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All Journal Current Biochemistry JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Journal Of Nursing Practice Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Amerta Nutrition Jurnal Entomologi Indonesia Pekobis : Jurnal Pendidikan, Ekonomi, dan Bisnis SELL (Scope of English Language Teaching, Linguistics, and Literature) Journal Buletin Poltanesa International Archives of Medical Sciences and Public Health EKONOMIKA45 Jurnal Multidisiplin Madani (MUDIMA) Journal of Innovation Research and Knowledge Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Innovation, Theory & Practice Management Journal Perigel: Jurnal Penyuluhan Masyarakat Indonesia Kanigara Jurnal Pengabdian Masyarakat Jurnal Lentera Kesehatan Masyarakat (JLKM) Advances in Environmental Innovation (ANEVA) Jurnal Penelitian Hasil Hutan Journal of Social And Education Research Professional Evidence-based Research and Advances in Wellness and Treatment
Sulistiyani
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Combination of Pulai Leaf (Alstonia scholaris (L.) R. Br.) and Papaya Leaf (Carica papaya L.) Water Extract as HMG-CoA Reductase Inhibitor Sulistiyani; Andrianto, Dimas; Mariati, Sri
Current Biochemistry Vol. 11 No. 1 (2024)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.11.1.3

Abstract

Heart disease has become the leading cause of death in the world in the last 15 years. This disease has several primary risk factors, one of which is hypercholesterolemia. Cholesterol biosynthesis in the liver is influenced by the activity of the rate-limiting enzyme, HMG-CoA reductase. Traditional herbal medicine provides alternative treatment for hypercholesterolemia. Both pulai and papaya leaves were reported as HMG-CoA reductase inhibitors. There has been very limited study however, on the efficacy of a mixture of aqueous extracts of the two in inhibiting HMG-CoA reductase. This study aims to determine the activity of a mixture of water extracts of both pulai and papaya leaves. The activity of the enzyme HMG-CoA reductase was measured by Abcam® kit No. Ab204701 by spectrophotometric method at 334 nm. The results showed that the three extracts of the combination of pulai and papaya leaves had four times better inhibitory action than the single extract (p0.05). The results of the phytochemical literature study showed that the aqueous extract contained flavonoids, alkaloids, tannins, and saponins
Kandungan Nutrisi dan Daya Inhibisi α-glukosidase Ekstrak Daging Buah Salak Sidempuan (Salacca sumatrana) Safithri, Mega; Ritonga, Aprilita Putri Defan; Indariani, Susi; Dwicesaria, Maheswari Alfira; Sulistiyani; Hasim
Current Biochemistry Vol. 11 No. 1 (2024)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.11.1.1

Abstract

Penelitian terhadap pemanfaatan salak khususnya salak Sidempuan sebagai inhibitor α-glukosidase belum dilakukan. Penelitian ini bertujuan mengukur kadar proksimat (air, abu, protein kasar, lemak kasar, serat kasar, dan karbohidrat), menganalisis komponen fitokimia, kandungan total fenolik dan aktivitas penghambatan α-glukosidase pada ekstrak air dan etanol daging buah salak Sidempuan. Kadar total fenol diukur menggunakan metode Folin Ciocalteu. Aktivitas penghambatan α-glukosidase diukur menggunakan substrat pNPG. Kadar karbohidrat, air, abu, lemak kasar, protein kasar, dan serat kasar berturut-turut sebesar 86.35%, 6.57%, 3.60%, 1.44%, 1.24%, dan 0.82%. Kedua ekstrak mengandung senyawa flavonoid dan saponin. Ekstrak etanol 70% daging buah salak Sidempuan memiliki kandungan total fenol sebesar 10.6 mg GAE/g ekstrak, lebih tinggi dibandingkan ekstrak air sebesar 5.55 mg GAE/g esktrak. Ekstrak etanol daging buah salak Sidempuan memiliki konsentrasi inhibisi (IC50) sebesar 13.69 mg/L. Konsentrasi ini lebih kecil dibandingkan ekstrak air yaitu 4160.56 mg/L, namun masih lebih besar dibandingkan akarbosa yaitu 1.15x10-3 mg/L sebagai kontrol positif.
The Relationship Between Parental Support on Children Oral Health and Children Dental Caries in Agroindustrial Area of Jember Kiswaluyo; Roedy Budirahardjo; Sulistiyani; Elyda Akhya Afida Misrohmasari; Ni Luh Putu Maharani Eka Putri
Jurnal Multidisiplin Madani Vol. 3 No. 9 (2023): September, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/mudima.v3i9.5249

