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All Journal HAYATI Journal of Biosciences Medicina Sport and Fitness Journal E-Jurnal Medika Udayana Majalah Ilmiah Fisioterapi Indonesia Jurnal Ilmu Kedokteran (Journal of Medical Science) E-Jurnal Udayana Medica Indonesian Journal of Human Nutrition Majalah Kesehatan FKUB Jurnal Penelitian Pendidikan IPA (JPPIPA) ISM (Intisari Sains Medis) : Jurnal Kedokteran Interdental Jurnal Kedokteran Gigi (IJKG) Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indonesian Journal of Global Health research Bali Anatomy Journal Jurnal Ilmiah Medicamento Essential: Essence of Scientific Medical Journal Jurnal Kepelatihan Olahraga MAHESA : Malahayati Health Student Journal JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Hang Tuah Medical Journal Journal of Pharmaceutical and Sciences. Physical Therapy Journal of Indonesia Jurnal Kefarmasian Indonesia Jurnal Sains dan Kesehatan

Ni Made Linawati

Departemen Histologi, Fakultas Kedokteran Universitas Udayana, Denpasar, Bali, Indonesia

Author-ID : 307586

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Pemberian ekstrak kulit buah anggur (Vitis vinifera L.) mampu menurunkan kadar malondialdehid (MDA) plasma pada tikus dengan diet tinggi kolesterol Etik Nurhidayati; Ni Made Linawati; I Wayan Sugiritama
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Introduction: High cholesterol levels will cause disease, one of which is cardiovascular disorders or diseases. Based on WHO data in 2012 there were 17.5 million deaths in the world due to cardiovascular disease. Coronary heart occupies the highest position at 42% where one of the most common risk factors is dyslipidemia. This research aimed to evaluate the effect of grape skin extract on plasma MDA level.Methods: This study is an experimental study with a post-test only control group research design. Thirty male Wistar rats aged 2-3 months with a body weight of around 200 grams and healthy, classified into 4 treatment groups and a control group with a high cholesterol diet and administration of different dosages of grape skin extract, dose of 100 mg/175 gbw (gram body weight), 250 mg/175 gbw, and 500 mg/175 gbw. All blood samples were taken on day 30 and an MDA test was performed. Kruskal Wallis test was performed to analyze the correlation.Results: The test results obtained with p<0.05 in the group of rats given grape skin extract at a dose of 100 mg/175 gbw, 250 mg/175 gbw, and 500 mg/175 gbw, thus showing significantly lower MDA levels compared with control group.Conclusion: Administration of grape skin extract to rats given a high cholesterol diet may reduce plasma MDA levels.Â Latar belakang: Kolesterol yang tinggi di dalam darah akan mengakibatkan berbagai masalah kesehatan, salah satunya adalah gangguan atau penyakit kardiovaskular. Data tahun 2012 terdapat 17,5 juta kematian di dunia karena masalah kardiovaskular. Jantung koroner menduduki posisi tertinggi yaitu 42% dimana salah satu faktor risiko terseringnya adalah dislipidemia. Mengetahui dampak pemberian kulit buah anggur terhadap MDA plasma tikus adalah sasaran penelitian ini.Metode: Sebuah penelitian eksperimental menggunakan metode post-test only diterapkan pada penelitian ini. Tiga puluh tikus wistar jantan, umur 2-3 bulan, berat rerata 200 gram, dan sehat, dikelompokkan ke dalam 1 kelompok kontrol serta 4 kelompok perlakuan dengan diet tinggi kolesterol dan pemberian dosis ekstrak kulit anggur yang berbeda-beda, yaitu dosis 100 mg/175 gbb, 250 mg/175 gbb dan 500 mg/175 gbb. Pada akhir penelitian, yaitu hari ke- 30, semua sampel diambil darahnya kemudian dilakukan uji MDA.Hasil: Uji penelitian dengan Kruskal Wallis memperoleh hasil p=0,035 (p<0,05) pada kelompok tikus yang diberikan ekstrak kulit anggur dengan dosis 100 mg/175 gbb, 250 mg/175 gbb dan 500 mg/175 gbb, sehingga menunjukkan kadar MDA lebih rendah signifikan dibanding dengan kontrol.Simpulan: Pemberian ekstrak kulit buah anggur memiliki dampak penurunan MDA plasma pada tikus dengan diet tinggi kolesterol.

