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All Journal International Journal of Public Health Science (IJPHS) MEDIA MEDIKA INDONESIANA Jurnal Anestesi Perioperatif Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Medical Journal of Indonesia Indonesian Journal of Cancer Chemoprevention Pharmascience Majalah Kedokteran Sriwijaya Sari Pediatri Biomedical Journal of Indonesia Jurnal Kedokteran Gigi Universitas Padjadjaran Jurnal Kedokteran dan Kesehatan Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Ilmu Kedokteran dan Kesehatan Oceana Biomedicina Journal SRIWIJAYA JOURNAL OF MEDICINE Majalah Anestesia dan Critical Care Bioscientia Medicina : Journal of Biomedicine and Translational Research Sriwijaya Journal of Surgery Jurnal Kesehatan dan Pembangunan INTELEKTIUM Bioscientia Medicina : Journal of Biomedicine and Translational Research International Journal of Islamic and Complementary Medicine
Theodorus Theodorus
Bagian Farmakologi Fakultas Kedokteran Universitas Sriwijaya
Religion Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Other

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Journal : Majalah Anestesia dan Critical Care

 1 
Hubungan antara Klorheksidin 0,2% dan Povidone Iodine 1% dengan Ventilator-Associated Pneumonia (VAP): Studi Kohort Lestari, Mayang Indah; Puspita, Yusni; Zainal, Rizal; Theodorus, Theodorus
Majalah Anestesia dan Critical Care Vol 34 No 1 (2017): Februari
Publisher : Perdatin Pusat

