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Edukasi dan Praktik Pemanfaatan Tanaman Ki Encok (Plumbago Zeylanica L.) Bagi Ibu Rumah Tangga di Kecamatan Jakabaring Palembang Purwoko, Mitayani; Hastuti, Riliani; Hartina, Nabila; Sulistiani, Taris Ade; Anzani, Tsabitah Zahra Dwi
Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Vol 9, No 3 (2025): Jurnal Pelayanan dan Pengabdian Masyarakat (PAMAS)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM Universitas Respati Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52643/pamas.v9i3.5257

Abstract

Herbal plants can be consumed or applied to the painful joints. One of the Indonesian herbal plants that is useful for relieving joint pain or gout is the Ki Encok plant (Plumbago zeylanica L.). However, there are side effects that can arise if the leaves are applied for a long time, namely causing the skin to turn black and not disappear for up to two weeks. This is also called Irritant Contact Dermatitis. The purpose of this activity is to provide education and practice on how to use Ki Encok leaves to treat joint pain and education on how to use herbal plants that are good for skin health. The output of this community service activity is an increase in participants' knowledge about the benefits of the Ki Encok plant and how to prevent skin disorders due to the use of the Ki Encok plant, as well as an increase in skills in preparing Ki Encok leaf mash and applying it to painful joints. The pre-test results showed an average score of 66.67 and the post-test results showed an average score of 86.67. There was an increase in the score of 20 points. In conclusion, providing health education on the use of herbal plants to treat gout and preventing irritant contact dermatitis due to the use of herbs can increase public knowledge. Keywords: encok leaves, contact dermatitis, joint pain
Family Roles in Overcoming Picky Eating Children and Its Effect on Childs’ Nutrition Status Antonia, As Syifa; Chairani, Liza; Fitrianti, Yuni; Purwoko, Mitayani
Indonesian Journal of Medical Anthropology Vol. 6 No. 2 (2025): Indonesian Journal of Medical Anthropology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijma.v6i2.20848

Abstract

Nutritional status is a measuring scale based on the body's condition due to food consumption or nutritional intake. Picky eating is a behavior that often occurs in preschool children, which can affect the child's nutritional status. The role of parents is very influential in overcoming picky eaters. This study aimed to understand the role of the family in overcoming picky eater behavior in children and to measure the nutritional status of children with picky eater behavior at Kindergarten X Palembang. This study was qualitative research with a phenomenological approach. The informants were mothers of picky eating children based on CEBQ criteria. The data were collected using in-depth interviews and anthropometric measurements, and the data was analyzed quantitatively. This research found that parents played a role in trying to overcome picky eater behavior in children Including restrictive guidance, pressure to eat, rewarding food consumption materially, rewarding with praise, accessibility, however, their child's picky eater behavior was not resolved, and based on the results of anthropometric measurements, most children with picky eater behavior had normal nutritional status (64.7%). In comparison, 17.64% of children experience wasted nutritional status, 11.7% are severely wasted, and 5.8% are obese.
SKRINING FUNGSI KOGNITIF DAN KADAR ASAM URAT PADA PESERTA PROLANIS KLINIK DOKTER KELUARGA Purwoko, Mitayani; Heriyanto, Mochammad Junaidy; Sulistiyani, Sulistiyani; Sriningsih, Solikah; Putra, Chendra Perdana; Gani, Rima January Putri Ridwan; Prakoso, Denny Anggoro; Novitasari, Erlina Krisdianita; Tubarad, Gladys Dwiani Tinovella; Sukarno, Rizky Triutami; Rudiyanto, Waluyo; Pandhita, Gea; Aziza, Nurita; Tursinawati, Yanuarita; Airlangga, Muhammad Perdana; Setiawan, Meddy; Romi, M. Mansyur
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 2, September 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i2.12547

