Article Per Year (5 Year)
p-Index From 2021 - 2026
5.298
P-Index
This Author published in this journals
All Journal ComEngApp : Computer Engineering and Applications Journal VALENSI JURNAL KIMIA SAINS DAN APLIKASI Jurnal Natur Indonesia Jurnal Riset Kimia SEMIRATA 2015 Jurnal Pengabdian UntukMu NegeRI Jurnal Surya Medika Jurnal CoreIT Indonesian Journal of Chemistry JURNAL PHOTON JURNAL PENDIDIKAN TAMBUSAI J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Building of Informatics, Technology and Science Zonasi: Jurnal Sistem Informasi AL - Mujaddid Jurnal Ilmu-ilmu Agama Journal of Computer System and Informatics (JoSYC) Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian kepada Masyarakat Nusantara Information System Journal (INFOS) KLIK: Kajian Ilmiah Informatika dan Komputer JUSTIN (Jurnal Sistem dan Teknologi Informasi) Dinamika Lingkungan Indonesia Makara Journal of Science Tsaqofah: Jurnal Penelitian Guru Indonesia Malcom: Indonesian Journal of Machine Learning and Computer Science Aurelia: Jurnal Penelitian dan Pengabdian Masyarakat Indonesia Jurnal Aplikasi IPTEK Indonesia AHKAM : Jurnal Hukum Islam dan Humaniora Mestaka: Jurnal Pengabdian Kepada Masyarakat Molekul: Jurnal Ilmiah Kimia Journal Of Artificial Intelligence And Software Engineering
Jasril Jasril
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

Published : 69 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 69 Documents
Search

 3   4   5   6   7 
Analisis Kualitatif Merkuri pada Beberapa Krim Pemutih Wajah yang Beredar di Pasar Tradisional Sentral Palopo: Qualitative Analysis of Mercury in Some Whitening Creams in the Traditional Market in Palopo Dampang, Hasria; Hurria, Hurria; Jasril, Jasril
Jurnal Surya Medika (JSM) Vol. 9 No. 3 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i3.6502

Abstract

Kosmetik merupakan bahan-bahan yang digunakan untuk memberikan efek kecantikan dan kesehatan bagi tubuh. Merkuri merupakan salah satu bahan aktif berbahaya yang sering ditambahkan dalam krim pemutih wajah yang dapat menyebabkan bintik-bintik hitam, alergi dan juga kanker kulit jika pemakaian dalam jangka panjang. Untuk mengetahui adanya merkuri (Hg) pada beberapa krim pemutih wajah yang beredar di pasar tradisional sentral palopo maka di lakukan pengujian menggunakan metode analisis kualitatif sebagai penentuan indikator warna. Sampel krim diambil dari 6 jenis merek yang berbeda yang diberi label A, B, C, D, E, F. Hasil pengamatan dari 6 sampel tersebut terdapat 2 sampel non-BPOM yang positif mengandung merkuri dan 1 sampel BPOM yang positif mengandung merkuri.
Studi Molecular Docking dan Evaluasi Farmakokinetik Senyawa Analog Pirazol Turunan Benzen-Sulfonilurea sebagai Inhibitor Enzim Aldose Reduktase and α-Glukosidase Menggunakan Pendekatan In Silico Fatisa, Yuni; Utami, Lisa; Syahri, Jufrizal; Jasril, Jasril; Lazulva, Lazulva
Jurnal Riset Kimia Vol. 15 No. 2 (2024): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i2.633

