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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Berkala Ilmu Kesehatan Kulit dan Kelamin Indonesian Journal of Tropical and Infectious Disease ISM (Intisari Sains Medis) : Jurnal Kedokteran JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal EduHealth Molucca Medica

Linda Astari, Linda

Departemen/Staf Medik Fungsional Ilmu Kesehatan Kulit Dan Kelamin Fakultas Kedokteran Universitas Airlangga/Rumah Sakit Umum Daerah Dr. Soetomo Surabaya

Author-ID : 3287335

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Clinical and Cure Profile of Tinea Capitis Patients Noviannisa, Farah Ayu; Astari, Linda; Alimsardjono, Lindawati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.86-91

Background: Tinea capitis (TC) is a superficial mycoses infection of hair follicles and hair shaft caused by dermatophytes of the genus Trichophyton and Microsporum. Tinea capitis can cause hair loss and scales with varying degrees of inflammatory response. The incidence varies depending on geographical location and factors that affect the incidence rate. It is important to know the incidence also the clinical and cure profile of tinea capitis to provide benefits in the prevention, diagnosis, and treatment. Purpose: To evaluate the clinical and cure profile of TC patients at the Dermatology and Venereology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya from January 2019 to January 2020. Methods: A retrospective descriptive study based on medical records with a total sampling technique. Result: Of the 10 TC patients, who were the research subjects, TC predominantly affected males and at 5–11 years age group. The highest risk factor was a history of contact with cats. Scales were the most common clinical feature. Microsporum canis was the most common causative species, ectothrix arthrospores was revealed during the direct microscopic examination, Wood lamp's fluorescence was mostly yellow-green, and cigarette-shaped hair was the most common dermoscopic finding. Eighty percent of subjects were diagnosed with gray patch type. Conclusion: The diagnosis of TC was established based on the patient's history, clinical examination, and supporting examination.

Pattern of Candida Species Isolated from Patient with Vulvovaginal Candidiasis in Pregnancy Purnamasari, Indah; Ervianti, Evy; Damayanti, Damayanti; Budi Prasetyo; Astari, Linda; Pepy D. Endraswari; Listiawan, M. Yulianto; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.178-183

Background: Vulvovaginal candidiasis (VVC) is one of the most prevalent genital tract diseases in women. The identification of the isolated Candida species is critical for guiding empirical antifungal therapy. Purpose: To determine the Candida species that cause vulvovaginal candidiasis in pregnancy at the Obstetrics and Gynecology Outpatient Clinic, Dr. Soetomo General Academic Hospital, thus providing scientific and therapeutic benefits. Methods: Pregnant woman receiving antenatal care (ANC) at Dr. Soetomo General Academic Hospital Obstetric and Gynecology Outpatient Clinic. Subjects were enrolled in a cross-sectional study during 3 months between March and May 2021. Vaginal swab samples were taken from subjects after informed consent. A specific color change in CHROMagar cultures and VITEK 2 compact were used to identify Candida species. Result: During the study period, 15 pregnant patients were diagnosed with VVC. The majority of the women in the study were pregnant women of sexually active age who complained of a whitish body and genital irritation. There were 18 candida isolates from CHROMagar cultures, with C. non albicans (61.1%) predominating over C. albicans (38.3%). With details, non albicans were C. glabrata (54.4%), C. dubliniensis (36.3%), and C. parapsilosis (18.1%). Conclusion: This study revealed a high prevalence of Candida non-albicans species causing VVC. Culture investigation and identification of Candida are critical to avoid diminished susceptibility to antifungal treatments and recurrence.

Evaluation of Histopathology Findings of Clinically Confirmed Psoriasis Vulgaris Sawitri; Fadila, Arisia; M. Yulianto Listiawan; Priangga Adi Wiratama; Dwi Murtiastutik; Evy Ervianti; Linda Astari; Damayanti; Diah Mira Indramaya; Afif Nurul Hidayati; Medhi Denisa Alinda
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.21-26

