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PENERAPAN CASE BASED METHOD DALAM EDUKASI PRAPUBERTAS SISWA USIA SEKOLAH DASAR Subandrate, Subandrate; Amalia, Ella; Rahayu, Sri; Safyudin, Safyudin
Kreativitas Pada Pengabdian Masyarakat (Krepa) Vol. 5 No. 1 (2025): Kreativitas Pada Pengabdian Masyarakat (Krepa)
Publisher : CV SWA Anugerah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.8765/krepa.v5i1.12492

Abstract

Siswa sekolah dasar (SD) laki-laki prapubertas berada pada fase perkembangan yang penting, di mana mereka mulai mengalami perubahan fisik, emosional, dan psikologis yang signifikan. Untuk membantu siswa SD laki-laki prapubertas memahami dan mengelola perubahan yang terjadi dalam tubuh mereka, pendekatan yang dapat digunakan adalah dengan memberikan pengajaran tentang pendidikan seks dan hormon seks. Penerapan case-based method dapat membantu siswa memahami perubahan fisik dan emosional yang terjadi pada masa prapubertas secara konkret. Kegiatan pengabdian ini diikuti oleh 43 siswa laki-laki dari kelas empat, kelas lima, dan kelas enam. Sebagian besar siswa berumur 11 tahun. Pembicara mengambil tema “Saleh di Masa Pubertas” dengan tiga subtopik yakni tahapan proses penciptaan manusia, proses pertumbuhan dan perkembangan manusia, dan masa dan tanda pubertas pada laki-laki. Pada pengabdian ini, didapatkan ada dua anak (4,7%) yang sudah mengalami pubertas. Sebagian besar siswa dapat memahami topik dengan baik (55,8%). Kegiatan pengabdian kepada masyarakat dilaksanakan dengan baik. Siswa senang dengan metode berbasis kasus yang digunakan pada kegiatan ini. Mereka berharap topik-topik edukasi dapat diberikan dengan metode tersebut. Peran utama dari penerapan metode ini adalah untuk mendorong siswa berpikir kritis, memecahkan masalah, dan memahami konsep-konsep yang kompleks melalui penerapan pengetahuan dalam situasi nyata.
Identification of Mitochondrial DNA Polymorphism on Linezolid-induced Toxic Optic Neuropathy Patients Setyorini, Dwi Indira; Ahmad, Zen; Amalia, Ella; Subandrate, Subandrate; Hutabarat, Yosafat Beltsazar
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14240

Abstract

Drug-resistant tuberculosis (DR-TB) is difficult to eradicate due to several factors, including insufficient treatment and medication side effects. Linezolid is among the medications with serious adverse effects. Linezolid toxicity is suspected to be related to the drug's binding to mitochondrial 16s rRNA. Some studies indicate that polymorphisms in patients' mtDNA may increase vulnerability to the development of toxic optic neuropathy. This study aims to identify a genetic influence on the vulnerability to the occurrence of toxic optic neuropathy side effects in drug-resistant tuberculosis patients receiving linezolid treatment. This research was conducted at the Faculty of Medicine, Universitas Sriwijaya, Palembang, from September to October 2023. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was undertaken to detect mutations in the G3010A mtDNA of the patients. Two patients experiencing toxic optic neuropathy side effects during drug-resistant tuberculosis treatment underwent blood sample collection. Blood samples were examined for mutations in the G3010A and A2706G genes using the PCR-RFLP method. The PCR-RFLP examination results indicated the presence of mutations in G3010A. In conclusion, polymorphism of G3010A mtDNA may contribute to the vulnerability to toxic optic neuropathy side effects in drug-resistant tuberculosis patients receiving linezolid. Further research with a larger population is needed to prove the involvement of mtDNA polymorphisms in the vulnerability to toxic optic neuropathy.
Identification of Mitochondrial DNA Polymorphism on Linezolid-induced Toxic Optic Neuropathy Patients Setyorini, Dwi Indira; Ahmad, Zen; Amalia, Ella; Subandrate, Subandrate; Hutabarat, Yosafat Beltsazar
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14142

