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Anny Sartika Daulay
Universitas Muslim Nusantara Al Washliyah, Medan
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Penetapan kadar flavonoid total ekstrak kayu raru (Cotylelobium lanceolatum Craib) berdasarkan perbedaan konsentrasi etanol dengan metode spektrofotometri Uv-Vis Elma Natasya; Anny Sartika Daulay; Ridwanto Ridwanto; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.305

Abstract

The utilization of traditional medicinal plants for healing is the oldest form of medicine in the world. One of the plants that have many benefits and contain secondary metabolite compounds is raru bark (Cotylelobium lanceolatum Craib), used as a traditional medicine for diseases such as malaria, diarrhea, and diabetes. This study aims to determine what groups of compounds are contained in raru bark extract and the value of total flavonoid levels contained in raru bark extract in differences in ethanol concentrations (96%, 70%, 50%). The stages of this research include processing plant materials, making ethanol extracts of raru bark extract, characterization examination, phytochemical screening, and determining the total flavonoid content of raru bark ethanol extract. The section of raru bark was made by maceration method using 96%, 70%, and 50% ethanol. Then, the extract obtained was concentrated with a rotary evaporator, and the determination of total flavonoid content was carried out based on differences in ethanol concentration using the UV-Vis spectrophotometric method. The results showed that the ethanol extract of raru bark contained alkaloids, flavonoids, saponins, tannins, and steroid compounds. Determination of total flavonoid content by determining the maximum wavelength of quinine and calculating entire flavonoid content by UV-Vis spectrophotometric method. The results of the decision of complete flavonoid content of raru bark ethanol extract at 96% concentration are 1.9915 ± 0.0139 mg QE/g, 70% is 1.12492 ± 0.01532 mg QE/g, and for 50% is 0.95197 ± 0.01516 mg QE/g. So, the best ethanol concentration to produce flavonoid levels is 96%, which is higher than other ethanol concentrations.
Penetapan kadar fenolik total ekstrak kayu raru (Cotylelobium lanceolatum Craib) berdasarkan perbedaan konsentrasi etanol dengan metode spektrofotometri UV-Vis Lastri Afni; Anny Sartika Daulay; Ridwanto Ridwanto; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.306

Abstract

Many Indonesian people use or use plants as traditional medicine; one plant that has many benefits is raru bark (Cotylelobium lanceolatum Craib), which is used as a traditional medicine in various diseases such as diarrhea, malaria, and diabetes. This study aims to find out what classes of compounds are found in raru bark extract and to determine the value of total phenolic levels contained in raru bark extract in various concentrations (96%, 70%, 50%). The stages of this research include processing plant materials, making raru bark ethanol extract, characterization examination, phytochemical screening, and determining total phenolic levels of raru bark extract based on differences in ethanol concentration by UV-Vis spectrophotometry method. The results showed that raru bark ethanol extract contains compounds, flavonoids, tannins, saponins, steroids, and phenolics. Determination of total phenolic content by determining the maximum wavelength of gallic acid and calculation of entire phenolic content by UV-Vis spectrophotometry method. Results of selecting the whole phenolic content of raru bark ethanol extract at a concentration of 96%; 28,6544±0,1548 mgGAE/g, 70%; 23,9682±0,1270 mgGAE/g, 50%; 20,5825±0,1993 mgGAE/g, then the phenolic content that best produces total phenolic levels is raru bark ethanol extract (Cotylelobium lanceolatum Craib) concentration of 96%.
Prevalensi bakteri Salmonella sp. pada daging ayam potong di pasar tradisional, pasar modern, dan merek terkenal di kota Medan. Lulu Ilma Khoirun Nissa; Yayuk Putri Rahayu; D. Elysa Putri Mambang; Anny Sartika Daulay
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.330

