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All Journal Jurnal Pendidikan Ekonomi (JUPE) Jurnal Pendidikan Teknik Mesin Swabumi (Suara Wawasan Sukabumi) : Ilmu Komputer, Manajemen, dan Sosial Jurnal Pendidikan UNIGA AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat JURNAL MUQODDIMAH : Jurnal Ilmu Sosial, Politik dan Hummaniora Konvergensi Jurnal Inovasi Teknik Kimia Al-Syakhsiyyah : Journal of Law and Family Studies Community Development Journal: Jurnal Pengabdian Masyarakat Academia Open AGRISCIENCE Prophetic Law Review TAJDID: Jurnal Pemikiran Keislaman dan Kemanusiaan Devotion: Journal of Research and Community Service Jurnal Pengabdian kepada Masyarakat PROFESSIONAL HEALTH JOURNAL Ma'mal: Jurnal Laboratorium Syariah dan Hukum Empowerment Society Proceedings Series on Physical & Formal Sciences IJCR (Indonesian Journal of Chemical Research) YASIN: Jurnal Pendidikan dan Sosial Budaya Konseling At-Tawazun : Jurnal Kajian Bimbingan dan Konseling Islam Jurnal Farmasetis Innovative: Journal Of Social Science Research Prosiding Seminar Riset Mahasiswa Jurnal Penelitian Gudang Jurnal Multidisiplin Ilmu Jurnal Relasi Publik Jurnal Akuntansi, Keuangan, Perpajakan dan Tata Kelola Perusahaan GEMBIRA (Pengabdian Kepada Masyarakat) Finance Jurnal Pengabdian Masyarakat Manfaat: Jurnal Pengabdian Pada Masyarakat Indonesia Journal of Indonesian Constitutional Law JURNAL INSAN CENDEKIA Senadika
Ainun Najib
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Journal : PROFESSIONAL HEALTH JOURNAL

 1 
Reducing blood uric acid levels after drinking Annona muricata linn (soursop leaf) extract: study in elderly with hyperuricemia Muhammad Al Amin; Ainun Najib; Ali Syahbana; Efina Amanda
PROFESSIONAL HEALTH JOURNAL Vol. 6 No. 1 (2024): December
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v6i1.788

Abstract

Introduction: Gout is a degenerative disease that often attacks joints, especially in older adults. This disease is caused by the buildup of uric acid crystals in the joints, which causes inflammation and severe pain. One of the main indications that someone suffers from gout is if the results of measuring the uric acid level in the blood are more than 7.0 (mg/dL), whereas in women, it is more than 5.7 mg/dL. Objectives: Research to determine the effectiveness of A. Muricata leaf extract in reducing uric acid levels in older adults with hyperuricemia. Methods: Quantitative research, using a quasi-experimental type with Pre-test, Post-test design with control group design, with a sample size of 30 older adults, sampling technique using random sampling carried out for one week consuming one day three times. Results: The paired t-test showed a p-value of 0.0001, indicating a significant difference between the average uric acid levels before and after Annona muricata leaf extract administration. Soursop leaves contain flavonoid and tannin compounds, where flavonoids can inhibit the production of the enzyme xanthine oxidase. By inhibiting this enzyme, the process of forming hypoxanthine into xanthine is also hampered, thereby reducing excess uric acid production. Apart from reducing uric acid levels in the blood, soursop leaves can also reduce pain in people with gouty arthritis thanks to the tannin, resin and Agostini content, which can relieve pain and reduce swelling and pain. Conclusions: Administration of A. Muricata leaf extract has proven effective in reducing uric acid levels in older adults with hyperuricemia
Efektivitas Ekstrak Daun Annona Muricata Terhadap Penurunan Kolesterol Total Pada Lansia Dengan Hiperkolesterolemia Di Panti Werdha Mojopahit Mojokerto Muhammad Al Amin; Ainun Najib; Ali Syahbana
PROFESSIONAL HEALTH JOURNAL Vol. 5 No. 1 (2023): Desember
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v5i1.405

Abstract

The elderly experience a decrease in function, especially in the function of blood circulation. Blood circulation diseases and hormonal metabolism disorders experienced by the elderly include hypercholesterolemia. Hypercholesterolemia is a disorder of fat metabolism that triggers an increase in total blood cholesterol levels, namely> 200 mg/dl. The study aimed to determine the effectiveness of A. muricata leaf extract in decreasing total cholesterol levels in the elderly with hypercholesterolemia. Quantitative research method, using a quasi-experimental type with a group pretest-posttest design, with a sample size of 20 elderly. The sampling technique used purposive sampling, was carried out for a week consuming three times a day. The paired t-test showed a value of 8.73 and a p-value of 0.001. This study's results indicated a significant difference between the average cholesterol levels in the pre-test and post-test administration of Annona Muricata leaf extract. Compounds contained in soursop leaves, namely flavonoids, by reducing the activity of HMG-koa reductase (enzyme β-Hydroxy β-methylglutaryl-CoA) can reduce the activity of ACAT (enzyme acyl-Coa cholesterol acyltransferase), and reduce the absorption activity of cholesterol in the liver. Digestive tract. Saponin compounds in soursop leave lower cholesterol by binding to cholesterol in the intestinal lumen, thereby preventing the reabsorption of cholesterol. Saponins can bind with bile acids, which in turn will reduce the enterohepatic circulation of bile acids and cause an increase in the process of excretion of cholesterol.
Reducing blood uric acid levels after drinking Annona muricata linn (soursop leaf) extract: study in elderly with hyperuricemia Muhammad Al Amin; Ainun Najib; Ali Syahbana; Efina Amanda
PROFESSIONAL HEALTH JOURNAL Vol. 6 No. 1 (2024): December
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v6i1.788

