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All Journal HAYATI Journal of Biosciences Medicina Sport and Fitness Journal E-Jurnal Medika Udayana Jurnal Veteriner Majalah Ilmiah Fisioterapi Indonesia Jurnal Ilmu Kedokteran (Journal of Medical Science) E-Jurnal Udayana Medica Indonesian Journal of Human Nutrition Majalah Kesehatan FKUB Jurnal Penelitian Pendidikan IPA (JPPIPA) ISM (Intisari Sains Medis) : Jurnal Kedokteran Interdental Jurnal Kedokteran Gigi (IJKG) Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indonesian Journal of Global Health research Bali Anatomy Journal Jurnal Ilmiah Medicamento Essential: Essence of Scientific Medical Journal Jurnal Kepelatihan Olahraga MAHESA : Malahayati Health Student Journal JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Hang Tuah Medical Journal Physical Therapy Journal of Indonesia Jurnal Kefarmasian Indonesia Jurnal Sains dan Kesehatan
Ni Made Linawati
Departemen Histologi, Fakultas Kedokteran Universitas Udayana, Denpasar, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal Veteriner

 1 
Pencegahan Gangguan Fungsi Ginjal Karena Stres Oksidatif pada Tikus Diabetes dengan Ubi Jalar Ungu I Made Jawi; I Wayan Sumardika; Ni Made Linawati
Jurnal Veteriner Vol 15 No 2 (2014)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Recently, anthocyanins-rich food, is believed to prevent tissue damages due to oxidative stress. This studyaimed to investigate the protective effect of water extract of Balinese purple sweet potatoes which containhigh anthocyanins to the renal tissues of diabetic rats. A total of 30 adult male rats were divided into threegroups using randomized post-test only control group design, respectivelly. Animals in group 1 (diabeticgroup) were given streptozotocin 60 mg/kg; group 2 (diabetic+extract/ treatment group) at 3 days after theanimals were given streptozotocin they were given 4 mL per day of the extract for 50, group 3 (control group)animals were given placebo. At day 50 of the treatment, the blood and renal tissue superoxidase dismutase(SOD) and malondialdehyde (MDA), creatinin and blood urea nitrogen (BUN) level of all rats were measured.The data were analyzed using analysis of variance. The results showed a significant increase of blood andrenal tissues MDA and BUN level in group 1 (p<0,05). In addition, a decrease of SOD and creatinin level(p<0,05) were also seen in this group. In comparison to animals in group 2, the increase of blood MDA andBUN level as well the decrease of SOD and, creatinin level were significantly lower (p<0,05). From thesefindings, it can be concluded that aqueous extract of Balinese purple sweet potato can prevent renalfunction disorders due to oxidative stress.
Perbedaan Gambaran Histopatologi Granuloma Paru Mencit Setelah Diinfeksi Mycobacterium tuberculosis dan atau Intervensi Silika (THE INFLUENCES OF TIME IN THE HISTOPATHOLOGY OF LUNG GRANULOMA IN MICE AFTER INFECTION OF MYCOBACTERIUM TUBERCULOSIS AND SILI Ni Made Linawati; I Gusti Ngurah Mayun; I Gusti Nyoman Sri Wiryawan; Nyoman Sri Budayanti; Ni Made Mertaniasih; Fedik Abdul Ratam; I Nyoman Wande; I Gusti Ayu Dewi Ratnayanti; Ida Ayu Ika Wahyuniari; I Wayan Sugiritama; I Gusti Kamasan Arijana
Jurnal Veteriner Vol 14 No 1 (2013)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