Abstract

Chicken is a source of animal protein for humans. Chicken meat generally contains unsaturated fat; chicken meat also has a compact meat texture and simple protein, so it is easily digested. However, chicken meat can also be contaminated with Salmonella sp. Pathogenic bacteria can cause typhus or typhoid fever, caused by traders' lack of cleanliness and hygiene or their environment. Research was conducted to identify the presence of Salmonella sp. Pathogenic bacteria and analysing the value of Salmonella sp. Pathogenic bacteria contamination that met the Indonesian National Standard (SNI), namely harmful/25g in chicken meat from traditional markets, modern markets, and well-known brands in Medan City, and to determine the prevalence value of Salmonella sp. Bacteria. The method of research uses Total Plate Count (TPC). An identification test is first carried out to calculate and determine the presence of bacteria in a test sample for the existence of Salmonella sp. Pathogenic bacteria and choose the total value of contaminants using a Total Plate Count (TPC), then identify using a gram staining test. These biochemical tests include the indole test, MRVP test, citrate test, urea test, TSIA test, and LIA test. Then, the last one determines the Prevalence value of Salmonella sp. Bacteria. The results showed that the samples of traditional market and modern market chicken meat were positive for the presence of the pathogenic bacteria Salmonella sp. by obtaining Subgenus Salmonella Typhimurium on N2H8 sample code APTL and APTB, N3H15 sample code APTL, APTB, APMI and obtaining Subgenus Salmonella Thypi on N3H15 sample code APMS and the contamination value of the pathogenic bacteria Salmonella sp. Exceeds the threshold and does not meet the Indonesian National Standard (SNI), namely negative/25g. The prevalence value obtained by the pathogenic bacteria Salmonella sp. in broiler meat at Traditional Markets, Modern Markets, and well-known brands is 75%, 50%, and 0%, respectively.
OPTIMASI PEMBUATAN TEPUNG TALAS TERMODIFIKASI (Modified Taro Flour) DENGAN FERMENTASI Lactobacillus casei BERDASARKAN KADAR PROTEIN Imelda Natasia Br S Meliala; Anny Sartika Daulay; Ridwanto Ridwanto; Haris Munandar Nasution
Jurnal Farmasi Klinik dan Sains Vol 3, No 1 (2023): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v3i1.1110

Abstract

Ketergantungan penggunaan tepung terigu dapat dikurangi dengan menggunakan sumber karbohidrat lainnya seperti talas yang merupakan pangan lokal. Lactobacillus casei adalah salah satu spesies Bakteri Asam Laktat yang dapat menggunakan selobiosa sebagai sumber nutrisinya. Diperkirakan Lactobacillus casei dapat mendegresi sel umbi talas agar meningkatkan kadar protein talas. Diantara faktor yang dapat mempengaruhi kondisi fermentasi untuk menghasilkan tepung termodifikasi yang optimal adalah waktu fermentasi. Penelitian ini bertujuan untuk mengetahui pengaruh optimasi fermentasi umbi talas terhadap organoeleptis dan kadar protein pada tepung talas termodifikasi. Penelitian ini menggunakan metode eksperimental dengan dua optimasi waktu fermentasi yaitu fermentasi 48 jam dan fermentasi 72 jam dan uji karakterisasi yaitu uji organoleptis, uji kadar air, uji kadar abu dan uji kadar protein. Hasil penelitian ini menunjukkan organoleptis tepung mocaf, tepung talas, tepung talas termodifikasi berwarna coklat dan putih kecoklatan, bau sedikit asam dan tekstur yang halus. Kadar protein mocaf yaitu 2,17, tepung talas 2,33%, tepung talas termodifikasi 48 jam 3,16%, tepung talas termodifikasi 72 jam 3,53%. Kadar air tepung mocaf 11,31%, tepung talas 8,67%, tepung talas termodifikasi sebesar 10,81%. Kadar abu tepung mocaf 1,13%, tepung talas 2,73%, tepung talas termodifikasi 1,82%. Hasil yang diperoleh menunjukkan bahwa  fermentasi 72 jam merupakan hasil yang optimal.
Peran Bioteknologi Dalam Keterkaitan Berbagai Aspek Bidang Ilmu Pengetahuan Serta Mewujudkan Inovasi dan Kreatifitas di Kalangan Mahasiswa Universitas Harapan Medan Sri Wahyuni; Nomi Noviani; Anny Sartika; Dian Habibie; Leni Handayani
Jurnal Pengabdian West Science Vol 3 No 01 (2024): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v3i01.917

