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All Journal JURNAL PENELITIAN SAINTIKA Jurnal Hasil Penelitian Industri Jurnal Surya Medika AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT PREPOTIF : Jurnal Kesehatan Masyarakat Science Midwifery Journal of Pharmaceutical and Health Research International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Chemical Science and Technology Jurnal Kesehatan Tambusai JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal Farmanesia IKA BINA EN PABOLO : PENGABDIAN KEPADA MASYARAKAT Journal of Health and Medical Science International Journal of Health and Pharmaceutical (IJHP) Eduvest - Journal of Universal Studies FARMASAINKES PCJN Pharmaceutical and Clinical Journal of Nusantara Usada Nusantara: Jurnal Kesehatan Tradisional Jurnal Ilmu Kesehatan dan Gizi Journal of Pharmaceutical and Sciences. JK Jurnal Kesehatan Medic Nutricia : Jurnal Ilmu Kesehatan Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara

Anny Sartika Daulay

Department Of Pharmacy, Universitas Muslim Nusantara Al Washliyah

Author-ID : 3802192

Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Transportation Veterinary Other

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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN PETAI GAJAH (Parkia speciosa Hassk) di DAERAH KUTACANE, DENGAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazil) Makhfirah; Ridwanto; Fatur Rahman; Anny Sartika Daulay
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 2 No. 2 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Antioksidan dapat menghentikan perkembangan reaksi oksidasi dengan mencegah pembentukan radikal bebas. Daun petai mengandung senyawa fenolik dan flavonoid yang kaya antioksidan. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan. Ekstrak etanol daun petai gajah, juga untuk mengetahui golongan senyawa dalam daun Petai Gajah. Penelitian ini bersifat deskriftif, ekstrak etanol daun petai gajah diperoleh dengan cara maserasi adapun pengujian yang dilakukan meliputi pengujian kadar air, kadar sari laraut dalam air, kadar sari larut dalam etanol, kadar abu, kadar abu tidak larut asam, pengujian skrining fitokimia dan pengujian aktivitas antioksidan. Hasil karakterisasi serbuk simplisia daun Petai gajah diperoleh kadar air 8%, kadar sari yang larut dalam air 12,0%, kadar sari larut dalam etanol 5,4%, kadar abu total 10,7%, dan kadar abu yang tidak larut asam 1,3%. Hasil skrining fitokimia daun petai gajah mengandung senyawa alkaloid, flavonoid, saponin, tanin dan steroid. Hasil pengujian aktivitas antioksidan menunjukan bahwa ekstrak etanol daun petai gajah memiliki nilai IC50 221,9828 µg/ml. Hasil penelitian menunjukkan bahwa ekstrak etanol daun petai gajah memiliki antioksidan lemah.

