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All Journal Indonesian Journal of Chemistry AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT JURNAL FARMASIMED (JFM) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Indah Sains dan Klinis Mejuajua Journal of Health and Medical Science Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Pengmas Kestra (JPK) FARMASAINKES Jurnal Indah Sains dan Klinis Indonesian Journal of Science and Pharmacy
Debi Meilani
Institut Kesehatan Medistra Lubuk Pakam
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Veterinary Other

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The Determination of Ascorbic in Ethanol Extract of Young and Old Kari Leaf (Murraya koenigii L. Spreng) by Spectrophotometry UV Suprianto, Suprianto; Samran, Samran; Sumardi, Sumardi; Meilani, Debi; Febriady, Andy; Andraini, Galuh
Jurnal FARMASIMED (JFM) Vol 6 No 2 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i2.1920

Abstract

Kari (Murraya koenigii L. Spreng) merupakan flora dari famili Rutaceae. Kari merupakan tumbuhan khas Srilangka, India, dan beberapa wilayah Asia Tenggara, termasuk Nusantara, Provinsi Aceh kaya akan tanaman Kari yang dikenal dengan daun Temurui. Nusantara merupakan daerah dengan beragam kekayaan alam, misalnya flora berkhasiat obat. Nusantara memiliki 30.000 jenis flora dari 40.000 jenis flora di dunia dengan 940 jenis flora berkhasiat obat. Kari merupakan salah satu flora berkhasiat obat.Daun Kari dimanfaatkan masyarakat di Nusantara sebagai rempah-rempah dan penyedap makanan, penyembuh sakit perut, pemerah kepala, obat luka, influenza, reumatik, diare, maupun diabetes, penyembuhan wasir, penurun demam dan radang serta gatal-gatal, bahkan untuk parfum maupun sabun karena beraroma khas dengan kehadiran senyawa atsirinya. Daun Kari kaya akan senyawa berkhasiat obat, diantaranya askorbat. Askorbat mudah larut dalam air namun mudah rusak, teroksidasi karena panas, atau tidak stabil oleh panas. Penentuan kandungan askorbat pada daun telah dilakukan oleh peneliti terdahulu. Kandungan askorbat dapat dilakukan secara volumetris atau dengan instrumen.Penelitian bertujuan untuk menganalisis kadungan askorbat pada ekstrak daun Kari tua dan muda dengan spektrofotometri UV. Penentuan kandungan askorbat dengan metode ini relatif murah dan baik. Kandungan askorbat ekstrak daun Kari muda dan tua masing-masing sebesar 69,97 dan 45,58 mg/g. Kandungan askorbat ekstrak daun Kari muda lebih besar dibandingkan yang tua. Penentuan kandungan askorbat pada daun telah dilakukan oleh peneliti terdahulu. Kandungan askorbat dapat dilakukan secara volumetris atau dengan instrumen. Penelitian bertujuan untuk menganalisis kadungan askorbat pada ekstrak daun Kari tua dan muda dengan spektrofotometri UV. Penentuan kandungan askorbat dengan metode ini relatif murah dan baik.Kandungan askorbat ekstrak daun Kari muda dan tua masing-masing sebesar 69,97 dan 45,58 mg/g. Kandungan askorbat ekstrak daun Kari muda lebih besar dibandingkan yang tua. Penentuan kandungan askorbat pada daun telah dilakukan oleh peneliti terdahulu. Kandungan askorbat dapat dilakukan secara volumetris atau dengan instrumen. Penelitian bertujuan untuk menganalisis kadungan askorbat pada ekstrak daun Kari tua dan muda dengan spektrofotometri UV. Penentuan kandungan askorbat dengan metode ini relatif murah dan baik. Kandungan askorbat ekstrak daun Kari muda dan tua masing-masing sebesar 69,97 dan 45,58 mg/g. Kandungan askorbat ekstrak daun Kari muda lebih besar dibandingkan yang tua. Kandungan askorbat ekstrak daun Kari muda dan tua masing-masing sebesar 69,97 dan 45,58 mg/g. Kandungan askorbat ekstrak daun Kari muda lebih besar dibandingkan yang tua. Kandungan askorbat ekstrak daun Kari muda dan tua masing-masing sebesar 69,97 dan 45,58 mg/g. Kandungan askorbat ekstrak daun Kari muda lebih besar dibandingkan yang tua.
Integration of Pharmaceutical Science in the Education of Healthy and Functional Food Preparation at SMK Negeri Pantai Labu Aritonang, Barita; Harahap, Hasni Yaturramadhan; Syarifuddin, Shofian; Meilani, Debi; Wiratma, Dicky Yuswardi
JURNAL PENGMAS KESTRA (JPK) Vol. 5 No. 1 (2025): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/1p8sw386