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Abstract

Ventilator-associated pneumonia (VAP) adalah infeksi nosokomial tersering di ruang Intensive Care Unit (ICU) RSUP Dr. Moh. Hoesin (RSMH) Palembang, angka kejadiannya pada bulan Juli 2011–Juni 2012 cukup tinggi (31,69%) dengan angka mortalitas 54,7%. Mekanisme utama dalam patogenesis VAP ialah aspirasi bakteri gram positif dan negatif patogenik yang berkoloni di daerah orofaring. Tindakan modulasi kolonisasi tersebut sangat bermakna dalam mencegah VAP. Pemberian povidon iodin 1% dan klorheksidin 0,2% sudah sering dilakukan namun belum ada penelitian mengenai hubungannya terhadap kejadian VAP. Penelitian ini bertujuan untuk mengetahui hubungan antara klorheksidin 0,2% dan povidoneiodine 1% terhadap kejadian VAP. Studi kohort telah dilakukan di ICU RSMH pada bulan Februari – Juli 2014. Terdapat 32 subjek penelitian yang memenuhi kriteria inklusi dan dibagi menjadi dua kelompok, yaitu yang mendapatkan klorheksidin 0,2% dan povidoneiodine 1%. Dilakukan uji χ2 menggunakan statistical program and service solution (SPSS) versi 21.0. Karakteristik umum subjek penelitian yang meliputi usia, jenis kelamin, skor APACHE II, diagnosis, dan lama intubasi antara dua kelompok tidak menunjukkan perbedaan bermakna (p>0,05). Terdapat hubungan antara povidoneiodin 1% dan klorheksidin 0,2% terhadap kejadian VAP (RR 1,286) namun hubungan tersebut tidak bermakna (p=0,48). Kata kunci: Klorheksidin 0,2%, kolonisasi, orofaring, povidoneiodin 1%, ventilator associated pneumonia Relationship between Chlorhexidine 0.2% And Povidone Iodine 1% with Ventilator-Associated Pneumonia: Cohort Study Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in intensive care unit (ICU) in RSUP Dr. Moh. Hoesin (RSMH) Palembang, its incidence from July 2011 to June 2012 is quite high (31.69%) with mortality rate as high as 54.7%. Major mechanism in VAP pathogenesis is oropharygeal positive and negative pathogenic colonization aspiration. Colonization modulating intervention is signifantly important in VAP prevention. Povidoneiodine 1% and chlorhexidine 0.2% has been frequently used but there is no study yet about their correlation with VAP. This study was determined the correlation is between chlorhexidine 0.2% and povidone iodine 1% to VAP. Cohort study was conducted in ICU RSMH since February to July 2014. There was 32 subjects included and divided into two groups, chlorhexidine 0,2% and povidon iodine 1%. Analysis has been done with χ2 test by using SPSS® version 21.0. General characteristics among subjects in both groups including age, sex, APACHE II score on admission, diagnosis, and duration of intubation were not significantly different (p>0.05). There was a correlation between Povidoneiodine 1% and chlorhexidine 0.2% with VAP incidence (RR 1.286) but was not statistically significant (p=0.48).  Key words: Chlorhexidine 0.2%, colonization, oropharyngeal, povidon iodine 1%, ventilator-associated pneumonia
Co-Authors Abrar Arbhiwa Tanguirsyaf Siregar Abu Bakar Lutfi Adenan Abadi Adenan Abadi admin Adnan Abadi Asnawi Adnan Abadi, Adnan Afifa Ramadanti Afladhanti, Putri Mahirah Agustina Br. Haloho Agustinus William Agustria Z. Saleh Amarel, Fahma Alfarizqy Amir Fauzi Amirah Novaliani Anak Agung Gede Sugianthara Anang Tribowo Andriani, R.A. Linda Andriansyah, Yulius Andrina, Hana Angelica, Ellen Callista Anugrah Onie Awan Nurtjahyo Awan Nurtjahyo Azhar Susanto Azhari Azhari Azhari Rozali B, Firmansyah Benedictus Wicaksono Widodo Bernolian, N Bernolian, N Billy Sujatmiko D Saputra, Akbar N D.Y. Riyanto, D.Y. Dahler Bahrun Dandi, Dandi Daniatiek, Soneta Dastamuar, Shalita Debby Handayani Harahap Debby Handayati Harahap Devy Octarina Ditto Ruldifar Pribadi Doni Kurniawan Dwi Tantri Marylin Elvi Widiastuti Elza Iskandar, Elza Esterani, Esterani Evi Lusiana F, Amir Fahma Alfarizqy Amarel Fakhrudit, Emir Fatimah Syakirah Fauzit, Amir Fedriyansyah Fedriyansyah Ferdi, Roni Ferry Yusrizal Firmansyah Basir Fita Asfianti Forbes, Darlin Gita Dwi Prasasty H.M. Nazir H.M. Nazir Hamzah, Haidar Ali Harahap, Debby Handayani Heriansyah, Jhon Hidayat, Syarief Taufik Hilmawan, Bagus HM Nazir Hz Ika Kartika Indira, Tissa Ismail Bastomi, Ismail Julius Anzar Kamaluddin Kamaluddin Kamaluddin, MT Kamaluddin, MT Khrismawan Khrismawan Kms Yusuf Effendi Kms Yusuf Effendy Kusuma Harimin Leni Wijaya, Leni Lestari, Mayang Indah Lorenza, Geofanny Lutfi, Abu Bakar M Kamaluddin M. T. Kamaluddin Mahacakri, Eke P Mahadika, Febrinata Manan, Heriyadi Marta Hendry, Marta Martadiansyah, Abarham Maulani, H Maulani, H Maulani, Henni Mgs. Irsan Saleh, Mgs. Irsan Mgs. M. Irsan Saleh Muhammad Irsan Saleh Muhammad Totong Kamaluddin Mulawan Umar Muzakkie Muzakkie, Muzakkie Nadhif, Aufa Muhammad Nita Parisa Nopriansyah Darwin Novianesari, Putri H Novianty, Novianty Nugraha, M Daffa Nugroho, Achmadi S Nur Qodir Nurul Islamy Nuswil Bernolian Octarina, Bertha Oktariana, Desi Pangemanan, W T Pangemanan, W T Pangemanan, Wim T PATIYUS AGUSTIANSYAH, PATIYUS Puspita, Yusni Putri Mirani Putri, Safa Nabila Raden Ayu Kusuma Andini Rafiyandi Rafiyandi Rahima Rahima Renny Apliza Nasution Resiana Resiana Resti Resti Riani Erna Rika Saputri Rini Purnamasari Risa Vera Rizal Sanif Rizani Amran Rogatianus Bagus Pratignyo Romadhan, Muhammad Despriansyah Rose Mafiana Rostika Flora Rostika Flora Rusydi, Syakroni D Sabrina, Tia Sahab, Abdullah Saleh, Masagus Irsan Salni Sari Octarina Piko Sastradinata, Irawan Shaleh, Agustria Z Silvana, Rista Silvia Triratna Siti Rusdiana Puspa Dewi Sonlimar mangunsong Stevanny, Bella Sudarto Sudarto Sujatmiko, Billy Sulbahri, Robby P. Suriani Rosida Sutomo Tanzil Syarif Husin Syarif Husin Tahany, Hanifah Tanzil, Sutomo Tindar, Mirzah Tissa Indira Usman, Fatimah Veronita Veronita Veronita, Veronita Wahyu Pranata, Wahyu Pranata Weldy, Weldy Yohanes Febrianto Yulia Iriani, Yulia Yuliana Yuliana Yundari, Yundari Yusuf, Kemas Zainal, Rizal Zanaria, Rima Zulkifli Zulkifli