Abstract

Bioteknologi adalah ilmu pengetahuan yang mempelajari tentang mahluk hidup baik mikroorganisme maupun makroorganisme, perkembangan, pemanfaatan serta keterkaitan bidang ilmu tersebut terhadap ilmu lainnya. Tujuan dari Pengabdian Kepada Masyarakat ini antara lain 1. Untuk meningkatkan pengetahuan terhadap Konsep Dasar bidang Bioteknologi, 2. Mengetahui Pemanfaatan Bioteknologi dalam Kehidupan Sehari-hari 3. Mengetahui keterkaitan Bidang Bioteknologi dengan ilmu –Ilmu yang lain. Metode yang digunakan dalam pengabdian ini dengan menggunakan metode ceramah dan diskusi yaitu dengan memaparkan beberapa materi mengenai Bioteknologi melalui media aplikasi slide persentase. Metode yang kedua yaitu dengan menggunakan metode aplikasi yaitu menjelaskan dan mempraktikkan bentuk Bioteknologi baik modern maupun sederhana. Dari hasil kegiatan PKM diperoleh persentase mitra dari jumlah 100 orang menunjukkan sebanyak 19% (81 orang) responden dari mitra menjawab peran Bioteknologi sebagai bagian konsep dasar pengetahuan dan keterkaitan dengan pengetahuan lainnya dapat dengan mudah dipahami. 20% (80 orang) menyatakan keterkaitan dengan berbagai contoh serta aplikasi Bioteknologi dan penjelasan dari narasumber juga disampaikan dengan baik. Dari aspek berbagai bidang ilmu 20% (80 orang) dapat disampaikan dengan jelas, kemudian 20% (80 orang) peningkatan pengetahuan mitra terhadap pengetahuan baru terhadap bioteknologi dan persentase 21% (79 orang) siswa mengatakan peran manusia dalam bidang Bioteknologi dan sebagai mahluk ciptaan semakin dipahami dalam menjalankan kehidupan. Dari kesimpulan yang diperoleh bahwa rata-rata kegiatan pengenalan Bioteknologi ini sangat bermanfaat serta menambah pengetahuan jika dikaitkan dengan hal yang positif untuk kemajuan pengetahuan, mahluk social serta lingkungan sekitar.
Penentuan Kadar Ketoprofen Generik Dan Nama Dagang Dengan Metode Spektrofotometri-UV Rahmi Ayusasmita Gultom; Anny Sartika Daulay
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1504

Abstract

Ketoprofen is a non-steroidal anti-inflammatory drug that is used to reduce pain due to inflammation in various rheumatic conditions and degenerative disorders of the skeletal muscle system. In the manufacture of drugs, the examination of the levels of active substances is a requirement that must be met to ensure the quality of the drug. One of the quality requirements is that the content contained must meet the level requirements listed in the Indonesian Pharmacopoeia. The purpose of this study was to determine whether the levels of generic and trade name ketoprofen tablets on the market meet the requirements of the Indonesian Pharmacopoeia levels.This research is descriptive using UV-spectrophotometric method, with 0.1NN NaOH as solvent. The samples used in this study were 4 generic ketoprofen tablets and trade names. The test parameters of this research include Preparation of Standard Parent Solution I (LIB I), Preparation of Solution (LIB II). Determination of maximum wavelength, Determination of linearity of the Calibration Curve and Determination of Ketoprofen levels in tablet preparations. From the test results on samples obtained generic ketoprofen tablets (PT. Hexpharm jaya) of 103.70% ± 0.4280%, ketoprofen tablets with the trade name Kaltropen (PT. Kalbe Farma) of 106.38% ± 0.4879%, tablets Generic ketoprofen (PT. Bernofarm) 102.10%±1.9450%, and generic ketoprofen tablets (PT.Novell) 100.22%±0.8754%. All tablets found met the requirements for the general content, namely the content of the active substance was not less than 99% and not more than 110% of the amount stated on the label.
Aplikasi Metode Spektrofotometri-UV Pada Penentuan Kadar Cetirizine Tablet Generik Dan Nama Dagang Mayang Sari Ritonga; Anny Sartika Daulay
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 1 No. 2 (2023): Juli: USADA NUSANTARA
Publisher : Institut Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v1i2.290

Abstract

Cetirizine is a very strong and very specific antihistamine, cetirizine is also used as a strong and effective drug in treating allergic conjunctivitis such as eye inflammation, skin allergies, respiratory infections and other allergic reactions. Rhinitis is an inflammation of the nose when the immune system reacts to airborne allergens. The purpose of this study was to determine the differences in the levels of cetirizine in generic and trade name tablets. This research is descriptive by using ultraviolet spectrophotometric method. The samples used in this study were 4 tablets of cetirizine, 0.1 N hydrochloride as a solvent and a wavelength of 231 nm. From the test results on the samples, the cetirizine levels in the four samples were Ce (96.43%), Sahado (99.65%), Ryv (104.45%), and Oz (101.330%). The results showed that the level of cetirizine in the tablet preparation met the requirements of the Indonesian Pharmacopoeia Edition IV 2014 which was not less than 90% and not more than 110% of the amount stated on the label.
Penentuan Kadar Meloksikam Sediaan Tablet Dari Berbagai Apotek Yang Terdapat Di Rantau Prapat Secara Spektrofotometri – UV Risma Fauziah Pasaribu; Anny Sartika Daulay; Ridwanto Ridwanto; Rafita Yuniarti
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 1 No. 2 (2023): Juli: USADA NUSANTARA
Publisher : Institut Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v1i2.329

