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Journal : Medula

Tinjauan Pustaka: Pengaruh Hipertensi Kronis pada Ibu Hamil terhadap Kejadian Preeklampsia Putri, Morica Angellia Shyama; Kurniati, Intanri; Putri, Giska Tri; Kurniawati, Evi
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1458

Abstract

Chronic hypertension in pregnant women is a medical condition that can significantly affect maternal and fetal health. Chronic hypertension is defined as high blood pressure that has been present before pregnancy or diagnosed before 20 weeks of gestation. Risk factors that affect this condition include older maternal age, obesity, family history of hypertension, and an unhealthy lifestyle. The pathophysiology of chronic hypertension that progresses to preeclampsia involves endothelial dysfunction, which causes vasoconstriction and decreased placental perfusion, leading to placental hypoxia and increased oxidative stress, which further triggers activation of systemic inflammatory pathways causing damage to target organs such as the kidneys (proteinuria) and liver (elevated liver enzymes). The prevalence of chronic hypertension in pregnant women in Indonesia is quite high. According to data from the Lampung Provincial Health Office in 2018, hypertension in pregnancy caused 15.16% of maternal deaths. In addition, data from Riskesdas 2018 shows that the prevalence of hypertension in pregnant women in Indonesia is 6.18%, with the highest prevalence in West Java Province at 10.57%. The purpose of this article is to provide a better understanding of the effect of chronic hypertension in pregnant women on the incidence of preeclampsia. This article will discuss the association of chronic hypertension with the risk and underlying mechanisms of preeclampsia.
Gagal Jantung pada Penyakit Jantung Bawaan Nabila, Nurahma; Putri, Giska Tri
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1461

Abstract

Congenital heart disease (CHD) is one of the most common causes of death due to malformations during the embryonic organogenesis process. The survival rate of patients with this disease has increased due to advancements in therapeutic options. Although the success of surgical and medical management of congenital heart disease (CHD) has been very successful, some patients still have hemodynamic abnormalities that lead to long-term cardiovascular complications. One of the complications that causes death in patients with congenital heart disease (CHD) is heart failure. Heart failure in children with congenital heart disease has a 20-fold risk of death, while heart failure in adults has a 25% incidence in patients with congenital heart disease at the age of 30, and this risk increases with age. Because this condition can cause disorders such as growth and cognitive failure, but can also be associated with circulatory, neurohormonal, and molecular abnormalities. The challenge in addressing the risk of morbidity and mortality is related to the limited knowledge regarding the causes of congenital heart disease (CHD), and current evidence suggests etiologi such as unclear factors, including the environment and lifestyle of parents, as well as genetics passed down to the child. This review discusses the causes, epidemiology, and manifestations of heart failure in children and adults with congenital heart disease. The purpose of this review is to understand the epidemiology, classification, clinical manifestations, pathophysiology, and management of heart failure in patients with congenital heart disease.
LOW BACK PAIN: Literature Review Shafia, Anindya; Ismunandar, Helmi; Putri, Giska Tri; Saftarina, Fitria
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1631

Abstract

Low back pain (LBP) is one of the most common musculoskeletal problems and a leading cause of disability and global productivity loss. This condition can be either acute or chronic and is caused by various factors, including mechanical, radicular, and nociplastic components. The complexity of its etiology and the variability of treatment responses necessitate a comprehensive and multidimensional approach. This study is a literature review that examines scientific articles obtained from databases such as PubMed, Scopus, and Google Scholar. The articles reviewed were published between 2015-2025 and discussed aspects of  definition, epidemiology, classification, diagnosis, and pharmacological and non-pharmacological management of LBP. The review found that LBP has a high global prevalence, particularly among the productive age group and the elderly. Risk factors include biomechanical, psychosocial, and lifestyle aspects. Management of LBP involves pharmacological treatments (NSAIDs, tramadol, duloxetine) and non-pharmacological approaches (physical exercise, education, multidisciplinary rehabilitation). LBP is a complex public health issue with significant economic and social burdens. Effective management strategies require a biopsychosocial approach, appropriate use of screening tools, and multifactorial interventions tailored to the type and phase of pain. Prevention through education and physical activity has also proven effective in reducing the risk of LBP occurrence.
PENATALAKSANAAN PADA NY. I USIA 54 TAHUN DENGAN DIABETES MELITUS TIPE 2 DAN DISLIPIDEMIA MELALUI PENDEKATAN KEDOKTERAN KELUARGA DI PUSKESMAS GEDONG TATAAN Utami, Nabila Rachmadita; Aliffia Bingga, Isvi; Saftarina, Fitria; Putri, Giska Tri
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1155

