Claim Missing Document
Check
Articles

Found 33 Documents
Search

Antidiarrhea Activity of Ethanol Extract of Rambutan Leaves (Nephelium lappaceum L.) in Capsule Form on Male Mice Nurul Fadilah, Nitya; Ali Nofriyaldi; Ayu Rahmawati; Srie Rezeki Nur Endah; Widya Nurul Aini; Vincent O. Imieje
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 3 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i32024.291-297

Abstract

Background: Diarrhea is characterized by changes in stool form to soft or liquid, with an intensity of bowel movements more than three times a day. One of the plants used as an alternative treatment for diarrhea is rambutan, particularly its leaves. Previous studies have shown that rambutan leaf extract can treat diarrhea. Objective: The purpose of this study was to determine the antidiarrhea activity of ethanol extracts of rambutan leaves containing tannins and flavonoids that inhibit intestinal motility. Methods: This study was conducted experimentally using the intestinal transit method, which measures the length of the intestine passed through a marker. The smaller the ratio between the length of the intestine and the marker, the greater the decrease in intestinal motility in the mice. Group 1: loperamide HCl at a dose of 4 mg/kg BW; Group 2:  placebo; Group 3: FI, FII, and FIII capsules at doses of 50 mg, 100 mg, and 150 mg. Results: The test results showed that Formulations 1, 2, and 3 had activities of 23.3%, 26.8%, and 32.3%, respectively. The capsule with the best results was formulation 3, at a dose of 150 mg. Compared with the positive control, the effectiveness of this capsule was 22% higher than that of loperamide. Conclusion: The results of this study showed that rambutan leaves extracted in capsule form effectively treats diarrhea. The one-way ANOVA test showed a significant difference between the FI, FII, and FIII groups (p <0.05).
Pemberdayaan Perempuan Berbasis UMKM Desa Melalui Pelatihan Buket Ayu Rahmawati; Muhammad Nur Zakia; Elysa Eka; Nilama Wadnaty; Maya Rida Us Alifah; Apriyana Triwulan; Wilda Prasetya; Esa Mahesa; Arvyndho Derra; Yulika Wati; Endang Lestari; Maulida Nur; Yanto; Prasiska Kholidya; Ulfa Lailatul; Nola Fitri; Nggulam Zakia
JURNAL PENGABDIAN KEPADA MASYARAKAT Spesial Issue Oktober 2024
Publisher : LPPM UNINUS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30999/jpkm.v14i2.3431

Abstract

Menjamurnya UMKM desa salah satunya juga dilatarbelakangi dengan keberadaan wisata Embung Kuniran yang ada di Desa Kuniran, Kecamatan Sine, Kabupaten Ngawi, Provinsi Jawa Timur. Dimana pelaku UMKM bersaing dengan kemajuan teknologi, persaingan pasar domestik, dan bahkan bersaing dengan produk luar negeri. Adanya UMKM desa yang menyinergikan perekonomian dan potensi wisata awalnya membawa banyak perubahan dalam perekonomian masyarakat desa KUniran. Namun setelah kehilangan potensi wisata, maka salah satu kebangkitan para pemilik produk UMKM diantaranya adalah dengan mengembangkan inovasi dalam memasarkan produk yang dimiliki. Sehingga pelatihan buket berbasis UMKM dilaksanakan dengan maksud melatih ketrampilan atau potensi yang dimiliki oleh pemilik produk UMKM dengan cara memberdayakan perempuan-perampuan pelaku UMKM.
Pengaruh Kompetensi Karyawan Dan Beban Kerja Karyawan Terhadap Kinerja Karyawan Pada PT. Permodalan Nasional Madani Cabang Bogor Ayu Rahmawati; Widhi Wicaksono
JURNAL AKADEMIK EKONOMI DAN MANAJEMEN Vol. 2 No. 1 (2025): JURNAL AKADEMIK EKONOMI DAN MANAJEMEN 
Publisher : CV. KAMPUS AKADEMIK PUBLISING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61722/jaem.v2i1.4106

