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Fluor Albus Characteristics Associated with Sexually Transmitted Infection (STI) in Makassar Pregnant Women Haruna, Nadyah; Hatta, Mochammad; Hamid, Firdaus; Madjid, Baedah; Patellongi, Ilhamjaya; Farid, Monika Fitria
Al-Sihah : The Public Health Science Journal Volume 15, Nomor 2, July-December 2023
Publisher : Program Studi Kesehatan Masyarakat UIN Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-sihah.v15i2.38797

Sexually Transmitted Infection (STI) is a common condition with increased prevalence among pregnant women and can negatively affect the fetus. According to WHO, a total of 374 million new cases of STI are projected to occur in 2020, including gonorrhea (82 million), syphilis (7.1 million), and trichomoniasis (156 million). Therefore, this study aimed to determine the relationship between the characteristics of vaginal discharge (fluor albus) in pregnant women and STI. The descriptive method was used with a cross-sectional design, and the procedures were conducted in May 2023. The sample population comprised all pregnant women with ANC in Makassar during the study period. Vaginal swabs were obtained from 127 pregnant women who were willing to participate and had vaginal discharge. The results showed that 53 participants reported having physiological flour albus, while 74 had pathological symptoms. Itching and odor were reported to be the most common clinical signs associated with patients' abnormal vaginal discharge, followed by itching, pain, and odor. Furthermore, a significantly high prevalence of the condition was observed among pregnant women aged 20-30 years. Based on the results, the predominant symptom of fluor albus was itching and odor when combined with microorganisms that caused STI. Several pregnant women with clinical complaints also had microorganisms apart from those associated with STI. These results indicated the pressing need to develop additional testing in pregnant women with fluor albus, particularly those with concomitant symptoms.

Profile of Clinical, Radiological and Laboratory Pattern in TB-HIV Coinfection in National Infection Centre of Indonesia Rosamarlina, Rosamarlina; Hatta, Mochammad; Murtiani, Farida; Widiantari, Aninda Dinar
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 2 (2024): September 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i2.3959

Background: The study aims to map TB (Tuberculosis) – HIV (Human Immunodeficiency Virus) patients based on clinical, radiological, and laboratory patterns. Objective: This study is expected to provide previous research investigating radiologic and laboratory examinations in TB-HIV patients. Method: We conducted a cross-sectional study based on medical records of TB-HIV patients at RSPI Sulianti Saroso from January 2004 - March 2017. Samples were 240 TB-HIV patients from a population of 1014 People Living with HIV/AIDS (PLWHA). Inclusion criteria were PLWHA, aged over 18 years, diagnosed with TB with completed medical record status. Result: Characteristics of the majority of patients were in the productive age group (99.2%) with an average age of 33 years and male sex (78%). The main symptom is cough (91.7%) and cough with phlegm (59.1%). Most patients (83.37%) have not received ART (Anti-Retroviral Therapy). Pulmonary physical examination showed that most patients had Ronchi (95.8%) while others got wheezing (5%). Laboratory tests revealed an initial CD4 cell count of 71.6 cells/ml and a negative Acid-Fast Bacillus (AFB) smear (59.2%). The patient's radiology was mainly with an infiltrate (82.5%); most infiltrate was presented in apex (52.4%). Conclusion: The majority of TB-HIV coinfected patients are young males, presenting with common TB symptoms, low CD4 counts, and negative AFB smears, complicating diagnosis. Radiological findings frequently show infiltrates, particularly in the apex. These findings emphasize the importance of early diagnosis and ART initiation to improve outcomes in TB-HIV coinfected patients

DETEKSI BAKTERI ATIPIKAL DARI SWAB NASOFARING PENDERITA SEPSIS NEONATORUM DI RS WAHIDIN SUDIROHUSODO MENGGUNAKAN POLYMERASE CHAIN REACTION (PCR) MULTIPLEKS Fadhilah; Sjahril, Rizalinda; Hatta, Mochammad; Bahagia, Dwi; Alasiry, Ema; Tarini, Ni Made Adi
Majalah Kesehatan Vol. 11 No. 4 (2024): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/majalahkesehatan.2024.011.04.1