Abstract

Drug-resistant tuberculosis (DR-TB) is difficult to eradicate due to several factors, including insufficient treatment and medication side effects. Linezolid is among the medications with serious adverse effects. Linezolid toxicity is suspected to be related to the drug's binding to mitochondrial 16s rRNA. Some studies indicate that polymorphisms in patients' mtDNA may increase vulnerability to the development of toxic optic neuropathy. This study aims to identify a genetic influence on the vulnerability to the occurrence of toxic optic neuropathy side effects in drug-resistant tuberculosis patients receiving linezolid treatment. This research was conducted at the Faculty of Medicine, Universitas Sriwijaya, Palembang, from September to October 2023. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was undertaken to detect mutations in the G3010A mtDNA of the patients. Two patients experiencing toxic optic neuropathy side effects during drug-resistant tuberculosis treatment underwent blood sample collection. Blood samples were examined for mutations in the G3010A and A2706G genes using the PCR-RFLP method. The PCR-RFLP examination results indicated the presence of mutations in G3010A. In conclusion, polymorphism of G3010A mtDNA may contribute to the vulnerability to toxic optic neuropathy side effects in drug-resistant tuberculosis patients receiving linezolid. Further research with a larger population is needed to prove the involvement of mtDNA polymorphisms in the vulnerability to toxic optic neuropathy.
The Role of Cell Membranes in Cell Traffic Rara Inggarsih; Amalia, Ella; Septi Purnamasari
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.168

Abstract

The cell membrane plays an important role in cell traffic because it functions to secrete various molecules. The selective transport system allows the movement of molecules into or out of the cell compartment. By controlling the movement of substances from one compartment to another, membranes exert a strong influence on metabolic pathways. Cell membranes are composed of proteins and lipids with a very important function in maintaining the rhythm of circulation and cell transport. In addition, the cell membrane also plays a role in maintaining the integrity and relationship, and communication of cells.
Improving the Knowledge of Health Cadres for Stunting Prevention through Emotional Demonstration Technique Etrawati, Fenny; Lionita, Widya; Amalia, Ella; Rahmawati, Fuji; Meilinda, Nurly; Rahmawaty, Annisa
Indonesian Journal of Human Nutrition Vol. 10 No. 2 (2023)
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijhn.2023.010.02.3

Abstract

Stunting has become a dietary concern in Indonesia. Ogan Komering Ilir district of South Sumatra Province has a stunting prevalence exceeding 20%, highlighting a significant public health concern according to WHO. Addressing this challenge requires the active involvement of health cadres, who play a pivotal role in enhancing maternal and child health. This study aimed to enhance the knowledge of health cadres in stunting prevention through the application of the emotional demonstration method at the village level. A total of 23 active cadres from the healthcare system were purposefully selected to participate in this activity. The experiment group, consisting of 12 cadres, underwent training using the emotional demonstration method through interactive games, while the control group, totaling 11 cadres, followed conventional methods, such as lectures. The activity was held with separate sessions for each group. The participants’ knowledge was measured using questionnaires covering the understanding of stunting, exclusive breastfeeding, complementary foods, anemia, and sources of nutrients. Data were analyzed using a dependent t-test. Average pre-post knowledge gains were 1.15 scores higher for experiment groups compared to 0.19 scores higher for control groups. Statistically significant changes in knowledge scores were observed in the experiment group (p = 0.002), while the control group showed insignificant changes (p = 0.321). Education activities employing emotional demonstration through interactive games are effective in increasing knowledge of stunting prevention.
PENINGKATAN LITERASI KESEHATAN TENTANG PENYAKIT INFEKSI EMERGING DAN REEMERGING MELALUI SEMINAR DARING NASIONAL BAGI MAHASISWA DAN TENAGA KESEHATAN Rivani, Erizka; Amalia, Ella; Sabrina, Tia; Diba, Masayu Farah; Nawawi, Rizki Andini; Usman, Doni
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 9 No. 2 (2024): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v9i2.3403