Abstract

Business competition which is currently quite tight gives demands on companies and employees to be able to maintain their business, this can also have an impact on employee workload and the need for competent employees. The purpose of this study was to determine the partial and simultaneous effects of employee competence and employee workload on employee performance at PT Permodalan Nasional Madani Bogor branch. The research method used is descriptive with a quantitative approach with a population and sample of 65 respondents, data analysis using validity test, reliability test, classical assumption test, regression analysis, correlation coefficient analysis, determination coefficient analysis, and hypothesis testing. The results of this study indicate that employee competence (X1) and employee workload (X2) affect employee performance (Y).
Edukasi Pencegahan Penularan Covid-19 Melalui Pembagian Masker Dan Hand Sanitizer Di SDN 2 Padamulya Kabupaten Ciamis Ayu Rahmawati; Teguh Ikhlas Ramadhan; Ade Rizki Nurmayadi
Sejahtera: Jurnal Inspirasi Mengabdi Untuk Negeri Vol. 2 No. 4 (2023): Oktober : Jurnal Inspirasi Mengabdi Untuk Negeri
Publisher : Universitas Maritim AMNI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58192/sejahtera.v2i4.1327

Abstract

Covid-19 is an acute respiratory disease caused by a new type of corona virus. This disease first broke out in Wuhan, China and then spread to almost the entire world and caused a global pandemic. The main symptoms of Covid-19 disease include cough, fever and shortness of breath. The Covid-19 pandemic has brought changes to various aspects of life, one of which is social change. One form of social change that occurred amid the Covid-19 pandemic was the birth of a new normal era. This new lifestyle allows all activities to resume but by implementing strict health protocols. This is the government's effort to keep all activities moving but also continue to try to break the chain of transmission of Covid-19. The purpose of this community service is to improve health status and provide education regarding steps to prevent Covid-19 in the school environment. The method used in this research is descriptive qualitative method. Based on the program, this activity also appealed to all students, teachers and school principals about Clean and Healthy Lifestyles (PHBS) and Hand Washing with Soap (CTPS), using masks and hand sanitizers. To prevent and anticipate the spread of the Covid-19 virus, public awareness is needed to actively implement PHBS and CTPS.
Evaluasi Penggunaan Obat Anti Hipertensi Pada Pasien Stroke Iskemik Di Rsud Arifin Achmad Tahun 2022 Nawwar Irfan; Nursyafni; Ayu Rahmawati; Mestika, Diani
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antihypertensive drugs are one of the drugs most commonly given to ischemic stroke patients. Ischemic stroke is a stroke resulting from thrombosis or embolism that occurs in the cerebral blood vessels and causes obstruction of cerebral blood flow to the cerebral blood vessels. The use of drugs is rational if the patient receives treatment according to his clinical needs. The aim of this study was to determine the appropriate use of antihypertensive drugs in ischemic stroke patients based on the right indication, selection of the right drug, right dose and determine the relationship between sociodemographics and the results of antihypertensive treatment in ischemic stroke patients at Arifin Achmad Regional Hospital. The method used in this research is a descriptive observational method using retrospective data which was carried out by recording medical record data of patients with a final diagnosis of ischemic stroke accompanied by hypertension with a sample size of 80 patients. people (52.5%), 45-64 years old 44 people (55%), working patients 53 people (66.3%), and the most widely used drug class was amlodipine as many as 67 people (56.8%). In the results of the chi-square test with a significance value of p value = 0.05 for the relationship between age and gender on risk factors, the age value was p = 0.004, while the gender value was p = 0.014. It was concluded that the evaluation of the use of antihypertensive drugs at Arifin Achmad Hospital was 100% correct and showed that age and risk factors were related, and gender and risk factors were related. Keywords: Hypertension, ischemic stroke, evaluation of drug use
Evaluasi Penggunaan Obat Antihipertensi Primer Pasien Lanjut Usia Periode Januari – Juni 2022 Di Puskesmas Minas Ayu Rahmawati; Dewi Gulyla Hari; nisa, Annisa Nurul Maharani
