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All Journal Journal of Food and Pharmaceutical Science Jurnal Informatika Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) INDONESIAN JOURNAL OF PHARMACY JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Sains dan Komunitas BERDIKARI : Jurnal Inovasi dan Penerapan Ipteks Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Abdimas Dewantara Media Farmasi WIDYA LAKSANA Aplikasia: Jurnal Aplikasi Ilmu-Ilmu Agama PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journals of Ners Community Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Ilmiah Cendekia Eksakta Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Indonesia Berdaya Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Mitra Masyarakat (JPMM) Journal of Food and Pharmaceutical Sciences Jurnal Pengabdian Masyarakat Panacea Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia
Iis Wahyuningsih
Fakultas Farmasi, Universitas Ahmad Dahlan
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Formulasi Solid Snedds (Self-Nano Emulsifying Drug Delivery System) Furosemid Dengan Pengering Aerosil Dan Aktivitas Diuretiknya Putri Dina Pelita; Iis Wahyuningsih; Sapto Yuliani
Journals of Ners Community Vol 13 No 1 (2022): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.1745

Abstract

Furosemid adalah obat golongan diuretika yang umum digunakan dalam terapi edema yang terkait dengan penyakit heart failure dan pada pengobatan hipertensi. Furosemid termasuk dalam Biopharmaceutical Class System (BCS) IV yang diketahui memiliki kelarutan dan permeabilitas yang rendah. Untuk mengatasi masalah tersebut dibuat sediaan Self-Nano Emusifying Drug Delivery System (SNEDDS). SNEDDS memiliki keterbatasan dalam hal stabilitas sehingga dilakukan penelitian lanjutan dengan membuat sediaan SNEDDS dalam bentuk padatan atau Solid SNEDDS (S-SNEDDS). Tujuan penelitian ini adalah memformulasi SNEDDS furosemid menjadi S-SNEDDS furosemid dan menentukan pengaruh S-SNEDDS furosemid terhadap aktivitas diuretikapada tikus dibandingkan dengan SNEDDS furosemid maupun furosemid saja tanpa modifikasi. Metode pembuatan S-SNEDDSfurosemid pengering aerosil dilakukan dengan metode absorbtion to solid carrier kemudian dilanjutkan pengujian karakterisasi kejernihan, waktu emulsifikasi, sifat alir, bulk density dan tapped density. Selanjutnya dilanjutkan uji aktivitas diuretika pada 25 ekor tikus jantan galur Wistar yang dibagi menjadi 5 kelompok yaitu kelompok normal, kontrol negatif diberi pembawa S-SNEDDS, perlakuan 1 diberi suspensi furosemid, perlakuan 2 diberi SNEDDS furosemid, perlakuan 3 diberi S-SNEDDSfurosemid dengan dosis 5,04 mg/KgBB. Seluruh kelompok diberikan perlakuan secara peroral lalu diperiksa volume urin yang dikeluarkan tikus pada jam ke 1, 2, 3, 4, 5 dan 6 setelah pemberian. Volume urin yang diperoleh di masing-masing kelompok dihitung rata-rata dan standar deviasinya kemudian dianalisis statistik dengan LSD dengan IBM SPSS (Statistical Product and Service Solution) 25 for Windows. S-SNEDDS furosemid dengan pengering aerosil memiliki karakteristik persen transmitan 96,94 ± 0,13 %, waktu emulsifikasi 7,40 ± 1,14 detik, sudut diam 31,71 ± 2,24, carr’s index 8,74 ± 0,49 dan hausner ratio 0,99 ± 0,10 dan dinyatakan memenuhi persyaratan. Hasil pengujian secara in vivo S-SNEDDS furosemid dengan pengering aerosil dapat meningkatkan volume urin kumulatif yang berbeda bermakna dengan kelompok kontrol negative pada dengan signifikansi lebih dari 0,05. Berdasarkan hasil penelitian dapat disimpulkan bahwa S-SNEDDS furosemid dengan pengering aerosil memiliki karakter dan aktivitas diuretika lebih baik dibandingkan dengan SNEDDS furosemid dan furosemid tanpa modifikasi.
Nanoemulgel activity of Binahong (Anredera cordifolia (Ten.) Steenis) leaf extract againts wound healing of hyperglycemic rats Magfirah Septiani Yusuf; Iis Wahyuningsih; Sapto Yuliani
Pharmaciana Vol 13, No 1 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (441.121 KB) | DOI: 10.12928/pharmaciana.v13i1.24600