The characteristics of lung tuberculosis is granuloma, which is consisted of lymphocytes andmacrophages that show the interaction between immune cells and M.tb. Granuloma is the organizationprocess which is depend on lymphocytes invasion, adhesion molecules and chemokine fasilitation. Silicosiswhich is caused by silica, can influence granuloma in the lung. The features of granuloma is variationdepend on the elicited agent and immune reaction. The main purpose of this study was to prove thehistopathology differences of  mice lung granuloma caused by M.tb infection,  silica intervention and bothin 3th  and 7th weeks. It was 45 mice Balb-c strain, divided into 3 groups;  P1 got  M.tb infection with H37Rvstrain 105  perml,P2 got silica intervention with 60 micro litre and, P3 got both of M.tb infection and  silica intervention. Termination of each group were held on 3 and 7 weeks of intervention, continued byhistopathology examination. In the histopathology feature, we done semi-quantitative prosedure to measurelung damage by using Dormans scores; perivasculitis, peribronchiolitis, alveolitis and granuloma. Oneway anova to analysis the differences of histopathologycal result among these groups (P< 0,05).  Resultshowed the significant differences  among these group.  In the 3th weeks, we found  mild lung damage werehappened in all groups with granuloma, without necrosic (P1 and P2). In the 7th weeks we found  severe lungdamage in P3 with necrotic and fibrotic granuloma sign, with necrosis in P1, with fibrotic in P2.  Weconcluded the worst lung damage happened in 7th weeks in group which are got M.tb infection and silicaintervention, with granuloma characterictic of necrosic and fibrotic.
Penurunan Kadar Trigliserida pada Tikus Jantan dengan Terapi Growth Hormone (DECREASE OF TRIGLYCERIDE LEVEL IN MALE RAT BY GROWTH HORMONE TREATMENT) I Gusti Ayu Dewi Ratnayanti; I Wayan Sugiritama; Ida Ayu Ika Wahyuniari; Ni Made Linawati; I Gusti Ngurah Mayun; Dewa Ayu Agus Sri Laksemi; I Gusti Ngurah Sri Wiryawan; I Gusti Kamasan Nyoman Arijana
Jurnal Veteriner Vol 14 No 2 (2013)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

The use of growth hormone (GH) as cardiovascular disease treatment is still controversial. In thispreliminary study the effect of growth hormone therapy on plasma triglyceride level in dyslipidemia wasexamined. Pre and post control group design study was done using 20 dyslipidemic (total cholesterol >200mg/dL) male rats, age 11–12 month-old. The subjects were divided into four groups, aquadest (P0), GH0.02 IU/day (P1), GH 0.04 IU/day (P2), and GH 0.08 IU/day (P3). All subjects were given high cholesteroldiet for three weeks to achieve dyslipidemic in blood level. Aquadest and GH were injected subcutaneouslyonce daily for two weeks. Triglyceride plasma level was measured on day 22nd and 38th by using colorimetricenzymatic test. The mean of pre test plasma triglyceride level of all groups was 136.30 mg/dL and nosignificant difference was found among the groups (p > 0.05). Growth hormone therapy significantly reducedplasma triglyceride level of P1 by 11.78% (118.82 mg/dL, p < 0.01), P2 by 23.46% (103.41 mg/dL, p < 0.01),and P3 by 35.15% (90.22 mg/dL, p < 0.01). Comparison of  post test data amomg the groups showedsignificant difference (p < 0.01). This study show that growth hormone therapy could reduce plasmatriglyceride level in dyslipidemic rat. However, further research is needed to more understand the effect ofthe therapy on cardiovascular diseases.
Perbedaan Aktivitas Antimalaria Citrus maxima, Anredera cordifolia, Kombinasi Solanum lycopersicum-Malus domestica-Daucus carota pada Mencit Diinfeksi Plasmodium berghei) Dewa Ayu Agus Sri Laksemi; Luh Putu Ratna Sundari; Ni Luh Rustini; Ketut Tunas; Putu Ayu Asri Damayanti; I Made Sudarmaja; Ni Made Linawati
Jurnal Veteriner Vol 25 No 1 (2024)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/jveteriner.2024.25.1.103