EVALUASI SEDIAAN HARD CANDY SARI BUAH NANAS (Ananas comosus L.) SEBAGAI NUTRASETIKAL Nurul Salsa Abya Ritonga; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Anny Sartika Daulay
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 2 No. 2 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Permen (candy) memiliki cita rasa manis dan segar yang membuat hampir seluruh masyarakat menyukainya mulai dari anak-anak sampai orang dewasa. Permen menurut jenisnya dua yaitu permen kristalin dan permen non kristalin. Salah satu contoh permen ialah hard candy. Hard candy non kristalin memiliki komposisi sirup glukosa, sukrosa, air, bahan tambahannya flavor, pewarna, zat pengasam. Flavor dari essens atau sari buah. Tujuan penelitian untuk mengetahui jumlah sukrosa yang baik dalam penentuan rasa hard candy dan hasil evaluasi sediaan hard candy sari nanas. Penelitian ini bersifat eksperimental dan meliputi perlakuan buah nanas, produksi sari nanas, produksi hard candy, pengujian organoleptik, pengujian pH, keseragaman bobot, kadar abu, dan kadar air. Berisi parameter uji permen, uji hedonik hasilnya disajikan secara deskriptif. Pembuatan hard candy menggunakan metode open pan. Berdasarkan hasil penelitian, sari nanas diformulasikan dalam sediaan hard candy dengan variasi kadar sukrosa FI (1500 mg), FII (2000 mg) dan FIII (3000 mg) dengan jumlah masing-masing 11,114 mg, 11,614 mg, dan 12,614 mg secara berurut. Bentuk menarik, rasa, kekerasan yang baik, memiliki pH 5 serta memenuhi semua persyaratan uji evaluasi keseragaman bobot dengan koefisien variasi 1% , 0,80%, 1% , kadar air 2,8%, 2,12%, 1,76% , kadar abu 1,7%, 1,1%, 1,02%, hedonik dari suka 1,24, 1,39, 2 . Hasil uji hedonik dari rasa, tekstur, suka menunjukkan F3 formula terbaik yang banyak disukai dengan kadar sukrosa. Kadar sukrosa memberikan pengaruh terhadap tingkat rasa, suka, kekerasan.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN MAHKOTA DEWA (Phaleria macrocarpa (Scheff.) Boerl.) TERHADAP Propionibacterium acnes Syalsabila Putri; Ridwanto; Haris Munandar Nasution; Anny Sartika Daulay
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 2 No. 2 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Daun Mahkota Dewa merupakan tanaman asli indonesia yang berasal dari daerah Papua. Daun mahkota dewa di masyarakat sibolga biasa digunakam untuk mengobati berbagai penyakit secara alamiah. Penelitian ini bertujuan untuk mengetahui golongan senyawa kimia yang terkandung dalam daun mahkota dewa dan untuk mengetahui aktivitas antibakteri ekstrak etanol daun mahkota dewa terhadap bakteri Propionibacterium acnes. Ekstrak simplisia daun mahkota dewa dibuat dengan pelarut etanol 96% dengan metode maserasi. Ekstrak etanol daun mahkota dewa dibuat didalam berbagai konsentrasi yaitu 30%, 40%, 50%. Kontrol positif yang digunakan yaitu Tetraksiklin HCl dan kontrol negatif yang digunakan ialah DMSO. Ada beberapa pengujian yang dilakukan pada daun mahkota dewa yaitu skrining fitokimia, pemeriksaan makroskopik dan mikroskopik, pemeriksaan kadar air, kadar sari larut dalam air, kadar sari larut dalam etanol, kadar abu total, dan kadar abu tidak larut asam. Hasil penelitian yang dilakukan menunjukan bahwa ekstrak etanol daun mahkota dewa mengandung senyawa metabolit sekunder golongan alkaloid, flavonoid, saponin, tanin, steroid/triterpenoid yang memiliki aktivitas antibakteri. Berdasarkan hasil penelitian terhadap antibakteri menunjukkan bahwa ekstrak etanol daun mahkota dewa dapat digunakan untuk menghambat bakteri Propionibacterium acnes.Adapun hasil pada konsentrasi 30% berdiameter 8,03 mm dikategorikan sedang, pada konsentrasi 40% berdiameter 9,26 mm dikategorikan sedang, dan pada konsentrasi 50% berdiameter 9,73 mm dikategorikan sedang.

Antioxidant Activity of Fresh Decinte, Fresh Sari, and Fresh Ethanol Extract of Soursop (Annona muricata L.) Leaves Using DPPH Method Eva Fransiska; Anny Sartika Daulay; Ridwanto Ridwanto; Rafita Yuniarti
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 2 No. 01 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : Nusantara Scientific Medical

Antioxidants are compounds that are able to ward off or reduce free radicals in the body so that they can prevent several diseases. Soursop leaves (Annona muricata L.) are used as a traditional herbal medicine to prevent or treat cancer, as well as a natural antioxidant, which is usually used by people by boiling it. The purpose of this study was to look at the phytochemical screening by comparing fresh boiled water, fresh juice, and a fresh extract of soursop leaves, as well as test the antioxidant activity with the addition of DPPH (1,1-diphenyl-2-picrylhydrazyl) and measured using a UV-Vis spectrophotometer at 516 nm. The results of the soursop leaf phytochemical screening showed that there were groups of chemical compounds such as flavonoids, glycosides, tannins, and saponins. The results of testing the antioxidant activity by looking at the maximum wavelength of DPPH, using a UV-Vis spectrophotometer, obtained IC50 values for fresh juice of 770.067 µg/mL, fresh decoction of 1,022.8422 µg/mL, and ethanol extract of 299.733 µg/mL. Based on the results of the study, it was shown that the ethanol extract had stronger antioxidant activity than a fresh decoction and the fresh juice of soursop leaves.