Background: Psoriasis vulgaris can be diagnosed clinically. A biopsy is usually used to confirm non-classic cases. The findings of the histopathology feature are not usually present, thus clinical relevance is needed to confirm the diagnosis. Purpose: To describe the histopathology findings from tissue samples of histopathologically confirmed psoriasis vulgaris reported in the Department of Pathology and Anatomy of Dr. Soetomo General Hospital. Methods: A descriptive-retrospective study of pathology-ascertained tissue samples of histopathologically confirmed psoriasis vulgaris was reported in the Department of Pathology and Anatomy from patients who were also previously diagnosed clinically with psoriasis vulgaris in the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital over a period of 2 years. Morphological parameters were observed after histopathology sections were stained with hematoxylin and eosin. Result: Thirty-three tissue samples were examined. Parakeratosis (86%) and hypogranulosis (70.3%) were the most observed findings. Club-shaped rete ridges, suprapapillary plate thinning, and spongiform pustules of Kogoj were the least observed findings (each by 2.7%). Three tissue samples (8.1%) showed only parakeratosis. Only 1 tissue sample (2.7%) showed 4 features (absence of the granular layer, parakeratosis, microabscess of Munro, and spongiform pustules of Kogoj). No tissue sample showed every histopathology finding of psoriasis vulgaris. Conclusion: All of the histopathology features of psoriasis vulgaris are rarely found in one tissue section. Albeit histopathology is believed to be the gold standard diagnosis of psoriasis vulgaris, relevance with clinical findings is still mandatory to support the diagnosis.

The Effects of Hormonal Factor on the Degree of Acne Vulgaris Severity Alarik L., Albertus; Indiastuti, Danti Nur; Astari, Linda; Setyaningrum, Trisniartami
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 2 (2023): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.2.2023.126-129

Background: Acne vulgaris is a disease in the form of chronic inflammation of the pilosebaceous follicles with multifactorial causes. Acne vulgaris is a very common skin disease with a prevalence of 85% in the age range of 18-25 years. There are aggravating factors that can exacerbate acne vulgaris, including hormonal factors. However, the study about how strong the effects of hormonal factors and on acne severity is really limited. Purpose: The objective of this research is to determine how strong hormonal factors contribute on the severity of acne vulgaris. Methods: This was a cross-sectional retrospective study using secondary data obtained from 199 patients at the Dermatology and Venereology Outpatient Unit of RSUD Dr. Soetomo from January- December 2019. The data were analyzed using SPSS with regression analysis.Result: Hormonal factors significantly influenced the degree of acne vulgaris severity (P-value=0.030). Based on the logistic regression model, it can be found that hormonal factors influence the degree of acne vulgaris by 70% Conclusion: The effect of hormonal factors on the severity of acne vulgaris is 70%.

Concordance Test Between Dermoscopic and Histopathological Parameteres in Basal Cell Carcinoma Hartanto, Felix; Kusumaputra, Bagus Haryo; Sari, Maylita; Citrashanty, Irmadita; Mappamasing, Hasnikmah; Astari, Linda; Sandhika, Willy; Hidayati, Afif Nurul; Prakoeswa, Cita Rosita Sigit; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.6-11

Background: Basal cell carcinoma (BCC) is the most common skin cancer and can cause local tissue damage. BCC can occur in all populations, regardless of skin color. Dermoscopy has compatibility with histopathology in determining the benign or malignant nature of a lesion. Dermoscopy can improve the diagnostic accuracy of BCC by >90%, with 7 parameters that can be found: arborizing vessels, blue-gray ovoid nests, blue-gray dots/globules, maple leaf-like areas, spoke-wheel areas, ulceration, and hiny white areas. Purpose: To assess the compatibility of each dermoscopy parameter with its corresponding histopathological parameters. Methods: Observational analytic study with a cross-sectional approach was performed. Dermoscopy parameters were obtained by reassessing all photographs, while histopathological parameters were obtained from pre-existing slide reviews. Cohen's Kappa test was performed to analyze both variables. Result: A Total of 26 samples met the inclusion criteria. Most BCCs were found in female sex (65.4%), age >50 years (80.8%), and facial location (88.5%). Cohen's Kappa test was significant in 2 out of 7 dermoscopy parameters: "blue-gray ovoid nests" (p = 0.0019; r = 0.458) and "spoke wheel areas" (p = 0.037; r = 0.371). The "shiny white areas” parameter could not be analyzed because there was no negative variation in the examination. The possibility of false positives and negatives could not be ruled out. Conclusion: Significance between the two variables is found in 28.6% of the 7 parameters analyzed...

