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All Journal Jurnal SOLMA Indonesian Journal of Global Health research Journal of Holistics and Health Sciences (JHHS) Prosiding University Research Colloquium Journal of Innovative and Creativity Jurnal Abdimas Indonesia International Journal of Health Science Fundamental and Applied Research in Medicine and Allied Sciences Indonesia
Emma Jayanti Besan
Universitas Muhammadiyah Kudus
Religion Humanities Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Vulnerability of Critical Medicine Supply Chains in Remote Islands: A System Dynamics Study in Maluku, Indonesia Fendy Prasetyawan; Emma Jayanti Besan; Muhammad Nurul Fadel; Ika Lismayani Ilyas
Fundamental and Applied Research in Medicine and Allied Sciences Indonesia Vol. 1 No. 2 (2025): November, 2025
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/farmasi.v1i2.431

Abstract

Ensuring the continuous availability of critical medicines in remote island regions remains a major challenge in decentralized health systems. This study examines the pharmaceutical supply chain in the remote islands of Maluku Province, Indonesia, through a supply chain mapping and vulnerability analysis using a System Dynamics (SD) approach. The findings indicate that fragmented governance structures, combined with extreme geographical dispersion, generate persistent vulnerabilities across procurement, distribution, and service delivery levels. Key reinforcing mechanisms driving medicine stockouts include delayed quantification and procurement processes, logistical bottlenecks in inter-island transportation, and shortages of skilled pharmaceutical personnel. The analysis further shows that interventions focused solely at the health facility level are insufficient to resolve systemic weaknesses. Instead, strengthening medicine security in Maluku requires integrated strategies at higher administrative levels, including investment in human capital, diversification of supply routes, strategic buffer management, and the use of transparent, data-driven logistics information systems. By adopting a systems-based analytical framework, this study provides evidence to support more resilient policy design for improving equitable access to essential medicines in Eastern Indonesia.
Green Synthesis of Silver Nanoparticles Using Tamarind (Tamarindus indica) Leaf Extract and Their Application as an Antibiofilm Agent in Pseudomonas aeruginosa Infected Wounds Emma Jayanti Besan; Muhammad Nurul Fadel; Cut Intan Annisa Puteri; Dzukharian Munandar; Putri Tri Hartini
Fundamental and Applied Research in Medicine and Allied Sciences Indonesia Vol. 1 No. 2 (2025): November, 2025
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/farmasi.v1i2.434

Abstract

Multidrug-resistant Pseudomonas aeruginosa poses a significant challenge in chronic wound management due to its robust biofilm formation and antibiotic resistance. Green-synthesized silver nanoparticles (AgNPs) using Tamarindus indica (tamarind) leaf extract offer an eco-friendly and effective approach to combat these infections. The bioactive phytochemicals in tamarind leaves function as both reducing and stabilizing agents, producing biocompatible AgNPs with potent antimicrobial and antibiofilm activities. These nanoparticles disrupt bacterial membranes, generate reactive oxygen species, inhibit virulence factors such as pyocyanin, and compromise biofilm integrity. Incorporation of tamarind-derived AgNPs into hydrogels or composite wound dressings further enhances wound healing by maintaining a moist environment and providing sustained antimicrobial release. Although in vivo studies specifically using tamarind AgNPs against P. aeruginosa are limited, evidence from other plant-derived AgNPs supports their promising potential for treating biofilm-associated wound infections. Green synthesis using tamarind thus represents a sustainable strategy for developing next-generation antimicrobial wound therapies.
PENDEKATAN EDUKATIF KANKER PANGKAL RAHIM SERVIKS PADA KELOMPOK ‘AISYIYAH KABUPATEN KUDUS Emma Jayanti Besan; Indah Puspitasari; Fania Nurul Khoirunnisa; Nor Asiyah; Diah Andriani Kusumastuti; Indanah Indanah; Muhammad Nurul Fadel; Wan Ismahanisa Ismail
Jurnal Abdimas Indonesia Vol 8, No 1 (2026): JURNAL ABDIMAS INDONESIA
Publisher : Universitas Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/jai.v8i1.3174

Abstract

Kanker serviks merupakan salah satu penyebab utama kematian perempuan di Indonesia dengan angka kejadian tinggi dan masih rendahnya tingkat deteksi dini. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan dan kesadaran ibu-ibu ‘Aisyiyah Kabupaten Kudus mengenai faktor risiko, pencegahan, dan deteksi dini kanker serviks melalui pendekatan edukatif. Metode yang digunakan berupa penyuluhan interaktif dengan media audiovisual, diskusi, serta evaluasi pre-test dan post-test. Kegiatan diikuti oleh 44 peserta dan dilaksanakan di Aula Panti Asuhan Prambatan Kudus. Hasil evaluasi menunjukkan peningkatan pengetahuan peserta dari rata-rata 62% menjadi 90% setelah kegiatan. Antusiasme tinggi terlihat dari partisipasi aktif dalam sesi tanya jawab. Edukasi berbasis ceramah interaktif dan audiovisual terbukti efektif meningkatkan kesadaran peserta mengenai pentingnya skrining dan vaksinasi HPV. Kegiatan ini sejalan dengan strategi nasional pencegahan kanker serviks melalui pendekatan promotif dan preventif di masyarakat. Diharapkan kegiatan edukatif semacam ini dapat menjadi model pemberdayaan perempuan dalam mendukung upaya eliminasi kanker serviks di tingkat komunitas. Cervical cancer is one of the leading causes of death for women in Indonesia, with a high incidence rate and low early detection rates. This community service activity aims to increase the knowledge and awareness of women from the 'Aisyiyah group in Kudus Regency regarding risk factors, prevention, and early detection of cervical cancer through an educational approach. The methods used were interactive counseling with audiovisual media, discussions, and pre- and post-test evaluations. The activity was attended by 44 participants and was held in the Prambatan Kudus Orphanage Hall. The evaluation results showed an increase in participants' knowledge from an average of 62% to 90% after the activity. High enthusiasm was evident in active participation in the question and answer session. The interactive lecture-based education and audiovisuals have proven effective in increasing participants' awareness of the importance of HPV screening and vaccination. This activity aligns with the national strategy for cervical cancer prevention through a promotive and preventive approach in the community. It is hoped that this educational activity can become a model for women's empowerment in supporting cervical cancer elimination efforts at the community level.
Antibacterial Potential of Ethanol Extract Cream of Kersen Leaves (muntingia Calabura L) Against Pseudomonas Aeruginosa Muhammad Nurul Fadel; Emma Jayanti Besan; Muhammad Ridwanto
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.5187