Abstract

Hyperglycemia is associated with long-term damage, leading to the onset of wounds. The content of flavonoid compounds, steroids and saponins in Binahong leaves (Anredera cordifolia (Ten). Steenis) plays a role in the healing of diabetic wounds. The effectiveness of the active substance of the natural material is influenced by the large size of the particles, due to the presence of barier skin membranes. Nanoemulgel is an emulsion preparation with a droplet size of 1-100 nm which is suspended in a hydrogel. This study aims to determine the wound healing activity of diabetes in nanoemulgel preparations of binahong leaf extract (Anredera cordifolia (Ten.) Steenis) with its extract in male rats wistar hyperglycemia. The study was divided into 4 groups each consisting of 6 mice with diabetic wounds who got each a negative control group (glucose + nanoemulgel base), a positive control group (glucose + Madecassol 1%), a test group 1 (glucose + nanoemulgel, and a test group 2 (glucose + EDB). Treatment is carried out 2 times a day for 16 days. KGD measurements are carried out on the 0th, 1st, 5th, 14th and 21st days, and measurements of the diameter of the wounds are carried out on the 1st, 5th, 14th and 21st days. The KGD measurement results of the EDB nanoemulgel group decreased KGD by 52.91% on day 16 compared to the extract group which decreased by only 30.51% until the 16th day. The closure of the diabetic wounds of the EDB nanoemulgel group experienced closures of up to 52.91% compared to extracts that experienced closure of only 30.51% on day 16. The results of the one-way anova statistics showed a significant difference in the value of the decrease in kgd of the nanoemulgel preparation and its extract with the sig value. 0.045 and significant differences to the wound closure diameter of the diabetic EDB nanoemulgel group and its extract.
Protection Effect of Self-Nanoemulsifying Drug Delivery System (SNEDDS) Piroxicam as Ulcerogenic Agent towards Malondialdehid Level and Protein Expression of Caspase-3, COX-1, COX-2 at Rat Gastric Iis Wahyuningsih; Kurnia Ambarwati; Erninda Ayu Hapsari; Afifah Fauziyyah; Azis Ikhsanudin; Deasy Vanda Pertiwi; Wahyu Widyaningsih
Journal of Food and Pharmaceutical Sciences Vol 8, No 2 (2020): J. Food Pharm. Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.732

Abstract

The aim of this study was to determine the protection effect of SNEDDS piroxicam ulcerogenic agent against malondialdehyde (MDA) level and protein expression of caspase-3, COX-1, COX-2. The research was conducted using the test animals as much as 30 male white Sprague dawley (SD) rats aged 1-2 months with a weight of 100-200 grams divided into 5 groups. Treatment was given for 28 days orally. On the 29th day blood samples were also taken for the determination of MDA (Malondialdehid) levels by Thiobarbituric Acid Reactive Substance (TBARs) method using a visible spectrophotometer. Rats were sacrificed, then gastric organs were taken for immunohistochemical testing of caspase-3 and COX-1 expression, COX-2. The statistical analysis showed that the piroxicam SNEDDS group and the piroxicam suspension group decreased expression of the caspase-3 protein, increased COX-1 expression, decreased COX-2 and significantly decreased MDA levels. The piroxicam-containing SNEDDS (Self-Nanoemulsifying Drug Delivery System) form has protection against ulcogenic piroxicam.
Development of transdermal patch preparations binahong leaf extract (Anredera cordifolia (Ten.) Steenis) and antihyperglycemia test in rats Galang Pergiawan Ramadhan; Iis Wahyuningsih; Wahyu Widyaningsih
Pharmaciana Vol 13, No 2 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i1.24602

