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All Journal Jurnal Mandala Pharmacon Indonesia Majalah Farmasetika Journal Borneo Jurnal Farmasi Sains dan Praktis Jurnal Pengabdian Nusantara (JPN) Lansau: Jurnal Ilmu Kefarmasian Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Indonesian Journal of Community Empowerment Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Jurnal Sains dan Kesehatan Journal of Pharmaceutical and Natural Resources
Astrid Indalifiany
Departemen Farmasi, Fakultas Farmasi, Universitas Halu Oleo, Sulawesi Tenggara, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Formulasi Spray Gel Ekstrak Etanol Batang Etlingera rubroloba Menggunakan HPMC sebagai Gelling Agent: Formulation Spray Gel of Etlingera rubroloba Ethanolic Extract Using HPMC as Gelling Agent Astrid Indalifiany; Waode Sitti Zubaydah; Elvira Riskiyani Kasim
Jurnal Sains dan Kesehatan Vol. 5 No. 2 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i2.1729

Abstract

Herbal plants are one source of discovering secondary metabolites for active ingredients in medicine and one of them is Etlingera rubroloba from the Zingiberaceae group. The stems of these plants contain polyphenols as natural antioxidants. Application of natural antioxidants can be given topically through spray gel preparations. Spray preparations in gel form using HPMC can produce clear visuals, stable viscosity and do not irritate the skin. This study aims to obtain the optimal concentration of HPMC in the manufacture of E.rubroloba ethanol extract spray gel in terms of the resulting evaluation and physical stability. Formulation of spray gel based on the experimental method of optimizing gel base by adding E.rubroloba ethanol extract in various concentrations of HPMC 0.1% (F1); 0.2% (F2); 0.3% (F3) ; 0.4% (F4); and 0.5% (F5). The results showed that F1 with 0.1% HPMC had the best physical properties and stability of the preparation with a clear organoleptic, characteristic odor, and slightly viscous, producing a homogeneous spray gel, having a pH of 6, viscosity of 60 cps, spray weight of 0.13 gram, dry time 1.14 minutes, pattern and diameter of spraying spread well, and physically stable through centrifugation method stability test and cycling test. Keywords: Antioxidant, Etlingera rubroloba, gel, HPMC Abstrak Tumbuhan herbal merupakan salah satu sumber penemuan metabolit sekunder untuk bahan aktif dalam pengobatan dan salah satunya adalah Etlingera rubroloba dari kelompok Zingiberaceae. Batang tumbuhan tersebut mengandung polifenol sebagai antioksidan alami. Aplikasi antioksidan alami dapat diberikan secara topikal melalui sediaan spray gel. Sediaan spray dalam bentuk gel menggunakan HPMC dapat menghasilkan visual jernih, viskositas stabil dan tidak mengiritasi kulit. Penelitian ini bertujuan untuk mendapatkan konsentrasi optimal HPMC dalam pembuatan spray gel ekstrak etanol E.rubroloba yang ditinjau dari evaluasi dan stabilitas fisik yang dihasilkan. Formulasi sediaan spray gel berdasarkan metode eksperimental optimalisasi basis gel dengan menambahkan ekstrak etanol E.rubroloba dalam variasi konsentrasi HPMC 0,1% (F1) ; 0,2% (F2); 0,3% (F3) ; 0,4% (F4); dan 0,5% (F5). Hasil penelitian menunjukkan bahwa F1 dengan HPMC 0,1% memiliki sifat fisik dan stabilitas sediaan terbaik dengan organoleptik bening, berbau khas, dan agak kental, menghasilkan spray gel yang homogen, memiliki pH 6, viskositas 60 cps, bobot semprot 0,13 gram, waktu kering 1,14 menit, pola dan diameter penyemprotan menyebar dengan baik, serta stabil secara fisik melalui uji stabilitas metode sentrifugasi dan cycling test. Kata Kunci: Antioksidan, Etlingera rubroloba, gel, HPMC
Formulasi Gel dari Niosom Elastik Span 80 Ekstrak Etanol Rimpang Etlingera alba dengan Variasi Karbopol sebagai Gelling Agent: Formulation Gel of Span 80 Elastic Niosome of Etlingera alba’s Rhizomes Ethanolic Extract with Carbopol Variations as Gelling Agent Astrid Indalifiany; Suryani Suryani; Vica Aspadiah; Rifa’atul Mahmudah; Rezki Annisa
Jurnal Sains dan Kesehatan Vol. 5 No. 5 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i5.2000