Abstract

The modernization of lifestyle among today’s adolescents has led to significant changes in daily consumption patterns. Many teenagers tend to prefer fast food that is high in sugar, salt, and fat, but low in nutritional value. This condition may lead to various long-term health problems if not accompanied by adequate nutritional education and awareness. This community service activity aims to integrate pharmaceutical science concepts into the education of healthy and functional food preparation at SMK Negeri Pantai Labu. The implementation method consisted of several stages: initial observation of students’ knowledge and habits, delivery of interactive educational materials, hands-on practice in preparing functional food products, and evaluation through pre-test and post-test instruments. This activity involved 30 students from the culinary arts department. Evaluation results showed a significant improvement across all aspects: knowledge of healthy food increased from 55.0 to 85.3; understanding of functional food from 47.5 to 82.0; understanding of active compounds from 41.2 to 78.5; food preparation skills from 50.4 to 80.6; and awareness of food safety from 52.8 to 86.7. The average overall improvement reached 67.3%. This community service activity concludes that an educational approach based on pharmaceutical science, when applied through culinary practice, is proven to be effective in enhancing students’ competencies, not only in terms of academic knowledge and health awareness but also in fostering entrepreneurial potential in the field of local food.
Level of Patient Satisfaction with Pharmaceutical Services in Pasar Ujungbatu Padang Lawas Health Center in 2023 Harahap, Hasni Yaturramadhan; Debi Meilani
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i1.14

Abstract

Quality pharmaceutical services are health services that can satisfy every service user in accordance with the level of patient satisfaction and the administration is in accordance with the established code of ethics and service standards. The purpose of this study was to determine the level of patient satisfaction with pharmaceutical services at the Pasar Ujungbatu Health Center, Padang Lawas Regency, Padang Lawas Regency in 2023. The research method included a descriptive method, namely using a quantitative approach to determine the level of patient satisfaction with pharmaceutical services at the Ujungbatu Market Health Center, Padang Lawas Regency. The results showed the level of patient satisfaction with pharmaceutical services at Pasar Ujungbatu Padang Lawas Health Center in 2023 with a total of 240 respondents, namely 2 people were very dissatisfied (0.83%), 4 people were dissatisfied (1.66%), 34 people were quite satisfied (14.16), 162 people were satisfied (67.5%), and 38 people were very satisfied (15.85%).
Utilization Of Ethanol Extract Of Wungu Leaf (Graptophyllum Pictum (L) Griff) Growing In The Pamah Deli Old Area As An Anti-Inflammatory Meilani, Debi; Miranda, Novia Anisa; Ardiani, Rani; Rahmi, Sofia; Yaturramadhan, Hasni
Indonesian Journal of Science and Pharmacy Vol. 1 No. 2 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i2.20

Abstract

Wungu leaves (Graptophyllum pictum (L) Griff) are often used as traditional medicine, contain several chemical compounds, including alkaloids, glycosides, steroids, saponins, tannins and flavonoids and chemical compounds, thought to have anti-inflammatory properties. The aim of this study was to utilize the ethanol extract of Wungu leaves that grow in the Pamah Deli Tua area, North Sumatra, as an anti-inflammatory. This study included characterization of simplicia, phytochemical screening and testing of the anti-inflammatory activity of the ethanol extract of Wungu leaves (EEDW). Measurement of rat leg volume induced by 1% λ-carrageenan using a plestimometer, observations were made every 30 minutes for 6 hours. This study used 5 treatment groups, namely group I was given 0.5% CMC suspension, group II was given diclofenac sodium at a dose of 4.5 mg/kg BW, group III was given EEDW at a dose of 100 mg/kg BW, group IV was given EEDW at a dose of 200 mg /kg BW, group V was given EEDW at a dose of 400 mg/kg BW. Inflammation percentage and inflammation inhibition percentage were calculated. Data were analyzed by Duncan to see whether or not there was a difference between the groups. The results showed that there were significant differences between the doses of 100, 200 and 400 mg/kg BW, but between the doses of 400 mg/kh BW and diclofenac sodium there were no significant differences. The percentage of inflammation at a dose of 400 mg/kg BW was 3,366 and the percentage of inflammation inhibition was 86,569%. The higher the dose of EEDW the more effective it is as an anti-inflammatory, and the dose of 400 mg/KgBB in rats is the optimum dose of EEDW as an anti-inflammatory.
The Formulation Cream Of Black Cumin Seed Oil (Nigella sativa Linn.) Utami, Dinda Sari; Lubis, Minda Sari; Meilani, Debi
Indonesian Journal of Science and Pharmacy Vol. 1 No. 2 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i2.38