Abstract

Binahong leaves are plants that have great potential as antihyperglycemics, and have chemical content including triterpenoids, flavonoids, and saponins. However, the development of binahong leaves in pharmaceutical preparations is still very lacking. Objectives of this study are knowing the transdermal patch formulation of binahong leaf extract (BLE) produces good physical properties and the development of BLE transdermal patches with different extract concentrations may blood glucose lower (BGL) levels in glucose-induced mice. This study uses a single-layer patch because it has the advantage of being able to penetrate faster and is suitable for compounds that have solubility in polar solvents. The research began with the extraction of binahong leaves, then formulated a transdermal BLE patch using a formula that includes HPMC (polymer), glycerol (plasticizer), oleic acid (enhancer) and tween 80 (enhancer). Diabetic rats were divided into 4 groups of 6 rats, negative control group (glucose + placebo), positive control group (glucose + insulin), FI group (glucose+ transdermal patch BLE 30%), and FII group (glucose + transdermal patch BLE 47%). BGL measurements are carried out on the 0th, 3rd, 5th, and 7th days. The physical characterization carried out includes organoleptic, weight uniformity, thickness, pH, folding resistance, and moisture content, obtained FI and FII results that meet the requirements set out by each test standard. BGL (mg/dL) from day 1 to day 7 decreased in each group, positive control (68.8±3.76), negative control (112.5±6.89), FI (81.0±4.04), and FII (72.33±5.12). Based on the statistical results of the T-test on the physical evaluation of BLE transdermal patch preparations of FI and FII there were significant differences in weight and thickness uniformity, but there were no significant differences in pH, folding power, and humidity tests. The administration of a 47% BLE transdermal patch provides a faster but insignificant BGL reduction effect compared to the 30% BLE FI transdermal patch.
Peningkatan Pengetahuan dan Keterampilan Keluarga Aisyiyah Malaysia Dalam Pemanfaatan Rempah Secara Maksimal Yunda Maymanah Rahmadewi; Iis Wahyuningsih; Arif Budi Setianto
Indonesia Berdaya Vol 5, No 1 (2024)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.2024720

Abstract

Pimpinan Cabang Istimewa Aisyiyah (PCIA) Malaysia merupakan organisasi otonom Muhammadiyah yang mengakomodir potensi kaum ibu dan wanita dari kader, warga, simpatisan dan keluarga besar Aisyiyah di Malaysia. Tidak semua keluarga besar Aisyiyah memiliki pekerjaan yang tetap di Malaysia sehingga perlu tambahan dukungan ekonomi secara mandiri. Malaysia yang memiliki karakteristik geografis yang tidak berbeda jauh dengan Indonesia memiliki potensi tanaman yang serupa sehingga berpeluang dimanfaatkan oleh warga Aisyiyah dalam menjaga kesehatan secara mandiri melalui produk makanan maupun minuman. PkM ini bertujuan untuk meningkatkan pengetahuan dan ketrampilan Keluarga Aisyiyah Malaysia Melalui Keterampilan Pengolahan Herbal. Permasalahan diselesaikan dengan memberi pengetahuan dan ketrampilan mengolah Herbal. Metode pelaksanaan dilakukan dengan penyuluhan dan pelatihan dengan mitra sasaran yaitu Keluarga Aisyiyah Malaysia yang beranggotakan WNI dan warga negara Malaysia. Kegiatan penyuluhan dan pelatihan pemanfaatan rempah menghasilkan produk jamu beras kencur, permen marshmallow jahe, permen keras jahe, teh serai pandan, dan minuman serbuk jahe. Program ini dapat meningkatkan pengetahuan dan keterampilan masyarakat sasaran dalam pengolahan rempah
FORMULATION OF HAIR TONIC COMBINATION OF ETHANOL EXTRACTS OF MORINGA OLEIFERA LAM LEAVES AND FRAGRANT PANDAN (Pandanus Amaryllifolius Roxb) AND ITS ACTIVITY ON HAIR GROWTH IN WHITE RATS Reski Mulia; Iis Wahyuningsih; Moch Saiful Bachri; Sri Mulyaningsih
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1202