Abstract

Free radicals contain at least one or more free electrons, so they are reactive and unstable. Several diseases experience increased oxidative stress due to the stability of free radicals, which has the potential to damage the integrity of DNA, proteins, and lipids. The body's ability to accumulate free radicals can be stopped with natural antioxidants. One plant with antioxidant potential is Etlingera alba. Utilization of potential is carried out through the preparation of elastic niosomes from the ethanol extract of E. alba rhizomes using Span 80 so that it can facilitate this natural material transdermally. Gel preparations with carbopol as a gelling agent can be used in the application of E. alba ethanol extract elastic niosomes to the skin. The aim of this research was to make an elastic niosome gel with optimal concentrations of Span 80 and carbopol. Elastic niosomes were characterized through morphology, particle size, and polydispersity index. The results of the characterization of elastic niosomes showed that FD (Span 80 15%) produced the best elastic niosomes with an average vesicle size of 10.43 nm, polydispersity index of 0.282, and spherical shape. Elastic niosome gel preparations were evaluated through organoleptic, pH, viscosity, spreadability, and physical stability using cycling tests. The evaluation results showed that F1 gel (carbopol 0.5%) produced the best physical properties of the gel with organoleptic viscosity, characteristic odor and white, pH 6, viscosity 2,433 cps, and spreadability 6.6 cm and was physically stable through method testing. cycling-test. Keywords:          Niosome, Etlingera, Span 80, Carbopol, Nanoparticle   Abstrak Radikal bebas mengandung setidaknya satu/lebih elektron bebas, sehingga reaktif dan tidak stabil. Beberapa penyakit mengalami peningkatan stres oksidatif akibat tercapainya stabilitas radikal bebas sehingga berpotensi merusak integritas DNA, protein, dan lipid. Kemampuan tubuh dalam mengakumulasi radikal bebas dapat dihentikan dengan antioksidan alami. Salah satu tumbuhan dengan potensi antioksidan adalah Etlingera alba. Pemanfaatan potensi dilakukan melalui preparasi niosom elastik ekstrak etanol rimpang E.alba menggunakan Span 80 sehingga dapat memfasilitasi bahan alam tersebut secara transdermal. Sediaan gel dengan karbopol sebagai gelling agent dapat digunakan dalam aplikasi niosom elastik ekstrak etanol E. alba pada kulit. Tujuan dari penelitian ini adalah untuk membuat gel niosom elastik dengan konsentrasi Span 80 dan karbopol yang optimal. Niosom elastik dikarakterisasi melalui morfologi, ukuran partikel dan indeks polidispersitas. Hasil karakterisasi niosom elastik diperoleh bahwa FD (Span 80 15%) menghasilkan niosom elastik terbaik dengan rata-rata ukuran vesikel 10,43 nm, indeks-polidispersitas 0,282, dan bentuk sferis. Sediaan gel niosom elastik dievaluasi melalui organoleptik, pH, viskositas, daya-sebar dan stabilitas fisik dengan cycling test. Hasil evaluasi diperoleh bahwa gel F1 (karbopol 0,5%) menghasilkan sifat fisik gel terbaik dengan organoleptik kental, bau khas, dan putih, pH 6, viskositas 2.433cps, dan daya-sebar 6,6 cm serta stabil secara fisik melalui pengujian metode cycling-test. Kata Kunci:         Niosom, Etlingera, Span 80, Karbopol, Nanopartikel
Optimization of Tween 80 and Span 80 Combination in the Formulation of Niacinamide-Containing Body Lotion Vica Aspadiah; Nur Illiyyin Akib; Astrid Indalifiany; Rahmat Muliadi; Reza Rosita Layuk
Journal of Pharmaceutical and Natural Resources Vol. 1 No. 1 (2025): Journal of Pharmaceutical and Natural Resources
Publisher : Jurusan Farmasi Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpnar.v1i1.pp1-7

Abstract

Body lotion is a liquid emulsion preparation consisting of an oil phase and a water phase stabilized by emulsifiers, functioning to maintain skin moisture and provide protection. One of the most widely used active ingredients in current cosmetic formulations is niacinamide, known for its effectiveness in brightening the skin, enhancing the skin barrier function, and reducing hyperpigmentation. The success of a body lotion formulation depends largely on the appropriate selection and concentration of emulsifiers to achieve emulsion stability and optimal physical characteristics. This study aimed to optimize the combination of Tween 80 and Span 80 emulsifiers in a body lotion formulation containing niacinamide using a 2² factorial design method with the assistance of Design-Expert software. The formulation was evaluated based on several physical parameters, including pH, adhesiveness, spreadability, viscosity, homogeneity, emulsion type, and physical stability, as well as a hedonic test assessing color, odor, and texture. Optimization results indicated that the best formulation was obtained from a combination of 1% Tween 80 and 10% Span 80. The resulting product had a pH of 6.4, adhesiveness of 112 seconds, spreadability of 6.1 cm, viscosity of 16,568.3 cps, good homogeneity, and demonstrated a stable oil-in-water (O/W) emulsion type without phase separation. Therefore, the optimum combination of Tween 80 and Span 80 in concentrations of 1% and 10%, respectively, yields a physically stable niacinamide-containing body lotion.
PENINGKATAN LITERASI MASYARAKAT TENTANG PENGGUNAAN SUNSCREEN SEBAGAI UPAYA PENCEGAHAN PHOTOAGING DI KELURAHAN ANDUONOHU KENDARI Astrid Indalifiany; Asniar Pascayantri; Vica Aspadiah; Rahmat Muliadi; Adibah Nailal Husna; Nabilah Dwijayanti Suleman; Nur Halimah Mutmainah; Sitti Ruhiyat; Tri Wilda Bahir; Atia Fauziah; Sitti Nurjannah; Azzahra Asmaya
MAJU : Indonesian Journal of Community Empowerment Vol. 3 No. 3 (2026): MAJU : Indonesian Journal of Community Empowerment, Mei 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/maju.v3i3.2569