Sepsis neonatorum merupakan penyebab signifikan kematian neonatorum dan morbiditas jangka panjang. Infeksi bakteri atipikal berperan penting dalam sepsis neonatorum, namun sulit dideteksi dengan teknik mikrobiologi konvensional. Penelitian ini bertujuan untuk mendeteksi bakteri atipikal yaitu Chlamydia trachomatis, Mycoplasma pneumonia, Legionella pneumophila dan Ureaplasma urealyticum dengan Polymerase Chain Reaction (PCR) multipleks dari swab nasofaring pasien sepsis neonatorum yang dirawat di RS Wahidin Sudirohusodo Makassar. Penelitian ini merupakan penelitian observasional deskriptif pada neonatus dengan dugaan sepsis. Neonatus yang diduga sepsis akan diambil swab nasofaring kemudian diperiksa untuk mendeteksi Chlamydia trachomatis, Mycoplasma pneumonia, Legionella pneumophila dan Ureaplasma urealyticum menggunakan PCR multipleks. Pemeriksaan pasien sepsis neonatorum yang dirawat di NICU RS Wahidin Sudirohusodo Makassar menggunakan sampel swab nasofaring pada bulan September 2022 hingga Juni 2023 menunjukkan bahwa dari 60 pasien yang diperiksa swab nasofaring, 8 (13,33%) pasien terdeteksi infeksi tunggal bakteri atipikal yaitu Mycoplasma pneumonia, Chlamydia trachomatis dan Legionella pneumophila serta 12 pasien (20%) di antaranya adalah infeksi multipel yaitu Mycoplasma pneumoniae dan Chlamydia trachomatis; Legionella pneumophila dan Chlamydia trachomatis; Mycoplasma pneumoniae, Chlamydia trachomatis dan Legionella pneumophila. PCR merupakan modalitas yang menjanjikan untuk mendeteksi bakteri atipikal dari swab nasofaring pasien sepsis neonatorum yang sulit diidentifikasi dengan teknik konvensional. Hal ini sangat berguna untuk memberikan terapi yang cepat dan tepat pada pasien sepsis neonatorum.

EFFECT OF INTERACTIVE PREGNANCY EDUCATION (IPE) ON STRESS LEVELS AMONG PRIMIGRAVID TRIMESTER III PREGNANT WOMEN Elli Hidayati; Syahrul Rauf; Mochammad Hatta; Sonny T. Lisal; Fatimah; Hamidah
Muhammadiyah International Public Health and Medicine Proceeding Vol. 4 No. 1 (2024): PROCEEDING MUHAMMADIYAH INTERNATIONAL PUBLIC HEALTH AND MEDICINE CONFERENCE - F
Publisher : Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61811/miphmp.v4i1.658

The Infant Mortality Rate (IMR) is an indicator in determining the health level of a country. Infant mortality is caused by various health problems, especially since the gestation period, even starting before the gestation period. Stress during pregnancy affects the motor, cognitive and emotional development of the baby. This study aims to determine the effect of Interactive Pregnancy Education (IPE) on levels in third trimester primigravida pregnant women. This research is a quasi-experimental study using a nonequivalent control group design. This research was conducted in the Kemayoran and Cempaka Putih Community Health Centers in DKI Jakarta from December 2021 to completion. The samples were 30 third trimester primigravida pregnant women for the intervention and control groups. Data were analyzed using the Mann Whitney and Wilcoxon tests with SPSS 22 software. The results showed that there was a significant difference between the median stress scores in the control group before and after the median decreased after the intervention and the difference in the median stress scores before and after the intervention in the intervention group was greater than the control group, which decreased to 6.50. This shows that IPE is effective in reducing stress in pregnant women who have previously had stress with high stress scores.

Prevalence human papillomavirus type 6 and type 11 in pregnant women Haruna, Nadyah; Hatta, Mochammad; Hamid, Firdaus; Sultan, Andi Rofian; Safri, Safri; Farid, Monika Fitria; Lestari, Esa
MEDISAINS Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23103