Abstract

Dental caries is a multifactorial disease that children experience. Parents' behavior to support children is essential in maintaining children's oral health. The social environment, such as the farming community in the agricultural environment, shapes people's behavior.   This study aimed to analyze the relationship between parental support on children's oral health and dental caries in the agroindustrial area of Jember. This study is an analytical observational design with cross-sectional approach. This study was held in SDN Candijati 01 and SDN Biting 04, Arjasa Jember, and attended by 36 pairs of parents and students in 5th  grade. Children were examined for the presence of dental caries based on Class 1 caries of Black Classification. A set of questionnaires was given to the parents to assess parental support on oral health. Chi-Square test was performed to find the relationship between dental caries and parental support. The study results showed that Class 1 Caries was present in 100% of children who lacked parental support on oral health. There is a significant relationship between dental caries and parental support on children's oral health in children of the agroindustrial area of Jember
Daya Tarik Produk UMKM sebagai Tolak Ukur Kepuasan Konsumen Sulistiyani; Pratama, Aditya
Poltanesa Vol 23 No 1 (2022): Juni 2022
Publisher : P3KM Politeknik Pertanian Negeri Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51967/tanesa.v23i1.1050

Abstract

UMKM (Usaha Mikro Kecil dan Menengah) sebagai motor penggerak roda perekonomian di kalangan masyarakat. UMKM mampu mengurangi tingkat pengangguran. Keberhasilan UMKM dapat dilihat dari tingkat kepuasan konsumen terhadap barang yang telah dikonsumsi. Kepuasan konsumen menjadi tujuan utama dari pelaku UMKM. Konsumen yang merasa puas saat menggunakan produk atau jasa berkaitan dengan keberlangsungan suatu usaha. Untuk mengidentifikasi faktor apa saya yang memiliki hubungan dengan kepuasan konsumen. Variabel bebas yang hendak digunakan yaitu Kualitas produk yang dihasilkan, kualitas pelayanan yang dilakukan dan harga yang sudah ditetapkan. Sebanyak 48 orang survei secara langsung untuk mendapatkan data yang digunakan untuk analisis di dalam penelitian. Data diperoleh akan melalui tahapan pertama yaitu uji validitas dan uji reliabilitas. Dalam penelitian ini setelah kuesioner dinyatakan valid dan reliabel sebanyak 66 pernyataan. Tahapan selanjutnya penggunaan teknik analisis regresi linier berganda. Penggunaan regresi linier berganda telah memenuhi persyaratan yang sudah ditetapkan berupa lolos pada uji prasyarat analisis berupa uji normalitas, uji multikolinearitas, uji heteroskedastisitas, uji autokorelasi. Setelah melakukan olah data menggunakan bantuan software SPSS diperoleh yaitu tidak ada kontribusi yang diberikan kualitas produk pada saat pengukuran kepuasan konsumen yang telah menggunakan produk barang. Masing-masing variabel kualitas pelayanan, harga mampu memberikan pengaruh pada kepuasan konsumen. Adapun secara simultan keseluruhan variabel independen dapat memberikan pengaruh maupun kontribusi dengan kepuasan konsumen setelah menggunakan suatu produk.
Potensi ekstrak maggot lalat tentara hitam Hermetia illucens (Linnaeus) dalam regulasi mekanisme antioksidan selular dan antiradang: Kajian in silico: The potential of black soldier fly Hermetia illucens (Linnaeus) maggot extracts in the regulation of cellular antioxidant and anti-inflammatory mechanisms: In silico study Sulistiyani; Firdaus, Muhamad Fajar; Sigiro, Ria Heni; Nawangsih, Abdjad Asih; Purwanto, Ukhradiya Magharaniq Safira; Andrianto, Dimas
Jurnal Entomologi Indonesia Vol 20 No 3 (2023): November
Publisher : Perhimpunan Entomologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5994/jei.20.3.223