Pengaruh teh kombinasi Euphobia milii dan Propolis terhadap fungsi ginjal tikus Wistar jantan I Dewa Made Agus Paramarta Putra; I Gusti Kamasan Nyoman Arijana; Ni Made Linawati
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Introduction. Indonesia has abundant natural resources that can be used as traditional medicine. For example, Euphorbia milii and Propolis. Euphorbia milii and Propolis have various benefits such as antioxidants, antibacterials, and immunomodulators. The toxic effects of the combination of Euphorbia milii and Propolis on renal function has not been studied. The purpose of this study was to determine the effects of the combination of Euphorbia milii and Propolis on the kidney function of male Wistar rats.Methods: This study was an experimental analytical study with a randomized post-test only control group design. Twenty-four male rats aged 2-3 months, body weight ± 200 grams were divided into 4 groups, namely; control group (standard feed + aquabidest), P1 (combination of Euphorbia milii and Propolis 40mg/100gram body weight (grbw) for 2 weeks), P2 (combination of Euphorbia milii and Propolis flower 40mg / 100grbw for 4 weeks), and P3 (combination of Euphorbia milii and Propolis flowers 40mg / 100grbw for 6 weeks).Results: Based on data analysis, the mean levels of blood urea nitrogen were not found to be significant between the control group, P2 and P3 from treatment groups, but there was a significant differences between P1 and the other three groups. The serum creatinine does not show significant difference among all the groups.Conclusion. The combination of Euphorbia milii and Propolis does not increase the the blood urea nitrogen and serum creatinine of the Wistar rat. Latar belakang. Indonesia memiliki kekayaan alam yang berlimpah yang dapat dimanfaatkan sebagai pengobatan tradisional. Misalnya tanaman Euphorbia milii dan Propolis. Euphorbia milii dan Propolis mempunyai beragam manfaat seperti antioksidan, antibakteri, dan imunomodulator. Efek toksik dari teh kombinasi Euphorbia milii dan Propolis terhadap fungsi ginjal belum pernah diteliti sebelumnya. Tujuan dari penelitian ini untuk mengetahui efek pemberian teh kombinasi dari bunga Euphorbia milii dan Propolis terhadap fungsi ginjal tikus Wistar jantan.Metode. Penelitian ini adalah penelitian analitik eksperimental dengan rancangan randomized post-test only, control group design. Dua puluh empat tikus wistar jantan berusia 2-3 bulan, berat badan ± 200 gram yang dibagi menjadi 4 kelompok, yaitu; kelompok kontrol (pakan standar + aquabidest), P1 (teh kombinasi bunga Euphorbia milii dan Propolis 40 mg/100 gram berat badan (grbb) selama 2 minggu), P2 (teh kombinasi bunga Euphorbia milii dan Propolis 40mg/100grbb selama 4 minggu), dan P3 (teh kombinasi bunga Euphorbia milii dan Propolis 40mg/100grbb selama 6 minggu).Hasil. Berdasarkan analisis data dari rerata kadar blood urea nitrogen (BUN) tidak ditemukan perbedaan yang signifikan antara kelompok kontrol dengan kelompok perlakuan P2 dan P3. Namun P1 menunjukan rerata yang lebih tinggi daripada kelompok lainnya. Pada kreatinin serum tidak terjadi peningkatan yang signifikan pada keempat kelompok.Simpulan. Pemberian teh kombinasi Euphorbia milii dan Propolis tidak menimbulkan peningkatan yang bermakna terhadap BUN dan kreatinin serum tikus Wistar.

