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All Journal Jurnal Anestesiologi Indonesia Althea Medical Journal MAJALAH ILMIAH WIDYA Biology, Medicine, & Natural Product Chemistry Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati YARSI Medical Journal Majalah Kesehatan Pharmamedika Majalah Sainstekes Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Science Midwifery Indonesian Journal of Global Health research Babali Nursing Research Medicra (Journal of Medical Laboratory Science/Technology) Medical Scope Journal (MSJ) JOURNAL LA MEDIHEALTICO Jurnal Locus Penelitian dan Pengabdian JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Info Abdi Cendekia Jurnal Indonesia Sosial Sains Junior Medical Journal Eduvest - Journal of Universal Studies Jurnal Ruhul Islam
Diniwati Mukhtar
Faculty Of Medicine, Yarsi University, Jakarta, Indonesia
Religion Aerospace Engineering Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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The Relationship Between Smoking Habits Among Pneumonia Patients and Length of Hospitalization Tiara Anisyah Harahap; Qomariah RS; Diniwati Mukhtar
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.3155

Abstract

Pneumonia is a respiratory tract infection caused by viruses, fungi or bacteria. The impact of pneumonia can be measured by the length of stay (LOS) in the hospital. One of the risk factors for pneumonia is smoking. Given the high prevalence of smokers in Indonesia, this study aims to examine the correlation between smoking habits and the duration of the length of stay in pneumonia patients at RSUD dr. Chasbullah Abdulmadjid Bekasi city. This study used an analytical observational design with cross sectional approach. The research population was pneumonia patients at RSUD dr. Chasbullah Abdulmadjid, with a total of 122 patients obtained through consecutive sampling. Secondary data from patients medical record were used. Data analysis was performed using the Chi Square statistical test to determine the relationship between variables. Out of 122 patients, it was found that 50.8% (62 patients) were non smokers and 42.2% (60 patients) were active smokers. The distribution of length of stay shows that 73.8% of patients had a short length of stay category. The Chi Square test result indicated a significant relationship between smoking habits and the length of stay in pneumonia patients (P – Value 0.000). There is a statistically significant relationship between smoking habits and length of stay (LOS) in pneumonia patients.
Overview of Elderly Risk Factors on Symptoms and Severity of Community-Acquired Pneumonia Using the PSI Score Muren Dhianisa Dzakirah; Qomariah RS; Diniwati Mukhtar
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.3156

Abstract

Community-acquired pneumonia is a major cause of morbidity and mortality, particularly among the elderly. Age-related physiological changes, immune decline, and comorbidities may influence clinical manifestations and disease severity. Assessment of pneumonia severity using the Pneumonia Severity Index (PSI) is essential for appropriate clinical management. This study was an observational analytic study with a retrospective cross- sectional design using medical record data of elderly patients with community- acquired pneumonia at RSUD dr. Chasbullah Abdulmadjid, Bekasi, from May 2024 to April 2025. A total of 73 patients were selected using consecutive sampling. Data were analyzed using univariate and descriptive. Most patients were classified as elderly aged 60–74 years. The most common symptoms were cough and shortness of breath. Based on the PSI score, most patients had low to moderate pneumonia severity, while only a small proportion had severe pneumonia.Most patients were classified as elderly aged 60–74 years. The most common symptoms were cough and shortness of breath. Based on the PSI score, most patients had low to moderate pneumonia severity, while only a small proportion had severe pneumonia.
Cytokine-Mediated Systemic Inflammation in Patient with Sepsis in ICU: A Systematic Literature Review and Meta- Analysis of Interleukin-6 and Tumor Necrosis - Yusuprihastuti, Maulitia Neny; Juniarti, Juniarti; Weni, Linda; Mukhtar, Diniwati; Satoto, Hari Hendriarto
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.82097