Abstract

Resistensi obat malaria menyebabkan gejala berat dan kegagalan pengobatan. Untuk mengembangkan obat baru, dilakukan skrining terhadap beberapa tanaman yang berpotensi digunakan sebagai antimalaria. Penelitian ini bertujuan untuk memilih serta membandingkan aktivitas antimalaria Citrus maxima, Anredera cordifolia, Solanum lycopersicum, kombinasi Solanum lycopersicum-Malus domestica-Daucus carota pada mencit, Mencit Balb c jantan dibagi menjadi enam kelompok (n=5). Tanaman kering diekstraksi dengan cara maserasi menggunakan metanol 80%. Uji selama 4 hari dilakukan untuk memastikan efek antimalaria dari berbagai tanaman tersebut. Setelah diinokulasi dengan Plasmodium berghei, kelompok perlakuan diberi ekstrak sebanyak 1000 mg/kg, sedangkan DHP (Dihydroartemisinine Piperaquine) dan RPMI 5% berperan sebagai kontrol. Hasil penelitian menunjukkan semua ekstrak menunjukkan tingkat parasitemia lebih rendah dibandingkan dengan kontrol negatif. Penelitian ini menunjukkan persentase penekanan parasit sebesar 58.7, 84.3, 77.4, 61.4, dan 83.9 % untuk kombinasi Anredera cordifolia, Citrus maxima, Solanum lycopersicum, Solanum lycopersicum-Malus domestica-Daucus carota dan Dihydroartemisinine Piperaquine. Penekanan parasit tertinggi (84,3%) terdapat pada kelompok yang diberi ekstrak Citrus maxima. Ekstrak buah Citrus Maxima, Anredera Cordifolia, Solanum Lycopersicum-Malus Domestica-Daucus Carota mempunyai aktivitas antimalaria yang berbeda dengan Citrus maxima memilikipotensi terbaik sebagai antimalaria.
Co-Authors A.A.A. Biantari Apsari Trinaya ADNYANA PUTRA, I GEDE AGUS DIVA Adnyana, I Made Diatmika Agus Eka Darwinata Ali Djamhuri Amaral, Meriana Barreto Anak Agung Ngurah Subawa Arijana, I G Kamasan Nyoman Arijana, I Gusti Nyoman Kamasan Arijana, I.G Kamasan Nyoman Arijana, IGK Nyoman Bagus Komang Satriyasa Dakshayani Vijayan Dewa Agung Gina Andrini Dewa Ayu Agus Sri Laksemi Dewa Ayu Agus Sri Laksmi Dewa Putu Gede Purwa Samatra Dewi, Pande Putu Ayu Patria Etik Nurhidayati Eugenia Meidy Farmananda, Irsandi Rizki Febrina, Jessica Fedik Abdul Ratam Gede Wirata Harinder Kaur I Dewa Gede Angga Triadi Nata I Dewa Made Agus Paramarta Putra I Gde Haryo Ganesha I Gusti Ayu Artini I Gusti Ayu Dewi Ratnayanthi I Gusti Ayu Dewi Ratnayanti I Gusti Ayu Dewi Ratnayanti I Gusti Ayu Dewi Ratnayanti I Gusti Kamasan Arijana I Gusti Kamasan Nyoman Arijana I Gusti Kamasan Nyoman Arijana I Gusti Ngurah Mayun I Gusti Nyoman Sri Wiryawan I Gusti Nyoman Sri Wiryawan I Gusti Nyoman Sri Wiryawan I Ketut Tunas I Made Jawi I Made Krisna Dinata I MADE MULIARTA . I Made Niko Winaya I Made Sudarmaja I Made Sudarmaja I Nyoman Wande I Nyoman Wande I Putu Dema Prasetya I Wayan Juli Sumadi I Wayan Putu Sutirta Yasa I Wayan Rai Widarta I Wayan Sugiritama I Wayan Sugiritama I Wayan Sugiritama I Wayan Sumardika I.A.A. Widhiartini Ida Ayu Ika Wahyuniari Ida Bagus Putra Manuaba Intan Syahirah Bt Abdul Rauap Irmawan Farindra Jaspreet Kaur Juven Luvianto Ketut Ariawati Komang Ayu Trisnadewi Luh Made Indah Sri Handari Adiputra Luh Made Mas Rusyati Luh Putu Ratna Sundari Luvianto, Juven Muhammad Ashhabul Kahfi Mathar Mulianti, Rizki N. Adiputra Ni Eka Dewi Ambarawati Ni Eka Dewi Ambarawati Ni Kadek Ayu Satya Dewanti Ni Luh Gede Yoni Komalasari, Ni Luh Gede Yoni Ni Luh Rustini Ni Made Mertaniasih Ni Nyoman Sri Budayanti Ni Putu Candra Paramita Ni Wayan Arni Sardi Nuril Hidayah Nyoman Intan Cahaya Pertiwi Nyoman Pratiwi Hapsari Dewi Putu Ayu Asri Damayanti Putu Ayu Sita Saraswati Putu Diah Pratiwi Radjibu, Gabriela Anastasya Viorezky Rastika, I Gede Agus Ratnayanthi, I Gusti Ayu Dewi Ratnayanti, Gusti Ayu Dewi Raymond Elbert Budianto Riezky Januar Pramitha Ruthirar Kalaichelvam Sawitri, Anak Agung Sagung Sianny Herawati Sidauruk, Dona Uli Sugijanto - Sugijanto - Susy Purnawati Tjokorda Gede Oka Tohjiwa, G. Raditya Vania Lannisa Haestidyatami Wahyuddin, Wahyuddin Wicaksana, I Dewa Agung Gede Oka Dwi Widianti, I Gusti Ayu Widiyanti, I Gusti Ayu Wijaya, Debby Chesilya Wilianto Wilianto YASA, WAYAN PUTU SUTIRTA Yusuf Nasirudin