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All Journal Tropical Medicine Journal Scriptura Jurnal Pendidikan Kimia Intuisi Journal of Mathematical and Fundamental Sciences INKUIRI : Jurnal Pendidikan IPA Jurnal SOLMA Jurnal Ilmiah Manuntung Jurnal Ilmiah Sekolah Dasar Walisongo Journal of Chemistry Jurnal Pembelajaran Sains Jurnal Inovasi Pendidikan dan Sains Panrannuangku Jurnal Pengabdian Masyarakat Student Scientific Creativity Journal Jurnal Ilmiah Pengabdian dan Inovasi Room of Civil Society Development Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Morfologi : Jurnal Ilmu Pendidikan, Bahasa, Sastra dan Budaya Bulletin of Chemical Reaction Engineering & Catalysis Indonesian Journal of Biology Education Asian Journal of Environmental Research Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Room of Civil Social Development
Dian Nugraheni
Universitas Negeri Malang
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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A Pyrone and Flavonoid Derivatives from Cryptocarya crassinervia and their Inhibitory Properties against Receptor Tyrosine Kinases Dian Nugraheni; Elvira Hermawati; Hendra Helmanto; Dikhi Firmansyah; Yana Maolana Syah; Lia Dewi Juliawaty
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 3 (2024)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2024.55.3.5

Abstract

A new a-pyrone, i.e., cryptocrassinervione (1), and a new flavone glycoside, i.e., kaempferol-3-O-rhamnosyl-2-O-apiofuranoside (4), were isolated from EtOAc extract of Cryptocarya crassinervia leaves. Along with these compounds, two known flavone glycosides, namely afzelin (2) and quercitrin (3), were also isolated. The structures of the new compounds were determined based on NMR and mass spectral data. Compounds 1–4 were examined against eight receptor tyrosine kinases (RTKs) (EGFR, HER2, HER4, IGF1R, InsR, KDR, PDGFRα, and PDGFRβ), which showed that these compounds were moderately active against EGFR, with inhibition percentages of 55, 49, 41, and 44%, respectively. They were weakly active against HER2, with inhibitions of 17, 20, 18, and 16%, respectively. However, they were not active against the rest of the RTKs. Nevertheless, compounds 1–4 have potency as inhibitors of EGFR.
The Use of Metals in the Voltaic Series and Its Implications on How Natural Batik Dye is Fixed Maghfiroh, Maghfiroh; Nugraheni, DIan; Widadi, Zahir; Murty, Daru Anggara; Fahria, Mila; Pratiwi, Novida
Walisongo Journal of Chemistry Vol 6, No 2 (2023): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v6i2.18110

Abstract

The presence of natural colorants in the batch industry supports efforts to create sustainable products. However, the disadvantage of natural coloring substance is that tissue fibers generally have a low affinity to the pigment components, so the natural colorant is easily flourishing. This fact is based on exploring natural coloring substances and the type of fixator of the corresponding natural coloring substance. In addition to strengthening the absorption of color substances into the fiber, the fixator also serves to know the direction of color produced by the natural coloring substance. In testing, fixers are used that contain metals present in voltaic series. The object of the study is to described the color characteristics produced by natural dyeing substances (secang and tegeran woods) on various types of fixers that are included in the voltaic series. Color quality is assessed from 3 aspects i.e. color intensity parameters visually, color resistance with grey scale and color direction with website coolors.co. In general, the secang wood produces the pink color (warm category) while the tegeran wood color is yellow (vintage category). There is a regular sequence of the color concentration of the fabric achieved by each voltaic series metal used as a fixer. If the metal is applied as a fixer to the natural coloring material, the stronger oxidative properties of a metal on the voltaic series, the older the resulting color will be. 
Analisis Tindak Tutur Ilokusi pada Teks Drama dalam Buku Bahasa Indonesia Kelas VIII Kurikulum 2013 Dian Nugraheni; Ulfi Akhyatussyifa; Vianni Nifattien Vrisna Putri; Putri Dzakiyyatul Khotimah; Nida Rufaida; Asep Purwo Yudi Utomo; Zulfa Fahmy
Morfologi: Jurnal Ilmu Pendidikan, Bahasa, Sastra dan Budaya Vol. 2 No. 1 (2024): Februari : Jurnal Ilmu Pendidikan, Bahasa, Sastra dan Budaya
Publisher : Asosiasi Periset Bahasa Sastra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/morfologi.v2i1.299