Background: Pregnancy reduces the effectiveness of cell-mediated immunity, making the body more vulnerable to Human Papilloma Virus (HPV) infection. HPV comes in multiple variants, including non-pro-oncogenic varieties like 6 and 11. Less research has been done on low-risk HPV infections than on high-risk HPV since they are more frequently linked to genital warts and rarely result in cancer. Examples of these infections are types 6 and 11. It is necessary to conduct this study to ascertain whether asymptomatic pregnant women have been exposed to HPV types 6 and 11.Purpose: This study aims to determine prevalence HPV types 6 and 11 in pregnant women.Methods: A descriptive cross-sectional survey was carried out in Makassar in May 2023. The study Population consisted of pregnant women who underwent antenatal care at Tajuddin Chalid Hospital Makassar during the specified research period. After providing clarification and obtaining consent from eligible mothers, we collected a swab from the vaginal area. A PCR examination was conducted on the 167 maternal swabs that were received. Statistical analyses included frequency distribution using SPSS.Results: According to the study, 121 (72.5%) of the 167 samples tested positive for HPV type 6 DNA, while 46 (27.5%) tested negative. Meanwhile, 67% of 167 patients tested positive for HPV type 11 but were negative for the virus. Only 21 respondents with negative identification were found to be harboring both low-risk Human Papillomavirus types. In addition, 78 respondents received positive results for HPV types 6 and 11.Conclusion: Pregnant women can be infected with HPV types 6 and 11 even if they are asymptomatic. The high percentage of positive results suggests that routine maternal screening is recommended, especially during pregnancy.

Prevalence human papillomavirus type 6 and type 11 in pregnant women Haruna, Nadyah; Hatta, Mochammad; Hamid, Firdaus; Sultan, Andi Rofian; Safri, Safri; Farid, Monika Fitria; Lestari, Esa
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23103

Background: Pregnancy reduces the effectiveness of cell-mediated immunity, making the body more vulnerable to Human Papilloma Virus (HPV) infection. HPV comes in multiple variants, including non-pro-oncogenic varieties like 6 and 11. Less research has been done on low-risk HPV infections than on high-risk HPV since they are more frequently linked to genital warts and rarely result in cancer. Examples of these infections are types 6 and 11. It is necessary to conduct this study to ascertain whether asymptomatic pregnant women have been exposed to HPV types 6 and 11.Purpose: This study aims to determine prevalence HPV types 6 and 11 in pregnant women.Methods: A descriptive cross-sectional survey was carried out in Makassar in May 2023. The study Population consisted of pregnant women who underwent antenatal care at Tajuddin Chalid Hospital Makassar during the specified research period. After providing clarification and obtaining consent from eligible mothers, we collected a swab from the vaginal area. A PCR examination was conducted on the 167 maternal swabs that were received. Statistical analyses included frequency distribution using SPSS.Results: According to the study, 121 (72.5%) of the 167 samples tested positive for HPV type 6 DNA, while 46 (27.5%) tested negative. Meanwhile, 67% of 167 patients tested positive for HPV type 11 but were negative for the virus. Only 21 respondents with negative identification were found to be harboring both low-risk Human Papillomavirus types. In addition, 78 respondents received positive results for HPV types 6 and 11.Conclusion: Pregnant women can be infected with HPV types 6 and 11 even if they are asymptomatic. The high percentage of positive results suggests that routine maternal screening is recommended, especially during pregnancy.

Effect of Intermittent Fasting on Decreased Interleukin-6 Genes mRNA Expression in Mice (Mus Musculus) Herman, Sriyana; Muhammad Basir; Mochammad Hatta; Suryani As’ad; Ilhamjaya Patellongi; Ahmad Hadi Modi
Indonesian Andrology and Biomedical Journal Vol. 5 No. 2 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v5i2.65697

Nowadays, the development of various degenerative diseases is very rapid. The rapid development of the disease has encouraged the wider community to understand the impact. Intermittent fasting can help prevent the emergence of cancer (one of the degenerative diseases) because during fasting the body's cells are in protective mode so as to protect the body from disease. Intermittent fasting reduces the body's inflammatory status by inhibiting the expression of proinflammatory cytokines, especially interleukin-6 (IL-6). This study aims to examine the effect of intermittent fasting on IL-6 gene mRNA expression. This study is an experiment with Pretest-Posttest with Control Group design to examine the effect of intermittent fasting on the of IL-6 genes mRNA expression. The subjects of this study were 10 mice divided into 2 groups: the intermittent fasting group and the control group. The research was carried out at the Laboratory of Molecular Biology and Immunology Department, Faculty of Medicine, Universitas Hasanuddin, Makassar, as a place for the maintenance and care of experimental animals as well as examination of IL-6 genes mRNA expression. The study was conducted for 30 days. The results showed a decrease in the average value of IL-6 mRNA expression of subjects before and after intermittent fasting with the value of ρ = 0.003 (ρ <0.05) showed that there is a significant effect between intermittent fasting on the decrease in IL-6 genes mRNA expression. In conclusion, there is a decline in the IL-6 genes mRNA expression after intermittent fasting.