Abstract

Hair is the crown for everyone because hair functions aside from providing warmth, protection, beauty, and support. Hair loss that can cause baldness is one of the most serious problems for everyone. This study aimed to determine the activity of Hair Tonic combination formulations of kelor leaf ethanol extract (Moringa oleifera Lam.) and ethanol extracts of Fragrant Pandan  leaves (Pandanus amaryllifolius Roxb) on rat hair growth compared to single use. The method began with the maseration process of ethanol extract of kelor leaves and ethanol extract of Fragrant Pandan leaves, characterization of extracts (specific and non-specific parameters), chemical content testing of extracts and formulation of Hair Tonic preparations consisting of F1 (positive control), F2 (6% kelor leaf extract), F3 (6% ethanol pandan extract), F4 (combination of 2% kelor leaf extract with 4% ethanol pandan extract), F5 (3% kelor leaf ethanol extract and 3% ethanol pandan leaf extract), F6 (combination of 4% kelor leaf ethanol extract and 2% ethanol pandan leaf extract). The rat hair growth activity was divided into 8 groups: each rat's back was shaved to a size of 4 × 4 cm, the rats were left for 24 hours and then testing was carried out by spraying each formula, and hair growth was observed for 28 days. ...
In-vivo study of oleic acid and tween-80 on patch transdermal A.paniculata as anti-diabetic Wahyuningsih, Iis; Fadilah, Nur Aini; Widyaningsih, Wahyu
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.27851

Abstract

Sambiloto (Andrographis paniculata) has been known empirically as a plant that has benefits as a traditional antidiabetic Javanese medicine to treat diabetes mellitus (DM). The main compound contained in sambiloto is andrographolide which has a hypoglycemia effect. Andrographolide has low solubility in water and poor bioavailability due to biotransformation by P-glycoprotein in the intestinal tract which causes andrographolide to metabolize more quickly in the duodenum and jejunum. To overcome this extract ethanol of sambiloto (EES) formulated to patch transdermal. Enhancers can affect the characteristics of transdermal patch preparations which affect the pharmacological activity of transdermal patch preparations. The critical point of transdermal patch preparation is the selection of enhancers which is one of the compounds to increase the penetration of active substances in the skin by disrupting the permeability of the stratum corneum. The aim of this research is to determine the effect of variations in the combination of oleic acid and tween 80 as an enhancer on the physical characteristics of EES patches.The methods of extraction sambiloto use soxhetation with ethanol 96% as solvent. The formulation of EES patch transdermal using solvent casting technique with various concentration enhancer tween-80 and oleic acid. This research was conducted by making 3 formulas, where F1  (1:1), F2 (1:3) and F3 (1:3). The evaluations include weight uniformity, thickness, water content, pH and folding endurance of the patch. The result of visual appearance the patch EES has a dark green with aroma specific of EES. The characteristics of EES transdermal patches were affected by the ratio of tween-80 and oleic acid as the enhancers. The combination of oleic acid and tween 80 as a permeation enhancer has an influence on physical characteristics (weight and thickness) of EES patches.
Nanoemulsion Formulation Combination of Virgin Coconut Oil (VCO) and Candlenut Oil (Alleurites mollucanus) for Hair Growth in Male White Rats (Rattus novergicus) Rindi Ibrahim Lasanudin; Mochamad Saiful Bachri; Iis Wahyuningsih; Nur Ari Efiana
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 1 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i1.4348

Abstract

Having healthy and thick hair is the dream of many people, but some people have problems related to their hair. Hair problems that often occur are hair loss, thin hair or baldness, so to overcome these problems hair growth products have been made. Virgin Coconut Oil VCO and candlenut oil can be used as natural ingredients that can grow hair. The aim of this research was to determine the best nanoemulsion formulation for a combination of candlenut oil and VCO; and to determine the difference between applying nanoemulsion, conventional candlenut oil, conventional VCO and the oil emulsion on hair growth in male rats. This nanoemulsion formulation uses a combination of candlenut oil and VCO in a ratio of 1:1, 1:3 and 3:1. The nanoemulsion obtained was subjected to organoleptic, pH, viscosity, flow type and % transmittance. The best formulation was then tested for droplet size and zeta potential as well as hair growth activity tests using male rats. It was found that the best nanoemulsion formula was a nanoemulsion with a combination of 1:3 with a yellow color, a distinctive odor and clear with a droplet size of 14.42 ± 0.03 nm, a zeta value of -27.8 ± 1.02 mV, the length of the hair produced in the test hair growth activity was 17.14 ± 0.42 mm and hair weight was 699.37 ± 7.91 mg.
Upaya edukasi anemia dan tablet tambah darah pada siswi sekolah menengah kejuruan Gustinanda, Rizky; Handaningrum, Karunia Nining; Kaffah, Silmi; Wahyuningsih, Iis; Amukti, Danang Prasetyaning
Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Vol. 6 No. 1 (2025)
Publisher : Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jp2m.v6i1.22397

