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All Journal Indonesian Journal of Pharmaceutical Science and Technology Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Acta Pharmaceutica Indonesia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Fitofarmaka Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) FITOFARMAKA: Jurnal Ilmiah Farmasi Journal of Pharmaceutical and Medicinal Sciences JFIOnline JURNAL FARMASI GALENIKA Jurnal Mandala Pharmacon Indonesia Jurnal Ilmiah Farmasi Farmasyifa Narra J Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Kefarmasian Borneo Journal of Pharmacy Jurnal Farmasi Galenika Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Nursamsiar Nursamsiar
Sekolah Tinggi Ilmu Farmasi Makassar, Perintis Kemerdekaan Street Km 13,7 Daya, Makassar-Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Edukasi Pencegahan Penyakit Skabies Melalui Peer Educator Di Sekolah Enterpreneur Tahfidz Kekasih Al-Aqsha, Gowa, Sulawesi Selatan Muslimin, Lukman; Marwati, Marwati; Mus, Suwahyuni; Rosyid, Sujud Z; Irwana, Rina; Djamaluddin, Suci F; Khairi, Nur; Indrisari, Maulita; Nursamsiar, Nursamsiar; Megawati, Megawati; Imrawati, Imrawati; Nur, Syamsu; Sami, Fitriyanti; Amin, Astuti; Paluseri, Andi
Jurnal Pengabdian Kefarmasian Vol 4, No 2 (2023): JURNAL PENGABDIAN KEFARMASIAN
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jpk.v4i2.3421

Abstract

Scabies Prevention Through Peer Educators At The Entrepreneur School Of Tahfidz Kekasih Al-Aqsha, Gowa, South SulawesiBased on a survey that was carried out, it was found that there were incidents of head lice and scabies infections at the Tahfidz Kekasih Al-Aqsa Entrepreneurial School, in Pattallassang, Kab. Gowa, South Sulawesi. This shows that the student's knowledge of this disease is still low. So it is necessary to carry out outreach to increase students' knowledge of the dangers of scabies and its treatment. 45 students and 5 teachers attended this counseling. The methods used in this service are lecture, question and answer, and scabies examination. The presentation of material about scabies was carried out using PowerPoint media, after which the material continued with a question-and-answer session. At the end of the activity, a health examination was carried out to identify and provide treatment to students and teachers who suffered from scabies. The results of the counseling showed that 2 students were suffering from scabies. The counseling was considered successful because the students answered all the questions (100%).Keywords: Counseling, Peer Education, Scabies Berdasarkan survei yang telah dilakukan ditemukan adanya kejadian infeksi kutu rambut dan skabies (kudis) di Sekolah Enterpreneur Tahfidz Kekasih Al-Aqsha, di Pattallassang, Kab. Gowa, Sulawesi Selatan. Hal ini menunjukkan masih rendahnya pengetahuan para santri terhadap penyakit tersebut. Maka perlu dilakukan sosialisasi untuk meningkatkan pengetahuan santri terhadap bahaya penyakit skabies serta pengobatannya. Penyuluhan ini diikuti oleh 45 orang santri dan 5 orang guru. Metode yang digunakan dalam pengabdian ini adalah metode ceramah, tanya jawab, dan pemeriksaan skabies. Pemaparan materi tentang skabies dilakukan menggunakan media PowerPoint, setelah pemaparan materi dilanjutkan dengan sesi tanya jawab. Di akhir kegiatan, dilakukan pemeriksaan kesehatan untuk mengetahui dan memberikan pengobatan kepada santri maupun guru yang menderita skabies. Hasil penyuluhan menunjukkan bahwa ada 2 orang santri yang menderita skabies. Penyuluhan dinilai berhasil karena semua pertanyaan yang diberikan berhasil dijawab oleh santri (100%).Kata kunci : Penyuluhan, Peer Education, Skabies
AKTIVITAS ANTIOKSIDAN EKSTRAK ETIL ASETAT BERBAGAI BAGIAN TANAMAN KESAMBI (Schleichera oleosa L.) DENGAN METODE DPPH Nursamsiar, Nursamsiar; Khairuddin, Khairuddin; Marwati, Marwati; Nur, Syamsu
Indonesian Journal of Pharmaceutical Science and Technology Vol 11, No 1 (2024)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v11i1.38871