Abstract

Introduction: Gout is a degenerative disease that often attacks joints, especially in older adults. This disease is caused by the buildup of uric acid crystals in the joints, which causes inflammation and severe pain. One of the main indications that someone suffers from gout is if the results of measuring the uric acid level in the blood are more than 7.0 (mg/dL), whereas in women, it is more than 5.7 mg/dL. Objectives: Research to determine the effectiveness of A. Muricata leaf extract in reducing uric acid levels in older adults with hyperuricemia. Methods: Quantitative research, using a quasi-experimental type with Pre-test, Post-test design with control group design, with a sample size of 30 older adults, sampling technique using random sampling carried out for one week consuming one day three times. Results: The paired t-test showed a p-value of 0.0001, indicating a significant difference between the average uric acid levels before and after Annona muricata leaf extract administration. Soursop leaves contain flavonoid and tannin compounds, where flavonoids can inhibit the production of the enzyme xanthine oxidase. By inhibiting this enzyme, the process of forming hypoxanthine into xanthine is also hampered, thereby reducing excess uric acid production. Apart from reducing uric acid levels in the blood, soursop leaves can also reduce pain in people with gouty arthritis thanks to the tannin, resin and Agostini content, which can relieve pain and reduce swelling and pain. Conclusions: Administration of A. Muricata leaf extract has proven effective in reducing uric acid levels in older adults with hyperuricemia
Co-Authors A. Syafi' AS. Abdillah Azzihab Abdul Jalil Abim Bhakti Ach. Raziqin Admiral Musa Julius Agatha, Melinda Yulia Ai Nurjanah Aini Sih Permana, Embun Al Amin, Muhammad al-Chudri, M. Ridho Maulana Al-Huda, Mohammad Aqil Ali Syahbana Amanatuz Zuhriyah Amanda, Efina Amin Amrullah, Faruq Aminah Nur Kauthar Binti Zawawi Ana, Selvia Roos Andi Ahmad Aminullah Andi Yudianto, Andi Andri Wijaya, Rizqi Ani Qomariyah Anwar, Thoful Arifudin, Moch. Safri Avanda, Pretty Aura Natasya Bagaskara, Bernardus Firman Budiawan, Ahmad Nafis Bunga Ratulian, Bestia David Ndaru Aji Pramudya Diah Sudiarti Dini Nuraini, Enok Dyah Ayu Suryaningrum Efina Amanda Fadillah, M. Amirul Faizah, Mamluatul Fathur Rohman, Fathur Fitriani, Hilna FUADI, ILHAM Gayuh Prasetyo Budi Hadromi - Hani Syarifah Hanifa, Nur Lailatul Hanum, Salsabila Hartono, R.Yudi Hayatul Khairul Rahmat Hayya, Adieba Warda Hendro Pratikno Herin Mawarti Huda, Aniq Nauval I Dewa Ketut Kerta Widana Ifad Fadlurrahman Ilham Kusumo, Januar Karimullah, Suud Sarim Khairunnisa Adri Khotimah, Suci Nurul Kurnia Sandie , Ichsan Latifah, Lafifatul Liam, Liam Linda Uril Khofifah Lintang Kumala, Shilla Lostari, Aini M, Muhammad Shohibu Mashudi Mashudi Maula Nasrifah Mega Puspitasari, Herlina Mega, Brunika Miftahul Ulum Mirza Andrian Syah Misti Hariasih Moh. Ali Hofi Muamar Sholih , Arrasyid Mubarok, Yusuf Mufaridah, Hanik Muhammad Al Amin Muhammad Izamul Maruf Al Fahmi Muhammad Zulfikar Asumta Muharom, Mohammad Syahrul Mushofi, Rfiul Muslim, Imam Bukhori Muzadi, Ahmad Rafi Nasirun, Muhammad Khoirun Novitasari, Nurul Nrangwesthi Widyaningrum Nur Utami, Indriya Nurul Qomariyah, Ira Oetami Dwi Hajoeningtijas Patekun, Patekun Poetro, Bagus Satrio Waliyo Prika Fatikasari Qomariyah, Ani Raditya Damaris, Andreas Rahmawati, Rahmawati Rajab, Alfian Abdul Ramadhan, Jundullah Faqihuddin Riani, Novi Indah Risbon Sianturi Rizkia Mutiara Ramadhani Ronaltama Mabrur, Edwin Rustam Effendi Salma Fadhilah, Nur Setyawan, Ricky Andris Sri Mulyono Sudarti Sudarti Sugiono, Didik Sugiyono Sugiyono Sumriyah Sumriyah Sunarko, Mas Supardi Supardi Sutedja, Ade Armada Tego Suroso Teguh Pribadi Tyas Wahyuni, Leny Eka Ulin Nuha, Ulin Umar Umar Viera Salsabiela Rachman Wahyudi Wahyudi wahyuni wahyuni Wati, Tita Pertama Wiranti, Dwiana Wulandari, Devita Endah Wulandari, Eka Yunita Yani Dahliani Yasin Efendi Yudhi Eka Hanafi Zain, Muhammad Yasir