Abstract

The potential of black soldier fly (Hermetia illucens (Linnaeus), BSF) maggots as the source of biopharmaca, has not been extensively studied. This research aimed to identify bioactive compunds in BSF maggot extract that potentially activate antioxidant signaling mechanism. BSF maggots fed with vegetable waste were extracted based on maceration method with water, methanol, and acetone as solvents. Forty bioactive compounds were identified by liquid chromatography-mass spectrometry: 15 were in the aqueous extract, 13 were from methanolic extract, and 12 were in the acetone extract. Most of those compounds (90%) were having high bioavailability score (= 0.55 or more) and relatively low toxicity (500 mg/Kg<LD50<5000mg/Kg BW). Molecular docking predicted that there were 26 bioactive compounds potential to activate cellular antioxidant signaling through activation of NRF2 transcription factor, better than the commercial NRF2 activator. The aqueous extract compound with PubChem CID: 73775828 was the best one that inhibited NRF2 signaling by binding to Keap-1 protein (PDB ID: 6FFM) with Gibbs free energy (ΔG) = -6.08 Kcal/mol and dissociation constant (Kd) = 3.58 í— 10-5 µM. Whereas inhibition of inflammation via NF-kappa B signaling was shown by an aqueous extract compound verpacamide A which bound inhibitor NF-kappa B kinase (IKK2) (PDB ID: 4KIK) with ΔG = -5.024 kcal/mol; Kd = 0.207 í— 103 µM. This potency was better than that of aspirin. In conclusion, BSF maggot extracts are source of biopharmaca with potential cellular antioxidant and anti-inflammatory activity.
FENOL, FLAVONOID, DAN AKTIVITAS ANTIOKSIDAN PADA EKSTRAK KULIT BATANG PULAI (Alstonia scholaris R.Br) Zuraida; Sulistiyani; Dondin Sajuthi; Irma Herawati Suparto
Jurnal Penelitian Hasil Hutan Vol. 35 No. 3 (2017): Jurnal Penelitian Hasil Hutan
Publisher : BRIN Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/jphh.2017.35.3.211-219

Abstract

Alstonia scholaris R.Br belongs to family Apocynaceae, is one of medicinal forest plant as traditional medicine to treat fever, malaria, cough with phlegm, diarrhea, diabetes, cholesterol-lowering, intestinal worms, acute rheumatism, ulcers, and hypertension. One of the causes of heart disease, atherosclerosis, and cancer is oxidative stress. The stress can be cured or reduced by taking antioxidant. Flavonoid, a phenol compound class, is one of the secondary plant metabolites that function as antioxidant. This paper determines total levels of phenol, flavonoid, and antioxidant activity of Alstonia *stem bark extract (Alstonia scholaris R. Br). Quantitative determination of total phenolics with the folin-ciocalteu method expressed as mg of gallic acid equivalent (GAE) per gram of extract, total flavonoids content by AlCl₃ method expressed as Quercetin equivalent (QE), and in vitro antioxidant activities with DPPH (2,2-diphenyl-1-picrylhydrazyl) method expressed in terms of IC₅₀ (inhibition concentration). Results show that extraction of three replicates in maceration with 96% ethanol yielded 4.19% filtrate. The total phenolic content was 51.50 mg GAE /g extract, while the total flavonoid content was 0.35 mg QE /g extract. IC₅₀ value of antioxidant activity assay of stem bark extract was 211.54 µg/mL.
PEMANFAATAN INOVASI PRODUK LOKAL UBI UNGU PADA KELURAHAN MANGUNSARI KECAMATAN GUNUNGPATI, KOTA SEMARANG Sulistiyani; Gita Sugiarti; Aris Mardiyono
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 11 (2025): BESIRU : Jurnal Pengabdian Masyarakat, November 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i11.1968