Implementasi Sport Massage terhadap Penurunan Kelelahan Atlet Overall Ski Air Indonesia Ni Eka Dewi Ambarawati; I Made Jawi; Ni Made Linawati; Anak Agung Sagung Sawitri; I Made Krisna Dinata
Jurnal Kepelatihan Olahraga Vol 13, No 1 (2021)
Publisher : Fakultas Pendidikan Olahraga dan Kesehatan, Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jko-upi.v12i2.27190

Fatigue is a process of decreasing tolerance to physical activities. Metabolism burns energy where it breaks down carbohydrates to become lactic acid which results in fatigue. There are many ways to treat fatigue, such as sports massage. This research will guide the effect of sports massage on decreasing fatigue of Indonesia’s water ski athletes. Research method Treatment by Subject Design. The population of this study were all Indonesian athletes in overall water skiing who were still active in 2019. The subjects of the study were 18 Indonesian athletes of overall water skiing and divided into two different treatment periods. Period 1 was given sports massage treatment and Period 2 was given active rest treatment, between treatments was given a break for 3 days, so the research lasted for 5 days. Lactic acid measurement is measured by taking a blood sample and measured using an accurted lactate tool. Based on the test result, we find that the mean of lactic acid levels before sport massage and after active rest. When viewed from the average difference before and after sport massage treatment can be concluded that the sport massage treatment is more effective in reducing levels of lactic acid compared to active rest. Sport massage and active rest can both reduce levels of lactic acid, but sport massage is more effective than active rest. The suggestion in this study is that the trainers are expected to be able to provide a good recovery method after the athlete has done the exercise.

Ekstrak Etanol Ubi Jalar Ungu (Ipomea batatas L.) Menurunkan Kadar MDA Plasma Tikus Model Menopause I Wayan Sugiritama; I Gusti Ayu Dewi Ratnayanti; Ni Made Linawati; Ida Ayu Ika Wahyuniari; I Gusti Nyoman Sri Wiryawan; I Gusti Kamasan Nyoman Arijana
Indonesian Journal of Human Nutrition Vol. 9 No. 1 (2022)
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijhn.2022.009.01.5

Pemberian antioksidan merupakan salah satu strategi dalam manajemen menopause, karena diketahui bahwa stres oksidatif berkontribusi pada patogenesis penyakit yang terkait dengan menopause. Ubi jalar ungu diketahui memiliki aktivitas antioksidan karena kandungan flavonoidnya terutama antosianin. Tujuan dari penelitian ini adalah untuk mengevaluasi aktivitas antioksidan ubi jalar ungu kultivar Bali pada hewan model menopause, yang didahului dengan pengukuran kandungan flavonoid dan antosianin total, serta kapasitas antioksidan. Penelitian dengan rancangan post-test only control group design ini, menggunakan 28 ekor tikus Wistar betina yang diovariektomi bilateral. Hewan coba dibagi secara acak menjadi kelompok kontrol (P0), dan kelompok perlakuan (P1, P2, dan P3). Kelompok P1, P2, dan P3 diberi ekstrak etanol ubi jalar ungu (20mg/ml) per oral 7 hari setelah ovariektomi dengan dosis 1 ml, 2 ml, dan 4 ml/hari, sedangkan P0 diberikan saline 0,9% 1 ml/hari selama 30 hari. Sampel darah diambil untuk pengukuran MDA plasma dengan menggunakan metode reaksi asam tiobarbiturat. Penelitian ini menemukan kadar total flavonoid ekstrak ubi jalar ungu sebesar 676.9 mg/100g, kadar antosianin 56.78 mg/100g, dan kapasitas antioksidan 2516.82 mg/L GAEAC. Hasil analisis data menemukan terjadi penurunan kadar MDA plasma pada P1 (2,431±0,087 mol/L), P2 (2,174±0,096 mol/L), dan P3 (1,886±0,109 mol/L) dibandingkan dengan P0 (2,795± 0,063 mol/L) (p = 0,000). Kesimpulannya, ekstrak etanol ubi jalar ungu dapat menurunkan kadar MDA plasma tikus model menopause

POTENSI GASTROPROTEKTIF EKSTRAK BUNGA CENGKIH (Syzygium aromaticum): ANTIULKUS LAMBUNG, ANTIOKSIDAN, ANTIINFLAMASI, DAN ANTIMIKROBA Juven Luvianto; Ni Made Linawati; I Gusti Kamasan Nyoman Arijana; I Wayan Sugiritama
Essence of Scientific Medical Journal Vol 21 No 2 (2024): Volume 21 No. 2 (Juli - Desember 2023) Essential: Essence of Scientific Medical
Publisher : Kelompok Ilmiah Hippocrates Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/essential.v21i2.109987