Penetapan Kadar Vitamin C dalam Sari Buah Nanas (Ananas comosus L. MERR) dengan Metode Spektrofotometri UV Maya Syafira; Anny Sartika Daulay; Ridwanto Ridwanto; Haris Munandar Nasution
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.345

Pineapple or which has the Latin name Ananas Comosus L. MERR has two main ingredients, namely vitamin C and manganese. Vitamin C is very important for the growth and development of the immune system and can help the absorption of iron from food, meanwhile manganese is a natural mineral that has antioxidant properties or can ward off evil compounds in the body and help increase the body's immunity to avoid the Covid-19 disease outbreak.. Therefore, researchers are interested in researching pineapple juice, because what people consume every day is pineapple juice. The aim of this research was to determine the levels of vitamin C in pineapple juice (Ananas comosus L. MERR) and whether the vitamin C content in pineapple juice (Ananas comosus L. MERR) can meet daily nutritional adequacy rates. This research method uses quantitative methods. Where is the relationship between the independent variable and the dependent variable. The independent variable is pineapple filtrate and the dependent variable is vitamin C content. The parameters of this research are vitamin C levels using the UV Spectrophotometry method. The conclusion of this study shows that the results of the examination of pineapple juice levels are 54.6816 21.6678 mcg/g, and the vitamin C content in pineapple juice can meet the daily nutritional adequacy figure, namely 33 mg to 76 mg.

Penentuan Kadar Ketoprofen Generik Dan Nama Dagang Dengan Metode Spektrofotometri-UV Rahmi Ayusasmita Gultom; Anny Sartika Daulay
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1504

Ketoprofen is a non-steroidal anti-inflammatory drug that is used to reduce pain due to inflammation in various rheumatic conditions and degenerative disorders of the skeletal muscle system. In the manufacture of drugs, the examination of the levels of active substances is a requirement that must be met to ensure the quality of the drug. One of the quality requirements is that the content contained must meet the level requirements listed in the Indonesian Pharmacopoeia. The purpose of this study was to determine whether the levels of generic and trade name ketoprofen tablets on the market meet the requirements of the Indonesian Pharmacopoeia levels.This research is descriptive using UV-spectrophotometric method, with 0.1NN NaOH as solvent. The samples used in this study were 4 generic ketoprofen tablets and trade names. The test parameters of this research include Preparation of Standard Parent Solution I (LIB I), Preparation of Solution (LIB II). Determination of maximum wavelength, Determination of linearity of the Calibration Curve and Determination of Ketoprofen levels in tablet preparations. From the test results on samples obtained generic ketoprofen tablets (PT. Hexpharm jaya) of 103.70% ± 0.4280%, ketoprofen tablets with the trade name Kaltropen (PT. Kalbe Farma) of 106.38% ± 0.4879%, tablets Generic ketoprofen (PT. Bernofarm) 102.10%±1.9450%, and generic ketoprofen tablets (PT.Novell) 100.22%±0.8754%. All tablets found met the requirements for the general content, namely the content of the active substance was not less than 99% and not more than 110% of the amount stated on the label.

Aplikasi Metode Spektrofotometri-UV Pada Penentuan Kadar Cetirizine Tablet Generik Dan Nama Dagang Mayang Sari Ritonga; Anny Sartika Daulay
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 1 No. 2 (2023): Juli: USADA NUSANTARA
Publisher : Sekolah Tinggi Agama Buddha Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v1i2.290

Cetirizine is a very strong and very specific antihistamine, cetirizine is also used as a strong and effective drug in treating allergic conjunctivitis such as eye inflammation, skin allergies, respiratory infections and other allergic reactions. Rhinitis is an inflammation of the nose when the immune system reacts to airborne allergens. The purpose of this study was to determine the differences in the levels of cetirizine in generic and trade name tablets. This research is descriptive by using ultraviolet spectrophotometric method. The samples used in this study were 4 tablets of cetirizine, 0.1 N hydrochloride as a solvent and a wavelength of 231 nm. From the test results on the samples, the cetirizine levels in the four samples were Ce (96.43%), Sahado (99.65%), Ryv (104.45%), and Oz (101.330%). The results showed that the level of cetirizine in the tablet preparation met the requirements of the Indonesian Pharmacopoeia Edition IV 2014 which was not less than 90% and not more than 110% of the amount stated on the label.