Abstract

Program pengabdian kepada masyarakat ini bertujuan mengoptimalkan potensi ubi ungu sebagai produk lokal unggulan di Kelurahan Mangunsari, Kecamatan Gunungpati, Kota Semarang, melalui pengembangan inovasi olahan pangan dan penguatan kapasitas usaha masyarakat. Selama ini, ubi ungu telah dibudidayakan oleh masyarakat, namun pemanfaatannya masih terbatas sebagai konsumsi rumah tangga dengan nilai tambah ekonomi yang rendah. Keterbatasan pengetahuan pengolahan, manajemen usaha, dan strategi pemasaran menyebabkan produk ubi ungu belum berkembang sebagai sumber pendapatan yang berkelanjutan. Kegiatan pengabdian dilaksanakan melalui beberapa tahapan: (1) pemetaan potensi dan kebutuhan masyarakat; (2) pelatihan inovasi produk olahan ubi ungu (brownies, cookies, stik, keripik, dan minuman fungsional); (3) pelatihan manajemen usaha sederhana (pencatatan keuangan, perhitungan harga pokok produksi, dan analisis laba rugi); (4) pelatihan pemasaran, termasuk pengemasan, branding, dan pemasaran digital sederhana; serta (5) pendampingan dan monitoring implementasi usaha. Hasil kegiatan menunjukkan peningkatan pengetahuan dan keterampilan peserta dalam mengolah ubi ungu menjadi produk bernilai jual, serta terbentuk beberapa kelompok usaha kecil yang mulai memproduksi dan memasarkan produk secara rutin di lingkungan kelurahan, acara lokal, dan melalui media sosial. Program ini berdampak pada penguatan kemandirian ekonomi, peningkatan rasa percaya diri, dan tumbuhnya jiwa kewirausahaan di kalangan ibu rumah tangga dan pemuda. Tantangan utama yang dihadapi antara lain keterbatasan modal, kontinuitas pasokan bahan baku, konsistensi kualitas produk, penguasaan teknologi informasi, dan legalitas produk. Melalui pendampingan berkala, pembentukan kelompok usaha, dan jejaring dengan pemerintah kelurahan serta mitra eksternal, beberapa tantangan tersebut mulai dapat diatasi secara bertahap.
The Objective of this Study is to Examine the Relationship Between Nurses' Knowledge Levels of Patient Safety Identification and the Implementation of These Practices in Hospitals Lamria Situmeang; Sumarmi; Sulistiyani; Samsir
Professional Evidence-based Research and Advances in Wellness and Treatment Vol. 1 No. 3 (2024): September, 2024
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/perawat.v1i2.51

Abstract

Patient safety is one of the main components in improving the quality of health services (Permatha Indah et al., 2022). Patient safety includes a series of actions aimed at preventing injury or unwanted complications during the care process (Sari, 2020; Sitepu, 2020; (Oktiana Tamba, 2020). This study aims to explore the relationship between nurses' level of knowledge about identification in patient safety and the implementation of these procedures in the inpatient room. This study used a descriptive correlational design with a quantitative approach. This design was chosen to determine the relationship between nurses' level of knowledge about identification in patient safety and the implementation of this identification in the inpatient room. Most respondents have a fairly good level of knowledge as many as 50 people (78.1%), while only 14 people (21.9%) have good knowledge. based on the implementation of identification in patient safety is quite good as many as 51 people (79.7%), while only 13 people (20.3%) carry out well. The p-value of 0.0001 indicates a significant relationship between the level of knowledge of nurses about identification in patient safety with the implementation of identification in patient safety. Understand the importance of effective education and training to improve knowledge and implementation of identification, which ultimately aims to improve patient safety.
Analisis Profil Metabolit Sekunder Ekstrak Etanol Brokoli (Brassica oleracea var. italica) pada Pemupukan Biokonversi Maggot Black Soldier Fly Purwanto, Ukhradiya Magharaniq Safira; Sulistiyani; Azizah, Anisa Nur Wahida; Rosyidah, Rara Annisaur
Current Biochemistry Vol. 12 No. 2 (2025)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.12.2.3

Abstract

Brokoli (Brassica oleracea var. italica) merupakan sayuran fungsional yang diketahui mengandung berbagai senyawa bioaktif dengan potensi nutrisi dan farmakologis yang penting. Penelitian ini bertujuan untuk memprofilkan senyawa bioaktif ekstrak brokoli yang dibudidayakan dengan perlakuan pemupukan berbeda, yaitu kontrol, pupuk kandang, dan pupuk biokonversi maggot black soldier fly (BSF). Sampel brokoli diekstraksi menggunakan etanol 80%, kemudian dianalisis dengan LC-MS/MS untuk mengidentifikasi dan mengkuantifikasi komposisi metabolit. Hasil penelitian menunjukkan bahwa perlakuan pupuk biokonversi maggot menghasilkan pertumbuhan tanaman yang lebih baik, meliputi tinggi tanaman, jumlah daun, biomassa segar dan kering, serta persentase berbunga dibanding perlakuan lain. Selain itu, perlakuan ini juga menghasilkan metabolit yang lebih beragam dengan kelimpahan lebih tinggi, terutama golongan fenolik, terpenoid, piridazin, dan indol. Beberapa senyawa utama yang teridentifikasi antara lain Indole-3-Propionic Acid dan N(1),N(8)-Bis(Coumaroyl)Spermidine(1+), serta turunan klorofil seperti pyropheophorbide-a yang ditemukan dengan kelimpahan signifikan. Temuan ini menunjukkan bahwa pupuk biokonversi maggot BSF mampu meningkatkan pertumbuhan sekaligus profil metabolit sekunder brokoli, sehingga berpotensi sebagai strategi pemupukan ramah lingkungan untuk meningkatkan kualitas nutrisi dan fungsional tanaman ini. 
Cross-Sectional Analysis of Rayon Fiber Exposure and Lung Function Among Weavers in Pemalang, Indonesia Sulistiyani; Mursid Raharjo; Nikie Astorina Yunita Dewanti; Retno Murwani; Muhammad Auliya Rahman
JURNAL KESEHATAN LINGKUNGAN Vol. 18 No. 1 (2026): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v18i1.2026.26-35

