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All Journal MEDIA PETERNAKAN - Journal of Animal Science and Technology ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Buletin Peternakan Jurnal Veteriner BIOTROPIA - The Southeast Asian Journal of Tropical Biology Jurnal Ilmu Ternak Veteriner Tadarus: Jurnal Pendidikan Islam Tropical Animal Science Journal ARSHI Veterinary Letters Jurnal Ilmiah Mandala Education (JIME) Jurnal Buana Farma Livestock and Animal Research Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis
Amrozi
Bogor Agricultural University
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Energy Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences Veterinary Other

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Journal : Tropical Animal Science Journal

 1 
Quantitative Histomorphometry of Pre-ovulatory Follicles and Uterine Glands of Ongole-grade Heifer in Response to the Low Doses of PMSG Administration K. B. Putro; A. Winarto; Amrozi; A. Boediono; W. Manalu
Tropical Animal Science Journal Vol. 46 No. 1 (2023): Tropical Animal Science Journal
Publisher : Faculty of Animal Science, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5398/tasj.2023.46.1.1

Abstract

Injection of female mammalian animals with gonadotropin prior to mating using superovulation dose increases estradiol 17beta (E2) synthesis and secretion and improves the growth and development of the uterus to support prenatal growth with the side effect of increasing litter size. This experiment was designed to study the effects of low doses of PMSG injection in heifers on the growth of granulose cells (GC) of pre-ovulatory follicles, E2 synthesis, and uterine glands growth and development. Nine Ongole-grade heifers were divided into three groups of doses of PMSG injection, i.e., 0 IU/kg BW, 0.5 IU/kg BW, and 1.0 IU/kg BW. The injection of pregnant mare serum gonadotropin (PMSG) was conducted at the early stage of the second follicle wave. Blood samples were collected at estrus (day 0) to measure plasma E2 concentrations. The ovary and uterus were collected for histological observation after slaughtering the animal. The results showed that non-superovulation doses of PMSG injections at the second follicle wave significantly increased the growth of GC that eventually produced a significantly higher plasma E2 concentration by 39.47% and 113.57%, in heifers receiving 0.5 IU/kg BW and 1.0 IU/kg BW (p<0.05), respectively. The increase in E2 synthesis and secretion significantly stimulated the growth and development of uterine glands (p<0.05), which was reflected in the improved measures of uterine glands. In conclusion, injections of heifers with low doses of PMSG at the second follicle wave could increase the growth of GC to produce a higher secretion of E2 that eventually improves the growth and development of uterine glands in the endometrium without the risk of multiple calving.
In Vitro, In Compost, and In Vivo Assessment of Chitosan-Polyethylene Glycol as an Intravaginal Insert for Progesterone Delivery in Sheep E. Y. Yessa; L. I. T. A. Tumbelaka; I. Wientarsih; M. F. Ulum; B. Purwantara; Amrozi
Tropical Animal Science Journal Vol. 46 No. 3 (2023): Tropical Animal Science Journal
Publisher : Faculty of Animal Science, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5398/tasj.2023.46.3.295

Abstract

In estrous synchronization, the hormone progesterone is an important element. Various hormone preparations currently available have limitations, especially those related to environmental impact issues. Various alternatives are being studied, and using biodegradable polymeric materials (chitosan-polyethylene glycol combination) to develop new devices is considered one of the solutions. This contribution aims to design and evaluate intravaginal implants that can release progesterone and be degraded in the body and the environment. Implants are made by melting and molding techniques. In vitro drug release studies using dyes as drug models. Implant degradation studies tested in compost. Changes in the shape of the implant, while it is in the vagina, are observed by ultrasound. Blood collection was performed three days before and during implantation to obtain a blood progesterone profile. In vitro drug release studies using dye as a drug model showed a chitosan-PEG profile that released the drug faster at first, then slowed down. Implant degradation studies in compost and vagina demonstrated a gradual degradation process. The blood progesterone profile increased during implantation, as high as 15 ng/mL on the third day. In conclusion, the chitosan-PEG intravaginal implant formulation designed using the melting and molding technique proved to be degraded in the compost environment. It released the hormone progesterone for four days according to the degradation period of the implant in the vagina.
Co-Authors . Aryogi A. Boediono A. Winarto Ade Ocktaviani Ade Ocktaviani, Ade Adi Winarto Afiqah binti Abd Latif Agik Suprayogi Agus Setiyono Akbar Wijaya Putra Purnama Andriani Andriani Andriyanto . Andriyanto A Andriyanto Andriyanto Anita Esfandiari Arief Boediono Arifianto, Dinar Arman Sayuti Arman Sayuti Asrori Asrori Aulia Andi Mustika Azery bin Kamiring B Purwantara B Purwantara B. Purwantara Bagus Setiawan Bagus Setiawan Bambang Purwantara Bambang Purwatara Bambang Purwatara, Bambang Bambang Sigit Widodo Bayu Febram Prasetyo Bondan Achmadi Bondan Achmadi Bondan Achmadi Bondan Achmadi, Bondan Budianto Panjaitan D Sajuthi Darsono Darsono Dedi Rahmat Setiadi Diah Nugrahani Pristihadi Dian Masyitha E. Y. Yessa Edelina Sinaga Elma Yuliani Yessa Erly R Adistya Erly Rizka Adistya Erly Rizka Adistya Fiqhi Alfiansyah Hamdika Yendri Hazar Sukareksi Hazar Sukareksi, Hazar Herdis . Herdis H Herdis H Herdis Herdis Hidayati Mukarromah Hidayati Mukarromah Ho Kin Wai I Supriatna I wayan Teguh Wibawan I. Wientarsih Ietje Wientarsih IETJE WIENTARSIH Iga Mahardi Iga Mahardi Iman Supriatna Juli Melia Juli Melia K. B. Putro Kamiliyah, Kamiliyah Kiki Amalia Rama koekoeh santoso Krido Brahmo Putro Kudang Boro Seminar Langgeng Priyanto Leo Sapelani Soinbala Ligaya I. T. A. Tumbelaka Ligaya ITA Tumbelaka Luci Parwati M Agus Setiadi M Ibnu Satria M. F. Ulum M. Ibnu Satria Maharani Maharani, Maharani Mokhamad Fakhrul Ulum, Mokhamad Muchidin Noordin MUHAMMAD AGIL Muhammad Danang Eko Yulianto Muhammad Imron Muhammad Imron Muhammad Imron Mutmainnah Mutmainnah Mutmainnah Mutmainnah Ni Wayan Kurniani Karja nisfu bayu kurniadi Nugroho Sampurno Nur Anisa BS Nurul Taufiqu Rochman Nurul Taufiqu Rochman Oriza Savitri Ariantie Oriza Savitri Ariantie P Situmorang Parwati, Luci R I Afiriantini Rachmat Herman Rahminiwati, Min Rastina Rastina Riasari Gail Sianturi Ridi Arif Rivangga Yuda Hendika Roslizawaty r Roslizawaty r Roslizawaty Roslizawaty Rusdin - Santoso . Santoso S Santoso S Santoso Santoso Sari Yanti Hayanti Satya Gunawan Setiadi, Hirawan Siti Dwi Rahmah Ayumi Solly Aryza Srihadi Agungpriyono Sriyanto - Sugganya a/p Ravi Syafruddin S Syafruddin s T L Yusuf Tukiran TUTY LASWARDI YUSUF Tuty Laswardi Yusuf Tuty Laswardi Yusuf W. Manalu Wasmen Manalu Yessa, Elma Yuliani Yudha Fahrimal Yudha Fahrimal Yudi Eka Satria