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hipertensi adalah keadaan seseorang yang mengalami peningkatan tekanan darah di atas normal, yaitu tekanan darah sistolik ≥ 140 mmHg dan atau tekanan darah diastolik ≥ 90 mmHg. Tujuan penelitian ini adalah untuk mengetahui ketepatan penggunaan obat antihipertensi primer dan hubungan Sosiodemografi terhadap hasil pengobatan pasien di Puskesmas Minas periode januari – juni tahun 2022. Metode yang digunakan adalah metode deskriptif dengan rancangan non ekperimental. Data penelitian diperoleh dari berkas catatan medik yang dikumpulkan dengan teknik pengumpulan secara purposive sampling dengan jumlah sampel sebanyak 110 pasien yang berusia lanjut. Pada hasil penelitian ini menunjukkan data karakteristik pasien yang paling banyak yaitu jenis kelamin perempuan sebesar 69 orang (62,7%), kelompok usia 45-59 tahun 53 orang (48,2%), pasien yang tidak bekerja 81 orang (73,6), dan golongan obat yang banyak digunakan yaitu amblodipin sebesar 107 pasien (97,2%). Pada hasil uji chi-square dengan nilai kemaknaan p value = 0,05 terhadap hubungan umur dan jenis kelamin terhadap faktor resiko didapatkan nilai umur adalah p = 0,873 sedangkan jenis kelamin memiliki nilai p = 0,000. Disimpulkan bahwa evaluasi penggunaan obat antihipertensi di Puskesmas Minas sudah 100% tepat dan menunjukkan bahwa umur dengan faktor resiko tidak memeliki hubungan, sedangkan jenis kelamin dengan faktor resiko memeliki hubungan. Untuk penelitian lebih lanjut diharapkan dapat melakukan observasi terhadap 2 tempat atau lebih sebagai pembanding untuk hasil yang lebih bervariatif.
Evaluasi Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Primer Rawat Jalan Lanjut Usia Periode Januari 2022 – Juli 2023 Di RSUD Arifin Achmad Provinsi Riau Nawwar Irfan; Ayu Rahmawati; Nurbaiti; Aulia Fitri, Windy
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension is a condition where the increase in systolic blood is above the normal limit, which is more than 140 mmHg and diastolic blood pressure is more than 90 mmHg. The purpose of this study was to determine the sociodemographic relationship to the treatment outcomes of hypertensive patients and to examine patterns of antihypertensive drug use at Arifin Achmad Hospital, Riau Province. The method used in this study was an observational descriptive method using retrospective data which was carried out by recording medical record data and the research subjects used in this study were outpatients with a diagnosis of hypertension with a total sample of 90 elderly patients. The results of this study showed that the most data on patient characteristics, namely female sex, amounted to 66 people (73.3%) and the most widely used drug class, namely amlodipine, was 76 patients (62.3%). On the results of the chi-square test with a significance value of p value = 0.05 for the relationship between age and gender for risk factors, the age value was p = 0.123 while gender had a p value = 0.000. It was concluded that the evaluation of antihypertensive drugs was 100% correct and showed that age and risk factors had no relationship, while gender had a relationship with risk factors.
Potensi Aktivitas Ekstrak Etanol Daun Pucuk Merah (Syzygium myrtifolium Walp.) sebagai Antihiperurisemia pada Mencit Putih (Mus musculus) Lusi Indriani; Ayu Rahmawati; Nursyafni; Nawwar Irfan; Novita Sari
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hyperuricemia is a condition where uric acid production increases or the kidneys cannot remove uric acid from the body so that uric acid levels in the blood exceed 7.0 mg/dL in men and 6.0 mg/dL in women. One of the secondary metabolites that have the potential to act as anti-hyperuricemia is flavonoids. Red shoots contain flavonoids, alkaloids, terpenoids, chalcones, and tannins. This study aimed to determine the anti-hyperuricemia activity of ethanol extract of red shoots (Syzygium myrtifolium Walp.) in white mice. This study used 16 male white mice which were randomly divided into 4 treatment groups. Group 1 was negative control (Na-CMC 0.5%), group 2 was positive control (allopurinol 300 mg/KgBW), group 3 was dose 1 (pucuk merah ethanol extract 10 mg/kgBW), and group 4 was dose 2 (pucuk merah ethanol extract 15 mg/KgBW). Before giving treatment, mice were first induced with KBrO3 at a dose of 148 mg/KgBW intraperitoneally and initial uric acid levels were measured. Then each group was given oral treatment. Uric acid levels were measured at 30, 60, and 90 minutes. The results showed that the pucuk merah ethanol extract 15 mg/KgBW (dose 2) had an anti-hyperuricemia activity of 62.42% compared to allopurinol 65.80%.