Abstract

Meloxicam is a non-steroidal anti-inflammatory drug that can relieve arthritis symptoms, such as inflammation, swelling, and muscle stiffness and pain, by acting as an inhibitor of enzymes that produce prostaglandins. In the Indonesian Pharmacopoeia Edition V (2014), the determination of sugar tablet content was carried out using high performance liquid chromatography. This method is expensive compared to the spectrophotometric method. The purpose of this research is to find an alternative method that is simple and inexpensive but provides good accuracy. This research was descriptive in nature using spectrophotometry-UV method, with 0.1 N NaOH Methanol as a solvent. The samples used in this study were 4 generic meloxicam tablets. The test parameters of this research included the preparation of Standard Mother Solution I (LIB I). Maximum wavelength, Linearity Protection of the Calibration Curve and Determination of the Concentration of Meloxicam in Tablet Preparations. From the results of testing the samples, generic meloxicam tablets were taken from PT. (Dankos pharma) 102.47 ± 0.9868%; generic meloxicam tablets (PT. Etercon Pharma) 98.05 ± 1.0930%; generic meloxicam tablets (PT. Mahakam Beta Farma) 99.79 ± 1.046%; generic tablets (Triman) 101.21 ± 2.4345%. All the tablets specified meet the general strength requirements, that is, the active ingredient content is not less than 90% and not more than 110% of the amount stated on the label.
PERBANDINGAN KADAR PROTEIN PADA KUNING DAN PUTIH TELUR BEBEK REBUS MENGGUNAKAN METODE KJELDAHL DAN SPEKTROFOTOMETRI VISIBLE M. Naufal Rifqi; Daulay, Anny Sartika; Ridwanto; Rafita Yuniarti
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 4 No. 1 (2024): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v4i1.3350

Abstract

Pendahuluan: Salah satu telur unggas yang banyak dikonsumsi masyarakat adalah telur bebek Telur merupakan sumber protein hewani dan lauk pauk yang mudah didapat, murah, dan penuh nutrisi. Telur memberikan nutrisi lengkap yang diperlukan untuk pertumbuhan sel. Telur juga menyediakan semua asam amino penting bagi manusia, yang membuatnya menjadi sumber protein berkualitas tinggi. Tujuan: Tujuan Penelitian ini adalah untuk mengetahui dan membandingan kadar protein dari kuning dan putih telur bebek rebus menggunakan metode kjeldahl dan spektrofotometri visible. Metode: Metode penelitian yang digunakan untuk mengukur kadar protein kuning dan putih telur bebek rebus menggunakan metode Kjeldahl dan spektrofotometri visible. Metode Kjeldahl meliputi destruksi, destilasi, dan titrasi, sedangkan metode spektrofotometri tampak meliputi pembuatan larutan biuret, penentuan panjang gelombang maksimum, pembuatan kurva standar, dan penentuan kandungan protein sampel. Hasil: Hasil penelitian didapat kadar protein pada telur rebus dengan metode kjeldahl yaitu kuning telur bebek rebus sebesar 9,5363% dan putih telur bebek rebus sebesar 11,6497%. Dengan metode spektrofotometri visible yaitu kuning telur bebek rebus sebesar 8,4794% dan putih telur bebek rebus sebesar 8,64375%. Terdapat perbedaan nyata kadar protein antara metode kjeldahl dengan spektrofotometri visible dengan hasil SPSS nilai Sig. 0,000 < 0,05.
Penentuan Kadar Alkaloid Total Ektstrak Akar Bajakah (Spatholobus Littoralis Hassk) dengan Metode Spektofotometri Uv-Vis Hanifah, Nur; Daulay, Anny Sartika; Rahman, Fatur; Nasution, Haris Munandar
Journal of Pharmaceutical and Health Research Vol 5 No 1 (2024): February 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i1.4788