Abstract

This article examines drama texts that focus on pragmatic aspects, namely illocutionary speech acts. The texts studied are drama texts listed in the Indonesian Language Book Class VIII Curriculum 2013. The background of this article is based on the diversity of the application of illocutionary speech acts in the drama text. The purpose of this article is to analyze illocutionary speech acts in drama texts. The method used in this research uses a methodological approach, namely descriptive qualitative, and a theoretical approach, namely pragmatics. The data of this article consists of a group of sentences that form a paragraph taken from the drama text in the Indonesian Language Book Class VIII Curriculum 2013 and studied commensurate with the classification of illocutionary speech acts. The data source comes from the drama text in the Indonesian Language Book Class VIII Curriculum 2013. The techniques used are note-taking techniques and listening techniques or reading data which are data collection techniques. The data analysis technique in the research uses agih and padan techniques. Data presentation techniques with informal techniques. From the existing data, the conclusion is that there are several forms of speech acts in the drama text, namely: representative/assertive, expressive, commissive, directive, and declarative illocutionary speech acts contained in the drama text. This article has benefits for students because it can provide knowledge about the classification of illocutionary speech acts.
Analisis Frasa pada Buku Panduan Belajar dan Bermain Berbasis Buku untuk Pengajar PAUD Dian Nugraheni; Evi Nur Mala Sari; Putri Dzakiyyatul Khotimah; Nida Rufaida; Asep Purwo Yudi Utomo; Rossi Galih Kesuma
Student Scientific Creativity Journal Vol. 1 No. 2 (2023): Maret : Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v1i2.1695

Abstract

Phrases can start with a preposition or a verb and also can just be the subject. Phrases are in a syntactic function which is formed from a combination of words. Often found in the text in a sentence, for example, is one of which is in the Book-Based Play and Learning Guide for Early Childhood Teachers. This study discusses the analysis of the use of phrases in the textbook. The aim is to find out the relevance of the sentence study of the types of phrases contained in book-based play and study guides for early childhood teachers. This study uses a qualitative method with a descriptive approach. The data collection method uses observation techniques and examines how the language is applied, and the note-taking method is also used to record the structure being analyzed. This study found that there are 3 verb phrases, 3 adjektiva phrases, 3 numeral phrases, 3 noun phrases, 3 exocentric phrases, and 3 endocentric phrases. One of the benefits of this research is that we understand more about the types of phrases in each sentence.
The Potential of Self-Organised Learning Environment E-Module to Enhance Students' Critical Thinking Skills and Cognitive Learning Outcomes Amalia, Berlyana; Mulyati, Yayuk; Nugraheni, Dian; Habiddin, Habiddin; Annisa, Nidya; Hasan, Said; Wicaksono, Azizul
Indonesian Journal of Biology Education Vol. 7 No. 2 (2024): INDONESIAN JOURNAL OF BIOLOGY EDUCATION
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The objective of this study was to ascertain the impact of critical thinking skills on the learning outcomes of junior high school students, with the Self- Organized Learning Environment (SOLE) learning model serving as the experimental framework. The research methodology employed was quasi- experimental, with a research design of nonequivalent control group design. In this study, the experimental class was Grade 8 A Class, while the control class was Grade 8 C class. The SOLE learning model demonstrated a statistically significant effect on critical thinking skills and learning outcomes, as evidenced by the t-test results with a value of 0.05 < 0.000. The N-gain score for the SOLE learning model revealed that 51.5% of the learning outcomes were less effective, while 56.8% of the critical thinking skills were moderately effective. In contrast, the control class in the Discovery Learning learning model achieved 32.3% in learning outcomes and 38.2% in critical thinking skills, both of which were ineffective. The results of the research indicate that critical thinking skills and junior high school science learning outcomes are significantly influenced by the SOLE learning model.
Extracellular Lipase from Pseudomonas aeruginosa SB-37: Production by Solid State Fermentation, Immobilization, and Characterization Haryati, Titin; Haryono, Norman Yoshi; Nugraheni, Dian; Fatmawati, Fenti; Dewi, Alfina Kusuma; Syach, Muhammad Zahran Edlian
Bulletin of Chemical Reaction Engineering & Catalysis 2024: BCREC Volume 19 Issue 4 Year 2024 (December 2024)
Publisher : Masyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9767/bcrec.20234

