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Lobectomy of Single Pulmonary Nodul Increased Quality of Life and Lung Function in 1 and 3 month After Surgery Susanti, Lia; Djajalaksana, Susanthy; Indah Sari, Fitri; Rachma Erawati, Dini; Setyo Yudhanto, Hendy; Kusuma Wardhana, Koernia
Malang Respiratory Journal Vol. 7 No. 2 (2025): Volume 7 No 2, September 2025 Edition
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2025.007.02.05

Abstract

Introduction: Since a single pulmonary nodule (SPN) usually doesn't cause any respiratory symptoms, it is frequently found by accident. On a chest X-ray, the incidence of SPN is 0.1-0.2%, and on a contrast-enhanced CT scan of the thorax, it is 13%. In populations at high risk, the incidence rises to 9–33%. Contrast-enhanced CT scans are essential for early detection in order to assess and choose a course of treatment. About 40–50% of SPNs are malignant, with adenocarcinoma being the most prevalent subtype, making for 47% of all instances of lung cancer. Surgical intervention is advised in the early stages. Case Report: A 62-year-old nonsmoker arrived with haemoptysis and a persistent cough. A contrast-enhanced CT scan revealed a solid lesion of 2.8 cm x 2.7 cm x 2.4 cm, classified as stage IA. A chest X-ray revealed a tiny mass measuring 1.5 cm x 1 cm. Following a lobectomy, the patient's pathology revealed Non-Small Cell Lung Carcinoma (NSCLC), specifically adenocarcinoma. To rule out organ metastases, immunohistochemistry (IHC) assays were used. Conclusion: Lobectomy for SPN adenocarcinoma stage IA improves lung function and quality of life at one and three months post-surgery.
Rare Case : Lymphangioleiomyomatosis in a 28 year-old woman with spontaneous bilateral pneumothorax Matabei, Shannon Conversia Pdabo; Djajalaksana, Susanthy; Chozin, Iin; Erawati, Dini; Wardhana, Koernia; Yudhanto, Hendy; Rahman, Perdana; Chen, Chung-Yu
Malang Respiratory Journal Vol. 7 No. 2 (2025): Volume 7 No 2, September 2025 Edition
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2025.007.02.04

Abstract

Introduction: Lymphangioleiomyomatosis (LAM) is an extremely rare disease with no known exact cause, in which there are abnormalities in the development of smooth muscle cells. This condition manifests in multiple organs, one of which is the lungs. Prevalence of LAM is 1 in 1,000,000, most commonly found in women of reproductive age. Pneumothorax occurs in two-thirds of LAM patients. It is possibly underdiagnosed in Indonesia. Case report: A 28-year-old woman came to the Emergency Department with sudden severe shortness of breath. Chest X-ray shows bilateral pneumothorax predominantly on the left side, and a chest tube was installed. Thorax MSCT revealed multiple cysts in all areas of lungs, while abdominal USG and MRI discovered masses in uterus and right adrenal. Left bullectomy-thoracotomy and lung biopsy were performed, with histopathology result supporting LAM. The patient was stable post surgery. LAM is associated with mutations in TSC1 or TSC2 genes, resulting in cystic changes caused by LAM cells proliferation in the lungs. In this patient, bilateral pneumothorax resulted from multiple subpleural cysts which eventually ruptured. Diagnosis of LAM was established by radiological imaging and lung biopsy. Surgical and non-surgical interventions were performed to address the acute manifestations of LAM. Unfortunately, Sirolimus which is the recommended long-term medication for LAM is not yet available in Indonesia. Conclusion: LAM is a rare disease. It’s important for clinicians to be familiar with this condition, aware of its progression and possible recurrence of pneumothorax, in order to provide appropriate interventions.
CPET : Gambaran Umum dan Penggunaan pada Pasien Gagal Jantung Suprapta, Aloysius; Listyoko, Aditya; Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 1 No 2 (2022): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.01.2.5

