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All Journal JURNAL PENELITIAN SAINTIKA Jurnal Hasil Penelitian Industri Jurnal Surya Medika AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT PREPOTIF : Jurnal Kesehatan Masyarakat Science Midwifery Journal of Pharmaceutical and Health Research International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Chemical Science and Technology Jurnal Kesehatan Tambusai JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal Farmanesia IKA BINA EN PABOLO : PENGABDIAN KEPADA MASYARAKAT Journal of Health and Medical Science International Journal of Health and Pharmaceutical (IJHP) Eduvest - Journal of Universal Studies FARMASAINKES PCJN Pharmaceutical and Clinical Journal of Nusantara Usada Nusantara: Jurnal Kesehatan Tradisional Jurnal Ilmu Kesehatan dan Gizi Journal of Pharmaceutical and Sciences. JK Jurnal Kesehatan Medic Nutricia : Jurnal Ilmu Kesehatan Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara
Anny Sartika Daulay
Department Of Pharmacy, Universitas Muslim Nusantara Al Washliyah
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Determination of Total Flavonoid Levels of Bajakah Wood Extract (Spatholobus Littoralis Hassk) on Various Ethanol Concentrations and Antibacterial Activity Test of Staphylococcus Aureus Rahmasari, Siti; Ridwanto, Ridwanto; daulay, Anny sartika; Nst, Haris Munandar
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50927

Abstract

The bajakah plant is one of the biological plants used in traditional medicine. Bajakah is also a medicinal herbal plant that can be used in all its parts. This plant can be found in the depths of Kalimantan Province, but it has not spread to other regions. There has been no effort to cultivate bajakah because of the lack of understanding of the local population about the use of this plant. This research includes the stages of processing plant materials, making ethanol extracts, characterization examinations, phytochemical screening, and determining total flavonoid levels of ethanol extract of Bajakah wood using the visible spectrophotometry method and antibacterial activity. Bajakah wood extract was made by maceration method using ethanol concentrations of 96%, 70%, and 50%, and the extract obtained was concentrated with a rotary evaporator, then the total flavonoid level was determined using the visible spectrophotometry method and antibacterial activity tests were carried out against Staphylococcus aureus As a positive control using chloramphenicol and negative control using dimethyl sulfoxide. The results were obtained by determining the maximum wavelength of quercetin and operating time, measuring the quercetin calibration curve, and calculating the total flavonoid level using the visible spectrophotometry method. The results obtained in the determination of total flavonoid levels in Bajakah wood ethanol extract at a concentration of 96% were 349.888 ± 4.5022 mg QE/g, at a 70% concentration of 307.137 ± 6.7626 mg QE/g and a 50% concentration of 6.15173 ± 2.9148 mg QE/g.
Formulasi dan Uji SPF Sunscreen Powder dari Nanopartikel Ekstrak Kulit Jeruk Bali (Citrus maxima (Burm) Merr.): Formulation and SPF Testing of Sunscreen Powder from Nanoparticle Extract of Pomelo Peel (Citrus maxima (Burm) Merr.) Azri, Atika; Ridwanto, Ridwanto; Daulay, Anny SArtika; Dalimunthe, Gabena Indriyani
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.9256

