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All Journal Jurnal Kesehatan Andalas Jurnal Kesehatan Melayu Buletin Ilmiah Nagari Membangun Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Andalas Jurnal Ilmu Kesehatan Indonesia (JIKSI) SENTRI: Jurnal Riset Ilmiah Jurnal Sains, Teknologi dan Kesehatan
Dolly Irfandy
Dr. M. Djamil Hospital / Faculty Of Medicine Universitas Andalas, Padang
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Risk Factors for Olfactory Dysfunction in Hospital Setting Following Covid-19 Infection Among Hospital Employees Following Treatment of Covid-19 Infected Patients: A Survey Research Irfandy, Dolly; Afriwardi, Afriwardi; Budiman, Bestari J.; Putra, Andani E.; Elvira, Dwitya; Triananda, Claudia
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 7 (2025): SENTRI : Jurnal Riset Ilmiah, Juli 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i7.4272

Abstract

Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To reveal the risk factors for olfactory dysfunction in employees with COVID-19 in the workplace of the subject hospital in Indonesia. This study was quantitative and descriptive, using data from questionnaires distributed to subject hospital in Indonesia employees who have experienced COVID-19. This study shows that anosmia (33.2%) is the most common olfactory dysfunction in COVID-19. COVID-19 infection often occurs in resident doctors (58.1%); women (55.6%); those aged 55 years (92.3%); those with comorbidities such as hypertension (4.3%) and obesity (65%); nonsmokers (91.5%) and smokers 10–20 cigarettes per day (5.1%); and nondrinkers (100%). Anosmia is the most common olfactory dysfunction in COVID-19. It is commonly experienced by resident doctors, women aged ≥55 years, employees without comorbidities, obese employees, nonsmokers, and nondrinker
Pengaruh Pemberian Human Wharton’s jelly mesenchymal stem cells Terhadap Gambaran Histopatologi Sel Hepatosit yang Diinduksi Aluminium Klorida Putri Amran, Fajriana Anggun; Nita Afriani; Dolly Irfandy; Eryati Darwin; Eka Nofita; Tofrizal
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 3 (2025): September 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i3.1508

Abstract

Latar Belakang:   Aluminium klorida (AlCl3) adalah zat hepatotoksik yang dapat ditemukan dalam air, udara, serta berbagai bahan makanan , sehingga manusia berpotensi terpapar setiap hari. Paparan kronis AlCl3 diketahui menimbulkan akumulasi pada hepar yang berujung pada kerusakan hepatosit. Gambaran histopatologi khas akibat paparan toksik ini meliputi degenerasi hidrofik, piknosis, karioreksis, kariolisis, dan nekrosis.  Dengan. Human Wharton’s jelly mesenchymal stem cells (HWJ-MSCs), yang berasal dari jaringan mucoid plasenta, memiliki sifat multipotent, regenerative dan imunomodulator, sehingga berpotensi memperbaiki kerusakan hepatosit. Objektif:    Penelitian ini bertujuan unutuk mengetahui pengaruh pemberian HWJ-MSCs terhadap gambaran histopatologi sel hepatosit tikus yang diinduksi aluminium klorida Metode:    Penelitian eksperimental laboratorik dengan desain Post Test Only Control Group dilakukan pada 18 ekor tikus wistar jantan. Hewan dibagi menjadi tiga kelompok : kontrol negative, kontrol positif dengan induksi AlCl3 dan perlakuan dengan induksi AlCl3 ditambah pemberian HWJ-MSCs. Hepar difiksasi, diproses histologis, dan diwarnai menggunakan H&E. Presentase kerusakan hepatosit dinilai pada tiga lapangan pandang dengan pembesaran 400x Hasil:      Rerata kerusakan hepatosit adalah 1,7% pada kontrol negative, 68,7% pada kontrol positif, dan 35,8% pada kelompok perlakukan. Tampak perbaikan gambaran histopatologi pada kelompok perlakuan dibanding kelompok kontrol kontrol positif. Kesimpulan:  Pemberian HWJ-MSCs berpotensi menurunkan kerusakan hepatosit akibat induksi AlCl3 meskipun dosis yang diberikan belum cukup untuk mengembalikan kondisi sel hepatosit normal.
Co-Authors Ade Asyari Adrial Adrial, Adrial Afriwardi Afriwardi Aini Zhann Al Hafiz Al Hafiz Al Hafiz Ariani, Novita arif fahmi Arni Amir Asterina, Asterina Aziz Djamal Bestari J. Budiman Bestari Jaka Budiman Bestari Jaka Budiman Bonny Murizky Deka Viotra Delfitri Munir Della Reyhani Putri Delmi Sulastri Desy Ambriani Dewi Yuri Lestari Dwininta Alfathika Dwitya Elvira, Dwitya Effy Huriyati Efrida Ermayanti, Sabrina Eryati Darwin Esmaralda Nurul Amany Fachzi Fitri Fariz, Kamal Fika Tri Anggraini Firdawati Firdawati Furqan, Muhammad Afif Hanum, Fathiya Juwita Hendradewi, Sarwastuti Hendriati, Hendriati Hera Novianti Hesty Lidya Ningsih Husna Yetti Ihsan, Indra Ikhlas, Khairani Ayunanda Irwandanon Irwandanon Jacky Munilson Kusuma Dewi, Anna Mailasari Lucky Berliandi Magdi, Yoan Levia Mardijas Efendi Mayorita, Pamelia Mohd Redza Qurniawan Muhammad Farel Brian Nugraha Muhammad Farhan Ramadhan Muhammad Reko Danuwirya Nirza Warto Nita Afriani Novialdi . Novita Ariani Nurul Ramadhini Oktavia, Mutiara Pamelia Mayorita Pamelia Mayorita Pramita, Arsia Dilla Primasakti, Pattih Putra, Andani E. Putri Amran, Fajriana Anggun Putri Sari Ivanny Rahmadona Rahmadona Rimelda Aquinas Rizanda Machmud Rizki Saputra Rossy Rosalinda Salshabilla, Miftah Sariwati, Siska Satya Wydya Yenny Sinta Sari Ratunanda Sukri Rahman Sutikno, Budi Tika Hakikah Tofrizal tri aryati octavia Triananda, Claudia Vitresia, Havriza Wardani, Retno Sulistyo Yan Edward Yolazenia Yolazenia Yuniar Lestari Yunita Wulandari Zakiah, Azmi Mir’ah