Clinical Manifestations and Distribution of Treatment for Pyoderma at a Tertiary Hospital in Surabaya, Indonesia Auliya, Arsya; Astari, Linda; Puspitasari, Dwiyanti; Alinda, Medhi Denisa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.12-19

Background: Pyoderma is a skin disease caused by infection with Gram-positive bacteria. In Indonesia, this disease has a high prevalence due to inadequate sanitation, climate condition, humidity, and high population density. Patients with pyoderma present in diverse range of symptoms, in the form of clinical manifestation or systemic symptoms. Inadequate management of pyoderma can lead to an escalation in morbidity rates. Therefore, it is important to conducting comprehensive research about clinical profile of pyoderma patients. Purpose: To describe the profile of pyoderma patients in Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Acdemic Hospital Surabaya in January 2016 to December 2018. Methods: This study is a retrospective descriptive analysis using secondary data derived from medical records at Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital Surabaya. Result: The analysis of pyoderma patient at Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital Surabaya in January 2016 to December 2018 reveals a total of 407 patients, predominantly male and the most age category were toddlers. Most clinical diagnosis were furuncles and carbuncles. Among the clinical manifestations, macula was the most frequent primary skin lesion, while erosion predominated among secondary lesions. The most commonly administered therapies were systemic and topical antibiotics. Conclusion: In the period from January 2016 to December 2018, clinical manifestations of pyoderma patients at the Dermatology and Venereology Outpatient Unit of Dr. Soeto...

Education and Workshop Improve Healthcare Workers' Knowledge of Laboratory Examination for the Diagnosis of Superficial Dermatomycosis Ervianti, Evy; Astari, Linda; Rahmadewi; Setyaningrum, Trisniartami; Mappamasing, Hasnikmah; Anggraeni, Sylvia; Widia, Yuri; Ngesti Kumalasari, Diah; Axelia, Presstisa Gifta; Hadiwidjaja, Farsha Naufal; Sunarto, Olivia Awwalin; Kathrin Kezia Henry; Sulaksanaswastho Suyoso; Puspowati, Erindah
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.187-192

Background: Superficial dermatomycosis is one of the most prevalent skin diseases worldwide. The diagnosis of superficial dermatomycosis is established clinically, and supported by several examinations, such as microscopic examination, fungal culture, and Wood's lamp examination for certain species. Purpose: This study is to evaluate the improvement of the knowledge of general practitioners and medical analysts after education and workshop. Methods: This cross-sectional observational study involved 70 subjects, consisting of 35 general practitioners and 35 medical analysts from 35 public health centers in Bojonegoro who were willing to participate in this study. The level of knowledge was assessed before and after the health education on laboratory examination for the diagnosis of superficial dermatomycosis. Result: There was a significant difference in mean scores between the pre-test and post-test after health education (p = <0.001). The mean knowledge score of the pre-test before intervention among general practitioners was 36.57 ± 19.088, which increased to 68.00 ± 13.240, and the mean knowledge score before intervention among analysts was 27.14 ± 13.842, which increased to 62.00 ± 12.078 after health education intervention. Conclusion: Following health education, there was an improvement in the healthcare workers's knowledge of laboratory examinations for the diagnosis of superficial dermatomycosis

Mycobacterium leprae Survival Inside Acanthamoeba sp. Isolated from Water Source in Leprosy Endemic Area, Indonesia: Mycobacterium leprae Survival Inside Acanthamoeba sp. Wahyuni, Ratna; Astari, Linda; Iswahyudi, Iswahyudi; Paling, Sepling; Adriaty, Dinar; Kurniawati, Siti; Aulia, Syifa; Rahmatari, Bandaru; Prakoeswa, Cita Rosita; Agusni, Indropo; Izumi, Shinzo
Journal of Tropical Life Science Vol. 14 No. 2 (2024)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.02.07

Mycobacterium leprae is an acid-fast bacterium that causes leprosy diseases, which remains a problem worldwide. Even though leprosy prevalence in the world has decreased significantly, many endemic pocket areas continue reporting new cases and harbor M. leprae in the environment, including water and soil. The presence of obligate intracellular bacteria-M. leprae in the environment raises a question on how it survives. Free-living amoeba has been proposed as its reservoir host in the environment. The study was conducted to give evidence that M. leprae can survive inside free-living amoeba isolated from water sources of leprosy endemic areas. M. leprae from leprosy patients was cultured together with Acanthamoeba sp. isolated from the water source of the leprosy endemic area. Viability and duplication of M. leprae inside amoeba then observed at day 14 and 28 using reverse transcriptase PCR and qPCR. The results showed that M. leprae survived inside the amoeba until day 28, but no bacterial replication was observed. The study reveals in vitro evidence of viable M. leprae inside free-living amoeba of leprosy endemic area environment.