Abstract

ABSTRAK Fungsi kognitif dan kadar asam urat darah lansia tidak termasuk dalam pemeriksaan wajib dalam program Prolanis. Fungsi kognitif perlu dinilai untuk memastikan bahwa peserta Prolanis tidak mengalami kemunduran fungsi kognitif. Tujuan kegiatan ini adalah untuk melakukan skrining tingkat fungsi kognitif dan kadar asam urat darah peserta Prolanis di Klinik Dokter Keluarga Fakultas Kedokteran Universitas Muhammadiyah Palembang. Kegiatan dilaksanakan dalam satu hari selama 2 jam 30 menit. Pemeriksaan fungsi kognitif dilakukan menggunakan kuesioner Mini Mental State Examination (MMSE) berbahasa Indonesia. Pemeriksaan kadar asam urat darah dilakukan menggunakan darah dari ujung jari dengan alat pemeriksa asam urat dan strip khusus. Hasil skrining menunjukkan bahwa 80,4% peserta Prolanis memiliki fungsi kognitif yang normal dan 66,7% memiliki kadar asam urat darah yang normal.   ABSTRACT Cognitive function and blood uric acid levels in the elderly are not included in the mandatory screening in the Prolanis program. Cognitive function needs to be assessed to ensure that Prolanis participants do not experience cognitive decline. The purpose of this activity was to screen the cognitive function and blood uric acid levels of Prolanis participants at the Family Physician Clinic, Faculty of Medicine, Muhammadiyah University of Palembang. The activity was carried out in one day for 2 hours and 30 minutes. Cognitive function testing was conducted using the Indonesian language Mini Mental State Examination (MMSE) questionnaire. Blood uric acid testing was performed using fingertip blood with a uric acid tester and special strips. The screening results showed that 80.4% of Prolanis participants had normal cognitive function and 66.7% had normal blood uric acid levels.
Identification of Secondary Metabolites in Ethyl Acetate Extract of Ki Encok Plant Roots (Plumbago zeylanica Linn) and In Silico Cytotoxicity Activity Purwoko, Mitayani; Mundijo, Trisnawati; Astri, Yesi; Rohani, Siti
Chimica et Natura Acta Vol 13, No 2 (2025)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v13.n2.50815

Abstract

The Ki Encok plant (Plumbago zeylanica Linn) has been extensively studied and is known to have cytotoxic activity. However, no research has yet investigated the compound content of the ethyl acetate extract from that plant. This study aims to identify the secondary metabolite content in the ethyl acetate extract of Plumbago zeylanica L. roots and to determine the potential of these secondary metabolites to bind with the Caspase-3 protein in silico. The ethyl acetate extract of Plumbago zeylanica roots was tested for its phytochemical properties and examined using GC-MS. The compounds found were then searched for their structures in Pubchem, tested in silico using the CB-Dock2 software, and evaluated for drug-likeness with SwissADME. Qualitative phytochemical tests indicate the presence of alkaloid and tannin compounds. The GC-MS test showed the presence of Plumbagin, Gamma sitosterol, and 4-ethoxybenzaldehyde. In the in silico test, docking between Gamma sitosterol, Plumbagin, and 4-ethoxybenzaldehyde with the target protein Caspase-3 has free binding energies of -8.5, -7.0, and -6.1. The Gamma sitosterol-Caspase-3 complex shows the best free-binding energy among the three ligands. Further in vitro or in vivo studies are needed to assess whether the interaction between Gamma sitosterol and Caspase-3 is inhibition or activation.
FAKTOR RISIKO KEJADIAN PNEUMONIA PADA ANAK DENGAN COVID-19 DI RUMAH SAKIT MUHAMMADIYAH PALEMBANG Pranata, Muhammad Ari; Asyik, Hadi; Purwoko, Mitayani
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 7 No 2 (2024): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

COVID-19 (Corona virus disease-19) merupakan penyakit infeksi pernafasan berat yang disebabkan oleh SARS-CoV-2 (Severe acute respiratory syndrome – Corona virus -2). COVID-19 dapat disertai pneumonia ataupun tidak. Penelitian ini bertujuan untuk mengetahui faktor yang memengaruhi kejadian pneumonia pada anak dengan COVID-19 di Rumah Sakit Muhammadiyah Palembang. Jenis penelitian yang digunakan pada penelitian ini adalah observasional analitik dengan desain penelitian cross sectional. Data penelitian diperoleh dari rekam medik. Besar sampel penelitian sebesar 126 sampel anak usia 0-17 tahun yang terkonfirmasi COVID-19 menggunakan RT-PCR yang didapatkan mengunakan teknik total sampling. Hasil uji Chi-Square menunjukkan hubungan antara faktor risiko status gizi kurang-buruk (nilai p= 0,026 dan PR= 1,693), status gizi lebih-obesitas (nilai p= 0,014; PR=2,405), usia <5 tahun (nilai p=0,000; PR= 3,688), dan jenis kelamin laki-laki (nilai p= 0,039; PR= 1,512) dengan kejadian pneumonia pada anak yang menderita COVID-19. Kesimpulan, kejadian pneumonia pada anak dengan COVID-19 dipengaruhi oleh status gizi, usia, dan jenis kelamin anak. Balita berjenis kelamin laki-laki dengan status gizi kurang atau lebih memiliki kemungkinan yang lebih besar untuk mengalami pneumonia akibat COVID-19. Kata kunci : COVID-19, faktor risiko COVID-19, pneumonia, status gizi DOI : 10.35990/mk.v7n2.p135-145
Upaya Peningkatan Imunitas Anak Karyawan Universitas Muhammadiyah Palembang dengan Vaksinasi Influenza Chairani, Liza; Purwoko, Mitayani; Wakilla, Putri
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.1949

