Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Partner

REVIEW: RABIES VIRUS (RABV) DAN PATOGENESISNYA Maria Aega Gelolodo; Elisabet Tangkonda; Diana A. Wuri; Maxs U. E. Sanam
Partner Vol 28, No 2 (2023): Edisi November 2023
Publisher : Politeknik Pertanian Negeri Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35726/jp.v28i2.7104

Abstract

Rabies, caused by the rabies virus, is a zoonotic infection with a potentially deadly consequence. Both humans and animals are susceptible to this neurotropic virus. The rabies virus is typically present in infected animals' saliva and cerebral tissue, primarily canines, and transmits via bite wounds. Dogs are responsible for most human rabies transmissions, accounting for up to 99% of cases and consequently serving as the predominant contributor to human rabies mortality. This global threat kills approximately 59,000 people a year, with a death rate of nearly 100% in humans and animals. Fever, vomiting, anorexia, and lethargy are some of the non-specific early signs of rabies. Within days, symptoms escalate to deviant behaviour, brain dysfunction, paralysis, convulsions, hypersalivation, respiratory distress, and impaired swallowing. According to its immunological response, it proves that RABV can evade the initial immune defence. Hence, investigating the pathogenesis of RABV infection presents an intriguing study area. Key Words: Rabies, rabies virus, RABV, canine rabies, dog, pathogenesis, immunopathogenesis
Co-Authors Agnesia Endang Tri Hastuti Wahyuni Andriani Annytha Ina Rohi Detha Antin Yeftanti Nugrahening Widi Bambang Pontjo Priosoeryanto Bergita Soge Bili, Feny A. L. Cahyaningtyas, Dinda Eri Charles Rangga Tabbu Charles Rangga Tabu Denny Widaya Lukman Deta, Herlina Umbu Dewi Gaina, Cynthia Diana A. Wuri Diana A. Wuri Eky Melyani Sanu Filphin Adolfin Amalo Gaina, Cynthia D Gaina, Cynthia Dewi Herwin Pisestyani Jampur, Sesarius Wahyu Pagung Joesoef, Jayusman Arsiyanti Jois M. Jacob, Jois M. Kale, Maria Laurenci Fanny Permata Kallau, Novalino Harold Geoffrey Larry R.W Toha Laut, Meity M Loe, Fadhy Risckhy Loe, Fhady R. Loe, Fhady Risckhy Luji, Jovan Adiarsa Maha, Inggrid Trinidad Mandala, Graziela Angelicha Maria Aega Gelolodo Marlin Cindy Claudya Malelak Maxs U. E Sana Maxs Urias Ebenheizer Sanam Maya Shofa Meiko Kubo Murni, Theresia F. I. M. D. Naoaki Misawa Naoaki Misawai Ngadha L., Maria Emerentiana Ngasi, Bernadete Dwiyuni Novalino H. G Kallau Novian, Dede Rival Primatika, Roza Puspita, Anggi Putra Nugroho, Mega Perkasa Redempta Wea Roza Azizah Primatika, Roza Azizah Salestin, Ledy Chehfzy Sanam, Viona Mariana Dewi Satomi Sasaki Satoshi Sekiguchi Satria K. Frans Selan, Yulfia Nellymalik Simarmata, Yohanes T. R. M. R. Simarmata, Yohanes Timbun Raja Mangihut Ronael Soge, Bergitha Surachmi Setyaninigsih Takako Taniguchi Trinidad Maha, Inggrid Weakalla, Eugenia Raflesia Anjali Yasinta Widi, Antin Y. N. Widi, Antin Yeftanti Anggraeni Widodo Suwito Wuhan, Yustinus Oswin Primajuni Yeremia Yobellano Sitompul Yonas F Riwu Yulfia Nelymalik Selan, Yulfia Nelymalik