Abstract

Diseases in Indonesia can generally be divided into communicable diseases and non-communicable diseases. Based on Riskesdas data, the number of DM suffers in Indonesia is increasing every year. In Indonesia, the prevalence of dislipidemia increase to 15.5% in the 55-64 year age group. Of these, 80% of patients died suddenly due to a heart attack, and 20% showed no symptoms. Patients must know about their disease and have awareness and motivation to make lifestyle modifications so that treatment goals can be achieved, so management is needed through a family approach. Application of evidence-based medicine-based family doctor services to patients by identifying risk factors, clinical problems, and patient management based on the patient's problem-solving framework with a patient centered approach and a family approach. This study is a case report. Primary data were obtained through anamnesis, physical examination and home visits to assess the physical environment. Secondary data were obtained from patient medical records. Assessments are based on a holistic diagnosis from the start, process, and end of the study in a qualitative and quantitative manner. Mrs. I, 54 years old with type 2 diabetes mellitus (DM) and dyslipidemia, was worried that his complaints would get worse and not improve. Limited knowledge about the patient's health condition in the form of causative factors, prevention of type 2 DM and dyslipidemia, foods that need to be avoided and the lack of motivation and encouragement from families to bring patients for routine health control are factors that cause problems that occur in patients and families. Holistic and comprehensive management of the problems patient named as Mrs. I  has been carried out by providing counseling to increase the knowledge of patients and their families.
Hemorrhagic Stroke in Patients with a History of Ischemic Stroke Irawan, Wildan Kautsar; Fitriyani, Fitriyani; Putri, Giska Tri
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.901

Abstract

Stroke is an acute neurological disorder characterized by disruption of the blood supply to the brain, either due to obstruction or bleeding. Stroke is currently still a health problem that causes many disabilities and deaths in Indonesia. Stroke can also cause economic problems because of the disability that arises as a result of stroke and the funds that must be allocated to treat stroke in the national health system. One of the complications of stroke that can occur is recurrent stroke. This study aims to systematically establish a diagnosis in a 42 year old female patient so that the patient can be treated appropriately. The method used is a case report with analysis of primary data obtained through autoanamnesis, alloanamnesis, physical examination and supporting examinations. A 42 year old woman came with complaints of decreased consciousness accompanied by headache, nausea, vomiting, and weakness in the left limbs. The patient had experienced a non-hemorrhagic stroke 3 years ago. The patient was diagnosed with hypertension 7 years ago, the hypertension was not controlled and the patient did not take medication. The patient in this case was diagnosed with hemorrhagic stroke with a history of ischemic stroke. Patients are managed with non-medical, medical and rehabilitative management. In non-medical management, bed rest is performed. Medical management was given mannitol 250/125/125 every 8 hours, domperidone 3x10mg, sucralfate 3x2c, amlodipine 5 mg at night, lisinopril 5 mg in the morning, and paracetamol 3x1000 mg. The patient also underwent physiotherapy.
A case report Space Occupying Lesion Pamarta, Alma Abigail; Fitriyani, Fitriyani; Putri, Giska Tri
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.906

Abstract

Space Occupied Lession (SOL) is a substantial physical lesion, such as neoplasm, bleeding, or granuloma located in the skull cavity. The most common causes of increased intracranial pressure in neurological cases are brain trauma, brain tumors, inflammation, and hydrocephalus. Mrs. SU, 46 years old, 17 November 2023 MRS with complaints of sudden unconsciousness since this morning, approximately 15 hours SMRS. Initially the patient complained of a severe headache accompanied by nausea and vomiting. The patient has a history of headaches for many years that have become worse for the past 3 days. To overcome headaches, patients often take paracetamol. Additional complaints: left eyelid closes and swells and cannot see at all. The patient had never previously experienced decreased consciousness. When he arrived, the patient's general condition appeared to be moderately ill with somnolence with a GCS of 9 (E2 V2 M5). Blood pressure 145/95 mmHg. After observation the next day, awareness of apathy with GCS 13 (E3 V4 M5). Blood pressure was 132/85 mmHg, on physical examination there was left ptosis and left eyelid edema. On visual acuity examination, the visual acuity was 3/60 and the left oculi was 1/. The pupil is round, anisocoric, with a central position. Nystagmus in the left oculi is positive. From the supporting examination, namely a CT scan, it was found that there was an amorphous isodense lesion with ill-defined boundaries in the left frontotemporal lobe measuring 6.5 cm x 5.4 cm with minimal perifocal edema, suspected of glioma, which deviated from the midline to the right as far as 0.5. cm. The patient's clinical diagnosis was increased intracranial pressure in the frontotemporal with the etiology of SOL caused by hydrocephalus. Management for this patient is medical treatment, namely: IV FD NaCl 0.9% 20 gtt/minute, Dexametson 1 ampoule/8 hours, Mannitol 250cc – 125cc – 75cc – 50 cc, Paracetamol 500 mg 3x1, Ceftriaxon 1 gr/12 hours, B12 2x1. VP-Shunt installation. For patients with a diagnosis of increased intracranial pressure caused by SOL and hydrocephalus, medical management and VP-Shunt installation will result in a good prognosis.