Abstract

Kesambi (Schleichera oleosa) merupakan salah tanaman asli Indonesia yang berpotensi sebagai obat dan memiliki senyawa aktif yang berpotensi sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui potensi berbagai bagian tanaman sebagai antioksidan dengan metode DPPH. Simplisia diekstraksi dengan metode maserasi menggunakan pelarut etil astetat. Identifikasi golongan senyawa dilakukan dengan skrining fitokimia menggunakan reagen kimia sedangkan pengujian aktivitas antioksidan dilakukan dengan metode peredaman radikal DPPH menggunakan spektrofotometer pada panjang gelombang 515 nm. Hasil skrining fitokimia menunjukkan bahwa semua ekstrak etil asetat dari berbagai bagian tanaman mengandung senyawa flavonoid, fenolik dan tannin. Pengujian aktivitas menunjukkan ekstrak etil asetat daun kesambi memiliki aktivitas antioksidan paling baik dengan nilai IC50 5,4952 μg/mL, dibandingkan dengan kulit batang (14,3621 μg/mL), akar (43,4159 μg/mL), kulit buah (159,8782 μg/mL) dan daging buah (167,2912 μg/mL). Ekstrak etil asetat berbagai bagian tanaman kesambi memiliki aktivitas antioksidan dengan urutan paling baik yaitu daun, kulit batang, akar, kulit buah, dan daging buah. Adanya profil bioaktivitas tersebut dapat memberikan informasi tambahan terhadap kekuatan atioksidan pada berbagai bagian tanaman kesambi yang belum dilaporkan pada penelitian sebelumnya sehingga dapat dikembangkan untuk penelitian lebih lanjut.
PENENTUAN KADAR AMILOSA DARI UMBI TALAS SAFIRA (Colocasia esculenta Schoot var. antiquorum) MENGGUNAKAN METODE SPEKTOFOTOMETRI UV-Vis nursamsiar nursamsiar; Kristina Pasongli; Hamdayani L. A.; Aiyi Asnawi; Fauzan Zein Muttaqin
JURNAL FARMASI GALENIKA Vol 3 No 2 (2016): Jurnal Farmasi Galenika Volume 3 No. 2, 2016
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kadar amilosa yang terdapat pada pati dapat mempengaruhi sifat fisikokimia dari pati. Pati dengan kadar amilosa yang relatif cukup banyak dapat dimanfaatkan untuk formulasi obat. Pati memiliki rasio amilosa dan amilopektin yang beragam yang sangat penting sebagai parameter dalam pemilihan sumber pati yang akan digunakan dalam industri. Sehingga pengembangan metode analisis untuk penentuan rasio ini merupakan hal yang sangat menantang. Tujuan penelitian ini untuk mengetahui kadar amilosa dari umbi talas safira dengan menggunakan metode spektrofotometri UV-Vis. Proses ekstraksi pati dilakukan dengan proses pengendapan. Amilosa dapat dipisahkan dari pati berdasarkan perbedaan sifat kelarutannya dalam air panas. Rentang kurva kalibrasi yang diperoleh adalah 20-70 bpj dengan koefisien korelasi (r) = 0,99968. Metode yang digunakan mempunyai batas deteksi (LOD) adalaj 1,2202 bpj, denganbatas kuantitasi (LOQ) 4,0673 bpj dan koefisien variasi fungsi regresi 0,9038%. Hasil analisis terhadap sampel hasil isolasi dari pati talas safira dan ekstrak pati talas safira diperoleh kadar amilosa berturut-turut adalah sebesar 90,8% b/b dan 96,95% b/b. Kadar amilosa pada sampel amilosa hasil isolasi dari pati talas safira lebih rendah (90,8% b/b) dibandingkan dengan yang terkandung dalam ekstrak pati talas safira (96,97% b/b).
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KEDONDONG HUTAN (Spondias pinnata (L.F.) Kurz.) DENGAN BERBAGAI METODE UJI Suhaimi Azizah; Nursamsiar Nursamsiar; Syamsu Nur
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.227

