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All Journal JURNAL ILMIAH KESEHATAN KEPERAWATAN Pharmaciana: Jurnal Kefarmasian Pharmacon CHEMPUBLISH JOURNAL Acta Pharmaciae Indonesia : Acta Pharm Indo PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Journal of Fundamental and Applied Pharmaceutical Science Prosiding Seminar Nasional Program Pengabdian Masyarakat Jurnal Pijar MIPA Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Jurnal Farmasi Klinik dan Sains Usadha Journal of Pharmacy Jurnal Ilmiah Kesehatan Keperawatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Journal of Pharmascience
Kiromah, Naelaz Zukhruf Wakhidatul
Program Studi Farmasi Program Sarjana, Sekolah Tinggi Ilmu Kesehatan Muhammadiyah Gombong,
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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GAMBARAN TINGKAT PENGETAHUAN PASIEN DI UPTD PUSKESMAS KUWARASAN TENTANG PRODUK OBAT HALAL Sahro, Intan Fatimah; Handayani, Eka Wuri; Widiastuti, Tri Cahyani; Kiromah, Naelaz Zukhruf Wakhidatul
Jurnal Farmasi Klinik dan Sains Vol 5, No 2 (2025): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v5i2.1845

Abstract

Kehalalan produk obat menjadi perhatian penting bagi masyarakat Muslim di Indonesia, namun dari 19.483 produk farmasi yang terdaftar di BPOM tahun 2022, hanya 13,27% yang telah bersertifikat halal. Penelitian ini bertujuan mengetahui gambaran tingkat pengetahuan pasien terhadap produk obat halal dan menganalisis hubungan antara karakteristik pasien dengan tingkat pengetahuan. Metode penelitian adalah deskriptif-analitik dengan pendekatan potong lintang pada 331 pasien yang dipilih menggunakan teknik purposive sampling. Data diperoleh melalui kuesioner yang telah diuji validitas (r > 0,361) dan reliabilitas (α = 0,912), kemudian dianalisis secara deskriptif dan bivariat menggunakan uji chi-square. Hasil penelitian menunjukkan mayoritas responden adalah perempuan (82,77%), berusia 26–40 tahun (28,7%), berpendidikan SMA (58,6%), dengan tingkat pengetahuan baik (94,56%), cukup (4,53%), dan kurang (0,91%). Analisis bivariat menunjukkan terdapat hubungan signifikan antara tingkat pendidikan (p=0,021) dan pernah mendapat informasi (p=0,001) dengan tingkat pengetahuan. Kesimpulannya, mayoritas pasien memiliki pengetahuan baik tentang produk obat halal. Diperlukan program edukasi berkelanjutan khususnya untuk kelompok dengan pendidikan rendah dan yang belum pernah mendapat informasi tentang obat halal.
Uji Aktivitas Antioksidan Menggunakan Metode DPPH (2,2-difenil-1-pikrilhidrazil) Terhadap Ekstrak Etanol Kulit Buah Durian (Durio zibethinnus L.) dari Desa Alasmalang Kabupaten Banyumas Eko Prasetyo; Naelaz Zukhruf Wakhidatul Kiromah; Titi Pudji Rahayu
Journal of Pharmascience Vol. 8 No. 1 (2021): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v8i1.9200

Abstract

Kulit durian merupakan bagian tanaman yang pernah diteliti sebelumnya dan mempunyai aktivitas farmakologi sebagai antioksidan. Kulit durian mengandung metabolit sekunder yaitu flavonoid, tanin dan alkaloid. Kulit durian diekstrak menggunakan pelarut etanol 70% dengan metode sokletasi.  Pengujian aktivitas antioksidan menggunakan metode pengukuran penangkapan radikal bebas oleh 1,1-difenil-2-pikrilhidrazil (DPPH). Vitamin C digunakan sebagai kontrol positif dengan nilai IC50 5,63 ppm dan ekstrak etanol sebesar 204,33 ppm. Penelitian ini menunjukkan bahwa ekstrak etanol kulit durian tidak memiliki aktivitas antioksidan menggunakan metode DPPH. Kata Kunci: Durian, Sokletasi, DPPH (2,2-difenil-1-pikrilhidrazil), antioksidan, IC50  Durian fruit peels (Durion zibethinus Murr.) have  been studied previously and reported to have phramacological activity that has the potential to be antioxidant. The durian fruits peels, contained secondary metabolite, namely flavonoids, tannin and alkaloid. Durian fruit peels (Durion zibethinus Murr.) were extracted with ethanol 70% with soxletation method. The antioxidant activity of extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay. Vitamin C was used as standard with IC50 5,63 ppm and the ethanol eztracts showed IC50 204,33 ppm. This study provided that Durian fruit peels (Durion zibethinus Murr.) cannot inhibit free radical usimg the DPPH method. 
Analgesic Activities of Ethanolic and Methanolic Extract of Ganitri Leaves (Elaeocarpus ganitrus Roxb): In vivo study Kiromah, Naelaz Zukhruf Wakhidatul; Miyarso, Chondrosuro; Krisdiyanti, Yayu
Journal of Fundamental and Applied Pharmaceutical Science Vol. 2 No. 1 (2021): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v2i1.12159