Abstract

Radiasi ultraviolet (UV) merupakan salah satu ancaman utama bagi kesehatan kulit yang berkontribusi pada terjadinya penuaan dini, kerusakan DNA, dan peningkatan risiko kanker kulit. Senyawa antioksidan, seperti flavonoid yang banyak ditemukan pada tumbuhan, memiliki kemampuan untuk menetralkan radikal bebas yang dihasilkan akibat paparan sinar UV. Penelitian ini bertujuan untuk menghasilkan potensi ekstrak kulit jeruk bali, yang kaya akan flavonoid, sebagai tabir surya alami. Untuk meningkatkan stabilitas dan homogenitas formulasi, ekstrak kulit jeruk bali dimodifikasi menjadi nanopartikel, yang diharapkan dapat meningkatkan efektivitasnya dalam sediaan tabir surya bubuk. Formulasi sediaan dilakukan dalam empat konsentrasi, yaitu formulasi blanko, F1 (5%), F2 (10%), dan F3 (15%). Evaluasi mutu fisik sediaan meliputi uji organoleptis, homogenitas, derajat halus, daya lekat, derajat keasaman (pH), hedonik/kesukaan, dan Sun Protection Factor (SPF). Hasil penelitian menunjukkan bahwa uji mutu fisik sediaan tabir surya bubuk berbasis ekstrak nanopartikel kulit jeruk bali memenuhi kriteria yang ditetapkan. Ekstrak nanopartikel yang dihasilkan memiliki ukuran 205,2 nm, indeks polidispersitas 0,359, dan zeta potensial -16,0 mV. Nilai SPF dari formulasi tabir surya bubuk berturut-turut adalah 1,617 (minimal), 7,946 (ekstra), 16,554 (ultra), dan 19,072 (ultra), menunjukkan efektivitas perlindungan yang signifikan terhadap sinar UV. Penelitian ini memberikan pengetahuan baru mengenai potensi penggunaan ekstrak tumbuhan sebagai alternatif dalam pengembangan produk tabir surya alami.
Formulasi Sabun Transparan Sari Wortel (Daucus carota L.) Sebagai Pelembab Kulit Miranza, Nona; Yuniarti, Rafita; Lubis , Minda Sari; Daulay, Anny Sartika
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.834

Abstract

Transparent soap is a type of soap that appears clear and attractive, with a finer foam. Carrots are one of the plants that contain compounds that can naturally moisturize the skin. The chemical compounds in carrots that can be used as skin moisturizers are present in high amounts. The aim of this study is to formulate transparent soap using carrot Juice as a skin moisturizer. The transparent soap formulation was made using carrot Juice at concentrations of 4%, 6%, and 8%. The evaluation of the transparent soap formulation included organoleptic testing, moisture content testing, foam height testing, pH testing, irritation testing, and hedonic testing. The results showed that the 8% concentration had the highest moisture content, at 14.45%. The highest foam height measurement was also observed at the 8% concentration, with an average of 8.3. The highest pH level was recorded at 8% concentration, with a value of 9.34. Skin analyzer testing indicated that the highest skin moisture level was achieved at 8% concentration, reaching 48%. The transparent carrot Juice soap met the standards set by the Indonesian National Standard (SNI) in terms of organoleptic properties, moisture content, foam height, pH, skin analyzer results, irritation testing, and hedonic testing. The conclusion of this study is that carrot Juice can be formulated into transparent soap that meets SNI requirements.
Penetapan Kadar Rhodamin B Pada Bumbu Tabur Dengan Metode KLT Dan KCKT Munthe, Ariska; Daulay, Anny Sartika; Ridwanto, Ridwanto; Pulungan , Ainil Fithri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.845

Abstract

Rhodamine B is a colouring substance in the form of green or reddish-purple crystals, which are odourless and in the form of a bright red solution (fluorescent). Rhodamin B is a colouring substance that can only be used in the textile, paint, paper, or clothing industries, so it cannot be added to food. Rhodamine B is often used as a coloring agent in paper and textiles. This substance is the most dangerous; if consumed, it can cause problems with liver function and liver cancer. The stages of this research include a sample solution, making Rhodamin B standard stock solution, and making a mobile phase. Examination of qualitative analysis using thin layer chromatography and determination of Rhodamine B levels in seasoning performance liquid chromatography method. The results of the research showed that in the qualitative examination, there were two samples containing Rhodamin B. Rhodamin B levels were determined by determining the retention time and calculating Rhodamin B levels using the high-performance liquid chromatography method. The result of deciding Rhodamine B levels in the two samples containing Rhodamin B was sample A; 2,8915 mcg/g  ,sampel B ; 19,6702 mcg/g  Mcg/g. Then, the highest levels of Rhodamin B are found in sample B.
Analisis Kadar Protein Pada Beberapa Jenis Susu Tinggi Protein Dengan Metode Kjeldahl dan Spektrofotometri Visible Syahfitri , Adelya; Daulay, Anny Sartika; Ridwanto, Ridwanto; Yuniarti , Rafita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.865