Abstract

Penyakit infeksi emerging dan reemerging merupakan tantangan yang semakin signifikan dalam dunia kesehatan dalam beberapa tahun terakhir, terutama diakibatkan oleh makin berkembangnya globalisasi, urbanisasi, dan juga perkembangan teknologi di dunia. Berbagai penyakit infeksi baru bermunculan, dan penyakit infeksi yang telah dikenal sejak dahulu mengalami perubahan dari segi manifestasi klinik maupun tantangan dalam deteksi dan tata kelola. Hal ini membuat manajemen dari penyakit infeksi emerging dan reemerging menjadi unik dari segi kebaruan dan pengenalan penyakit. Pengabdian masyarakat dalam bentuk seminar bagi tenaga kesehatan diharapkan dapat meningkatkan kewaspadaan akan penyakit, termasuk bagi mahasiswa yang kelak akan menjadi bagian dari praktisi kesehatan. Seminar diadakan secara daring untuk memperluas cakupan acara sehingga dapat diikuti oleh peserta dengan berbagai latar belakang profesi kesehatan dari seluruh Indonesia. Materi yang disampaikan mencakup tantangan klinis dan manajemen penyakit serta peran laboratorium mikrobiologi klinik dalam deteksi dan pencegahan penyakit infeksi emerging dan reemerging. Terdapat peningkatan persentase jawaban benar dan nilai rerata dari post-test yang dikerjakan oleh peserta pasca paparan materi dibandingkan dengan pre-test. Adanya diskusi interaktif setelah paparan juga menunjukkan ketertarikan peserta akan materi yang disampaikan yang dinilai relevan untuk praktik klinis sehari-hari. Kegiatan pengabdian masyarakat ini memberikan dampak positif berupa peningkatan pemahaman dan motivasi peserta untuk menerapkan ilmu yang didapatkan dalam manajemen, deteksi, dan pencegahan penyakit infeksi emerging dan reemerging. Seminar daring diharapkan dan menjadi model edukasi berkelanjutan untuk meningkatkan kesiapsiagaan dalam menghadai perkembangan ilmu kesehatan secara global.
Mastitis Granulomatosa: Sebuah Tantangan Diagnosis Dewi, Citra; Amalia, Ella; Kurniawati, Nyiayu Fauziah; Maria Ulfa,, Maria Ulfa,; Pratama, Eka Putra; Murti, Krisna
Majalah Patologi Indonesia Vol. 31 No. 1, Januari 2022
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v31i1.492

Abstract

BackgroundGranulomatous mastitis (GM) is often found in reproductive-age women. These patients are treated by the administration ofantituberculosis drugs. It is difficult to determine the exact cause of GM cytologically and histopathologically. Various etiologies i.e.,tuberculosis, sarcoidosis, foreign bodies and immunological diseases may provide granulomatous inflammation features in thetissue. High-sensitivity tests such as PCR can help to detect the presence of Mycobacterium tuberculosis (MT) as one of possibleetiologic agent. Accurate diagnosis will improve the treatment quality thus a better quality of life. The aim of this study was todetermine whether the granulomatous mastitis patients who referred to the Department of Anatomic Pathology Faculty of MedicineUniversitas Sriwijaya/Dr. Moh. Hoesin Palembang Hospital were caused by MT.MethodsA descriptive observational study was performed. Thirty paraffin blocks of GM patients during the period of 1st October 2018 to 29thSeptember 2020 were collected. DNAs were extracted from tissue scrapings of the slides. Then, PCR analysis was conducted usinga specific primer IS6110 with around 200 bp PCR product.ResultsThe mean age of the patients was 40.8 years (range: 23-67 years). There were six samples (20%) of GM produced the expectedamplicon. However, only three of six samples morphologically consistent with tuberculosis.ConclusionGranulomatous inflammatory reactions in the breast are not only caused by tuberculosis. Further study is needed to determine theexact cause of this lesion. Despite high costs, PCR examination may become an alternative approach in determining the etiology ofGM.
Edukasi Perilaku Hidup Bersih dan Sehat (PHBS) di Kelompok Masyarakat Kebumen Gemilang Sejahtera Palembang Nawawi, Rizki Andini; Amalia, Ella; Rivani, Erizka; Usman, Doni; Zanaria, Rima; Saputra, Firdaus Rizky; Adzanarasta, Achmad Riezky; Natasya, Cindy; Yosita, Dilla; Humaira, Nabila Tsabitah
Abdimas Universal Vol. 8 No. 1 (2026): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v8i1.2830