Abstract

Bacterial infections remain a substantial health concern. Several resistant microorganisms can induce bacterial infections, including Pseudomonas aeruginosa. Some research indicate that Kersen leaves (Muntingia calabura L), due to its flavonoids, tannins, and saponins that have undergone clinical testing, possess antibacterial characteristics. This study seeks to evaluate the antibacterial efficacy of a 96% ethanol extract cream derived from Kersen leaves (Muntingia calabura L) against the proliferation of Pseudomonas aeruginosa bacteria. The research performed was experimental in a laboratory setting. The procedure for evaluating antibacterial efficacy via the disc diffusion method utilising formulations of 0%, 5%, 10%, 15%, and gentamicin. The technique of data analysis employing One Way ANOVA to discover differences in data. The antibacterial activity of the cream against Pseudomonas aeruginosa was tested, yielding a 5% inhibition of 17.33 mm (strong category), 10% inhibition of 19.00 mm (strong category), and 15% inhibition of 22.66 mm (very strong category). The research concludes that a 96% ethanol extract cream of Kersen leaves (Muntingia calabura L) possesses the potential to suppress the growth of Pseudomonas aeruginosa bacteria.
Gerakan Edukasi Cerdas Kosmetik Aman: Pemberdayaan Remaja sebagai Agen Perubahan di Sekolah Emma Jayanti Besan; Intan Adevia Rosnarita; Muhamad Khudzaifi; Fahrudin Arif; Nafisa Zaharani Hidayanti; Fina Aulia Maharani
Jurnal SOLMA Vol. 15 No. 2 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v15i2.23436

Abstract

Background: Penggunaan kosmetik di kalangan remaja semakin meningkat seiring berkembangnya tren kecantikan dan media sosial, namun kondisi ini juga meningkatkan risiko penggunaan kosmetik ilegal dan berbahaya akibat rendahnya literasi kesehatan remaja. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan, kesadaran, dan kemampuan siswa dalam memilih kosmetik yang aman serta membentuk remaja sebagai agen perubahan di lingkungan sekolah. Metode: Kegiatan dilakukan melalui penyuluhan interaktif, demonstrasi penggunaan aplikasi Cek BPOM, diskusi, serta evaluasi menggunakan pre-test dan post-test pada 78 siswa SMK Terpadu Bhakti Indonesia, Pati, Jawa Tengah. Hasil: Analisis data menunjukkan nilai signifikansi p=0,000 (<0,05), yang menandakan terdapat perbedaan bermakna sebelum dan sesudah edukasi diberikan. Edukasi interaktif dan praktik langsung penggunaan aplikasi Cek BPOM terbukti efektif meningkatkan literasi kesehatan siswa terkait keamanan kosmetik, legalitas produk, dan bahaya kosmetik ilegal. Program ini juga berpotensi membentuk siswa sebagai peer educator dalam menyebarluaskan informasi kosmetik aman kepada masyarakat. Kesimpulan: Kegiatan ini dapat menjadi model promosi kesehatan preventif berbasis sekolah untuk meningkatkan kesadaran remaja terhadap penggunaan kosmetik yang aman dan legal.
Co-Authors Afif putri Habibah Ahmad Suriyadi Muslim Ainun Najah Atun Qowiyyah Bintari Tri Sukoharjanti Diah Andriani Kusumastuti Dzukharian Munandar Eko Retnowati Endang Setyowati Fahrudin Arif Fania Nurul Khoirunnisa Fendy Prasetyawan Fina Aulia Maharani Fitri Apriliani Galih Kurniawan Hartini, Putri Tri Hasriyani Hidayah Karuniawati Ika Lismayani Ilyas Ika Sinta Indriani Indah Puspitasari Indanah Intan Adevia Rosnarita Julia Megawati Djamal Korinus Suweni Muhamad Khudzaifi Muhammad Da&#039;i Muhammad Nurul Fadel Muhammad Nurul Fadel Muhammad Ridwanto Nafisa Zaharani Hidayanti Nihayatus Sholekhah Nina Irmayanti Harahap Nor Asiyah Nor Halimah Nur Masyithah Zamruddin Nurlena Ikawati Puteri, Cut Intan Annisa Riana Putri Rahmawati Ulfa Nabila Besan Wan Ismahanisa Ismail Yunita Kristina Zaenal Fanani Ziza Putri Aisyia Fauzi