Penentuan Kadar Meloksikam Sediaan Tablet Dari Berbagai Apotek Yang Terdapat Di Rantau Prapat Secara Spektrofotometri – UV Risma Fauziah Pasaribu; Anny Sartika Daulay; Ridwanto Ridwanto; Rafita Yuniarti
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 1 No. 2 (2023): Juli: USADA NUSANTARA
Publisher : Sekolah Tinggi Agama Buddha Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v1i2.329

Meloxicam is a non-steroidal anti-inflammatory drug that can relieve arthritis symptoms, such as inflammation, swelling, and muscle stiffness and pain, by acting as an inhibitor of enzymes that produce prostaglandins. In the Indonesian Pharmacopoeia Edition V (2014), the determination of sugar tablet content was carried out using high performance liquid chromatography. This method is expensive compared to the spectrophotometric method. The purpose of this research is to find an alternative method that is simple and inexpensive but provides good accuracy. This research was descriptive in nature using spectrophotometry-UV method, with 0.1 N NaOH Methanol as a solvent. The samples used in this study were 4 generic meloxicam tablets. The test parameters of this research included the preparation of Standard Mother Solution I (LIB I). Maximum wavelength, Linearity Protection of the Calibration Curve and Determination of the Concentration of Meloxicam in Tablet Preparations. From the results of testing the samples, generic meloxicam tablets were taken from PT. (Dankos pharma) 102.47 ± 0.9868%; generic meloxicam tablets (PT. Etercon Pharma) 98.05 ± 1.0930%; generic meloxicam tablets (PT. Mahakam Beta Farma) 99.79 ± 1.046%; generic tablets (Triman) 101.21 ± 2.4345%. All the tablets specified meet the general strength requirements, that is, the active ingredient content is not less than 90% and not more than 110% of the amount stated on the label.

PERBANDINGAN KADAR PROTEIN PADA KUNING DAN PUTIH TELUR BEBEK REBUS MENGGUNAKAN METODE KJELDAHL DAN SPEKTROFOTOMETRI VISIBLE M. Naufal Rifqi; Daulay, Anny Sartika; Ridwanto; Rafita Yuniarti
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 4 No. 1 (2024): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v4i1.3350

Pendahuluan: Salah satu telur unggas yang banyak dikonsumsi masyarakat adalah telur bebek Telur merupakan sumber protein hewani dan lauk pauk yang mudah didapat, murah, dan penuh nutrisi. Telur memberikan nutrisi lengkap yang diperlukan untuk pertumbuhan sel. Telur juga menyediakan semua asam amino penting bagi manusia, yang membuatnya menjadi sumber protein berkualitas tinggi. Tujuan: Tujuan Penelitian ini adalah untuk mengetahui dan membandingan kadar protein dari kuning dan putih telur bebek rebus menggunakan metode kjeldahl dan spektrofotometri visible. Metode: Metode penelitian yang digunakan untuk mengukur kadar protein kuning dan putih telur bebek rebus menggunakan metode Kjeldahl dan spektrofotometri visible. Metode Kjeldahl meliputi destruksi, destilasi, dan titrasi, sedangkan metode spektrofotometri tampak meliputi pembuatan larutan biuret, penentuan panjang gelombang maksimum, pembuatan kurva standar, dan penentuan kandungan protein sampel. Hasil: Hasil penelitian didapat kadar protein pada telur rebus dengan metode kjeldahl yaitu kuning telur bebek rebus sebesar 9,5363% dan putih telur bebek rebus sebesar 11,6497%. Dengan metode spektrofotometri visible yaitu kuning telur bebek rebus sebesar 8,4794% dan putih telur bebek rebus sebesar 8,64375%. Terdapat perbedaan nyata kadar protein antara metode kjeldahl dengan spektrofotometri visible dengan hasil SPSS nilai Sig. 0,000 < 0,05.