Abstract

Indonesia is rich in natural resources, has done a lot of research on the utilization of natural materials. Nigella sativa Linn. or in Indonesia known black jintan has pain relieving or analgesic and anti-inflammatory properties. The aim of this study is to determine the antinyeri effect of black ginger oil on white male rats by plantar test method. Black ginger seed oil is standardized and performed test effectiveness, then black gender oil is made cream with concentrations of 5ml, 10ml, and 20ml. Observations were performed for the occurrence of muscle antinyeri every 15 minutes during the time the plantar test device stopped when the mice licked their legs and hands.The test results of the standardization of black geranium seed oil obtained type weight in black germanium oil 0.958 g/ml, water content 0.000056%, and acid count 39.97 ml/g. Physical quality test results the preparation of the cream no bruising with the oil emulsion type in water that is easily washed with water as well as pH adjusted with the skin with range 7.3-7.6 and the cream does not undergo color change, shape and rupture emulsions.
Penetapan Kadar Formalin Pada Mie Basah Yang Beredar Di Pasar Peunayong Kota Banda Aceh Secara Spektrofotometri Visible Syarifah Nadia; Debi Meilani; Dea Anggreini; Siti Rahmi Ningrum; Supran Hidayat Sihotang; Ernawaty Ginting
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 2 (2025): Agustus : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i2.6296

Abstract

Formalin is a 37% formaldehyde solution in water, commonly misused as a food preservative despite its toxicity and prohibition in food products. This study aimed to determine the presence and levels of formalin in wet noodles sold at Peunayong Market, Banda Aceh, using visible spectrophotometry. A descriptive design was applied to three randomly selected samples. Qualitative tests using multiple reagents (Schiff, Schryver, KMnO₄, and a test kit) showed negative results for formalin presence. However, quantitative analysis with Spectroquant Prove 300 revealed that all samples contained formalin levels exceeding the acceptable standard. The concentrations ranged from 0.7433 mg/L to 0.8766 mg/L, indicating that the products are unsafe for consumption. These findings underline the need for stricter monitoring and improved food safety awareness among producers and consumers in traditional markets.
Formulasi Dan Uji Aktivitas Antipiretik Plester Hidrogel Ekstrak Etanol Daun Sirsak (Annona muricata L.) Murina, Debi Meilani
Journal of Health and Medical Science Volume 3 Nomor 1 Januari 2024
Publisher : CV. Pusdikra Mitra Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Fever is a condition in which the body temperature is more than 37 °C, fever can also be an early clinical manifestation of a particular infection. A person is said to have a fever when the body temperature is above normal. Soursop plant (Annona muricata L.) is one of the plants that have antipyretic effects because it contains secondary metabolite compounds, namely flavonoids that can reduce fever. The objective of the research was to simulate the Formulation and Antipyretic Activity Test of Hydrogel Plasters of Soursop Leaf Ethanol Extract (Annona muricata L.) Soursop leaf ethanol extract is made by the maceration method, formulated as a hydrogel plaster with different concentrations of 5 g, 7.5 g, and 10 g. and then testing is carried out which includes organoleptic tests, pH tests, viscosity tests, homogeneity tests, and temperature reduction tests on mice. The test data obtained was then analyzed using SPSS (Statistical Package for The Social Sciences) and the Anova test was then continued using the Tukey test. The results showed that the three hydrogel preparations had the same organoleptic results, namely semi-solid shape, distinctive smell and dark green brownish. The pH of the hydrogel includes 5 - 6.2, viscosity 89510 - 106530 cP and homogeneous preparations. The results of the test of the decline in body temperature of mice test animals showed that the most effective formula was hydrogel plaster with a composition of 10 g of extract in 30 g of preparations can lower the body temperature of mice in the fastest time, which is 60 minutes.
Aktivitas Antibakteri Ekstrak, Fraksi Kloroform dan Fraksi n-Heksan Daun Kemangi terhadap Staphylococcus aureus dan Eschericia coli Melati Yulia Kusumastuti; Debi Meilani; Suhendra Tawarnate
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.11

Abstract

Basil (Ocimum citriodorumVis.) is a plant which is their leaves are commonly eaten as fresh vegetables and have many benefits. Basil leaves contain secondary metabolite compounds that have antibacterial activity such as flavonoids, tannins, saponins, alkaloids, and steroids. The purpose of this study was to known the antibacterial activity of some fractions of basil leaves against Escherichia coli and Staphylococcus aureus and see which fraction was more active. This research included extraction by maceration method using ethanol 96%, then ethanol extract was fractionated using n-hexane and chloroform, phytochemical screening, then tested for antibacterial activity against E. coli and S. aureus by used agar diffusion method. Phytochemical screening showed ethanol extractcontained alkaloids, saponins, flavonoids, tannins, and steroids; chloroform fraction contained alkaloids, flavonoids, saponins, and tannins; and n-hexane fraction contained steroids. The results of the antibacterial activity test showed ethanol extract and chloroform fraction had antibacterial activity. Meanwhile, the n-hexane fraction did not have antibacterial activity. The concentration of 500 mg/ml of chloroform fraction and ethanol extract on S. aureus resulted from an inhibition zone around 24.67-26.90 mm. Furthermore, E. coli produced 22.67-23.84 mm. Ethanol extract had higher antibacterial activity than the chloroform fraction against E. coli and S. aureus
Evaluasi Stabilisator Agar-Agar dan CMC Sediaan Sirup Markisa Berastagi Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Cut Fatimah; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/b1pzvs47

