Yang Berhubungan Dengan Kepatuhan Minum Obat Pada Penderita Skizofrenia Fase Stabil Di Poli Rawat Jalan RS Jiwa Daerah Provinsi Lampung Tahun 2022 Harissa, Nola; Anggriani, Yusi; Sarnianto, Prih; Septa, Tendry
JFL : Jurnal Farmasi Lampung Vol. 12 No. 2 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i2.1110

Abstract

Adherence with antipsychotic treatment is very important to achieve optimal therapeutic results to the people with schizophrenia. The aim of the study is to determine the factors associated with medication adherence in patients with stable phase of paranoid schizophrenia at the Outpatient Polyclinic of the Regional Hospital of Lampung Province in 2022. This study used a crosssectional method with prospective data collection, a sample of 176 and the use of purposive sampling for the sampling technique. The data obtained were analyzed by using the chi square test to find out the relation between the dependent variable which is medication adherence, and the independent variables, namely perceptions of family support, knowledge related to disease, perceptions of drug side effects, and the perceptions of the pharmacist's role. To find out the dominant factors influencing the medicine compliance, the data were analyzed by using ordinal logistic regression. The study obtained of medicine compliance rates in paranoid schizophrenia patients based on the MMAS scale were good in 53 (30.1%), moderate in 62 (35.2%) and poor in 61 (34.7%). There is a relationship between medication adherence and the perception of family support (p value 0.038), knowledge related to disease (p value 0.005), perception of drug side effects (p value 0.003), and perception of the role of pharmacist (p value 0.000). The dominant factor affecting compliance to taking medication is the perception of the pharmacist's role with OR = 2.8, which means patients who get a good pharmacist role are more compliant in taking medication by 2.8 times. Keywords: Medication Compliance, Paranoid Schizophrenia, Stable Phase, Outpatient
Analisis Biaya Operasi Teknik Off-pump CABG dibandingkan On-pump CABG Pasien BPJS Penyakit Jantung Koroner dengan Fungsi Jantung Buruk di Rumah Sakit Jantung Harapan Kita Aris Aris; Yusi Anggriani; Hanafy Dudy Arman; Yacob Ruru
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.440

Abstract

Coronary heart disease (CHD) is a heart disease that is mainly caused by narrowing of the coronary arteries due to atherosclerosis or spam or a combination of both. In CHD patients who continued therapy, coronary artery bypass surgery can be performed Off-pump CABG or On-pump CABG, with hearts function poorly with LEF < 30 % at risk and a higher complication which results in increased costs. The research is aimed to analyze the operating cost Off-pump CABG technique compared to the On-pump CABG technique in patients with BPJS coronary heart disease with poor heart function in Rumah Sakit Jantung dan Pembuluh Darah Harapan Kita on period January – December 2015. Patient sample selection is done in the installation of medical records with the diagnosis of CHD undergoing coronary artery bypass surgery technique Off-pump CABG and On-pump CABG. Data retrieval costs of pre-operatives, peri-operatives, and post-operative. This research conducted prospectively. Data were analyzed using the Kolmogorov test, Mann Whitney test, and Kruskal Wallis test. Research results obtained from a total of 70 patients with each of the 35 patients who underwent Off-pump CABG and On-pump CABG. The average cost of technique operation Off-pump CABG amounted to Rp.85,812,864. The average cost of technique operation on-pump CABG amounted to Rp.105,480,363. Operation margin amounted to Rp. 19,667,499. Mann-Whitney test shows different averages with p-value=0,006, then there is a significant difference between the two groups. Comparison of the rates for the Ina-CBGs surgery techniques Off-pump CABG an average of Rp.141,747,683, different of Rp. 55,934,819. Of the rates for the Ina-CBGs surgery techniques on-pump CABG an average of Rp. 138,782,251, different of Rp. 33,301,888. Kruskal Wallis test shows a different averages with p-value=0,000, then there is a significant difference between the two groups. Operating cost Off-pump CABG technique is lower than of On-pump CABG surgery technique. Operating cost Off-pump CABG technique and On-pump CABG lower than tariff Ina-CBGs.
Analysis Of The Effectiveness Of LMWH Compared To UFH In COVID-19 Patients With Coagulation Disorders At Pasar Minggu Regional General Hospital Edwina Dharmawati; Yusi Anggriani; Muhammad Reza
Jurnal Ekonomi Vol. 13 No. 04 (2024): Edition October -December 2024
Publisher : SEAN Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: COVID-19 disease causes multiorgan damage and impacts the cardiovascular system. The Increase in death cases occurs due to coagulation disorders characterized by increased d-dimer parameters, bleeding, thrombocytopenia, and thrombosis. Objective: To analyze the effectiveness of the use of LMWH anticoagulants compared to UFH in COVID-19 patients with coagulation disorders in hospital. Methods: Observational retrospective data collected1with cross sectional design. Methods of collecting data on COVID-19 inpatients in the January-December 2021 period based on moderate, severe, and critical severity of the disease. The data used is medical record data and analysis using chi square. Results: The sample consisted of 6362patients who met the inclusion criteria with the largest difference in decrease D-dimer values in critical severity for LMWH (4.8 ug/ml) and UFH (4.0 ug/ml). Wilcoxon test analysis *showed that there was a significant difference between the use of LMWH and UFH based on the decrease in D-dimer values.
Evaluasi Penggunaan Insulin pada Pasien Diabetes Melitus Tipe 2 Rawat Jalan di Rumah Sakit X di Jakarta Periode 2016-2017 Anggriani, Yusi; Rianti, Alfina; Pratiwi, Annisa Nadya; Puspitasari, Wulan
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 1 (2020): J Sains Farm Klin 7(1), April 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.1.52-59.2020