Abstract

The leaf of kedondong hutan (Spondias pinnata (L.F.) Kurz.) Contain of flavonoid compound, which capable as antioxidants that function for preventing free radicals. The purpose of this study was to determine the antioxidant activity profile of ethanol extract of kedondong hutan leaf with DPPH, ABTS radical and iron reduction methode (FRAP). This study used experimental research with stages of sample collection, plant determination, simplicia preparation, maceration with 70% ethanol, phytochemical screening and antioxidant activity assay with UV-Vis spectrophotometry. The results obtained from the ethanol extract of kedondong hutan leaves had antioxidant activity on DPPH and ABTS with IC50 of 32.83 ppm and 45.84 ppm respectively. In FRAP method kedondong hutan leaves had antioxidant activity which is equivalent to quarcetin of 2936.7 µmol QR /g sample. Ethanol extract of kedondong hutan leaves has very strong antioxidant power against DPPH, ABTS radical and iron reduction.
Screening Bioactivity of Kersen Fruits (Muntingia calabura L.) as a Sunscreens Candidate: Skrining Bioaktivitas dari Buah Kersen (Muntingia calabura L.) sebagai Kandidat Bahan Tabir Surya Nur, Syamsu; Nursamsiar, Nursamsiar; Aswad, Muhammad; Tumigolung, Aprilia Ester Eunike; Risfah Yulianti; Burhan, Asril
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15257

Abstract

Kersen (Muntingia calabura L) fruits have the potential to be used as an active ingredient in sunscreens because of phenolic and flavonoid content that can absorb UV rays. This study aims to determine the percentage of erythema/pigmentation transmission and SPF value as parameters for sunscreen activity. Kersen fruits were extracted by maceration using 96% ethanol. The ethanol extract of Kersen Fruits was also fractionated to separate the components of the active compounds based on the polarity level using n-hexane, ethyl acetate, and ethanol as solvents. The test was carried out using the in vitro method by measuring the ability of the material to absorb ultraviolet light at a wavelength of 292.5-372.5 nm. This research was conducted at concentrations of 100, 200, 400, 600, and 800 µg/mL for ethanol, lyophilisate, n-hexane, and ethanol fractions, while the ethyl acetate fraction concentrations are 50, 100, 150, 200, 250 µg/mL. The results showed the best value at the ethyl acetate fraction concentration of 250 µg/mL with % Te of 5.28 and % Tp of 28.65 and the SPF value of 16.54. Based on the % Te and Tp, the ethyl acetate fraction exhibited protection against erythema and pigmentation with the category of extra protection and based on the SPF value with the category of ultra protection.
Phytochemical profiling and enzyme inhibitory activity of Sterculia populifolia DC stem bark extract and fractions against elastase and tyrosinase Khairi, Nur; Nursamsiar, Nursamsiar; Utami, Novi F.; Marwati, Marwati; Nur, Syamsu; Indrisari, Maulita; Kursia, Sukriani
Narra J Vol. 5 No. 3 (2025): December 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i3.1778

Abstract

The demand for natural ingredients in cosmetic and medical applications is steadily increasing, particularly for anti-aging and skin-lightening products. Sterculia populifolia DC, a member of the Sterculia genus, is known to contain diverse bioactive compounds such as flavonoids, phenolics, and terpenoids, which may offer pharmacological benefits. The aim of this study was to evaluate the anti-aging potential of S. populifolia stem bark extract and its solvent-partitioned fractions through enzyme inhibition assays coupled with phytochemical profiling. The stem bark was extracted using 96% ethanol via maceration, followed by sequential liquid-liquid partitioning with n-hexane, ethyl acetate, n-butanol, and water. Phytochemical constituents were characterized using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The inhibitory activities of the extract and fractions against tyrosinase and elastase enzymes were evaluated using spectrophotometric assays, with kojic acid and quercetin as positive controls, respectively. IC₅₀ values were calculated to quantify enzyme inhibition potency. LC-MS/MS analysis revealed key bioactive compounds, including 4-[(E)-(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol, isofraxidin, and (22E)-ergosta-4,6,8(14),22-tetraen-3-one. Among the tested samples, the ethanol extract exhibited the most potent activity, with an IC₅₀ of 93.35 µg/mL for elastase inhibition and 133.15 µg/mL for tyrosinase inhibition—classified as strong and moderate activity, respectively. Collectively, these findings demonstrate that S. populifolia stem bark extract possesses promising anti-aging and depigmenting properties, supporting its potential development as a natural bioactive ingredient in cosmetic and skincare formulations.
Effect of Solvent Polarity on Antioxidant and Antidiabetic Activity of Kesambi Leaf Extract (Schleichera oleosa L.) Nursamsiar, Nursamsiar; Marwati, Marwati; Sami, Fitriyanti J.; Nur, Syamsu; Kasmawati, Henny; Asnawi, Aiyi
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.9439