Pendahuluan: Cengkih (Syzygium aromaticum) merupakan salah satu tanaman asli yang berasal dari Indonesia. Kandungan utama bunga cengkih adalah eugenol, ?-kariofilen, dan eugenol asetat. Gangguan pada sistem pencernaan atau gastrointestinal merupakan gejala ataupun penyakit yang menyebabkan ketidaknyamanan pada penderitanya, misalnya dispepsia, gastritis, maag, infeksi, konstipasi, perdarahan, ulkus lambung, dan penyakit degeneratif kronis yang dapat disebabkan oleh obat-obatan, minuman beralkolhol, merokok, makanan asam atau lemak tinggi, dan malnutrisi. Pembahasan: Aktivitas antiuklus lambung ekstrak bunga cengkih melalui peningkatan faktor protektif lambung seperti sintesis mukus lambung, bikarbonat, regulasi aliran darah mukosa lambung, serta menghibisi asam lambung. Ekstrak bunga cengkih juga berperan sebagai antioksidan dan antiinflamasi dengan mengurangi sitokin proinflamasi, misalnya IL-1?, IL-6, TNF-?, nitrogen oksida, NF-?B dan meningkatkan antioksidan seluler seperti P450 reduktase, superoksida dismutase, katalase, glutathion peroksida, gluthation, dan thiol non-protein. Aktivitas antimikroba ekstrak bunga cengkih meliputi antibakteri, antivirus, antifungi, dan antiprotozoa. Simpulan: Ekstrak bunga cengkih memiliki berbagai aktivitas biologis, seperti antiulkus lambung, antibakteri, antifungi, antiinflamasi, dan antioksidan. Introduction: Clove (Syzygium aromaticum) is one of Indonesia’s native plant. The main components of clove bud are eugenol, ?-caryophyllene, dan eugenol acetate. Gastrointestinal symptoms or disease can lead to patient feeling uncomfortable. For examples dyspepsia, gastritis, infection, constipation, bleeding, gastric ulcer, and chronic degenerative disease that may be caused by drugs, alcohol, smoking, acidic or fatty foods, and malnutrition. Discussion: Clove bud extract has a lot of biological activities such as, antiulcer, antibacterial, antifungal, antiinflammation, and antioxidant. The methods used for this literature review are from 41 journals and electronic databases search. The antiulcer component of clove bud extract works by increasing the gastric protective factor, such as synthetizing gastric mucous, bicarbonate, regulating gastric mucosal blood flow, and inhibiting gastric acid. Clove bud extract also plays a role as antioxidant and antiinflammation by reducing cytokines proinflammation like IL-1?, IL-6, TNF-?, nitrite oxide, NF-?B and enhancing cellular antioxidant, for example P450 reductase, superoxide dismutase, catalase, glutathione peroxidase, glutathione, thiol non-protein. The microbial activity of clove bud extract includes antibacterial, antiviral, antifungal, and antiprotozoal. Conclusion: Clove bud extract has several biological activity, such as antiulcer, antimicrobial, antibacterial, antifungal, antiinflammation, and antioxidant.

Efek Blueberry (Vaccinium sp.) Terhadap Kelembapan Kulit yang Terpapar Sinar Ultraviolet Akut ADNYANA PUTRA, I GEDE AGUS DIVA; IDA AYU IKA WAHYUNIARI; NI MADE LINAWATI; I GUSTI KAMASAN NYOMAN ARIJANA
Hang Tuah Medical Journal Vol 21 No 1 (2023): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v21i1.337