Abstract

Type 2 Diabetes Mellitus (DMT2) is a metabolic disease with the characteristics of hyperglycemia that occurs due to abnormal insulin secretion. One of the treatments of DM is insulin therapy. Based on its provenance, insulin consists of human insulin and analogue insulin. This study was conducted to identify profiles of insulin used in DMT2 patients at RSUP X hospital in Jakarta. This was an observational study conducted retrospectively on data from 2016 to 2017. The total sample numbers of DMT2 outpatients using insulin were 218 in 2016, and 225 in 2017. Data on insulin therapy regimens were obtained from medical records and drug use reports. The results obtained from this study indicated that the type of insulin that was widely used by DMT2 outpatients was analogue insulin with a percentage of 99%. The human insulin was rarely used in outpatients. The highest use of analogue insulin was analog premixed insulin (35%).
Survei Rumah Tangga terhadap Profil Obat pada Responden dengan Jaminan Kesehatan Nasional di Jakarta Timur Restinia, Mita; Anggriani, Yusi; Khairani, Sondang; Wijaya, Rulliani Bianca
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 2 (2020): J Sains Farm Klin 7(2), Agustus 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.2.158-163.2020

Abstract

Household surveys are one of the methods to obtain accurate information on medicine utilization in society. The study was carried out to identify the access of medicine and medicine utilization profile. A survey using convenient sampling method was conducted in 30 households with national health insurance (JKN) diagnosed with chronic diseases in East Jakarta. Each family was observed once a week for 8 weeks to analyse their diseases, medication used, and medicine access. About 19 (63.3%) respondents enrolled in this study were male. The mean ± SD of age was 55.87±12.486 years old. About 23(76.7%) respondent had access of medicine through hospital and 7(23.3%) by pharmacy directly. The most common chronic diseases identified were cardiovascular and endocrine disorder. Cardiovascular, alimentary tract and metabolism, and nervous system were medications most commonly used. Most of respondents used about 1-3 kind of medications in a month. About 101 kind of drugs used, 74 kinds of drug among of them were generic and 27 were non generic. About 12 (40%) respondents used vitamin and 8 (26.67%) used supplement. This study highlights respondent access of medicine through hospital and cardiovascular medicines were the most commonly used.