Abstract

Influenza is a highly contagious respiratory tract disease, caused by several influenza RNA viruses. The Influenza vaccine shows a protective effect against the virus that causes COVID-19. The purpose of this activity was to increase parents' knowledge about influenza and increase children's immunity to the influenza virus. The form of activity was divided into two, namely health counseling to the parents and then followed by injecting the Influenza vaccine to the children. The health education method chosen was counseling in big class at Family Medicine Clinic, Faculty of Medicine, Universitas Muhammadiyah Palembang. Health education was preceded by a pre-test with 5 multiple choice questions and ended with a same-question post-test. The average pre-test score was 75.5 and the post-test score was 93.3. There was an increase in the score which indicates an increase in the knowledge of the parents. Of the 18 parents who attended counseling, only 6 parents allowed their children to be vaccinated. The number of children vaccinated was 11 people. The follow up showed no sign of adverse effects of Influenza vaccination on children.
Hubungan Pola Latihan Angkat Beban dengan Kejadian DelayedOnset Muscle Soreness (DOMS) pada Anggota Pusat Kebugaran X Muzakki, Muhammad Azman; Oktariza, Rury Tiara; Purwoko, Mitayani; Indriyani, Indriyani
MESINA (Medical Scientific Journal) Vol 6, No 1 (2025): Medical Scientific Journal (MESINA)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/msj.v6i1.10281

Abstract

Delayed Onset Muscle Soreness (DOMS) adalah kondisi nyeri otot yang muncul setelah aktivitas fisik yang intens (24-72 jam setelah latihan) terutama pada latihan beban dan ditandai oleh rasa nyeri, kekakuan otot, dan penurunan kekuatan otot. Salah satu faktor yang memengaruhi munculnya kondisi ini adalah pola latihan angkat beban. Tujuan penelitian ini untuk mengetahui hubungan pola latihan angkat beban dengan kejadian Delayed Onset Muscle Soreness (DOMS) pada anggota pusat kebugaran X. Penelitian merupakan penelitian observasional analitik dengan desain cross sectional. Populasi penelitian ini adalah anggota pusat kebugaran X dengan sampel sebanyak 66 orang, yang memenuhi kriteria inklusi dan eksklusi, serta didapatkan melalui purposive sampling. Data pada penelitian pola latihan  (drop set, super set, dan intraset rest) dan kejadian DOMS beserta derajat nyerinya didapatkan melalui wawancara dan formulir skala NRS. Analisis data dilakukan secara komputerisasi menggunakan uji fisher exact test dengan nilai signifikansi p<0,05. Hasil penelitian ini menunjukkan pola latihan terbanyak adalah intraset rest (39,4%), dan sebanyak (95%) responden mengalami DOMS dengan mayoritas mengalami nyeri sedang (46,4%). Terdapat hubungan yang bermakna antara pola latihan angkat beban dengan kejadian Delayed Onset Muscle Soreness (DOMS) pada responden (p=0,01; OR=8,44). Dapat disimpulkan bahwa pola latihan dapat mempengaruhi terjadinya DOMS pada mereka yang melakukan latihan angkat beban. 
SKRINING KADAR GULA, ASAM URAT, DAN KOLESTEROL DARAH MASYARAKAT DI KAMBANG IWAK PALEMBANG Purwoko, Mitayani; Baihaqi, Rafly Al; Putri, Naurah Ramadhanti Hamanda; Rahmatillah, Rirah; Khalilillah, Muhammad Thareq; Meidiana, Hesesty; Maulana, Rizky
Community Impact and Society Empowerment Journal Vol. 1 No. 1 (2025): May
Publisher : Indonesian Researchers Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Perubahan gaya hidup menjadi lebih modern menyebabkan timbulnya penyakit yang didasari oleh tingginya kadar gula darah, asam urat, dan kolesterol darah. Masalah ini timbul karena masyarakat cenderung tidak memeriksakan diri jika tidak ada keluhan sehingga penyakit baru dapat diketahui setelah kronis. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk menyaring kelainan kadar gula darah, asam urat, dan kolesterol darah masyarakat dari berbagai kalangan umur yang sedang beraktivitas di Kambang Iwak Palembang pada tanggal 27 April 2024. Metode kegiatan dilakukan dalam bentuk pemeriksaan darah di ujung jari lalu pemberian edukasi kesehatan bagi peserta dengan hasil yang tidak normal berupa konseling individu. Hasil kegiatan ini mendapatkan 16 orang memeriksa kadar gula darah, 16 orang memeriksa asam urat, dan 15 orang memeriksa kolesterol. Peserta dengan kadar gula darah tinggi sebanyak 4 orang, asam urat tinggi 4 orang, dan kolesterol darah tinggi 9 orang.
Network Pharmacology of Ki Encok (Plumbago zeylanica Linn) Plant as A Treatment for Osteoarthritis Purwoko, Mitayani; Mundijo, Trisnawati; Widyadi, Yoshiko
Chimica et Natura Acta Vol 13, No 3 (2025)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v13.n3.61349