Positive Blood Culture Results Predominantly Unrevealed among Adults Patients with Sepsis Hursepuny, Valentine; Baedah Madjid; Firdaus Hamid; Mochammad Hatta; Muh. Nasrum Massi; Rizalinda Sjahril; Yoeke Dewi Rasita; Lisa Tenriesa; Andi Rofian Sultan
Alami Journal (Alauddin Islamic Medical) Journal Vol 8 No 1 (2024): JANUARY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/alami.v8i1.41777

Sepsis is increasing every year and can be life-threatening. In the diagnosis of sepsis, it is challenging to identify the causative agent of infection. This research aims to determine the proportion of positive blood culture in sepsis patients at Hasanuddin University Hospital, Makassar. Blood cultures were collected from 98 adult patients with sepsis manifestations. This research design is cross-sectional with a descriptive observation approach. The data analysed in descriptive statistics were utilised to summarise patient demographics, treatments, and outcomes. Thirteen of 98 samples were positive for microbial pathogens (13.26%). The elderly group had the highest percentage (76.5%); eighty-seven patients (88.77%) were treated with antibiotic therapy prior to blood culture collection. Cephalosporins are the most administered antibiotics (72.4%). Administration of empirical therapy prior to blood culture collection may decrease the sensitivity of culture results. The culture of the infectious focus should be done to assist in the consideration of antimicrobial treatment.

The Anticancer Activity of Ethanol Extract of Begonia medicinalis on Colorectal Cancer Rat Model Induced With 7,12-Dimethylbenz[A]Anthracene Guli, Musjaya; Ardiputra, Muh Akbar; Pitopang, Ramadanil; Sari, Retno; Hatta, Mochammad; Prawiro, Sumarno Reto; Saifah, Andi; Sardi, Bambang; Rahma, Rahma; Rahmawati, Nurul Dina
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.411

Colorectal cancer remains one of the leading causes of cancer-related deaths after lung cancer, highlighting the urgent need for more effective therapies with minimal side effects. Begonia medicinalis has been reported to have potential anticancer properties. This study aimed to evaluate the anticancer activity of Begonia medicinalis extract by assessing neutrophil concentration in a 7,12-dimethylbenz[a]anthracene (DMBA)-induced colorectal cancer rat model. The research employed a laboratory-based experimental approach with a post-test-only group design, comprising five groups with five replications each: treatment group I receiving a 25 mg/kg body weight, treatment group II receiving a 50 mg/kg body weight, treatment group III receiving a 100 mg/kg body weight, an normal group that was not DMBA-induced and did not receive therapy, and a negative control group that was DMBA-induced but did not receive therapy. The results of this study demonstrate that Begonia medicinalis extract effectively suppresses neutrophil concentration in a DMBA-induced colorectal cancer rat model. Treatment with 50 mg/kg body weight and 100 mg/kg body weight doses successfully reduced neutrophil cell levels in the experimental subjects, with the best results seen at the 100 mg/kg body weight dosage. This study provides new insights into the effects of plant-based therapies, Begonia medicinalis extract, in modulating the immune system by suppressing neutrophil concentration in a colorectal cancer rat model.

Analysis of Various Performance Factors Determining Rice Prices in East Java Province Hatta, Mochammad; Tjahjani, Ida Kusnawati
IJEBD (International Journal of Entrepreneurship and Business Development) Vol 8 No 5 (2025): September 2025
Publisher : LPPM of NAROTAMA UNIVERSITY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29138/ijebd.v8i5.3305

Purpose: This research aims to analyze various performance factors determining rice prices in East Java Province Design/methodology/approach: Quantitative data analysis in the form of production performance analysis, marketing analysis with a focus on performance analysis of each supply chain, development analysis and price formation analysis. Meanwhile, qualitative data analysis related to rice milling performance and yield as well as supporting descriptions of the various analyzes that have been carried out. Findings: The research results show that the price of rice is determined by various performances factors, namely production performance, marketing with a focus on performance of each supply chain, development and price formation, rice milling performance and yield as well as supporting descriptions Research limitations/implications: This study is limited to areas that have the same geographical conditions. Practical implications: This research is limited to areas that have similar geographical conditions. Originality/value: This research is original. Paper type: Case Study

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