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Economic burden and healthcare costs of congenital anomalies of the kidney and urinary tract: a systematic review Alvarino, Akbar Muzakki; Pahlevi, Reza; Situmorang, Gerhard Renaldi; Wahyudi, Irfan; Rodjani, Arry; Raharja, Putu Angga Risky
Medical Journal of Indonesia Vol. 35 No. 1 (2026): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.258074

Abstract

BACKGROUND Congenital anomalies of the kidney and urinary tract (CAKUT) cause significant morbidity and economic burden worldwide, highlighting the needs to understand its associated costs. This study aimed to assess the economic burden of CAKUT management. METHODS A systematic review was conducted across 5 databases, including PubMed, ScienceDirect, ProQuest, Nature, and Google Scholar, for studies published up to September 11, 2024, focusing on both direct (e.g., hospitalizations, surgeries, and treatments) and indirect (e.g., lost work time and complications management) healthcare costs related to CAKUT and published in English. Non-economic studies, reviews, editorials, abstracts, animal/in vitro studies, and duplicates were excluded. Methodological quality was assessed using the Risk Of Bias In Non-randomized Studies - of Interventions tool. Narrative synthesis and descriptive statistics were applied. Cost-effectiveness analysis followed Joanna Briggs Institute guidelines. RESULTS 8 studies met the inclusion criteria, revealing wide variations in CAKUT-related healthcare costs across countries and interventions. These studies focused on reviewing both direct and indirect costs, along with interventions that reduce overall healthcare expenditure. Key findings include: (1) In the USA, bilateral renal agenesis costs averaged USD 26,032; (2) In Australia, early whole exome sequencing reduced diagnostic costs by 20% in genetic kidney disease cases; (3) Robotic surgery demonstrated long-term cost-effectiveness despite higher inpatient costs; (4) Other cost-saving strategies include the early renal ultrasound algorithm and genomic testing for CAKUT. CONCLUSIONS CAKUT imposes a significant and variable economic burden globally. Identifying cost-effective interventions is crucial for optimizing care and reducing the financial impact. Further research on cost management strategies is needed to improve outcomes and efficiency.
Writing Error: Exploring the Language Interference in EFL Context Cahyani, Aisyah Nur; Wahyudi, Irfan; Nadia, Farrah Maulida; Ramaniyah, Nadiatur; Dinanti, Ning Ayu; Lestari, Kinanti Dyah; Yulianti, Richa Dian; Hikmah, Durratul
International Journal of English Education and Linguistics (IJoEEL) Vol 5, No 1 (2023)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/ijoeel.v5i1.6590

Abstract

Al-Mashduqiah Plus Junior High School is one of the boarding school that develops foreign language skills as an attempt to prepare young people to be able to compete in the global world. In fact, the language learners (students) still often mix the structure of their first language into English to write. Therefore, this study aimed to identify the language interference in the students’ English writing assignment, and what factors behind them. The research used descriptive qualitative. The results showed that the form of interference in Al- Mashduqiah Plus Junior High School is morphological and syntactical structure. Besides, these interferences are caused by several factors; they are structural and non-structural factors. The structural factors include the difference of linguistics systems in native language and the targeted language. The non-structural factors include the learners’ bilingualism, language loyalty, the inadequate vocabulary of learners’ language, and the habits of using mother tongue language. This research is expected to provide information to students, teachers, and researchers so that they can find learning innovations that can improve the quality of foreign language skills.
Co-Authors Agus Rizal Ardy Hariandy Hamid, Agus Rizal Ardy Hariandy Alam, Gampo Albertus Marcelino Alfarissi, Fekhaza Alfarissi, Fekhaza Alvarino, Akbar Muzakki Andika Rendy Aria Kekalih ARIANTO, EKO Arry Rodjani Asy'ari, Nur Aini Shofiya Bagong Suyanto Bagus Baskoro Bettisari Napitupulu Bramono, Ikhlas A Cahyani, Aisyah Nur Chaidir A. Mochtar Chaidir Arif Mochtar CHAIDIR MOCHTAR, CHAIDIR Danurdoro, Aria Delta Bayu Murti Dinanti, Ning Ayu Durratul Hikmah Edhi Hapsari Endang Susalit Ervita Mediana Fatan Abshari, Fatan Fortuna, Edyna GAMPO ALAM IRDAM, GAMPO ALAM Gede Wirya Kusuma Duarsa Gerhard Reinaldi Situmorang, Gerhard Reinaldi Ginanda Putra Siregar, Ginanda Putra Happy Lumbantobing, Happy Heri Wibowo Hery Tiera Iannone, Aniello Ilham Wahyudi Ilmi, Irfan Immanuel Hutasoit, Yonas Intan Fitranisa Irdam, Gampo A Isnaini, Santi Johannes Aritonang, Johannes Jose RL Batubara Kanadi Sumadipradja Kholid, Irwan Layli Hamida Lestari, Kinanti Dyah Lisnawati Rachmadi Mandala, Opan Maradona, Maradona Mariati Hutabarat, Ida Maruhum B.H. Marbun Mohammad Fariz Muhamad Taufik Nadeak, Masaulina Klara Nadia, Farrah Maulida Naiborhu, Rusdin Nainggolan, Ebram NICHOLAS TAMBUNAN, NICHOLAS Nur Rasyid Nuraini, Dini Rahmatun Pakpahan, Romauli Pangestu, Chandra Trisna Ponco Birowo Prahara Yuri Prasetyo, Dimas Tri Putra, Ida Bagus Oka Widya Putra, Prima Ciko Ade Rachmah Ida Raharja, Putu Angga Risky Rahayu, Titik Puji Rama Firmanto, Rama Ramadhiansyah, Dimas Ramaniyah, Nadiatur Rani Sukma Ayu Suteja Ratih Puspa REZA PAHLEVI Romadhona, Mochamad Kevin Romdhi Fatkhur Rozi Ronaldo Kho Samosir, Ernita Santoso, Yuniawan Heru Saparudin Efendi Sapto Andriyono Saputra, Hijrah Sa’diyah, Kamila Sa’diyah, Kamilah Septiani, Dina Setyo Hariyanto, Didik Sholeh, Rio Nur Sihotang, Retta Catherina Situmorang, Gerhard Renaldi Soeroto, Adhitama A. Sri Endah Kinasih Tanaya Ghinorawa Taufik Rakhman Taher Toetik Koesbardiati Widi Atmoko Widia, Fina Widodo, Suko Wijaya, Gustaf Yacob Ruru Yonas Immanuel Hutasoit, Yonas Immanuel Yopie T Satyawan Yopie Tjandradiguna Satyawan Yosep, Eska Yudha Alfanius Hutahaean, Andre Yulianti, Richa Dian