Tingkat Pengetahuan Dan Perilaku Swamedikasi Penggunaan Obat Bebas Pada Masyarakat Di Kecamatan Simpang Kanan Kabupaten Rokan Hilir Ayu Rahmawati; Nursyafni; Novtafia Endri; Muhammad Arif; Nawwar Irfan; Wulandari, Tri Ayu; Fitratul Wahyuni
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Self-medication is an act of self-medication carried out by the community to maintain health or manage disease based on personal diagnosis, using drugs repeatedly. This study aims to analyze the relationship between knowledge level and self-medication behavior using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency. The research was conducted observational with a cross-sectional approach, using quota sampling technique and questionnaires as instruments. The results showed that out of 90 respondents, 77.8% had good knowledge, 21.1% had sufficient knowledge, and 1.1% had poor knowledge. In terms of behavior, 81.1% had good behavior, while 18.9% had moderate behavior in self-medication. Analysis using the Chi-Square test resulted in a p-value of 0.002 (p<0.05), indicating a significant relationship between the level of knowledge and behavior of self-medication using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency.
Uji Aktivitas Antioksidan Ekstrak Etanol 70% Daun Pandan Wangi (Pandanus amaryllifolius Roxb) Dengan Metode DPPH Muhammad Arif; Ayu Rahmawati; Noveri Rahmawati; Nursyafni; Indah, Indah Kurniawati
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antioxidants and free radicals are topics that are increasingly discussed in the field of health and lifestyle. Free radicals, which result from oxidative stress, are known to play a role in the development of many serious diseases, such as cancer, cardiovascular disorders and premature aging. Antioxidants are able to neutralize free radicals, thus having the potential to prevent or reduce the impact of these diseases. This study aims to evaluate the antioxidant activity of ethanol extract of pandan wangi leaves (Pandanus amaryllifolius Roxb) using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method and determine the IC50 value as an indicator of effectiveness. Experimental methods were used to analyze antioxidant activity, with DPPH assays performed using a UV-Vis spectrophotometer. The results showed that the ethanol extract of pandan leaves had an IC50 value of 180.21 µg/mL, which was slightly lower than vitamin C as a positive control with an IC50 value of 136.03 µg/mL. Nevertheless, the antioxidant activity of pandan leaf extract is still in the moderate category, indicating its potential as a source of natural antioxidants. This study also emphasizes the importance of technical factors, such as temperature, incubation duration, and solvent quality, in influencing the test results. This study opens up opportunities for further development in the optimization of extraction and utilization of pandan wangi leaves as a natural ingredient to fight oxidative stress.
Co-Authors Abdul Azis Ade Rizki Nurmayadi Afifah Avilani Agus Supriatman Alpin Maulana Amiruddin Yahya Apriyana Triwulan Arvyndho Derra Aulia Fitri, Windy Binti Nuriyatul Muthi’ah Cepi Rahmat Hidayat Chandra Rizky Noviandi Dede Syahrul Anwar Devi Sri Agustin Dewi Gulyla Hari Dewi Nurhaliza Diana Santi Edi Suhardiana Efilia Meirita Elysa Eka Endang Lestari Ermira Nilansari Putri Esa Mahesa Evi Dewi Sri Mulyani Fauziah Tazkia Nur Fitratul Wahyuni Fitri Pujiyanti Fitria, Sarah Galih Pambayun Gya Tri Lestari I Made Suartika Ida Bagus Gede Manuaba Indah, Indah Kurniawati Jannah, Nurul Kamiel Roesman Bachtiar Lusi Indriani Maulida Nur Maya Rida Us Alifah Mestika, Diani Miftakhul Huda Muhammad Arif Muhammad Nur Zakia Mutiara Harkit Kamilatul Pu’adah N. Nurjanah Nabila Destiana Naufal Anasyi Nawwar Irfan Nevi Susianty Nggulam Zakia Nilama Wadnaty nisa, Annisa Nurul Maharani Nitya Nurul Fadilah Nofriyaldi, Ali Nola Fitri Noveri Rahmawati Novita Sari Novtafia Endri Nurbaiti Nurhasanah Nurjannah Nursyafni Nurul Fahida Oktavianus Sarno Prasiska Kholidya Prembayun Miji Lestari Rahmat Permana Reja Firman Saputra Rizky Nurul Melyani Rizky Subagya Rizva Alvina Rudi Hartono Shakynna Suandha Shinta Siti Sundari Siti Nabilah Hasna Sri Purnama Sari Srie Rezeki Nur Endah Sukarni Sunanih Teguh Ikhlas Ramadhan Teuku Mufizar Tsalitsatul Maulidah Ulfa Lailatul Vincent O. Imieje Wida Purwidianti Widhi Wicaksono Widya Nurul Aini Wilda Prasetya Winarti Wulandari, Tri Ayu YANTO Yulika Wati Zahra Aulia Nugraha