Abstract

Introduction: Protein is an essential nutrient that serves as an energy source and plays a crucial role in tissue formation. Protein deficiency can lead to various health disorders, ranging from hair loss to serious conditions such as death. High-protein milk serves as an ideal protein source as it contains essential amino acids and complete nutrients, though its consumption should be adjusted to individual needs to avoid side effects. Research Objectives: This study aims to: (1) analyze protein content in high-protein milk (Whey, Casein, and Gainer) using the Kjeldahl and Visible Spectrophotometry methods, and (2) verify the consistency between analysis results and protein content claims on product packaging. Research Methods: Analysis was conducted using two methods: the Kjeldahl method as a high-precision standard method and Visible Spectrophotometry using Biuret reagent which is more sensitive. Each sample was analyzed with six repetitions to ensure data accuracy. Samples were selected purposively based on best-selling products. Results: The results showed the highest protein content in Whey (525.87 mg/g with Kjeldahl; 873.75 mg/g with Spectrophotometry), followed by Casein (316.87 mg/g; 720.83 mg/g), and the lowest in Gainer (227.5 mg/g; 570.5 mg/g). This consistent pattern indicates conformity with packaging claims, although there were value differences between the two methods. Conclusion: The findings emphasize the importance of verifying protein content in supplement products to ensure nutritional information accuracy for consumers. The differences between the two analysis methods are presumably due to their different analytical principles. This study contributes to developing accurate protein analysis methods for high-protein milk products.  
Kandungan Vitamin C dan Uji Aktivitas Antioksidan Teh Herbal Kombucha Daun Bidara (Ziziphus mauritiana Lam) Siagian , Anggi Yani; Yuniarti, Rafita; Daulay, Anny Sartika; Pulungan , Ainil Fithri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.880

Abstract

Background: Bidara leaves (Ziziphus mauritiana Lam.) have long been used in traditional medicine due to their bioactive compounds, such as flavonoids, tannins, and vitamin C. Fermenting bidara leaves into kombucha has the potential to enhance antioxidant activity through bioconversion processes carried out by starter microbes (Acetobacter xylinum and Saccharomyces cerevisiae). However, scientific data regarding the vitamin C profile and antioxidant activity of bidara leaf kombucha remain limited. Objective: This study aims to analyze the vitamin C content and antioxidant activity of bidara leaf herbal kombucha, as well as to characterize the quality of the simplisia based on the Indonesian National Standard (SNI) 4324:2014. Methods: This descriptive study involved: (1) preparation of bidara leaf simplisia, (2) 12-day kombucha fermentation, (3) phytochemical screening, (4) determination of vitamin C content using UV-Vis spectrophotometry (λ = 266 nm), and (5) antioxidant activity assay using the DPPH method (λ = 517 nm). Results: The bidara leaf simplisia met the SNI quality standards, with a moisture content of 5.33% and a total ash content of 6.73%. Phytochemical screening identified the presence of flavonoids, saponins, tannins, glycosides, steroids/triterpenoids, and alkaloids. The vitamin C content of the kombucha was 0.009 mg/g, while the IC₅₀ value for antioxidant activity was 621.2158 µg/mL, which falls into the weak category. Conclusion: Bidara leaf kombucha contains bioactive compounds and vitamin C, with weak antioxidant activity. Fermentation increases antioxidant activity compared to non-fermented bidara tea infusion (IC₅₀ = 1129.0069 µg/mL), although it remains lower than that of pure vitamin C (IC₅₀ = 3.0710 µg/mL).
Determination of Total Alkaloid Content of Raru (Cotylelobium lanceolatum Craib) Bark Extract Using UV-ViS Spectrophotometry Method andriani, cici; Daulay, Anny Sartika; Ridwanto, Ridwanto; Nasution, Haris Munandar
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i1.10