Abstract

The pyrazole scaffold modification in various chemical structures on several studies has shown various biopharmacological activities. This study aims to predict the potential inhibition of pyrazole analogs derived benzene-sulfonylurea (4A, 4B, 4E, 5A, 5C, 5D) against the α-glucosidase (3A4A) and aldose reductase (3RX2) enzymes based on a molecular docking approach using Molecular Operating Environment (MOE) 2020.0102 software and evaluate pharmacokinetic profile (ADMET). In this study, the six test compounds were obtained from previous studies that have been proven antihyperglycemic. The results showed that all the 3,5-disubstituted benzene-sulfonylurea derivative pyrazole analogs are predicted to have low inhibitory activity against the α-glucosidase enzyme. Further, all compounds showed good aldose reductase inhibitor activity and had lower binding free energy values ​​than tolrestat as the positive control (-6.82 kcal/mol). Compound 5C has the best potential inhibitory activity against the aldose reductase enzyme compared to the other test compounds, because it has the lowest binding free energy value (-8.76 kcal/mol) and interacts with important residues on the receptor forming four hydrogen bonds, namely the carbonyl group of SO2 with residues Trp111 and His110, and the carbonyl group of the amide with residues His110 and Tyr48, as well as 3 hydrophobic bonds, namely a pyrazole ring with residues Leu300, Trp219 and a furan ring with Phe122. ADMET properties of the compounds are also predicted. This information provides an opportunity for a 5C compound as an aldose reductase inhibitor agent to develop drug candidates with better and safer activities.
PEMBERDAYAAN UMKM MELALUI PEMANFAATAN LIMBAH KULIT NANAS MENDUKUNG GREEN ECONOMY DAN BISNIS BERKELANJUTAN Nofirda, Fitri Ayu; Hilma, Rahmiwati; Faladhin, Johan; Firmathoina, Aisyah; Fauzi, Faradiba Kamilia; Hamersat, Danu; Zikra, Nadila
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 5 (2024): Vol. 5 No. 5 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i5.35918

Abstract

Penelitian ini bertujuan untuk mengeksplorasi dan mengimplementasikan strategi pemberdayaan Usaha Mikro, Kecil, dan Menengah (UMKM) melalui pemanfaatan limbah kulit nanas di Desa Kualu Nenas, Kabupaten Kampar, sebagai bagian dari upaya mendukung green economy dan bisnis berkelanjutan. Metode yang diterapkan meliputi sosialisasi, pelatihan keterampilan, dan pendampingan dalam pengolahan limbah menjadi produk bernilai tambah, seperti sabun cair dan pupuk organik. Hasil dari program ini menunjukkan peningkatan signifikan dalam keterampilan anggota kelompok tani, yang berdampak pada peningkatan pendapatan dan daya saing produk di pasar. Selain itu, program ini berhasil meningkatkan kesadaran lingkungan di kalangan petani, yang kini lebih memahami pentingnya pengelolaan limbah untuk mengurangi dampak negatif terhadap ekosistem. Keberhasilan inisiatif ini tidak hanya memberikan manfaat langsung kepada peserta, tetapi juga membuka peluang untuk replikasi di komunitas lain, sehingga dapat memperluas dampak positif dalam konteks pembangunan berkelanjutan. Penelitian ini menegaskan pentingnya kolaborasi antara berbagai pihak, termasuk pemerintah dan lembaga pendidikan, untuk memastikan keberlanjutan dan skalabilitas program di masa depan.
Synthesıs and in Sılıco Studıes of 1,3,5-Trıaryl-2-Pyrazolıne Derıvatıves Contaınıng Chloro Substıtuent and Pyrrolıdıne Moıety Jasril, Jasril; Iktiarudin, Ihsan; Ulhukmi, Nisa; Novianty, Riryn; Syaifullah, Mhd Muslim; Frimayanti, Neni
Molekul Vol 21 No 1 (2026)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2026.21.1.11084

Abstract

ABSTRACT. Pyrazoline is a well-known group of five-ring heterocyclic compound containing two nitrogen atoms that has a wide range of promising biological activities. The aim of this research is to synthesize 1,3,5-triaryl-2-pyrazoline derivatives with chloro substituent and pyrrolidine moiety and to explore their potency as inhibitors for cervical cancer. The synthesis was performed through three-steps reactions. Firstly, synthesis of chlorinated naphthalenyl chalcones through Claisen-Schmidt condensation. Secondly, synthesis of chlorinated naphthalenyl pyrazolines through nucleophilic addition of phenylhydrazine to the chalcone and followed by intramolecular cyclization. Thirdly, synthesis of pyrazoline derivatives by adding the pyrrolidine moiety through O-alkylation reaction. Then, the in silico studies through molecular docking, ADME profiling, and toxicity prediction were performed to explore the potency of the synthesized compounds as inhibitors of cervical cancer by inhibiting the activity of Sirtuin-1 (SIRT-1) (PDB ID: 4I5I). The structure of all pyrazoline derivatives (4a-4c) were confirmed by spectroscopic analysis including UV, FT-IR, HRMS, and NMR. Based on the docking study, compound 4a with binding free energy of -12.59 kcal/mol exhibited better potency as SIRT-1 inhibitor than previously reported inhibitor (EX527). Then, based on the ADME profiling and toxicity prediction, it can be concluded that compound 4a exhibited reasonable drug properties with low toxicity potency (predicted LD50 = 1000 mg/kg). Keywords: : Cervical cancer, molecular docking, pyrazoline-pyrrolidine, pyrazoline synthesis, sirtuin-1
Pengaruh Model Pembelajaran Problem Based Learning Berbantuan Baamboozle terhadap Hasil Belajar Siswa pada Mata Pelajaran Informatika di Kelas XI SMA Negeri 2 Padang Panjang Salsabiela, Fadhilla; Marta, Rizkayeni; Jasril, Ilmiyati Rahmy; Zaus, Mahesi Agni
TSAQOFAH Vol 5 No 6 (2025): NOVEMBER
Publisher : Lembaga Yasin AlSys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/tsaqofah.v5i6.7753