Introduction: Maintained skin moisture is an indication of healthy skin. Acute UV exposure can cause sunburn, which is characterized by a loss of moisture in the skin. Polyphenol compounds are one practical approach to protecting the skin from sunburn so that skin moisture is maintained. Blueberries are one of the natural ingredients consists of anthocyanin compounds, which are polyphenols from the flavonoid group. Aims: To determine the effect of blueberries on skin moisture exposed to acute ultraviolet rays. Methods: Literature study using references in the form of research articles and literature reviews from national and international journals and related books published in the last 10 years. In writing this literature review, 42 references were used which were accessed through Google Scholar, NCBI, Crossref, and Pubmed. Results: Blueberries anthocyanins can maintain skin moisture from increased transepidermal water loss (TEWL) due to acute UV ray exposure by reducing the formation of UV stimulated reactive oxygen species (ROS) and lipid peroxidation in keratinocyte cells to maintain the elastic modulus and mechanical properties of keratinocytes as well as can prevent sunburn by reducing the skin's modulation of UV exposure. However, the absorption of anthocyanin compounds in the intestine is so low that taking blueberries orally alone is not enough to achieve good biodistribution. Conclusion: Blueberries affect retaining moisture in skin exposed to acute UV rays, so they have the potential to be used as skincare ingredients. However, further research needs to be done, especially to determine the side effects that can be caused and the required extract concentration.

PENGARUH INFUSA TEH HIJAU (CAMELLIA SINENSIS) TERHADAP DIAMETER NODULUS LIMFATIKUS LIMPA MENCIT (MUS MUSCULUS) YANG DIPAPAR ROKOK ELEKTRIK Sidauruk, Dona Uli; Wahyuniari, Ida Ayu Ika; Linawati, Ni Made; Arijana, I Gusti Kamasan Nyoman
E-Jurnal Medika Udayana Vol 13 No 5 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i05.P05

E-cigarettes are the most widely used nicotine replacement therapy (NRT), particularly among young people. Exposure to e-cigarette vapor increases free radicals and suppresses the body's immune system. The accumulation of reactive oxygen species (ROS) in the spleen causes inflammation and tissue injury that decreases immune reactivity. It causes changes in the histoarchitecture of the spleen, including the lymphatic nodules. It might be repaired by the antioxidant and immunomodulatory activity of green tea that stimulates and enhances the immune system. Green tea polyphenols affect the production of cytokines along with the activation, proliferation, and differentiation of lymphocytes in the body. Increasing the diameter of the lymphatic nodules is an indicator of the immunomodulatory activity of green tea in mice exposed to e-cigarette vapor. The study design was a randomized post-test only controlled group with 27 sampled mice divided randomly into 3 groups, namely; P0 (e-cigarette vapor), P1 (e-cigarette vapor + green tea 0.020 g/bb/day), and P2 (e-cigarette vapor + green tea 0.040 g/bb/day). There were significant differences between the control and treatment groups, while between green tea doses of 0.020 g/bb/day and 0.040 g/bb/day was no significant difference. The study showed green tea infusion with an optimal dose of 0.020g/bb/day affected increasing the diameter of the spleen lymphatic nodules of mice exposed to e-cigarette vapor. Further research based on the difference in duration of infusion exposure and overall observation of the white pulp component are needed. Keywords : Green tea infusion, Lymphatic nodules, E-cigarette vapor.

PENGARUH PEMBERIAN THE EUPHORBIA MILII DAN PROPOLIS TERHADAP GAMBARAN HISTOLOGIS GINJAL TIKUS WISTAR JANTAN Wicaksana, I Dewa Agung Gede Oka Dwi; Linawati, Ni Made; Arijana, IGK Nyoman; Ratnayanti, I Gusti Ayu Dewi
E-Jurnal Medika Udayana Vol 11 No 3 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i03.P03

ABSTRACT Introduction: There are various kinds of traditional medicine in Indonesia, either derived from animals or from plants. One of kind traditional medicine that can be found in Indonesia are Euphorbia milii and propolis which has benefits as an immunomodulator and as an antioxidant. The use of traditional medicine with uncertain doses and time intervals may cause some adverse effects. The main purpose of the study is to know the effect of tea which made from Euphorbia milii and propolis on the histological appearance of the kidney of male wistar rats. Methods: This study used a randomized post test only controlled group. There are 4 groups of rats were taken from total 24 male wistar rats with an age range 2-3 months and a bodyweight ± 200 grams. The controlled group (K) was given aquabidest, the intervention group (P1-P3) was given the tea of Euphorbia milii and propolis, then terminated and continued with histological examination by measuring the diameter of the glomerulus. Data analysis technique is One Way Anova and Post Hoc with LSD test. Result: Based on the result of data analysis, the difference between the controlled group (K) and the intervention group (P1-P3) was not significant. Conclusion: Based on the result, the conclusion is that the tea of Euphorbia milii and propolis did not cause significant damage to the kidneys of male wistar rats. Keywords : Euphorbia milii, propolis, glomerulal diameter