Abstract

Infectious disease remains a common risk in Indonesian societies. Clean and Healthy Lifestyle (CHL) is an effort to increase community health status in various settings. Communities involved in waste management are more at risk of contracting infectious diseases. Kebumen Gemilang Sejahtera (KGS) Community is a community movement in Palembang concerned with environmental issues, which manages household waste through its community waste bank. This community service activity aimed to increase the KGS Community members’ knowledge and awareness about infectious diseases through household CHL implementation. The activity was a direct visitation and in-person health education. The activity was carried out at KGS Waste Bank, situated at Jalan Sersan Zaini No. 2819, RT. 27, Dua Ilir Village, Ilir Timur II District, Palembang. Health education was carried out with supporting interactive multimedia presentation and poster, comprising of infectious disease risks, chain of infection, symptoms of infectious diseases, and indicators of household CHL, accompanied by relevant demonstrations from the team. There was an increase in household CHL knowledge among KGS Community members, which was shown by increased average posttest score compared to pretest score.
Co-Authors ., Mariana Adzanarasta, Achmad Riezky Ahmad, Qaedi Ahmad, Zen Al-Fayed, Muhammad Sadad Ali Djamhuri Annisa Rahmawaty Ansyori, Achmad Rifky Athiah, Medina Azhari, Dalilah Beauty Novianty Citra Dewi Citra Dewi Diba, Masayu Farah Dwi Handayani Dwi Indira Setyorini Dwi Indira Setyorini Dwirini Retno Gunarti Eka Febri Zulissetiana Eka Putra Pratama Faradillah Dillah Farah Diba, Masayu Fatmawati Fenny Etrawati Gita Dwi Prasasty Hermansyah Humaira, Nabila Tsabitah Hutabarat, Yosafat Beltsazar Ika Kartika Irnanda, Andi Karim, Fatmawati Kemas Ya'kub Rahadiyanto Krisna Murti Krisna Murti Lionita, Widya Lusia Hayati Lusia Hayati, Lusia M. Hafizh Arrafi M. Nadhif Prasetyo M. Yogi Riyantama Isjoni Maghfiroh Rahayu Nindatama, Maghfiroh Rahayu Mansur, M. Syafi'i Maria Ulfa, Maria Ulfa, Maria Ulfa,, Maria Ulfa, Meilinda, Nurly Misnaniarti Misna Muhammad Irsan Saleh Muhammad Syahrul Ramadhan Natasya, Cindy Nawawi, Rizki Andini Nita Parisa Nyiayu Fauziah Kurniawati pariyana, Pariyana Pratama, Eka Putra Putra, Ramadhan Ananditia RACHMAT HIDAYAT Rahma Kurnia Lestari Rahma Nur Islami Rahmawati, Fuji Rara Inggarsih Rasyid, Riana Sari Puspita Rivani, Erizka Rizma Adlia Syakurah Sabrina, Tia Sadakata Sinulingga Safira Azahra Safyudin Saputra, Firdaus Rizky Septi Purnamasari Setyorini, Dwi Indira SRI RAHAYU Subandrate Syarifah Aini Syauki Ikhsan, Diyaz Theresy, Elzabet Tri Suciati Usman, Doni Venny Larasati Yosita, Dilla Yundari, Yundari Yuwono Yuwono Yuwono Zanaria, Rima Zefianto, Zefianto Ziske Maritska