Co-Authors Abillah, Syamsudin Ade Rosanti AGUS PURWANGGANA Agusdini Banun Agusdini Banun Saptaningsih Ahmad Subhan AHMAD SUBHAN Ahriansyah, Andi Alfina Rianti Alfina Rianti Andalucia, Rizka Annisa Nadya Pratiwi Annisa, Rifka ARIES MERYTA Aries Meryta Arif Rahmandani Aris Aris Aritonang, MGS Arman Astrid Kartika Sari Ath-Thobari, Jarir Atmiroseva Atmiroseva Banun, Agusdini Briliana Sabirin Candra Junaedi Chaerul Y, Ricky Chandra Widianti Cipto Darmodjati Kumolo Citra Jaya Debi Susanti Desweri Muhareni Dewiyana Andari K Dian Khairunisa Dian Ratih Laksmitawati Dosi Ahmad Yani Dosi Ahmad Yani Dwi Puspita Sari, Dwi Puspita Eduward Gunawan Edwina Dharmawati Elisabeth Ninung Yuliarti Elisna Syahruddin Elsa Maulidya Erfan Chandra Nugraha Erna Kristin Evy Yunihastuti Fadhlia Majidiah Faradiba Faradiba Faridah Syamsiah Fitri Nurhayati Fitriana, Irna Fredrick D. Purba Fredrick Dermawan Purba Fredrik Dermawan Purba Hanafy, Dudy Arman Hardi, Devita Harissa, Nola Herayanti Hermawan Herty Nur Tanty Herty Nur Tanty Hesty Utami Hesty Utami Hesty Utami R Hesty Utami R Hesty Utami R Hesty Utami R Hesty Utami Ramadaniat Hidayat Hidayat ida yuliasari Ilham Maulana Irmin Irmin Irna Fitriana Jayati, Turpuk Mannaria Juju Jumiati L, Dian Ratih Leny Ramadhan M. Kenli Kendi Tampoliu Maria Sukmawati Lesilolo Maria Sukmawati Lesilolo Maura Linda Sitanggang Mawaddati Rahmi Mayasari, Yeshi Melinda, Venni MGS Aritonang MGS. Aritonang Mita Restinia Muhammad Reza Mulatsari, Esti Nanang Erlana Nanang Erlana Neneng Sri Purwaningsih Nurita Andayani NURLAYLI NURLAYLI Nurlela Nurlela Okpri Meila Petrus Kabul Togarma Pontoan, Jenny Prasasta Sutedjo Pratiwi, Annisa Nadya Prih Sarnianto Prih Sarnianto Prih Sarnianto Prih Sarnianto Prih Sarnianto R, Hesty Utami Ramadaniati, Hesty Utami Rasta Naya Pratita Reise Manninda Retnaningrum, Dyah RIA PUSPITA WARDHANI Rianti, Alfina Ricky Chaerul Yazid Rifka Annisa Rina Rosdiana Rochsismandoko Rochsismandoko Rosanti, Ade Rosdaniati Rosdaniati Rosiana, Rosiana Rulliani Bianca Wijaya S.Farm., M.Farm., Apt, Sondang Khairani Sabirin, Briliana Sahat Saragi Sahat Saragih Sari, Ratna Permana Sarnianto, Prih Sarnianto, Prih Sarwono Waspadji Septa, Tendry Setianti Haryani Setyawati Permata Siti Aisyah Siti Aisyah Suratni Suratni Suratni Suratni Tanty, Herty Nur Tarsinah Tarsinah Tarsinah, Tarsinah Tri Kusumaeni TRI KUSUMAENI Tri Kusumaeni Tri Kusumaeni Tri Kusumaeni Tri Kusumaeni, Hesty Utami R. Tri Murtini Trisna Lestari Umar Santosa Utami R, Hesty Venessya Cikita Mitakda Widya Wulan Ayu Puspitaningrum Wijaya, Rulliani Bianca William Nathanial Tj Wilson Wilson Wulan Puspitasari Wulan Puspitasari Y, Ricky Chaerul Yacob Ruru Yani, Dosi Ahmad Yati Sumiati Yati Sumiyati Yava Rony, Devi Yulia Trisna Yulia Trisna, Yulia Yuliani YULIANI Yulwa Juwita