Abstract

The issue of low student learning outcomes, particularly in Informatics subjects, remains a challenge in school-based learning processes. One potential solution is the use of instructional models that enhance student engagement, understanding, and motivation. This study aims to examine the effect of implementing the Problem Based Learning (PBL) model assisted by Baamboozle on students’ learning outcomes in Informatics at Grade XI of SMA Negeri 2 Padang Panjang. A quantitative method with a quasi-experimental design, specifically the Nonequivalent Control Group Design, was employed. The study population included all Grade XI students, with a sample of 72 students divided equally into an experimental class (36 students) and a control class (36 students). Data were collected through learning outcome tests and statistically analyzed. The results showed that the average post-test scores of the experimental class were higher than those of the control class. Data analysis confirmed a significant effect of the PBL model assisted by Baamboozle on the improvement of Informatics learning outcomes. These findings suggest that combining problem-based learning with educational game media such as Baamboozle can create a more engaging and interactive learning environment, positively impacting students’ academic achievement.
Synthesis and Molecular Docking Assay of 2-(3-3,4-dimethoxyphenyl)-6-oxopyridazin-1(6H)-yl)acetohydrazide as a candidate for breast anticancer Shalihah, Putri Mar Atus; Zulmy, Winda Permata; Hendra, Rudi; Jasril, Jasril
Photon: Jurnal Sain dan Kesehatan Vol. 16 No. 1 (2025): Journal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v16i1.9167

Abstract

Pyridazinones are a class of heterocyclic compounds with broad biological activities, one of which is as an anticancer. This study synthesized N-acetohydrazide substituted pyridazinone derivatives and evaluated their potential as breast cancer therapy through molecular docking studies. The target compound, 2-(3-(3-methoxyphenyl)-6-oxopyridazine-1(6H)-yl)acetohydrazide(3), was synthesized through three reaction steps: condensation to form the pyridqzinone core, functionalization of ethyl chloroacetate at the nitrogen position, and substitution of the ethoxy group with hydrazine hydrate. The yield obtained was 48.14%. The purity of the synthesized compound was confirmed through melting point determination and high-performance liquid chromatohraphy (HPLC) analysis, which showed a single dominant peak. Structural elucidation using Fourier-transform infrared (FTIR), mass spectrometry (MS), proton nuclear magnetic resonance (1H-NMR), and carbon-13 nuclear magnetic resonance (13C-NMR) verified the expected structure.  Molecular tethering studies against tyrosine kinase (PDB ID: 3ERT) showed that compound (3) has a binding free energy of -7.93 kcal/mol, with two hydrogen bonds formed with residues Glu353 and Leu387. These results indicate that compound (3) has not shown better inhibitory activity than tamoxifen. Nonetheless, this compound fulfils good physicochemical characteristics based on Lipinski's rule, so it remains promising for further development.
Integrasi Efficient Channel Attention (ECA) pada DenseNet169 untuk Klasifikasi Multi-Kelas Citra X-ray Dada: Integration of Efficient Channel Attention (ECA) in DenseNet169 for Multi-Class Chest X-ray Classification Satira, Husna; Negara, Benny Sukma; Irsyad, Muhammad; Jasril, Jasril; Agustian, Surya
MALCOM: Indonesian Journal of Machine Learning and Computer Science Vol. 6 No. 3 (2026): MALCOM July 2026
Publisher : Institut Riset dan Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57152/malcom.v6i3.2799