Abstract

Native lipase is still promising as an industrial biocatalyst. This study aimed to investigate the production of native local lipase using solid state fermentation (SSF) methods, immobilization the lipase by Ca-alginate entrapment, and characterization based on substrate preferences. To obtain high lipase production using SSF methods, we optimized the type of agro-wastes substrates, fermentation time, oil induction percentage and volume of preculture percentage. The optimal condition for lipase production via solid-state fermentation involved a 7% (v/v) preculture of Pseudomonas aeruginosa SB-37, utilizing palm kernel meal as the substrate, supplemented with 6% (v/w) oil induction (soybean oil:tween 80 = 75:25) at 50 °C for 24 h. This gave a lypolitic activity value of 2 U/gds (gram dry weight substrates). Since the protein profile of extracellular lipase has a few protein bands, we perform direct immobilization on crude protein supernatant. Immobilization by Ca-alginate entrapment results in loading capacity and recovery activity values of 86.84% and 148%, respectively. The immobilized lipase retained 92% activity until four batch repetition and keep 40% activity at tenth batch. The highest hydrolytic activity of immobilized lipase was 0.9 U/g gel on the pNP_8 substrates. While the highest transesterification activity was observed with acetonitrile solvent and substrates of pNP_8 and isopropanol with the activity value at 0.6 U/g gel. This present study emphasized the feasibility of producing lipase as a biocatalysts using economical agro-industrial wastes and efficient immobilization using entrapment method. Copyright © 2024 by Authors, Published by BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
PKM Pemberdayaan Kader PKK Melalui Pelatihan Pembuatan Perangkap Nyamuk Berbasis UV dn Biolarvasidal dari Limbah Gadung (Dioscorea hispida) untuk Penanggulangan DBD Kusumarini, Shelly; Dian Nugraheni; Anisa Wuri Kartika; Fitroh Rafli Firdausi
Panrannuangku Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2024)
Publisher : Lembaga Penelitian dan Pengembangan Teknologi dan Rekayasa, Yayasan Ahmar Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35877/panrannuangku3536

Abstract

Nyamuk merupakan vektor utama penyakit seperti DBD, Chikungunya, dan Malaria, terutama mengancam anak-anak di Desa Karang Kembang, Kecamatan Babat, Kabupaten Lamongan, pada musim hujan pasca El Niño. Pengendalian nyamuk masih bergantung pada fogging yang kurang efektif dan merusak lingkungan. Program ini memperkenalkan perangkap nyamuk berbasis sinar UV (qiUT) dan biolarvasida dari limbah gadung (Dioscorea hispida) sebagai solusi praktis dan ramah lingkungan. Kader PKK diberdayakan untuk membuat qiUT dari botol bekas dan memproduksi biolarvasida melalui maserasi. Kegiatan ini meningkatkan kapasitas 35 kader PKK dalam pengendalian nyamuk, dengan monitoring mingguan dan identifikasi jenis nyamuk, seperti Culex sp. dan Aedes sp. Program ini juga meningkatkan kesadaran masyarakat dalam kegiatan monitoring jentik. Kombinasi qiUT dan biolarvasida terbukti efektif sebagai metode alternatif yang aplikatif dan ramah lingkungan untuk pengendalian nyamuk di skala rumah tangga.
OPTIMASI KARBOPOL DAN HPMC DALAM FORMULASI GEL ANTIJERAWAT NANOPARTIKEL EKSTRAK DAUN SIRIH (Piper betle Linn) Dwi Saryanti; Dian Nugraheni; Nisa Sindi Astuti; Natasya Intania Pertiwi
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.293

Abstract

Gel is a semisolid preparation that is clear, translucent containing active ingredients, can provide a cool effect on the skin and good spread of the skin. The use of gelling agent in gel formulations greatly affects the physical properties of the resulting gel preparations. HPMC is a gel forming material that is neutral and can form a clear gel and can maintain the viscosity of the resulting gel, while carbopol are easily dispersed in water and produce preparations with sufficient viscosity. The research conducted aims to determine the comparison of carbopol and HPMC in the optimal gel formula of betel leaf extract nanoparticles with Simplex Lattice Design method. The response used was pH, viscosity, spreadability, adhesion and antibacterial activity against Staphylococcus aureus. The results obtained by carbopol concentration of 80.9% and HPMC 19.1% was the optimal gel formula of betel leaf extract nanoparticle. Based on the verification, an insignificant difference was obtained between the predictions of the software and the results of the tests performed. This shows that the method used was valid or can be trusted.
Edukasi Gizi Seimbang melalui Media Game Nutristzil Berbasis Interactive Website di SMK Mahardhika Batujajar Salsabila, Nanda Fitria; Putri, Viola Syarwendah; Ramadhan, Miftahul Akbar; Nugraheni, Dian; Anshori, M. Wildan; Astuti, Widya
Jurnal SOLMA Vol. 13 No. 3 (2024)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v13i3.14547

