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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Bioma : Berkala Ilmiah Biologi Jurnal Medika Malahayati Jurnal Farmasi Higea Jurnal Midpro Jurnal Ilmiah Kesehatan Masyarakat : Media Komunikasi Komunitas Kesehatan Masyarakat Keluwih: Jurnal Kesehatan dan Kedokteran Sainstech Farma: Jurnal Ilmu Kefarmasian Borneo Journal Of Pharmascientech INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Bina Pengabdian Kepada Masyarakat Pharmaceutical And Biomedical Sciences Journal (PBSJ) Prosiding Konferensi Nasional PKM-CSR Jurnal Inkofar Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Jurnal Pengabdian Masyarakat Kesosi Mestaka: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Bangsa Herbal Medicine Journal Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia GEMBIRA (Pengabdian Kepada Masyarakat) PEDAMAS (Pengabdian Kepada Masyarakat) Law and Justice Borneo Journal of Pharmacy Journal of Transcendental Law JCSE: Journal of Community Service and Empowerment Masyarakat: Jurnal Pengabdian Fundamental : Jurnal Ilmiah Hukum Jurnal Kesehatan Masa Depan Menulis: Jurnal Penelitian Nusantara Journal Pharmaceutical Science and Application (JPSA)
Ainun Wulandari
Fakultas Farmasi, Institut Sains Dan Teknologi Nasional
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Evaluasi Pemberian dan Penggunaan Obat Antihipertensi pada Pasien Lansia di Puskesmas Sukarami Palembang Wulandari, Ainun; Ardhianingsih, Vira
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 5 No. 2 (2021)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v5i2.1919

Abstract

Hipertensi atau tekanan darah tinggi adalah peningkatan tekanan darah sistolik lebih dari 140 mmHg dan tekanan darah diastolik lebih dari 90 mmHg pada dua kali pengukuran dengan selang waktu lima menit dalam keadaan cukup istirahat/tenang. Hipertensi masih menjadi salah satu penyakit yang prevalensinya mengalami peningkatan. Tujuan dari penelitian ini adalah untuk mengetahui profil pengobatan dan kesesuaian pemberian obat antihipertensi pada pasien lansia di Puskesmas Sukarami Palembang tahun 2020. Penelitian ini merupakan penelitian non eksperimental dengan metode deskriptif dan pengambilan data secara retrospektif. Data diambil dari rekam medis pasien di Puskesmas Sukarami Palembang tahun 2020. Hasil penelitian menggunakan 72 sampel, didapatkan hasil bahwa kebanyakan pasien dalam penelitian ini, berjenis kelamin laki-laki (54,17%), usia kisaran 60-74 tahun (91,67%), dengan terbanyak hipertensi stage II (65,28%) serta penyakit penyerta terbanyak yaitu diabetes mellitus (15,28%). Golongan obat antihipertensi terbanyak yaitu CCB dengan obat terbanyak amlodipin (94,44%). Pola terapi paling banyak yaitu monoterapi golongan CCB amlodipin (94,44%), penggunaan politerapi dua obat dengan kombinasi terbanyak yaitu golongan CCB dan ACEI (4,17%). Kesesuaian pemilihan obat antihipertensi seluruh pasien dikatakan sesuai dengan JNC 8 (100%) dan kesesuaian pemilihan dosis obat antihipertensi dengan JNC 8 sebanyak 69 pasien (95,83%) dan dosis terlalu tinggi sebanyak 3 pasien (4,17%).
EFFECTIVENESS OF BRONCHODILATOR AND CORTICOSTEROID TREATMENT IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) Putu Rika Veryanti; Ainun Wulandari
Journal Pharmaceutical Science and Application Vol. 2 No. 1 (2020): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2020.v02.i01.p03