Abstract

Cardiopulmonary exercise test (CPET) is a non-invasive modality used to assess a person's exercise capacity. An assessment of the gas exchange mechanism that occurs in the breath-to-breath stage of respiration will describe gas exchange at the cellular level. Monitoring of gas exchange is a parameter in assessing abnormalities that cause disruption of aerobic metabolic processes in the body. These parameters in CPET assist clinicians in sorting and assessing the factors that cause dyspnea or fatigue during activity, whether disorders on the respiratory system, cardiovascular system, or muskuloskeletal side. In addition, CPET is also a modality in determining the prognosis and feasibility of heart transplantation in clients with heart failure. Peak VO2 assessment 14 mL/kg/min gave a better picture of cumulative survival in heart failure patients, and O2 pulse 10 mL/beat showed better event-free survival.
Eliminasi TB di Era Pandemi Covid yang Belum Usai Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 1 No 3 (2022): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.01.3.1

Abstract

Pencegahan COVID-19 di Panti dan Pondok melalui Pendidikan dan Perilaku Hidup yang Bersih dan Sehat Muhammad, Iqbal; Putra, Ngakan; Djajalaksana, Susanthy; Sari, Fitri; Falyani , Silvy; Yusdianto, Adrian; Fahmi, Kristia
Jurnal Klinik dan Riset Kesehatan Vol 2 No 2 (2023): Februari 2023
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.2.2

Abstract

Pendahuluan: Penyakit COVID-19 sebagai sumber penularan yang cepat dan telah menjadi pandemi di dunia dan menjadi perhatian penting terutama terhadap populasi rentan seperti anak-anak. Munculnya varian dari virus penyebab penyakit COVID-19 ini pun menjadi ancaman terutama anak-anak, dimana varian delta ditemukan dapat menginfeksi anak yang berusia diantara 1 hingga 14 tahun. Perilaku Hidup Bersih dan Sehat (PHBS) salah satu cara untuk mencegah penyebaran penyakit COVID-19 dan dapat dipraktekan untuk semua kalangan masyarakat, termasuk anak-anak. Tujuan: Penelitian ini bertujuan untuk mencari tingkat keefektivan pendidikan PHBS untuk mencegah COVID-19 pada anak-anak di Panti dan Pondok Kota Malang. Metode: Metode penelitian dengan metode kaji tindak (Action Research) dengan pendekatan program aksi partisipatif (Partisipatory Action Program) pre-test dan post-test yang melibatkan kelompok masyarakat sasaran yaitu 65 orang anak-anak di panti dan pondok Kota Malang. Data dikumpulkan melalui kuesioner yang dilaksanakan sebelum dan setelah penyuluhan berupa edukasi PHBS sebagai pencegahan COVID-19 serta data diolah menggunakan SPSS. Hasil: Hasil penelitian ini adalah terdapat peningkatan pengetahuan responden dimana nilai rata-rata sebelum penyuluhan adalah 85.08 dan meningkat sebesar 94.15 setelah penyuluhan, hasil tersebut berbeda secara signifikan dengan p-value <0.05. Kesimpulan: Terdapat perbedaan signifikan tingkat pengetahuan terhadap PHBS sebagai pencegahan COVID-19 sebelum dan sesudah dilakukan penyuluhan pada anak-anak yatim piatu di panti asuhan. Kata Kunci: PHBS; COVID-19; Edukasi; Pencegahan; Panti dan Pondok.
Analisis Pengaruh Obesitas pada Derajat Keparahan Pasien Covid-19 Gelombang ke-2 yang Dirawat Inap di RSUD Dr. Saiful Anwar Malang Djajalakasana, Susanthy; Cendani, Wulan; Djajalaksana, Susanthy; Santosa, I
Jurnal Klinik dan Riset Kesehatan Vol 3 No 3 (2024): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.03.3.3