POTENTIAL OF GREEN TEA INFUSION IN REDUCING LUNG MDA LEVELS OF BALB/C MICE DUE TO EXPOSURE TO ELECTRIC CIGARETTE VAPOR Adnyana, I Made Diatmika; Wahyuniari, Ida Ayu Ika; Linawati, Ni Made; Arijana, I Gusti Kamasan Nyoman
E-Jurnal Medika Udayana Vol 13 No 8 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i08.P01

This research aims to evaluate the potential of green tea infusion in reducing Malondialdehyde (MDA) levels in the lungs of mice exposed to electronic cigarette vapor. The research employed an experimental method with a Randomized Post-Test Only Control Group design. The research sample consisted of 20 male mice aged 3-4 months with an average weight of 30 grams, divided into four groups: normal group (CN), negative control (NC), treatment 1 with a dosage of green tea 0.03 g (T1), and treatment 2 with a dosage of green tea 0.06 g (T2). After the treatment, an analysis of MDA levels in the mice's lungs was conducted by TBARS test. The average levels of MDA in mice were obtained as follows: CN=12.669 µM, NC=23.940 µM, T1=10.997 µM, T2=14.395 µM. Statistical analysis using the One-Way ANOVA test revealed significant differences (p<0.05) between CN and NC, NC and T1, and NC and T2. These findings indicate that green tea infusion has the potential to reduce MDA levels in the lungs of mice exposed to electric cigarette vapor. Thus, this research provides a foundation for further studies regarding optimal dosage and the mechanism of action of green tea infusion in combating the negative effects of exposure to electronic cigarette vapor on respiratory organs.

PENGARUH PEMBERIAN EKSTRAK BUAH BIT (Beta vulgaris L) DAN UBI JALAR UNGU (Ipomoea batatas) TERHADAP KADAR TRIGLISERIDA PADA TIKUS DENGAN DIET TINGGI LEMAK Radjibu, Gabriela Anastasya Viorezky; Wahyuniari, Ida Ayu Ika; Linawati, Ni Made; Arijana, I.G Kamasan Nyoman
E-Jurnal Medika Udayana Vol 12 No 10 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i10.P18

Antioksidan betalain dan betasianin yang terkandung dalam Beta vulgaris L menurunkan kadar kolesterol dan trigliserida dalam darah. Demikian juga dengan kandungan antosianin dalam Ipomoea batatas untuk menurunkan kadar glukosa dan trigliserida dalam darah. Penelitian ini dilakukan untuk menguji pengaruh kombinasi antioksidan dari ekstrak Beta vulgaris dan Ipomoea batatas terhadap kadar trigliserida pada tikus wistar ( Rattus norvegicus ). Penelitian ini merupakan penelitian ekperimental melalui uji laboratorium. Rancangan penelitian yang digunakan adalahTrue Experimental Post Test Only Control Group Design . Subjek penelitian menemukan 24 ekor tikus wistar ( Rattus norvegicus ), yang terbagi ke dalam 4 kelompok penelitian. Data dianalisis dengan SPSS versi 16.0. Penelitian ini merupakan penelitian awal yang mengkombinasikan 2 (dua) ekstrak umbi yaitu Beta vulgaris L dan Ipomoea batatas, yang hasilnya berbeda dengan hasil penelitian yang telah dilakukan oleh peneliti-peneliti sebelumnya yang hanya mengamati pengaruh satu ekstrak umbi terhadap kadar trigliserida wistar. Hasil uji One-Way ANOVA menunjukkan bahwa tidak terdapat perbedaan signifikan di dalam kelompok maupun di antara kelompok kontrol, perlakuan 1, perlakuan 2, dan perlakuan 3, dengan demikian hipotesis yang diterima dalam penelitian ini adalah H0 yaitu kombinasi ekstrak Beta vulgaris L dan Ipomoea batatas dosis 10,8 mg/200grBB tidak berpengaruh terhadap kadar trigliserida pada tikus wistar. Kata kunci : ekstrak Beta vulgaris L, ekstrak Ipomoea batatas , trigliserida