Chemical Peeling in Skin-Aging Patients: A Retrospective Study Susanto, Ester Chateline; Setyaningrum, Trisniartami; Arifa Mustika; Astari, Linda
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.6-14

Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and theextracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involvesskin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling atthe Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January throughDecember 2019. Methods: The data were obtained from patients' medical records through a total sampling technique, whichconsisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55(35.1%), female (100%), and private employees (32.4%). In history taking, patients' main complaint is dull skin (94.6%), withthe risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in allpatients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). Themajority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeuticoutcomes.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.02.07

Co-Authors Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Alarik L., Albertus Alimsardjono, Lindawati Alpha Fardah Athiyyah Alya Nuha Andini Amanda Gracia Manuputty Anang Endaryanto Anggraeni Noviandini Anggraeni, Sylvia Ardhiah Iswanda Putri Arifa Mustika Astindari Astindari Astindari Astindari, Astindari Aulia, Syifa Auliya, Arsya Axelia, Presstisa Gifta Bagus Bagus Bagus Haryo Kusumaputra, Bagus Haryo Bramantono Bramantono, Bramantono Brigita Ika Rosdiana Budi Prasetyo Budi Utomo Budi Utomo Budiono Budiono Chesia Christiani Liuwan Christina Avanti Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti David Sontani Perdanakusuma Densy Violina Harnanti Desiana Widityaning Sari Dewi Puspitorini Dhyah Aksarani Handamari Diah Mira Indramaya DINAR ADRIATY Dwi Murtiastutik Dwi Ratna Adisty Dwiyanti Puspitasari, Dwiyanti Dyah Ratri Anggarini Dyah Ratri Anggarini, Dyah Ratri Endang Wahyu Fitriani Erwin Astha Triyono Esti Hendradi Eva Lydiawati Evy Ervianti Fadila, Arisia Farhat Surya Ningrat Hadiwidjaja, Farsha Naufal Hari Sukanto, Hari Harningtyas, Citra Dwi Hartanto, Felix I Gusti Ayu Agung Elis Indira I Gusti Nyoman Darmaputra Indah Purnamasari Indiastuti, Danti Nur INDROPO AGUSNI Ingrid Suryanti Suryono Irmadita Citrashanty Irmadita Citrashanty, Irmadita Iskandar Zulkarnain Iskandar Zulkarnain ISWAHYUDI ISWAHYUDI Kathrin Kezia Henry Kinanti Prabawaningrum Kurniati Kurniati M. Yulianto Listiawan ManikRetno Wahyunitisari Mappamasing, Hasnikmah Maylita Sari Maylita Sari, Maylita Medhi Denisa Medhi Denisa Alinda, Medhi Denisa Meita Ardini Pratamasari, Meita Ardini Merilyne Merilyne Musofa Rusli Ngesti Kumalasari, Diah Noviannisa, Farah Ayu Nyoman Suryawati Pepy D. Endraswari Pepy Dwi Endraswari, Pepy Dwi Prakoeswa, Cita Rosita Priangga Adi Wiratama Puspowati, Erindah Putri Hendria Wardhani Putri, Melati Adinda Rahmadewi Rahmadewi Rahmadewi Rahmatari, Bandaru RATNA WAHYUNI Regitta Indira Agusni Renata Prameswari Retha Retha Ridha Ramadina Widiatma Riyana Noor Oktaviyanti Sawitri Sawitri Sawitri Selvia Yuliani Dwi Ratih Sanggarwati Sepling Paling Sheilaadji, Maria Ulfa Shinta Dewi Rahmadhani Soetojo SHINZO IZUMI Siti Kurniawati Sulaksanaswastho Suyoso Sunarso Suyoso Sunarso Suyoso Sunarso Suyoso Sunarto, Olivia Awwalin Susanto, Ester Chateline Tjokorde Istri Nyndia Vaniari Trisniartami Setyaningrum Vidyani Adiningtyas Widyantari, Septiana Willy Sandhika Yuri Widia, Yuri Yuri Widya Zahruddin Ahmad

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