Abstract

Background: The lack of knowledge regarding balanced nutrition intake in adolescents resulted in suboptimal diets. Therefore, there is a need for an educational program aimed at transforming their diet following balanced nutrition guidelines. Method: The partner of this activity is class 10 RPL 2 at SMK Mahardhika Batujajar, the number of participants is 35 people, providing education on balanced nutrition through Nutristzil, an interactive web-based game. The effectiveness of this program was evaluated through pretest and posttest results. In addition, the program also includes training in website and game development, with the expectation that teachers and students studying software engineering can develop resources for nutrition education and other topics after the program’s completion. Result: The evaluation results reveal a significant difference in knowledge before and after the program, indicating a positive response from the students. Conclusion: Behavioral change can be achieved through the establishment of new habits practiced consistently for 21 days.
The Potential of Self-Organised Learning Environment E-Module to Enhance Students' Critical Thinking Skills and Cognitive Learning Outcomes Amalia, Berlyana; Mulyati, Yayuk; Nugraheni, Dian; Habiddin, Habiddin; Annisa, Nidya; Hasan, Said; Wicaksono, Azizul
Indonesian Journal of Biology Education Vol. 7 No. 2 (2024): INDONESIAN JOURNAL OF BIOLOGY EDUCATION
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The objective of this study was to ascertain the impact of critical thinking skills on the learning outcomes of junior high school students, with the Self- Organized Learning Environment (SOLE) learning model serving as the experimental framework. The research methodology employed was quasi- experimental, with a research design of nonequivalent control group design. In this study, the experimental class was Grade 8 A Class, while the control class was Grade 8 C class. The SOLE learning model demonstrated a statistically significant effect on critical thinking skills and learning outcomes, as evidenced by the t-test results with a value of 0.05 < 0.000. The N-gain score for the SOLE learning model revealed that 51.5% of the learning outcomes were less effective, while 56.8% of the critical thinking skills were moderately effective. In contrast, the control class in the Discovery Learning learning model achieved 32.3% in learning outcomes and 38.2% in critical thinking skills, both of which were ineffective. The results of the research indicate that critical thinking skills and junior high school science learning outcomes are significantly influenced by the SOLE learning model.
Co-Authors Abraham Tiandno Witjaksono Agus Purwanto Aisyah Az-Zahro Amalia, Berlyana Anisa Wuri Kartika Annisa, Nidya Anshori, M. Wildan Arief Muttaqiin Arifin, Achmad Saiful Asep Purwo Yudi Utomo Astuti, Nisa Sindi Az-Zahro, Aisyah Az-Zahro, Fatimah Dewi, Alfina Kusuma Dikhi Firmansyah Dwi Ariani, Sri Retno Dwi Saryanti Eka Nurul Qomaliyah Elvira Hermawati Erti Hamim Erti Hamimi Evi Nur Mala Sari Fahria, Mila Fardhani, Indra Fatimah Az-Zahro Fatmawati, Fenti Fitroh Rafli Firdausi Habiddin Hanandya Rahma Dinda Destriani Hanifiyah, Fitroh Haryati, Titin Hendra Helmanto Husnayaini, Nida Ilmiatunnisa, Rahmatin Ilmiatunnisa’, Rahmatin Isnanik Juni Fitriyah Khalifatulloh Fiel&#039;ardh Kusumarini, Shelly Lia Dewi Juliawaty Lina Sinatra Wijaya Maghfiroh Maghfiroh Mahardika Agus Wijayanti Mohammad Iqbal Mabruri, Mohammad Iqbal Muhammad Fajar Marsuki Muhardjito Muhardjito Mulyani, Sri Munzil Murty, Daru Anggara Natasya Intania Pertiwi Nida Rufaida Nina Chairani Fatimah Nisa Sindi Astuti Norman Yoshi Haryono Novida Pratiwi Pertiwi, Natasya Intania Prabowo, Himawan Ganjar Praptawati, Atika Purnomo Putri Dzakiyyatul Khotimah Putri, Viola Syarwendah Ramadhan, Miftahul Akbar Rini Anggi Arista Riyanto, Obaja Eden Santosa Rizky Antika Rosita Assyifa Purba Rossi Galih Kesuma Said Hasan Salsabila, Nanda Fitria Santosa, Khalis Nadhira Saryanti, Dwi Setiawan, A. M. Shinta Permata Sari Sugiyarta Stanislaus, Sugiyarta Supargiyono - Syach, Muhammad Zahran Edlian Tri Ratnaningsih Tunazjah, Savina Ulfi Akhyatussyifa Vianni Nifattien Vrisna Putri Wicaksono, Azizul Widadi, Zahir widya astuti Wuri Wuryandani Yana Maolana Syah Yayuk Mulyati Zulfa Fahmy