Co-Authors A.A.A. Biantari Apsari Trinaya ADNYANA PUTRA, I GEDE AGUS DIVA Adnyana, I Made Diatmika Agus Eka Darwinata Ali Djamhuri Amaral, Meriana Barreto Anak Agung Ngurah Subawa Arijana, I G Kamasan Nyoman Arijana, I Gusti Nyoman Kamasan Arijana, I.G Kamasan Nyoman Arijana, IGK Nyoman Bagus Komang Satriyasa Dakshayani Vijayan Dewa Agung Gina Andrini Dewa Ayu Agus Sri Laksemi Dewa Ayu Agus Sri Laksmi Dewa Putu Gede Purwa Samatra Dewi, Pande Putu Ayu Patria Etik Nurhidayati Eugenia Meidy Febrina, Jessica Fedik Abdul Ratam Gede Wirata Harinder Kaur I Dewa Gede Angga Triadi Nata I Dewa Made Agus Paramarta Putra I Gde Haryo Ganesha I Gusti Ayu Artini I Gusti Ayu Dewi Ratnayanthi I Gusti Ayu Dewi Ratnayanti I Gusti Ayu Dewi Ratnayanti I Gusti Ayu Dewi Ratnayanti I Gusti Kamasan Arijana I Gusti Kamasan Nyoman Arijana I Gusti Kamasan Nyoman Arijana I Gusti Ngurah Mayun I Gusti Nyoman Sri Wiryawan I Gusti Nyoman Sri Wiryawan I Gusti Nyoman Sri Wiryawan I Ketut Tunas I Made Jawi I Made Krisna Dinata I MADE MULIARTA . I Made Niko Winaya I Made Sudarmaja I Made Sudarmaja I Nyoman Wande I Nyoman Wande I Putu Dema Prasetya I Wayan Juli Sumadi I Wayan Putu Sutirta Yasa I Wayan Rai Widarta I Wayan Sugiritama I Wayan Sugiritama I Wayan Sugiritama I Wayan Sumardika I.A.A. Widhiartini Ida Ayu Ika Wahyuniari Ida Bagus Putra Manuaba Intan Syahirah Bt Abdul Rauap Irmawan Farindra Irsandi Rizki Farmananda Jaspreet Kaur Juven Luvianto Ketut Ariawati Komang Ayu Trisnadewi Luh Made Indah Sri Handari Adiputra Luh Made Mas Rusyati Luh Putu Ratna Sundari Luvianto, Juven Muhammad Ashhabul Kahfi Mathar N. Adiputra Ni Eka Dewi Ambarawati Ni Eka Dewi Ambarawati Ni Kadek Ayu Satya Dewanti Ni Luh Gede Yoni Komalasari, Ni Luh Gede Yoni Ni Luh Rustini Ni Made Mertaniasih Ni Nyoman Sri Budayanti Ni Putu Candra Paramita Ni Wayan Arni Sardi Nuril Hidayah Nyoman Intan Cahaya Pertiwi Nyoman Pratiwi Hapsari Dewi Putri, Ni Putu Windi Sukma Putu Ayu Asri Damayanti Putu Ayu Sita Saraswati Putu Diah Pratiwi Radjibu, Gabriela Anastasya Viorezky Rastika, I Gede Agus Ratnayanthi, I Gusti Ayu Dewi Ratnayanti, Gusti Ayu Dewi Raymond Elbert Budianto Riezky Januar Pramitha Rizki Mulianti Ruthirar Kalaichelvam Sawitri, Anak Agung Sagung Sianny Herawati Sidauruk, Dona Uli Sugijanto - Sugijanto - Susy Purnawati Tjokorda Gede Oka Tohjiwa, G. Raditya Vania Lannisa Haestidyatami Wahyuddin, Wahyuddin Wicaksana, I Dewa Agung Gede Oka Dwi Widianti, I Gusti Ayu Widiyanti, I Gusti Ayu Wijaya, Debby Chesilya YASA, WAYAN PUTU SUTIRTA Yusuf Nasirudin

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