Abstract

Background : Based on WHO data, Covid-19 has officially been declared a pandemic because its spread has reached more than 100 infected countries. Several risk factors can affect the severity of Covid-19 patients, one of which is comorbid obesity. The Covid-19 pandemic occurred when the prevalence of overweight/obesity was increasing in almost every country in the world. Chronic inflammation associated with obesity, impaired immune function, and increased expression of ACE 2 contribute to disease severity and worsen clinical outcomes in obese patients with Covid-19 infection. Aim : This study aims to analyse the effect of obesity on the severity of the second wave of Covid-19 patients who were hospitalized at RSUD dr. Saiful Anwar Malang. Methods : This research is an analytic observational study with cross sectional approach. The sample consisted of 46 Covid-19 patients with obesity who were hospitalized at RSUD dr. Saiful Anwar Malng. The data acquired will be analysed using Mann Whitney non-parametric analysis test. Results : In the obese and non-pbese groups, the p-value was 0,042 and the odds ratio was 1,23. In the distribution of age and sex groups, each group obtained a p-value of 0,363 and 0,592. Conclusion : There is a significant difference in obesity among patients, with a 1,23-fold increased risk of experiencing severity compared to those who are not obese. Meanwhile, for the distribution based on age and sex, there was no significant difference, but it tended to have a more critical degree of severity towards men and older age.
PERAN TELENUTRISI PADA PENYAKIT KRONIS DAN DIET YANG BAIK Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 2 No 3 (2023): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.3.1

Abstract

Penyakit Menular vs Penyakit Tidak Menular Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 3 No 3 (2024): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.03.3.1

Abstract

Wujudkan Generasi Bebas Rokok Djajalaksana, Susanthy
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.1

Abstract

Rancang Bangun Aplikasi Pengukur Kesehatan Fungsi Paru Manusia Memanfaatkan Microphone Pada Smartphone Kusuma, Wahyu Teja; Pramukantoro, Eko Sakti; Djajalaksana, Susanthy
Jurnal Teknologi Informasi dan Ilmu Komputer Vol 3 No 2: Juni 2016
Publisher : Fakultas Ilmu Komputer, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1164.126 KB) | DOI: 10.25126/jtiik.201632175

