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All Journal Jurnal Kesehatan Andalas Majalah Obat Tradisional Media Ilmu Kesehatan Majalah Kedokteran Andalas Jurnal Sehat Mandiri Bioscientia Medicina : Journal of Biomedicine and Translational Research Andalas obstetrics and gynecology journal Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) SENTRI: Jurnal Riset Ilmiah Innovative: Journal Of Social Science Research Jurnal Riset Ilmiah Jurnal Akademika Baiturrahim Jambi
Zelly Dia Rofinda
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Aerospace Engineering Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Jurnal Riset Ilmiah

 1 
GAMBARAN ANALISIS HEMOGLOBIN PASIEN DENGAN DUGAAN TALASEMIA Β MAYOR YANG DIRAWAT INAP DI RSUP DR. M. DJAMIL PADANG Azura, Rahla; Rofinda, Zelly Dia; Rusjdi, Selfi Renita; Husni, Husni; Mahata, Liganda Endo; Fadila, Zurayya
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 5 (2025): SINERGI : Jurnal Riset Ilmiah, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i5.1218

Abstract

Background: Beta thalassemia major is a genetic blood disorder inherited by parents thalassemia traits (carrier) characterized by abnormal hemoglobin formation. Abnormalities during the process of hemoglobin formation cause gene changes or mutations that cause symptoms of severe anemia which has a long-term clinical impact on patients. High performance liquid chromatography can be used to determine the description of abnormal hemoglobin analysis, thus suspected diagnosis of thalassemia β major can be established by the clinician as a definitive diagnosis to enhance a more comprehensive diagnosis. Primary theraphy of beta thalassemia major is blood transfusion to support the quality of life regularly throughout the patient's life, transfusion of patients requires measurements such as pre-transfusion hemoglobin levels.  Objective: This study aims to determine the description of the results of the analysis of hemoglobin patients with suspected thalassemia beta major at RSUP Dr. M. Djamil Padang. Methods: This study used a cross sectional design.  The sampling technique uses total sampling with a total sample of 19 people from 1-35 years old. Patient data was from the suspected diagnosis of medical records established by clinicians at Dr. M. Djamil Hospital Padang. This data was analyzed univariately. Results: The results of this study indicated is mostly female with an average age of 13,74 years (SD ±12.1). This study resulted in a low pretransfusion hemoglobin average of 6.20 g/dL. The results of hemoglobin analysis for beta thalassemia major with average HbA (48,1%), HbA2 (27,3%) and HbF (24,5%). Conclusion: The results of the examination hemoglobin analysis on the HPLC method had results that did not compatible predictions of the suspected diagnosis of beta thalassemia major from the clinician
Co-Authors Adrial Adrial, Adrial Afdal Afdal, Afdal Afriwardi Afriwardi Aisah Aisah Aisyah Elliyanti Alfitri, Maura Salsabila Alinia, Hessa Sena Almurdi Almurdi Alvarino Alvarino Ami Tri Nursasmi Amirah Zatil Izzah Aprilia, Dinda Arina Widya Murni Ashal, Taufik Aswiyanti Asri Atmi, Serly Rahma Azahra, Azizah Firda Azura, Rahla Beni Indra, Beni Bobby Indra Utama Desiekawati Desmawati Desmawati Dessy Arisanti Deswita Sari Desywar Dian Pertiwi Dian Pertiwi Dwi Yulia Dwitya Elvira, Dwitya Efrida Efrida Elfira Yusri Elizabeth Bahar Elmatris Sy Endrinaldi Eti Yerizel Etriyel Myh Eva Decroli Evynatra, Evynatra Fadhillah, Ilham Arief Fadila, Zurayya Fathiyyatul Khaira, Fathiyyatul Fereshti Lailani Finny Fitry Yani Gestina Aliska Hasmiwati Herinda, Dwi Putri Hessa Sena Alinia Hirowati Ali, Hirowati Husni Husni Husni Ihsan, Indra Julizar Nazar Khaulah Karimah Kurniawan Lili Novri Yanti Mahata, Liganda Endo Masnadi, Nice Rachmawati Masrul Mohamad Reza Mulya, Fiona Septi Nur Indrawaty Lipoeto Nurhajjah, Sitti Prima Astuti Handayani Purwati, Desta Rahmatini . Rahmi Dina Indra Rahmi, Yannisa Mutiara Rauza Sukma Rita Reza, Mohamad Rikarni Rikarni Rikarni Rismawati Yaswir Rosfita Rasyid Rudy Afriant Santril, Nitri Ramadhani Sari, Deswita Selfi Renita Rusjdi Suchitra, Avit Syofiati Ulya Uti Fasrini Wahyuni, Febby Genta Yashinta Octavian Gita Setyanda Yoshie Anto Chicamy Yufani, Hevrina Yulia Margaretta Sari Yulia, Dwi Yulistini, Yulistini Yusri, Elfira Zahira, Aisyah Dhia zahra salsabila Zulmitra, Elsa