Abstract

Introduction: Sarung Goyor is one of the popular textile industries in Indonesia. The manual production process results in the release of a high number of dust particles into the air, including rayon fibers, which are a major component of the fabric. Inhaling fine fibers causes respiratory tract irritation and impaired lung function. There hasn't been much research exploring rayon dust exposure related to small-scale weaving crafts. This study aims to find a relationship between rayon fibers and lung function among sarong weavers in Indonesia. Methods: A cross-sectional study was carried out at the Sarung Goyor Industry Center North Wanarejan, Pemalang, involving 101 male weavers. The data collected includes total dust and inhalable dust levels, lung function values, and ventilation area.Dust sampling was performed using the Hi-Q HVP-2000 and SKC PCXR 8000, and lung function values were measured using the Spiro LAB III according to ATS standards. Data were analyzed using the Kolmogorov-Smirnov test and correlation test. Results and Discussion: 78% of respondents experienced impaired lung function, obstructive 22%, restrictive 46.5%, and mixed 18.8%. There is a strong relationship between age and restriction (p = 0.001) as well as inhaled dust and restriction (p = 0.026). A statistically significant inverse association was identified between ventilation area and the presence of obstructions. Conclusion: Rayon has a significant impact on lung function, causing restriction and obstruction over time. Therefore, it is essential to advocate for improved workplace ventilation and the consistent use of protective masks among weavers.
Co-Authors Abdjad Asih Nawangsih Abdul Azis Akbar Aditya Pratama agustin, anggi_14 Amsar Ari Tri Wanodyo Handayani Arini Hidayah, Arini Aris Mardiono Aris Mardiyono Azizah, Anisa Nur Wahida Caecilia Sri Haryanti Camilius Denok Julianingsih Dian Purnamasari DIMAS ANDRIANTO Dondin Sajuthi Dwicesaria, Maheswari Alfira Efendi, Tri Achmad Elyda Akhya Afida Misrohmasari Endang Khoirunnisa Firdaus, Muhamad Fajar Fitriani, Janiyah Intan Gita Sugiarti Hasim Hikmah Indah, Dewi Rosaria Indariani, Susi Indrayanti Irma Herawati Suparto Kamaratih Aprilia Kiswaluyo Lalu Guntur Payasan Lamria Situmeang Mega Safithri Mei Rianita Elfrida Sinaga Mei Rianita Sinaga Misrohmasari, Elyda Muchayatin Muhammad Auliya Rahman Mursid Raharjo Nainggolan, Santy Ercelina Ni Luh Putu Maharani Eka Putri Nikie Astorina Yunita Dewanti Ninef, Violin Irene Novitasari, Ade Nur Rahman, Arif Nurhidayah, Sri Ontran Sumantri Riyanto Pamase, Ulrico Adnan Parera, Magdalena Junu Payasan, Lalu Guntur Prihantini, Apsari Fajar Purwanto, Ukhradiya Magharaniq Safira Putri, Nur Aini Saura Rachmawati, Septi Nur Rahayu, Endah Sri Retno Heru Setyorini Retno Murwani Ritonga, Aprilita Putri Defan Roedy Budirahardjo Rosaria Indah, Dewi Rosyidah, Rara Annisaur Samsir Sigiro, Ria Heni Silwana, Amalia Soenarmi, Fransisca R. Sri Mariati Subaidah Sumarmi Suparjo Surartono Dwiatmoko Widayanti, Evi Yuniarto, Galuh Zuraida