Abstract

Penyakit paru seperti pneumonia dan COVID-19 masih menjadi masalah kesehatan global yang memerlukan deteksi dini dan akurat. X-ray dada merupakan modalitas pencitraan yang umum digunakan, namun interpretasinya masih bergantung pada keahlian serta ketelitian radiolog. Penelitian ini bertujuan untuk mengevaluasi efektivitas integrasi Efficient Channel Attention (ECA) pada arsitektur DenseNet169 untuk klasifikasi multi-kelas pada citra X-ray dada. ECA dipilih karena merupakan mekanisme attention yang ringan serta mampu menangkap hubungan antarkanal fitur dengan kompleksitas parameter yang rendah. Dataset yang digunakan terdiri dari 5.228 citra yang terbagi ke dalam tiga kelas, yaitu COVID-19, pneumonia, dan normal. Penelitian ini membandingkan model DenseNet169 baseline dan DenseNet169 dengan ECA menggunakan parameter pelatihan yang sama untuk memastikan perbandingan yang adil. Evaluasi dilakukan menggunakan metrik accuracy, precision, recall, dan F1-score. Hasil menunjukkan bahwa model baseline memperoleh accuracy sebesar 96,75%, sedangkan model dengan ECA memperoleh 96,27%. Dengan demikian, integrasi ECA belum memberikan peningkatan performa yang signifikan dibandingkan dengan DenseNet169 pada dataset yang digunakan. Temuan ini menunjukkan bahwa efektivitas ECA dipengaruhi oleh karakteristik arsitektur model, strategi integrasi, serta karakteristik dataset, sehingga penerapan attention mechanism tidak selalu menghasilkan peningkatan performa secara langsung.
Pengembangan Sistem Klasifikasi Sentimen Berita PTPN IV Regional III Berbasis Web Menggunakan IndoBERT: Development of a Web-Based News Sentiment Classification System for PTPN IV Regional III Using IndoBERT Wahyudi, Diki; Insani, Fitri; Jasril, Jasril; Yusra, Yusra
MALCOM: Indonesian Journal of Machine Learning and Computer Science Vol. 6 No. 3 (2026): MALCOM July 2026
Publisher : Institut Riset dan Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57152/malcom.v6i3.2825

Abstract

Aktivitas pemantauan berita di Humas PTPN IV Regional III masih dilakukan secara manual sehingga memerlukan waktu yang lama, rentan terhadap subjektivitas, dan berisiko melewatkan informasi penting. Penelitian ini bertujuan untuk merancang dan membangun sistem pemantauan berita berbasis web yang mengintegrasikan model Indonesian Bidirectional Encoder Representations from Transformers (IndoBERT) untuk klasifikasi sentimen secara otomatis. IndoBERT dipilih karena dilatih khusus menggunakan korpus berbahasa Indonesia sehingga lebih mampu memahami karakteristik bahasa dan sentimen dibandingkan model multilingual. Dataset yang digunakan terdiri atas 1.200 berita dengan distribusi seimbang pada tiga kelas sentimen: positif, netral, dan negatif. Model dikembangkan menggunakan metode fine-tuning dan menghasilkan akurasi 75% serta macro F1-score 0,74. Kelas negatif memperoleh kinerja terbaik dengan F1-score 0,85, sedangkan kelas netral mencapai 0,63 akibat karakteristik sentimen yang ambigu. Sistem ini dikembangkan menggunakan Flask, Next.js, MySQL, dan SerpAPI. Hasil pengujian Black Box menunjukkan bahwa seluruh fitur berfungsi sesuai kebutuhan, sedangkan User Acceptance Testing (UAT) memperoleh tingkat penerimaan sebesar 96,5%. Penelitian ini berkontribusi melalui implementasi sistem pemantauan berita korporasi berbasis web yang mengintegrasikan IndoBERT secara end-to-end.
MONEY POLITICS: SOLUTIONS IN THE QURAN FROM A CONTEMPORARY INTERPRETATION PERSPECTIVE Syukri Daud; Ahmad Dusuki Daulay; Iqbal Maulana; Nizar Zulmi Hasibuan; Muhammad Ayyub Roy Tama; Jasril Jasril
Al - Mujaddid: Jurnal Ilmu-ilmu Agama Vol 7 No 1 (2025): Al - Mujaddid : Jurnal Ilmu-ilmu Agama
Publisher : STAI Sebelas April Sumedang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51482/almujaddid.v7i1.126