Abstract

ABSTRAKPenyakit Paru Obstruktif Kronik (PPOK) adalah penyakit yang ditandai dengan hambatan aliran udara di saluran nafas yang tidak sepenuhnya reversibel. Hambatan aliran udara ini bersifat progresif dan berhubungan degan respon inflamasi paru terhadap partikel gas beracun atau berbahaya [2][16]. Hasil penelitian pada bulan Januari-Desember 2010 menyebutkan bahwa PPOK menduduki urutan ke-3 dari penyakit paru terbanyak yang ada di RS Paru Batu Malang. Sedangkan di  RSU Dr. Saiful Anwar Malang  menduduki urutan ke-5. The Burden Of Disease Study dibawah naungan WHO menyatakan bahwa pada tahun 2030 PPOK akan menempati peringkat ke-3 penyebab kematian di dunia [5][15][16]. Sebagai solusi terhadap masalah tersebut yaitu dengan membangun sebuah aplikasi pengukur kesehatan  fungsi paru manusia memanfaatkan microphone pada smartphone”. Guna mengetahui gangguan ventilasi paru, monitoring pengobatan, dan menilai perkembangan fungsi paru. Media smartphone dipilih karena memiliki teknologi Microphone API yang digunakan untuk menangkap input berupa rekaman suara hembusan napas pengguna. Dan mayoritas masyarakat telah melilikinya. Dari hasil pengujian validasi dapat disimpulkan bahwa aplikasi pengukur kesehatan paru manusia pada media smartphone berhasil diimplementasikan dengan memanfaatkan teknologi microphone. Dari hasil pengujian akurasi yang dilaksanakan di Rumah Sakit Saiful Anwar Kota Malang dapat disimpulkan bahwa ditemukan selisih akurasi Prediksi Nilai Acuan Normal sebesar FEV1 = 0,11 liter; FVC = 0,152432432 liter; FEV1/FVC = 4,742432432 %. Dan selisih akurasi Hasil Pengukuran sebesar FEV1 = -1,545945946 liter; FVC = -2,892432432 liter; FEV1/FVC = 11,52243243 %.Kata Kunci: Penyakit Paru Obstruktif Kronik, Microphone, Smartphone. ABSTRACTChronic Obstructive Pulmonary Disease (COPD) is a disease characterized by air flow resistance in the airway that is not fully reversible. This air flow resistance is progressive and, relating to pulmonary inflammatory response to toxic gases or dangerous particles [2] [16]. The results of the study in January-December 2010 states that COPD ranks 3rd from most existing lung disease Pulmonary Hospital Batu Malang. Meanwhile, in Hospital Dr Saiful Anwar-5 ranks. The Burden Of Disease Study under the auspices of the WHO stated that by 2030 COPD will be ranked as the third leading cause of death in the world [5] [15] [16]. As a solution to these problems is to build an application measuring the health of human lung function utilizing a microphone on a smartphone ". In order to determine pulmonary ventilation disorders, treatment monitoring, and assessing the development of lung function. Media Smartphone Microphone technology chosen because it has an API that is used to capture the input of the user breath sound recordings. And the majority of people have melilikinya. From the results of the validation testing can be concluded that the application of measuring the health of the human lung on a smartphone media successfully implemented by utilizing the microphone. Accuracy of test results conducted at Saiful Anwar Hospital Malang can be concluded that the prediction accuracy differences were found Normal Reference Values for FEV 1 = 0.11 liters; FVC = 0.152432432 liters; FEV 1 / FVC = 4.742432432%. And the difference in the accuracy of measurement results for FEV1 = -1.545945946 liter; FVC = -2.892432432 liter; FEV 1 / FVC = 11.52243243%.Keyword: Chronic Obstructive Pulmonary Disease, Microphone, Smartphone.
Co-Authors Afif, Zamroni Anggraeni, Rizki Diah Arif Setiawansyah Arinto Wardoyo Arinto Yudi Ponco Wardoyo Bal’afif, Farhad Bayuadi, Imam Cendani, Wulan Chen, Chung-Yu Chozin, Iin Chozin, Iin Nur Christanto, Anthony Dewi Santosaningsih Dini Rachma Erawati Dini, Zata Djajalakasana, Susanthy Edwin Widodo Eka Pratiwi Eka Pratiwi Eko Sakti Pramukantoro, Eko Sakti Erawati, Dini Fahmi, Kristia Falyani , Silvy Falyani, Silvy Falyani, Silvy Amalia Febriawati, Juwita Fitri Indah Sari Fitri Sari, Fitri Harun Al Rasyid Indah Sari, Fitri Indrastuti Normahayu, Indrastuti Iqbal Muhammad Irfan, Ferdy Syah Isharanto, Artono Kristiani, Maria Kusuma Wardhana, Koernia Kusworini Handono Listyoko, Aditya Listyoko, Aditya Sri Lyono, Albert Mafisah, Saidah Mahendra, Reza Aditya Matabei, Shannon Conversia Pdabo Michaela, Cleine Muarif, Husnul Nanik Setijowati Nurdiana Nurdiana Okta, Shinta Permana, Deden Permatasari, Adinda Pramitra Prasetya, Fahmi Adhi Prasetyo, Kevin Pratiwi, Suryanti Pratiwi, Suryanti Dwi Priyono, Riski Irawan Putra Putra, Ngakan Putra, Ngakan Putu Parsama Rahman, Perdana Rakhma , Sastia Rakhma, Sastia Ramadhan, Fitratul Retnani, Diah Prabawati Safrina Dewi Ratnaningrum, Safrina Dewi santony, Santony Santosa, Andrew Santosa, I Setiadi, Satya Setyawan, Ungky Setyawan, Ungky Agus Setyo Yudhanto, Hendy Siregar, Marsintauli Hasudungan Sugiri, Yani Jane Sugiri, Yani Jane Rosihaningsih Suprapta, Aloysius Suryaman, Rachmat Susanti, Lia Suwandi, Gede Sasmika Tantular, Rezki Timuda, Caesar Ensang Tjahyadi, Rizal Muldani Tri Wahju Astuti, Tri Wahju triandani, Ni Komang Revina Triwahju Astuti Wahyu Tejakusuma, Wahyu Wardhana, Koernia Wardoyo, Arinto Yudi Pomco Yaman, Muli Yudhanto, Hendy Yudhanto, Hendy Setyo Yusdianto, Adrian