Abstract

Kesambi (Schleichera Oleosa (L.) is one of the beneficial plants in Indonesia which contains fenolic and flavonoids that exhibit antioxidant properties. The presence of antioxidants in plants could be associated with antidiabetic activity of these plants. This research was conducted to determine the antioxidant and antidiabetic activities of n-hexane, ethyl acetate, acetone and methanol extracts from Kesambi leaves. Extraction was carried out by the ultrasonic assisted extraction (UAE) method. The antioxidant activity was determined quantitatively by DPPH and ABTS method, while the antidiabetic activity was evaluated by using α-glukosidase inhibition method. The IC50 values from the determination of antioxidant and antidiabetic activities were obtained by using Microplate reader at the maximum wavelength. Results of the antioxidant determination DPPH method showed that IC50 values of n-hexane, ethyl acetate, acetone and methanol extracts were 414.1993; 57.7862; 6.33 dan 13.4558 µg/mL, respectively. And for ABTS method showed 162.679; 22.6684; 10.7975; dan 146.869 µg/mL. This indicates the acetone and methanol extracts give the best results in antioxidant activity. Meanwhile, IC50 values of in vitro antidiabetic activity of n-hexane, ethyl acetate, acetone and methanol extracts were 99.3235; 272.8723; 1.6799; dan 24.4653 µg/mL, respectively. Acetone and methanol extracts of kesambi leaf give the best results in antidiabetic activity.
Co-Authors A Syarifah Hamida Assagaf A., Hamdayani L. Achnis Akbar Jum Adrianti Palino Aisyah Aisyah Aisyah F, Aisyah Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Akbar Awaluddin Akrom, Akrom Alfad Fadri Alfat Fadri Alfat Fadri Alfat Fadri Alprida Tandi Toding Andi Nur Aisyah Andi puanguce Paluseri Anugerah Sukmayanti Asril Burhan Astuti Amin Azizah, Suhaimi Besse Hardianti Besse Hardianti Burhan, Asril Christa A. M. Suares Dayan El-Roy Matitawaer Djamaluddin, Suci F Ellin Febrina Erli Berlianti Fatima Fatima Fauzan Zein Muttaqin Fhahri Mubarak Fitriyanti Jumaetri Sami Fitriyanti Jumaetri Sami Fitriyanti Jumaetri Sami Fitriyanti Sami H.Tjahjono, Daryono H.Tjahjono, Daryono Hamdayani L. A. Imrawati Imrawati Indradewa, Rhian Irwana, Rina Ivan Andriansyah Julianri Sari Lebang Julianri Sari Lebang, Julianri Sari Jumarni Jumarni Kasmawati, Henny Khaeri, Nur Khaeri, Nur Khairi, Nur Khairuddin - Khairuddin Khairuddin Khairuddin Khairuddin Kristina Pasongli Lisa Christine Maghfirah Putri Arifin Marliana Pasang Marliana Pasang, Marliana Martinus G Lalu Marwati Marwati Marwati Marwati Marwati Marwati Mar’atun Jannah, Imrawati, Muzakkir Baitz, Maulita Indrisari, Maulita Maya M. Mangande Megawati - Megawati Megawati Megawati Megawati Megawati Megawati Michrun Nisa Mubarak Mubarak Muhammad Aswad Muhammad Aswad Muhammad Aswad Muhammad Mirwan Mus, Suwahyuni Muslimin, Lukman Muttaqin, Fauzan Zein Noer Fauziah Rahman Noer Rahman Nur Rahma Rumata Nur Syam Hidayah Rahma Ismail paluseri, Andi Pasongli, Kristina Radhia R Radhia R, Radhia Rahmad Aksa Rifah Yulianty Risfah Yulianti Rosyid, Sujud Z Sahibuddin A Gani Sahibuddin A Gani Sahibuddin A Gani, Sahibuddin A Sami, Fitriyanti Sami, Fitriyanti J. Sitti Rahmi Slamet Ibrahim Solly Aryza Subehan Lallo Suhaimi Azizah Sukriani Kursia Sukriani Kursia, Sukriani Suwahyuni Mus Syamsu Nur Syamsu Nur Syamsu Nur, Syamsu Tumigolung, Aprilia Ester Eunike Utami, Novi F. Wahyu Hendrarti Wahyu Hendrarti William Johanes Dian Patabang Yulita M. Soko