Abstract

The raru plant (Cotylelobium  lanceolatum Craib) comes from the Dipterocarpaceae family. Raru bark is usually added to the wine to enhance the taste of the wine. raru bark has antidiabetic compounds as a lowering of sugar levels in the blood. The purpose of this study was to determine the alkaloids in the Raru plant (Cotylelobium   lanceolatum  Craib) and to determine the total alkaloid content found in the Raru plant (Cotylelobium  lanceolatum  Craib). The extraction method used is the maceration extraction method using methanol solvent with various concentrations which is then evaporated with a rotary evaporator. Whereas the quantitative test was carried out by means of the viscous extract obtained by adding 2 mL of Phosphate buffer with a pH of 4.7, 2 mL of bromocresol green (BCG), and measured at a wavelength of 272.705 nm. The yield of the extract from a concentration of 95% was 23.0779%, a concentration of 70% was 21.2144%, a concentration of 50% was 20.3274%. The correlation equation obtained from the caffeine curve is y = 0.0508X + 0.008 and the value of r = 0.999, and the levels of alkaloids with different extract concentrations. Actual alkaloid content in raru bark methanol extract 95% was 14.9094 ± 0.3697 mg/g, actual alkaloid content in raru bark methanol extract 70% was 10.0472 ± 0.4594 mg/g, actual alkaloid content in extract 50% raru bark methanol was 6.6260 ± 0.803.
Analysis of Sodium Benzoate Content in the Market Soft Beverages Using Uv-Vis Spectrophotometry Method Akbar, Windi Hari; Pulungan, Ainil Fithri; Ridwanto, Ridwanto; Daulay, Anny Sartika
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i1.15

Abstract

Sodium benzoate is one of the preservatives that are permitted to be used in food and beverages. Research has been carried out with the aim of knowing that carbonated drinks contain the preservative sodium benzoate, knowing the amount of sodium benzoate in soft drinks and to find out the levels of sodium benzoate in soft drinks fulfilling the maximum usage requirements according to BPOM RI Head Regulation No. 36 of 2013. This study used the uv-vis spectrophotometry method. To determine the preservative content of sodium benzoate, a qualitative test was first carried out on the sample using the color reaction method and esterification test. To determine the levels using a UV-Vis spectrophotometer at a wavelength of 269 nm with ethanol p.a as a solvent. The results of the qualitative test using the color reaction method showed that the three samples of soft drinks positively contained the preservative sodium benzoate. To validate this, an esterification test was carried out on the three samples and they produced the smell of Ambon bananas which proved that the three samples positively contained sodium benzoate. For the quantitative test using the Uv-Vis spectrophotometry method at a wavelength of 269 nm using ethanol p.a as a solvent. The results of the analysis showed that the preservative content of sodium benzoate which was calculated for each sample was for a soft drink sample a: 244.93 ± 19.9349 mg/kg. Soft drinks b: 65.3 ± 0 mg/kg, soft drinks. Soft drinks c: 78.6 ± 13.1291 mg/kg. Based on these results, it can be concluded that the levels of sodium benzoate in samples A, B, and C met the standard requirements for maximum usage limits, namely not more than 600 mg/kg.
Effect of Extraction Method on Yellow Wood Rendement and Phenolic Content (Arcangelisia flava (L.) Merr) UV-Vis Spectrophotometry Extract of Ethanol Sasnita, Merida; Daulay, Anny Sartika; Ridwanto, Ridwanto; Nasution, Haris Munandar
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i1.25

Abstract

Indonesia is a country rich in biodiversity. With the wealth of natural resources, there is very much that can be used from flora and fauna to treat various diseases, yellow wood is one of the plants that have medicinal properties and has not been widely studied, yellow wood is efficacious as antimicrobial, antioxidant, antihyperlipidemia, and anticancer. The objective of this study was to determine the class of chemical compounds found in simplicial and extracts of yellow wood plants and to determine the effect of extraction methods on the yield and phenolic levels of ethanol extracts of yellow wood plants. The stages of this research include processing plant materials, making maceration extracts and socletation of yellowwood plants, examination of characteristics, phytochemical screening and determination of total phenolic levels of ethanol extract 96% maceration and socleation of yellow wood (Arcangelisia flava (L.) Merr) by UV-Vis Spectrophotometry method. The highest yield research results are found in the maceration extract yield, this is because the maceration process time is shorter than the socleation process, so that the compound withdrawal process carried out by maceration is more optimal than the socleation method. In addition, the more solvent used, the more extracts produced. The determination of total phenolics is performed by determining the maximum wavelength of gallic acid using UV-Vis spectrophotometry methods. Yellowwood maceration ethanol extract has a total phenolic content of 22.0087 ± 0.8567 mg GAE/g and socleation extract has a total phenolic content of 18.2023 ± 0.1434 mg GAE/g.
Determination Of Total Alkaloid Content Of Yellow Wood (Arcangelisia flava (L.) Merr) Extract Based On Differences In Ethanol Concentration Using Uv-Vis Spectrophotometry Method Yuliana, Rika; Daulay, Anny Sartika; Ridwanto, Ridwanto; Rahman, Fathur
Indonesian Journal of Science and Pharmacy Vol. 1 No. 2 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i2.27

