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Journal : Pharmacoscript

COST-EFFECTIVENESS DEXKETOPROFEN VS KETOROLAC IN CAESAREAN PATIENTS AT 'X' HOSPITAL, PANDEGLANG Yusransyah, Yusransyah; Sofi Nurmay, Stiani; Farahdina, Chairani; Latifah Nur, Rizki; Baha, Udin
Pharmacoscript Vol. 8 No. 2 (2025): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v8i2.2150

Abstract

Post-cesarean section pain must be treated promptly and appropriately to prevent chronic conditions. Dexketoprofen and Ketorolac are non-narcotic analgesics commonly used to manage such pain. This study aimed to analyse the cost-effectiveness of dexketoprofen and ketorolac in patients undergoing cesarean sections at Mother and Child Hospital "X" in Pandeglang. The study used a cross-sectional design with cost-effectiveness analysis, specifically the Average Cost-Effectiveness Ratio (ACER). Pain intensity was measured one hour after surgery using the Faces Pain Rating Scale and Visual Analog Scale (VAS). Inclusion criteria were patients who underwent cesarean section and received non-narcotic analgesics. A total of 90 patients participated: 39 in the dexketoprofen group and 51 in the ketorolac group. Data were analyzed using ACER and the Mann-Whitney test. The ACER, based on the Faces Pain Rating Scale, showed a cost of IDR 1,142 for the dexketoprofen group and IDR 958.03 for the ketorolac group. Using the VAS, the cost was IDR 1,110 for dexketoprofen and IDR 657.45 for ketorolac. Statistical results showed a p-value < 0.05 for both pain measurement tools, indicating a significant difference in effectiveness between the two therapies. Based on both instruments, ketorolac was more cost-effective than dexketoprofen in managing post-cesarean section pain. This finding suggests that ketorolac may be a preferable option in clinical settings where cost and effectiveness are key considerations for post-operative analgesia in cesarean section patients.
FORMULATION AND ANTIBACTERIAL ACTIVITY OF LIQUID SOAP FROM KECOMBRANG STEM EXTRACT (Etlingera elatior) AGAINST Staphylococcus aureus Syilvi, Adini; Miftah, Miftah; Yusransyah, Yusransyah; Sofi Nurmay, Stiani
Pharmacoscript Vol. 9 No. 1 (2026): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v9i1.2261

Abstract

Kecombrang (Etlingera elatior) is a plant used by the Baduy ethnic group as a substitute for soap to cleanse the skin and exhibit antibacterial activity. Staphylococcus aureus is the cause of skin infections. Liquid soap is a type of soap that can protect the skin against microorganisms, generally caused by S. aureus. This study aims to develop an antibacterial liquid soap containing kecombrang stem extract, in accordance with the quality requirements of liquid soap, and to determine its antibacterial activity against S. aureus. The extract is formulated into four liquid soap formulas, namely F0, F1, F2, and F3. Physical evaluations include organoleptic properties, homogeneity, pH, liquid soap foam height, viscosity, free alkali content, specific gravity, and antibacterial tests using the well diffusion method. In the organoleptic test, the liquid preparation is brown and has a distinctive odor, with a pH value of around 10.61 to 10.85. The foam height ranges from 33 to 93 mm, viscosity is 412 to 489 cP, specific gravity is 1.02 to 1.08, and free alkali content is 0.05 to 0.16%. Liquid soap with ethanol extract from kecombrang stem inhibits the growth of S. aureus bacteria, with inhibition zones of 9.2 mm for F1, 14.8 mm for F2, and 16 mm for F3, all with p-values <0.05. All formulas met the quality requirements for liquid soap, and F3 (17% extract) demonstrated the highest antibacterial activity.
Co-Authors Achmad Fudholi Ade Anwar Ade Apriliani Adini, Syilvi Aditia Saeffurrohman Afifah Nur Shobah Afifah Nur Shobah Afifah Nur Shobah Agnes Syafera Agus Sulaeman Anas Subarnas Andri Harpan Anjani, Shabrina Talitha Apriliani, Ade Ashari, Elva Febri Audy Nursifa'atun Aufalya Wibirezkina Aulia, Ayu Ayuni, Eka Sirly Baha Udin Cahya, Wulan Candra Junaedi Chairani, Farahdina Dewi Intan Sri Rahayu Deya Adiby Nabillah Dharojatul Khasfah Effendi, Erwin Elfrida Ratnawati Endah Endah endah, endah Endi Muchyar Eneng Elda Ernawati Eneng Elda Ernawati Fajrin Noviyanto Fajrin Noviyanto Fajrin Noviyanto, Fajrin Farahdina, Chairani Fathiyati Fathiyati Fauzi, Andrian Maulana Fauzy, Adrian Maulana Ferdiyansyah, Ferdiyansyah Fifih Lutfiyah Ghina Annufus Hanifah Dwi Safitri Harpan, Andri Hasanah, Indah Ayu Nur Hayati, Farida Herawati, Fera Indriatmoko, Dimas Danang Ismiyati, Renditya Kelutur, Faruk Jayanto Kholifah, Eva Kuncoro, Banu Kurnia, Nia Marlina Latifah Nur, Rizki Leni Halimatusyadiah Lidiah, Mae Lutfiyah, Fifih Maharani, Sylvianti Maharani, Zahra Citra Marlina, Nia Masfuah, Imas Megawati, Sefi Meila Pertiwi Miftah Miftah, Miftah Mohammad Rizal Mohammad Rizal, Mohammad Muhamad Ichsan Fahlevy Nabillah, Deya Adiby Nasiti, Febriane Dwi Neneng Nasliah Nia Marlina Nita Rusdiana S.Farm., M.Sc, Apt Nur Shobah, Afifah Nurani, Agnes Wieanita Nurhayati, Ghina Siti Nurhikmah, Ihda Nurul Fitri, Nabila Ofsah, Olin Najilah Oktaviana Hadi, Agriyaningsih Perdi, Perdi Pratiwi, Linda Rani Pratiwi, Rossi Putri, Nabila Septiani Rahmawida Putri Renditya Ismiyati Renditya Ismiyati Renditya Ismiyati Rini Rumantir Ristiani, Yuanisa Rizkiana, Muhammad Dinta Rustiyani, Risa Sabilla, Aliffia Nur Saeffurrohman, Aditia Salsabillah, Audy Nursifa'atun Satibi . Seira, Trisya Selviani, Astri Septina Sumantri, Aulia Shabrina Talitha Anjani Shirly Kumala Shobah, Afifah Nur Siska Purnama Sari Siswa Setyahadi Siti Lailatu Zahroh Siti Marina Subchan, Mohamad Suci Nurainun Sumarlin US Sumarlin US Syifa Maulidia Rizqi Syilvi Adini Sylvi Addini Sylvianti Maharani Taofik Rusdiana US, Sumarlin Wibirezkina, Aufalya Yulistina, Isti Yusransyah, Yusransyah Zahroh, Siti Lailatu