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a chronic airway disease which is characterized by progressive airway obstruction. Bronchodilators and corticosteroids are the first choices of therapy in COPD patients. The goal therapy of COPD patients is to prevent respiratory failure, which can impact on death. But nowadays, the mortality rate due to COPD continues to increase. WHO predicts mortality from COPD in the year 2030 will be ranked third in the world. This high mortality can be caused by the ineffectiveness of therapy given. Objective: The aim of this study is to find out the effectiveness of bronchodilator and corticosteroid treatments in COPD patients. Methods: An observational study conducted retrospectively in the 2018 period at Fatmawati Central General Hospital. The effectiveness of therapy was assessed from the patient's clinical condition, blood gas values (PaO2 & PaCO2) and the average length of stay (AvLOS). Results: COPD was mostly suffered by males (83,33%), and the highest age for COPD was in the range of 45 years and above (90%). Bronchodilator that commonly prescribed were albuterol (30.08%), ipratropium bromide (12.2%), fenoterol hydrobromide (10.57%), terbutaline sulfate (8.13%), theophylline (1.63%) and aminophylline (5.69%), while the corticosteroids were budesonide (17.07%), methylprednisolone (9.76%) and dexamethasone (4.88%). Bronchodilator and corticosteroid had improved patient's clinical condition (96.67% patients) and also improved PaO2 & PaCO2 values patients. There was a significant improvement in PaO2 and PaCO2 value in COPD patients (p <0.05). Conclusion: Bronchodilator and corticosteroid in COPD patients had improved patient's clinical condition and PaO2 & PaCO2 values, but the average length of stay exceeds the standard (6-9 days). Keywords: Bronchodilator; Corticosteroid; COPD; Blood Gas Analysis; Average Length of Stay
Co-Authors Aditya Fitriasari Aditya Fitriasari Adnan Adnan Adrully El Fienda Ahamd Syaifil Iman Akhatik, Nurul Alladin, Dwi Amalia Khoirunnisa Aminudin, Iwan Andini, Issri Mila Nova Ardhianingsih, Vira Ardhianingsih, Vira Arum, Fitria Diah Dea Selia Dienillah, Qonita Dini Juliana Diny Auliya Mawarni Djuhariah, Yayah Siti Dwi Okta Mellya Edy Meiyanto Erham Erwi Putri Setyaningsih Ester Marintan Purba Fadly, Iqbal Faraidlika Fara Diana Dewi Fathin Hamida Febriani, Amelia Fiandani, Afifah Fina Aryani Goenadi Fina Aryani Goenadi, Fina Aryani Firdha Aprilya Utami Firmanto, Taufik Fitria Rahayu Fitria Yustisiani Gufran, Gufran Herdini Herdini , Herdini Hervianti Nurfitria Nugrahani Heryanto, Anas Hindrayani, Woro Hutagaol, Sartika Ika Maruya Kusuma Iksan Iksan ILHAM Illahi, Sakinah Ayu Ilyas Ilyas sarbini Indra Wani Irawansah, Didik Januarto, Daniel Jaya, Rendy Indra Jerry, Jerry Jessica Khairunnisa Kartika Dyah Palupi Kartika Dyah Palupi Kartin Aprianti Kasmar , Kasmar Khairiah, Ardian Kholid Alfan Nur Kholid Alfan Nur Khulqiyah, Husnul Kinanthi Kusumawardhani Krisnawati, Indah Kusuma, Ika Maruya Lestiana, Elina Lidia Anggita Ramadhani Lili Musnelina Loamena, Raisul Amin M. Farhan Syauki M. Yahya Madhani, Suci Marsa Falihah Masrin, Masrin Maulana, Arif Andy Maulana, M. Rizky Mira Permata Miskun, Miskun Muh Asad Imaduddin Muh. Faris Hidayat Muhammad Amin Mulandita Munawarohthus Sholikha Munawarohthus Sholikha Munawarohthus Sholikhah Nasrullah Nasrullah Nastion, Nastion Ni’matul Khoeriyah Nopianti, Hermila Nugrahani, Hervianti Nurfitria Nurul Akhatik Nusantara, Ari Fahimatussyam Putra Oktari, Anggi Irma Yani Pontoan, Jenny Pratiwi Ally Florentina Putra, Anis Fuady Surya Putri , Elvina Triana Putri, Clarisya Pramirusanti Putri, Elvina Triana Rachmatiah, Tiah Rahmawardany, Claudia Y Ramadhani, Lidia Anggita Ratna Nilam Cahya Refdanita Refdanita Refdanita Refdanita, Refdanita Resi Sukma Melati Rianty, Ira Ridwan Ridwan Ridwan, Ridwan Risma Eka Putri Ritha Widyapratiwi Rivita, Maisya Rogahang, Preisilia Rosario Trijuliamos Manalu Sahidah, Sahidah Saiful Bahri Saiful Bahri Saputri, Ika Septiyani Monalisa Setiadi, Fandy Rezha Shella Utami Siregar, Tahoma Siswati Siswati Siti Fadila Azahra Sonia Mutiara Subaryanti Subaryanti, Subaryanti Suci Tiara Sukirman Sukirman Syafriana, Vilya Teodhora, Teodhora Teti Indrawati Teti Indrawati Tiah Rachmatiah Tongat Tongat Tri Soehartati Vahlevi, Rizky Reza Veriyanti , Putu Rika Veryanti, Putu Rika Welisa, Selfina Junita Widyapratiwi, Ritha Winahayu, Neng Esti Windiarto, Henriko Suryo Wiwik Handayani Yayah Siti Djuhariah Yunisa Simehete Yunita Kartini Zabitha Zahwa Zaini, Jamal Zuhrah