Abstract

Yellow wood with its secondary metabolites is one of the plants that has the potential as a traditional medicinal plant to treat various diseases, such as cancer. The chemical compounds contained in yellow wood are alkaloids, saponins, tannins, flavonoids, steroids/triterpenoids. The objective of this research was to determine the chemical compounds contained in ethanol extract and determine the total alkaloid value of yellow wood extract. This research method is an experimental method which includes processing plant materials, making ethanol extract concentrations of 50, 70 and 96%. Characterization examination, phytochemical screening and determination of total alkaloid levels of yellow wood extract by Uv-Vis spectrophotometry method. The results of phytochemical screening on yellow wood ethanol extract contain chemical compounds such as alkaloids, saponins, tannins, flavonoids, steroids/triterpenoids. Determination of total alkaloid levels is carried out by determining the maximum wavelength of caffeine, measuring the kaffein calibration curve and calculating total alkaloid levels using the Uv-Vis spectrophotometry method. Results The determination of total alkaloid levels in ethanol solvent extract concentration of 50% is 2.9649 ± 0.1767%, ethanol solvent extract with a concentration of 70% is 6.0180 ± 0.2469% and ethanol solvent extract with a concentration of 96% is 10.92001 ± 2.7803%.
Co-Authors Akbar, Windi Hari Ali Djamhuri Alistraja Dison Silalahi Alviana, Liya Anugrah, Bayu Asep Trizaldi Asparyzha, Rhyzha Azri, Atika Cici Andriani Daeng Elysa Putri Mambang Dalimunnthe, Gabena Indrayani Dalimunthe, Gabena Indriyani Dikki Miswanda Dina Agustia Parlin Dina Suciati Saragih Eva Fransiska Fadillah, Nike Fathur Rahman Fatur Rahman fatur Rahman, fatur Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Hafizha, Putri Harahap, Siti Salimah Haris Munandar Nasution Hasanah, Qori Hasrul Abdi Hasibuan Hindri Syahputri Ihsan Fadhilah Leni Handayani Lubis, Minda Sari M. Naufal Rifqi M. Pandapotan Nasution Makhfirah Manik, Umi Chairani Mardhatillah, Wulan Maya Syafira Mayang Sari Ritonga Merani Phaustina Lumban Gaol Miranza, Nona Muhammad Amin Nasution Muhammad Hizbullah Muhammad Wahyudi Munthe, Ariska Nabilla, Alfira nasution, Alfina Tri Utami Nasution, Nur Sahadah Nia Novranda Pertiwi Nst, Haris Munandar Nur Hanifah Nur'ain Harahap Nurhayati Nurhayati Nurul Salsa Abya Ritonga Pasaribu, Mesi Wilia Afrima Pasaribu, Mesi Willia Afrima Putri Intan Sari Putri Theresia Harianja Rafita Yuniarti Rahmadani Rahmadani Rahmasari, Siti Rahmi Ayusasmita Gultom Retno Sekarini Rezky , Deswita Ina Ricky Andi Syahputra Ridwanto Ridwanto Ridwanto Rika Yuliana, Rika Risma Fauziah Pasaribu Rizki, Rahmad Robiatun Rambe Rosaldi, Hikmah Sagita Marina Simatupang Sandika, M Teguh Sasnita, Merida Sekarini, Retno Siagian , Anggi Yani Sinaga, Novita Yulianti Sri Murni Sri Wahyuni Supiyani, Supiyani Syahfitri , Adelya Syahputra, Ricky Andi Syalsabila Putri Tuzzahra, Safira Yayuk Putri Rahayu Yayuk Putri Rahayu Yuniarti , Rafita Yuniarti, Rafita Zulmai Rani