Abstract

Pain is a feeling of discomfort caused by intense or destructive stimuli, which can affect your daily routine if left untreated. Pain can be treated with an analgesic. One of the plants that are considered to have analgesic effects is the leaves of the ganitri. This research aims to determine ethanol and methanol extracts' impact on decreasing analgesic activity and percent protection. The study began with collecting and processing the leaves of the ganitri into the ethanol and methanol extracts using the maceration method. The research was continued with in vivo analgesic activity testing of 24 mice induced by pain using 1% acetic acid. The induced mice were divided into eight treatment groups, where the mice in the first group served as a negative control group. In that group, they were given CMC at a dose of 0.5%. The second group was positive control, given mefenamic acid at a dose of 500 mg/kg BW. In contrast, the third until eighth groups were given ethanol and methanolic extracts of the ganitri leaves with consecutive doses of 100 mg/kg BW, 200 mg/kg BW dan 400 mg/kg BW. Parameters measuring the effectiveness of the extracts used in this study included the amount of stretching, the percentage of analgesic power, and analgesic effectiveness. The results showed that the ethanolic and methanolic extract had the highest percentage of analgesic power at 400 mg/Kg BW amounted to 91,3% and 88,3%. Furthermore, based on the statistical analysis results using ANOVA, it was found that the ethanol and methanolic extracts of the leaves of the ganitri dosage of 400 mg/Kg BW had analgesic activity close to 500 mg/kg BW of mefenamic acid.
Co-Authors Afif Hussein Kholid Bahrisy agung setiawan Agung Setiawan Ainni, Ayu Nissa Arnika Dwi Asti Asriani Tagawuningsih Astri Ayu Febri Yuliani Awalia, Luluk Azhari, Tasya Khairunisa Bahrisy, Afif Hussein Kholid Billa, Zalsa Chondrosuro Miyarso Chondrosuro Miyarso Churrohmah, Syifa Condro Suro Miyarso Dwiki Fitri EkaWuri Handayani Eko Prasetyo Ery purwanti Ery Purwanti Evi Marlina Farda, Zais Fatimah, Ayu Febrialfiyan, Sukma Edhie Fiana, Fuan Maharani Fitriyati, Laeli Fuan Maharani Fiana Hamzah, Hasyrul Handayani, Eka Wuri Hasanah, Saniati Herniyatun Herniyatun, H Khobiratul Majidah Khuluk, Khusnul Khuluq, Muh Husnul Khusnul Khuluk Krisdiyanti, Yayu Kumalasari, Siska Kurniasih Kurniasih Kurniasih Kurniasih L Ledianasari L Ledianasari Laeli Fitriyati Laeli Fitriyati Laeli Fitriyati Ledianasari, L Majidah, Khobiratul Melisa, Leni Miyarso, Chondrosuro Miyarso, Condro Suro Muchromin Muchromin Muhammad Luthfi Mulyana, Satria Eta Nafarina, Eka Rezki Tri Ningsih, Eka Ratna Pamungkas, Anindya Arya Pratama, Dimas Aji pratiwi, lia nur Pratiwi, Noviani Pravitasari, Rokhania Eka Rachman Aziz, Dwinuari Rachmawati, Indah Rahayu, Titi Pudji Rahayu, Venny Septiana Rahmat Ismail Rahmawati Rahmawati Sadam Husein Sadam Husein Sadam Husein Sahro, Intan Fatimah Saputra, Aditya Mahe Sholihah, Rizka Hidayatus Sinta Wahyu Septiani Sugeng Supriyanto Supriyanto, Sugeng Tagawuningsih, Asriani Tangawuningsih, Asriani TITI PUDJI RAHAYU Titi Pudji Rahayu Titi Pudji Rahayu Tri Cahyani Widiastuti Tri Cahyani Widiastuti Tri Cahyani Widiastuti Tri Cahyani Widiastuti Uswatun Hasanah Utomo, Hijan Dzulfadhli Wahyu Rahmatulloh Widiastuti, Tri Cahyani Yayu Krisdiyanti Yayu Krisdiyanti Yusuf Kurniawan Yusuf Kurniawan Zubaidah, Siti Nur