Abstract

High ultraviolet (UV) exposure in tropical regions increases the risk of premature skin aging (photoaging), while public awareness regarding proper sunscreen use remains limited. This community service program aimed to improve community literacy on sunscreen use as an effort to prevent photoaging. The program was conducted in Anduonohu Village, Kendari City through door-to-door education, interactive counseling, sunscreen application demonstrations, leaflet distribution, and evaluation using post-tests and direct discussions. Educational materials included the dangers of UV exposure, selection of SPF and PA, correct sunscreen application techniques, and the importance of reapplication. The results showed an improvement in participants’ understanding and awareness regarding daily sunscreen use. Post-test evaluation indicated that 70% of participants experienced increased knowledge and behavioral changes related to sunscreen use. This activity demonstrates that personal and demonstrative educational approaches are effective in improving community skin health literacy.
IMPLEMENTASI PROGRAM DAGUSIBU MELALUI PENDEKATAN LEAFLET DALAM MENINGKATKAN PENGETAHUAN MASYARAKAT KELURAHAN WATU-WATU TENTANG AKSES DAN PEROLEHAN OBAT YANG TEPAT Asniar Pascayantri; Adryan Fristiohady; Irnawati Irnawati; Asriullah Jabbar; Sabarudin Sabarudin; Hasnawati Hasnawati; Nur Illyin; Astrid Indalifiany; Fadhliyah Malik; Vica Aspadiah; Rahmat Mualiadi; Dian Munasari Solo; La Ode Muhammad Fitrawan; Nasrudin Nasrudin; Ari sartinah; Muhammad Ilyas Y; Mubarak Mubarak
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 5 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Mei 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i5.2570

Abstract

Low drug literacy can lead to drug misuse, irrational self-medication, and the procurement of medicines from unofficial sources. This community service activity aimed to improve the knowledge of Watu-Watu Village residents on proper drug access and acquisition through the DAGUSIBU program, using educational leaflets, discussions, and interactive question-and-answer sessions. Program effectiveness was measured using pre- and post-tests, as well as Likert-scale evaluations. Results showed an increase in community knowledge from 61% to 100%, and the program received a mean evaluation score of 4.83 out of 5. The leaflet-based DAGUSIBU program, combined with active interaction, effectively improved community drug literacy and can serve as a replicable model for community-based pharmaceutical education.
Co-Authors ,, Suryani Adibah Nailal Husna Adryan Fristiohadi Adryan Fristiohady Ari Sartinah Asniar Pascayantri Aspadiah, Vica Asriullah Jabbar Asriullah Jabbar Atia Fauziah Azzahra Asmaya Bafadal, Mentarry Bahari Bahari Dian Munasari Dian Munasari Dian Munasari Solo Doddy Ismunandar Bahari Elfahmi Elfahmi, Elfahmi Elvira Riskiyani Kasim Fadhliyah Malik Fifi Nirmala Fitrawan, La Ode Muhammad Fristiohady, Adryan Halik Halik Hasnawati Hasnawati Husnaeni Husnaeni Irnawati Irnawati La Ode Muh. Fitrawan La Ode Nggawu Listha Magistia Muamar Abdillah Mubarak Mubarak Muhammad Hajrul Malaka Muhammad Hajrul Malaka Muhammad Handoyo Sahumena Muhammad Ilyas Y Muhammad Ilyas Y Muhammad Israwan Azis Nabilah Dwijayanti Suleman Nasrudin Nasrudin Norma Arif Nur Halimah Mutmainah Nur Illiyyin Akib Nur Illyin Nurull Hikmah Rahmat Mualiadi RAHMAT MULIADI, RAHMAT Reza Rosita Layuk Rezki Annisa Rifa’atul Mahmudah Rina Andriani Rina Andriani Rina Andryani Rini Novianti Sabarudin Sabarudin Sahidin Sahidin Sahidin Sahidin Sahidin Sahidin Sahidin Sitti Nurjannah Sitti Raodah Nurul Jannah Sitti Ruhiyat Suriana Suriana Tian Amalia Halik Tjandra Buana Tri Wilda Bahir Vica Aspadiah Vica Aspadiah Wa Ode Erna Fitriani Wa Ode Sitti Zubaydah Wahyuni Wahyuni WOS Zubaydah WOS Zubaydah WOS Zubaydah Yamin Yodha, Agung Wibawa Mahatva