Abstract

The phenomenon of money politics is a form of deviation in the democratic process that contradicts the principles of justice and leadership integrity. This practice is widespread during elections, where votes are traded for personal or group gain. This study aims to analyze the money politics phenomenon from the perspective of the Qur’an, using a contextual interpretation of Surah Al-Baqarah verse 188. This qualitative research uses a library-based approach with thematic and contextual exegesis. The verse prohibits consuming others' wealth unjustly, including bribing authorities to gain something unlawfully, both legally and morally. The findings reveal that money politics is a form of injustice condemned by the Qur’an, as it damages the structure of social justice and violates the trust in leadership. Contextual interpretation offers a relevant understanding of the verse in relation to today’s socio-political dynamics.
Co-Authors - Aisyah - Nurlaili -, Sulismayati Abdul Aziz Adel Zamri Adel Zamri agistia, nesa Ahmad Dusuki Daulay Ahmad Fauzan Aisyah Aisyah Aisyah, - Akbar, Unggul Al Fiqri, M. Faiz Alfarabi.B, Alif Ananda, Sherly Anggita, Anggi Fisi Aprilia, Tasya Asmawati Asmawati Baehaqi Bintal Amin Christine Jose Christine Jose Dampang, Hasria Darian Alfatos Denai Wahyuni Desviana, Laila Dewi, Erna Puspita Elin Haerani Elka Yuslinda Elvia Budianita Elviyenti, Elviyenti Fadhilah Syafria Faladhin, Johan Fauzi, Faradiba Kamilia Fawrin, Heralda Febi Yanto Fernando, Rivan Fiffah, Chainul Firmathoina, Aisyah Fitri Insani Fitria Novitasari Frischa Meivilona Yendi Gusti, Siska Kurnia Haiyul Fadhli Hamersat, Danu Haresman, Haresman Hariansyah, Jul Hasmalina Nasution Hendra, Rudi Hilwan Yuda Teruna Hurria, Hurria Ihsan Ikhtiarudin Iis Afrianty Ikhtiaruddin, Ihsan Iktiarudin, Ihsan Illahi, Ridho Indah Wulandari Iqbal Maulana Isnaniar Iswantir M Jufrizal Syahri Laila Desviana Lazulva Lazulva, Lazulva Lestari Handayani Lisa Utami Mahesi Agni Zaus Marta, Rizkayeni Masykur HZ Masykur Hz Muhammad Ayyub Roy Tama Muhammad Irsyad Muhdarina Muhdarina Muhdarina Muliani, Sarifah Muslim Syaifullah, Mhd Nazir, Alwis Negara, Benny Sukma Neni Frimayanti Nizar Zulmi Hasibuan Nofirda, Fitri Ayu Novianty, Riryn Nuraini Ramadhani Nurhayati Nurlaili Nurlaili Nurlaili, - Nurwijayanti Pranata, Joni Prasetya Prasetya, Prasetya Putra, Ade Herdian Putra, Rido Putri, Atika Putri, Rahmayani Indah Rahayu, Anggi Putri Rahma Dona Rahmadini Syafri Rahmiwati Hilma Ramadhani, Eka Ramadhani, Siti Ramadhanti, Aulia Rizki Retno Hidayati Rudi Hendra Salsabiela, Fadhilla Sardi, Hajra Sari, Meidita Kemala Sari, Nila Puspita Satira, Husna Shalihah, Putri Mar Atus Silvera Devy Siregar, Sri Hilma Siregar, srihilma Soeci Izzati Adlya Sofyan Husein Siregar Sulismayati - Surya Agustian Suwanto Sanjaya Syaifullah, Mhd Muslim Syukri Daud Tri Windarti Tri Windarti Tria Harlianti Ulhukmi, Nisa Veithzal Rivai Zainal WAHYUDI, DIKI Wenni, Osriza Yan Guspriadi Yasthophi, Arif Yuana Nurulita Yuca, Verlanda Yuharmen - Yum Eryanti Yuni Fatisa Yusra, Yusra Zadrian Ardi Zikra, Nadila Zulmy, Winda Permata `Nasution, Hasmalina