Penentuan Kadar Alkaloid Total Ektstrak Akar Bajakah (Spatholobus Littoralis Hassk) dengan Metode Spektofotometri Uv-Vis Hanifah, Nur; Daulay, Anny Sartika; Rahman, Fatur; Nasution, Haris Munandar
Journal of Pharmaceutical and Health Research Vol 5 No 1 (2024): February 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i1.4788

The Bajakah tampala tree (Spatholobus littoral hassk) is a native plant from the interior of the forests in Kalimantan, especially Central Kalimantan. This plant is a plant that stretches or grows and grows abundantly in the interior of the forest. The Bajakah plant is known to the people of Kalimantan as a medicinal plant and can cure various diseases, including diarrhea, rheumatism, and cancer. The aim of this research was to determine the alkaloid content of bajakah root extract in various concentrations. The research method was carried out experimentally, with the independent variable being an ethanol extract of bajakah roots with concentrations of 50, 70, and 96%. Meanwhile, the dependent variables are the characteristics of simplicia, the secondary metabolite content of Bajakah root ethanol extract, and the determination of the total alkaloid content of Bajakah root extract. Bajakah root simplicia extract is made with 96, 70, and 50% ethanol solvents. The parameters used in this study include water content, total ash content, acid insoluble ash content, water soluble extract content, ethanol soluble extract content, and secondary metabolite content, including alkaloids, tannins, flavonoids, saponins, steroids, and terpenoids, by conducting phytochemical screening. , making a standard caffeine solution, determining the maximum wavelength of caffeine, measuring the caffeine calibration curve, and determining the total alkaloid content of Bajakah root extract. The results of the phytochemical screening showed that Bajakah root was positive for containing alkaloid compounds, saponins, tannins, flavonoids, steroids, and terpenoids. And the results obtained from Bajakah root plants obtained from Central Kalimantan were a 96% ethanol concentration of 1.66797 ± 0.7088 mg/gram, a 70% ethanol concentration of 1.6679 ± 0.1124 mg/gram, and a 50% ethanol concentration of 0.46981 ± 1.0656 mg/gram

Co-Authors Akbar, Windi Hari Ali Djamhuri Alistraja Dison Silalahi Alviana, Liya Anugrah, Bayu Asep Trizaldi Asparyzha, Rhyzha Azri, Atika Cici Andriani Daeng Elysa Putri Mambang Dalimunnthe, Gabena Indrayani Dalimunthe, Gabena Indriyani Dikki Miswanda Dina Agustia Parlin Dina Suciati Saragih Eva Fransiska Fadillah, Nike Fathur Rahman Fatur Rahman fatur Rahman, fatur Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Hafizha, Putri Harahap, Siti Salimah Haris Munandar Nasution Hasanah, Qori Hasrul Abdi Hasibuan Hindri Syahputri Ihsan Fadhilah Leni Handayani Lubis, Minda Sari M. Naufal Rifqi M. Pandapotan Nasution Makhfirah Manik, Umi Chairani Mardhatillah, Wulan Maya Syafira Mayang Sari Ritonga Merani Phaustina Lumban Gaol Miranza, Nona Muhammad Amin Nasution Muhammad Hizbullah Muhammad Wahyudi Munthe, Ariska Nabilla, Alfira nasution, Alfina Tri Utami Nasution, Nur Sahadah Nia Novranda Pertiwi Nst, Haris Munandar Nur Hanifah Nur'ain Harahap Nurhayati Nurhayati Nurul Salsa Abya Ritonga Pasaribu, Mesi Wilia Afrima Pasaribu, Mesi Willia Afrima Putri Intan Sari Putri Theresia Harianja Rafita Yuniarti Rahmadani Rahmadani Rahmasari, Siti Rahmi Ayusasmita Gultom Retno Sekarini Rezky , Deswita Ina Ricky Andi Syahputra Ridwanto Ridwanto Ridwanto Rika Yuliana, Rika Risma Fauziah Pasaribu Rizki, Rahmad Robiatun Rambe Rosaldi, Hikmah Sagita Marina Simatupang Sandika, M Teguh Sasnita, Merida Sekarini, Retno Siagian , Anggi Yani Sinaga, Novita Yulianti Sri Murni Sri Wahyuni Supiyani, Supiyani Syahfitri , Adelya Syahputra, Ricky Andi Syalsabila Putri Tuzzahra, Safira Yayuk Putri Rahayu Yayuk Putri Rahayu Yuniarti , Rafita Yuniarti, Rafita Zulmai Rani

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