Abstract

ABSTRACTObjectives: To systematically evaluate and quantify the prognostic value of circulating interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels for mortality and disease severity in adult intensive care unit (ICU) patients with sepsis.Study design: This study was conducted as a systematic review and meta-analysis of observational studies and randomized controlled trials. Evidence quality was assessed using the Newcastle–Ottawa Scale for observational studies. Quantitative synthesis was performed using meta-analytic techniques.Data sources: A comprehensive literature search was performed in PubMed, Scopus, Web of Science, and Embase from database inception to the most recent available date. Reference lists of relevant articles were also manually screened to identify additional eligible studies.Data synthesis: Two studies evaluating IL-6 (196 ICU sepsis patients) demonstrated significantly higher IL-6 levels in non-survivors compared with survivors, with a large and consistent pooled effect size (SMD −1.92; 95% CI −2.27 to −1.57) and no interstudy heterogeneity, supporting IL-6 as a robust prognostic biomarker. TNF-α data from two studies (270 patients) also showed significantly elevated levels in non-survivors (SMD −2.70; 95% CI −3.05 to −2.35); however, substantial heterogeneity and slight funnel plot asymmetry reduced the certainty and generalizability of its prognostic value.Conclusions: Elevated IL-6 and TNF-α levels are associated with increased mortality in ICU patients with sepsis. IL-6 demonstrates more consistent and reliable prognostic performance, supporting its use for early risk stratification in critical care, whereas TNF-α may serve as a complementary biomarker.Registration: This systematic review and meta-analysis was conducted in accordance with PRISMA guidelines. Prospective registration in the PROSPERO database.Keywords:interleukin-6; intensive care unit; mortality; sepsis; tumor necrosis factor-α
Co-Authors Aan Royhan Aan Royhan Aan Royhan Afifah Herlianti, Lucy Ainur Rahmah, Nunung Alqudsi, Hade Irhas Amsaka, Azha Azzuna Anisya Fitriah Astalia Maisya Adhitama Astuti Giantini Awairaro, Tirsa Persila Budiman, Dicky Dewi, Intan Keumala Dian Noor Aristi Dicky Wahyudi Dita Safira Dita Safira Salsabila Endah purnamasari Endang Purwaningsih Endang Purwaningsih Endy Muhammad Astiwara Endy Muhammad Istiwara Ernanda, Hafid Fachry Abda El Rahman Fadilah , Fadilah Fadilah Fadilah, Fadilah Farah Zahida Fatimah Eliana Taufik Febri Irwansyah Fenie Oktafiani Budi Ferlianti, Rika Fitriani, Hasna L. Haddad, Desi Ariyani Hakim, Jasir Hari Hendriarto Satoto Hasna Luthfiah Hasna Luthfiah Fitriani Hasna Luthfiah Fitriani Helwiah Umniyati Himmi Marsiati Himmi Marsiati Hutabarat, Andrea Ivana Allicia Intan Keumala Dewi Irfan Syarif, Irfan Juniarti Juniarti Karina A Ridwan Karina Ajeng Ridwan Lelosutan, Syafruddin Lena Fitriyana Linda Weni Linda Weni M Arsyad M Istiwara, Endy Ma'sum, Ali Maharsi, Eri Dian Manik, Sabarina Elfrida Marsiati, Himmi Melasari Marantika Melia Puji Pratami Muhammad Arsyad Muhammad Iqbal Thamrin Muhammad Samsul Mustofa Muren Dhianisa Dzakirah Mustofa, M Samsul nafizha Naila Nur Fauziah Novia Suci Ramadhanti Nunung Ainur Rahmah Nursabur, Bistamy Muhammad Nurwijayanti Pd, Fanny Ratnasari Prameswari, Keisa Yude prastina sari, Putri Agnia Pratiwi Pujilestari Sudarmono Puspita, Switania Putri Putra Pangraizan, Farel Q Qomariyah Qomariah RS Qomariyah Qomariyah Qomariyah Sachrowardi Retno Noviar Dhani Ridwan, Karina A. D. A. Ridwan, Karina Ajeng Sakura Muhammad Tola Samsul Mustofa, Muhammad Siti Helmyati Sri Wuryanti Sudarmono, Pratiwi Pudjilestari Susmiarsih Panjiasih, Tri Taufik, Fatimah Eliana Tiara Anisyah Harahap Tjandra Yoga Aditama Tunru, Insan Sosiawan Tw, Afrizal Wan Nedra Widiastari, Erina Febriani Yulia Suciati Yusnidar, Amirah Yusuprihastuti, Maulitia Neny