Abstract

The Bajakah tampala tree (Spatholobus littoral hassk) is a native plant from the interior of the forests in Kalimantan, especially Central Kalimantan. This plant is a plant that stretches or grows and grows abundantly in the interior of the forest. The Bajakah plant is known to the people of Kalimantan as a medicinal plant and can cure various diseases, including diarrhea, rheumatism, and cancer. The aim of this research was to determine the alkaloid content of bajakah root extract in various concentrations. The research method was carried out experimentally, with the independent variable being an ethanol extract of bajakah roots with concentrations of 50, 70, and 96%. Meanwhile, the dependent variables are the characteristics of simplicia, the secondary metabolite content of Bajakah root ethanol extract, and the determination of the total alkaloid content of Bajakah root extract. Bajakah root simplicia extract is made with 96, 70, and 50% ethanol solvents. The parameters used in this study include water content, total ash content, acid insoluble ash content, water soluble extract content, ethanol soluble extract content, and secondary metabolite content, including alkaloids, tannins, flavonoids, saponins, steroids, and terpenoids, by conducting phytochemical screening. , making a standard caffeine solution, determining the maximum wavelength of caffeine, measuring the caffeine calibration curve, and determining the total alkaloid content of Bajakah root extract. The results of the phytochemical screening showed that Bajakah root was positive for containing alkaloid compounds, saponins, tannins, flavonoids, steroids, and terpenoids. And the results obtained from Bajakah root plants obtained from Central Kalimantan were a 96% ethanol concentration of 1.66797 ± 0.7088 mg/gram, a 70% ethanol concentration of 1.6679 ± 0.1124 mg/gram, and a 50% ethanol concentration of 0.46981 ± 1.0656 mg/gram
Co-Authors Afrizani, Afrizani Akbar, Windi Hari Ali Djamhuri Alviana, Liya Anugrah, Bayu Asep Trizaldi Asparyzha, Rhyzha Azri, Atika Cici Andriani D. Elysa Putri Mambang Daeng Elysa Putri Mambang Daeng Elysa Putri Mambang Dahnia Ayu Fitria Dalimunnthe, Gabena Indrayani Dalimunthe, Gabena Indriyani Dikki Miswanda Dina Agustia Parlin Dina Suciati Saragih Dinda Sari Utami Eli Handayani Elma Natasya Fadillah, Nike Falah Rambe, Raudhotul Fathur Rahman Fathur Rahman Fatur Rahman fatur Rahman, fatur Fithri Pulungan, Ainil Fitri Mulyani, Fitri FRANSISKA, EVA Gabena Indrayani Dalimunthe H., Fathur Rahman Habibie, Dian Hafizha, Putri Harahap, Siti Salimah Haris Munandar Nasution Haris Munandar Nst Hasanah, Qori Hasrul Abdi Hasibuan Hastri Kholifah Helni Maulida Hindri Syahputri Ihsan Fadhilah Imelda Natasia Br S Meliala Indah Triutami Harahap Irfan Ahmad Dasuki Nasution Lastri Afni Leni Handayani Leni Handayani Lubis, Minda Sari Lulu Ilma Khoirun Nissa M Rayhan Ulmi M. Naufal Rifqi M. Pandapotan Nasution M. Pandapotan Nasution Makhfirah Manik, Umi Chairani Mardhatillah, Wulan Maya Syafira Mayang Sari Ritonga Melati Yulia Kusumastuti Merani Phaustina Lumban Gaol Miranza, Nona Muhammad Amin Nasution Muhammad Hizbullah Muhammad Wahyudi Munthe, Ariska Nabilla, Alfira nasution, Alfina Tri Utami Nasution, Kartika Zsaskia Nasution, Nur Sahadah Nia Novranda Pertiwi Nomi Noviani Nomi Noviani Nur Ainun Nur Hanifah Nur'ain Harahap Nurul Salsa Abya Ritonga Nurul Shaleha Pasaribu, Mesi Wilia Afrima Pasaribu, Mesi Willia Afrima Pulungan, Ainil Fitri Putri Intan Sari Putri Theresia Harianja Rahayu Rahayu Rahmadani Rahmadani Rahmah, Ruhiya Rahmi Ayusasmita Gultom Retno Sekarini Rezky , Deswita Ina Ridwanto Ridwanto Ridwanto Rika Yuliana, Rika Risma Fauziah Pasaribu Rizki, Rahmad Rosaldi, Hikmah Rossa, Aliffa Safrida Safrida Sagita Marina Simatupang Sandika, M Teguh Sarmadansyah Sarmadansyah Sasnita, Merida Sekarini, Retno Selfiani Selfiani Shakila Salwa Shilvia, Fatin Siagian , Anggi Yani Sinaga, Novita Yulianti Siti Rahmasari Sri Murni Sri Wahyuni Supiyani Supiyani Supiyani, Supiyani Syahfitri , Adelya Syahputra, Ricky Andi Syalsabila Putri Syarifah Nadia Tamara Army Tuzzahra, Safira Ulmi, M Rayhan Winda Kesuma Yayuk Putri Rahayu Yayuk Putri Rahayu Yulia Nanda Putri Yuniarti , Rafita Yuniarti, Rafita Ziza Putri Aisyia Fauzi Zulmai Rani