Abstract

One of the plants in Indonesia used by the community to treat gout or Osteoarthritis (OA) is the Ki Encok plant (Plumbago zeylanica Linn). However, it is currently unknown what active substances play a role in the therapy process for gout or OA and what the pathway is. This study aimed to predict the pharmacological mechanism of the active content of Encok leaves against OA disease. This study used an in silico experimental test. The content of active plant substances was extracted from IMPPAT and KNAPSACK. Then, the target proteins of all these active substances were searched for, including target proteins involved in OA disease, through the GeneCards database. Common targets were then analyzed using the STRING database. Pathways involved in OA therapy by P. zeylanica Linn were analyzed using Gene Ontology. The active substances P. zeylanica plant are 52 components with 163 protein targets. Proteins involved in the pathogenesis of OA were found to be 5,394 proteins. Common targets were found to be 100 proteins. After being analyzed based on degree, the top 10 common targets that may play a role are ALB, TNF, INS, AKT1, TP53, IL6, PPARG, ESR1, HIF1A, and JUN. The active compounds contained in P. zeylanica with target proteins that match OA are D-glucose, vanillic acid, beta-stigmasterol, isoorientin, and lupeol.
Co-Authors -, Hasmeinah Adhi Permana Aditya Warman Aditya, Muhammad Akbar Aflah, Anisatul Ahmad Ghiffari Akrom, Muhamad Afif Al Alifah, Haura Zatty Amalda, Dea Anggina, Dientyah Nur Anggraini, Wieke Antonia, As Syifa Anzani, Tsabitah Zahra Dwi Asyik, Hadi Aziza, Nurita Azzahra, Rashieka Adawiya Baihaqi, Rafly Al Chairani, Liza Dewi Yuniasih Dian Wahyuningsih Eka Sri Yusmartini Eko Ariyanto Eriko Erenkwot Fachrozi, Muhammad Fuad Arifin fatimah Fatimah Ferzieza Dizayang Fitrianti, Yuni Franscisco, Jimmi Ghea Lingga Septiareni Gialini, Windy Ulfa Gunawan, Ernes Putra Hartina, Nabila Hasmeinah - Hasmeinah Bambang Hastuti, Riliani Heriyanto, Mochammad Junaidy Herlangga, Arya Indawaty, Septiani Nadra Indriani, M. A. Yenny Indriyani Indriyani Iqsa, Abil Jamaiyah, Miranda Khalilillah, Muhammad Thareq Lucille Anisa Suardin M. Mansyur Romi Meddy Setiawan Meidiana, Hesesty Meilina Wardhani Miranda, Mira Muhamad Ayus Astoni Muhammad Aditya Alfarizki Muhammad Nazir Muhammad Perdana Airlangga, Muhammad Perdana Mundijo, Trisnawati Mutia Mutmainnah Muzakki, Muhammad Azman Nafatilana, Dinda Ningsih, Ena Aprita Nofitasari, Camelia Novitasari, Erlina Krisdianita Nurjanah, Rizki Anisa Oktariza, Rury Tiara Pamudji, Raden Pandhita, Gea Permana, Adhi Prakoso, Denny Anggoro Pranata, Muhammad Ari Putra, Chendra Perdana Putri, Naurah Ramadhanti Hamanda Rahmatillah, Rirah Ramayanti, Indri Ratih Pratiwi Ressy Irma Juwita Reza Reza Rima January Rizki, Putri Nersi Rizky Maulana, Rizky Rodhiaty, Fera Yunita Ronnia, Ronnia Rudiyanto, Waluyo Sabrina, Siti Safitri, Oktarina Salsabilla, Rizky Salsabilla, Salsabilla Salsyah, Alya Saraswati, Nia Ayu Sheilla Yonaka Lindri Silvana, Rista Sinta, Adliah Zahira Padya Siti Rohani Sriningsih, Solikah Stiawan, Ridho Suciandari, Altiara Risky Suciandari, Altiara Risky Sukarno, Rizky Triutami Sulistiani, Taris Ade SULISTIYANI SULISTIYANI Syadra Bardiman Tubarad, Gladys Dwiani Tinovella Utami, Dhiya Luthfiyyah Wakilla, Putri Widyadi, Yoshiko Wijaya, Otchi Putri Yanuarita Tursinawati, Yanuarita Yesi Astri