Abstract

Fruit syrup is made from a sugar solution, the taste and aroma are determined by the freshness of the fruit. Fruit commonly used in making syrup has an attractive color, aroma and distinctive taste. Passion fruit (Passiflora edulis Sims.) has a distinctive taste and aroma, so it is widely processed into syrup. This study was to evaluate CMC and Agar-Agar stabilizers in the passion fruit syrup formula. Evaluation includes color, appearance, texture, taste and aroma and hedonic tests are carried out. The results showed that there were significant differences in the color, appearance, texture, taste and aroma of passion fruit syrup. Stabilizers CMC and Agar-Agar make the color, texture and appearance of the syrup better and more attractive. The result of hedonic test for ideal syrup concentration is S3 with 4 g of Agar and 6 g of CMC. The higher the concentration of CMC and Agar, the greater the viscosity of the syrup. The concentration of CMC and Agar-agar in a mixture of fruit juices gave significantly different effects on color, texture, appearance, taste and aroma
Formulasi dan Evaluasi Sediaan Sabun Padat Antiseptik Ekstrak Etanol Daun Kunyit Suprianto; Sumardi; Debi Meilani; Sri Rahayu
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.44

Abstract

The plant of findings turmeric (Curcuma longa) are often used as a traditional medicinal. The part of the turmeric plant that is often used is the rhizome. In addition to turmeric rhizome, turmeric leaves are also used as a flavoring dish. Among the benefits of turmeric leaves is as an antimicrobial. Soap is a surfactant used for washing and cleaning. Antiseptics are inhibitors for the growth and development of microorganisms that live on the surface of the body. The study was to determine which ethanol extract of turmeric leaves could be formulated into antiseptic solid soap preparations. This study used an experimental method, turmeric leaves were extracted with 70% ethanol. The formula made are 2.5%, 5%, 7.5%. The quality of the soap preparation was carried out by organoleptic tests, acidity, high foam and irritation. The results test showed that the solid soap did not have the aroma of turmeric leaves, the pH of the soap was 9.9-10.5; foam height with a concentration of 7.5% which is 7.3 cm; and solid soap preparations ethanol extract of turmeric leaves did not cause irritation. The extract of turmeric leaves can be formulated into solid soap preparations. It is recommended to add perfume to the formulation of solid soap preparations of turmeric leaf extract as an antiseptic.
Co-Authors Adek Chan Agus Kristina Ahmad Hafizullah Ritonga Alam Suhada Ancel Mus Silaban Andraini, Galuh Andy Febriadi Ardiani, Rani Aritonang, Barita Ayu Khairunnisa Cahya, Cucu Arum Dwi Chan, Adek Cut Fatimah Cut Fatimah Dea Anggreini Deliwarni Rajagukguk Dewi Kartika Dian Zulkarnain Lubis Dicky Yuswardi Wiratma Dinda Sari Utami Elvy Oktima Ernawaty Ginting Eva Sartika Dasopang Fatimah Sari Simatupang Febriady, Andy Fesri Damai Riang Laia Gabena Indrayani Dalimunthe Harahap, Hasni Yaturramadhan Hasni, Hasni Yaturramadhan Harahap Herlina . Joko Wibowo Karnirius Harefa Khairiah, Khairiah Lidiya Sasmaita Sihotang Lubis, Minda Sari Mandike Ginting Mandike Ginting Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Miranda, Novia Anisa Muhammad Gunawan Muhammad Gunawan Nasirah Maulidia Ajhar Nasution, Lely Fitri Handayani Putri, Gusliani Eka Rahmi, Sofia Regina Elyanda Tampubolon Reni Aprinawaty Sirait Riza Hasyati Rotua Sumihar Sitorus Samran, Samran Shofian Syarifuddin Siahaan, Enzo W.B Sitepu, Rahmadani Siti Fatimah Hanum Siti Fatimah Hanum Siti Rahmi Ningrum Sofyan Syarifuddin Sri Rahayu Sri Rahayu Suhendra Tawarnate Suhendra Tawarnate Suhendra Tawarnate Sumardi Sumardi Sumardi . Supran Hidayat Sihotang Suprianto Suprianto Suprianto Syarifah Nadia Syarifuddin, Aminah Nur Syarifuddin, Shofian Wibman Tambunan Yaturramadhan, Hasni Yessy Febriani Yosi Darmirani Yuniarti, Rafita