Abstract

Prevalensi anemia pada wanita meningkat dari 29,6% pada tahun 2019 menjadi 29,9% pada tahun 2021, menurut laporan Dinas Kesehatan Kota Yogyakarta mengenai prevalensi anemia pada remaja putri meningkat dari 37,1% pada tahun 2013 menjadi 48,9% pada tahun 2018. Anemia berdampak negatif terhadap pembelajaran, produktivitas, dan risiko infeksi. Di SMK Muhammadiyah 3 Yogyakarta, banyak siswi yang kurang memiliki kesadaran tentang anemia dan suplemen tablet tambah darah. Tujuan dilakukannya kegiatan pengabdian masyarakat ini memberikan pendidikan kesehatan dalam bentuk edukasi serta  pemberian tablet tambah darah sebagai upaya potensi pencegahan terjadinya anemia. Kegiatan program pemberdayaan umat (PRODAMAT) menerpakan metode Participatory Action Research (PAR) dengan memberikan materi tentang anemia dan obat tablet tambah darah (TTD) meliputi pengertian, gejala, faktor resiko, pencegahan dan cara pengguan TTD yang benar. Hasil yang diperoleh setelah dilaksanakan kegaitan sosialisasi edukasi  didapatkan hasil pre-test dan post-test terdapat peningkatan pengetahuan dari 26,6% menjadi sebesar 46,6%. Program ini juga melibatkan penyampaian materi, pembagian leaflet, dan diskusi interaktif untuk memperkuat pemahaman peserta. Intervensi ini terbukti efektif dalam meningkatkan kesadaran dan perilaku remaja putri terkait pencegahan anemia. Pendekatan edukasi berbasis partisipasi, seperti yang diterapkan, dapat terus dikembangkan untuk mendukung terciptanya generasi muda yang sehat dan sadar akan pentingnya menjaga pola hidup sehat. Penelitian ini menegaskan pentingnya kolaborasi antara sekolah dan komunitas dalam mengatasi masalah kesehatan remaja.
Reducing ulcerogenic effect of self-nano emulsifying drug delivery system of piroxicam Wahyuningsih, Iis; Widyaningsih, Wahyu; Wulandari, Silviana
Pharmaciana Vol. 8 No. 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v8i2.11478

Abstract

Piroxicam is antiinflammatory non-steroidal (AINS) drug group that has anti-inflammatory, analgesic and antipyretic effects. Like most other AINS drugs, piroxicam has low solubility and has gastrointestinal (ulcerogenic) side effects on long-term use. The nano-emulsifying drug delivery system (SNEDDS) is one of the technologies that can be used to overcome it. This study aims to determine the effect of ulcerogenic SNEDDS piroxicam compared with piroxicam formulas instead of SNEDDS. This study uses white rats male strain SD age 2-3 months and weight 100-200 grams of 40 rats. Rats divided into 5 groups. Group I was a normal control group, the test animals were given only water. Group II was a suspending control group treated with a 1% polyvinylpyrrolidone (PVP) solution, group III is a carrier control group treated with SNEDDS carrier which is a mixture of tween 80, virgin coconut oil (VCO) and polyethylene glycol (PEG) 400, group IV was a group of piroxicam drugs suspended with piroxicam 1.08 mg/kg in 1% PVP, group V was treated with SNEDDS piroxicam.Treatment was done for 28 days. After treatment, the gastric of rats were taken to be observed for ulcerogenic effects. Observations were made macroscopically by looking at ulcer scores followed by histopathological observations of tissue. The ulcer score data from each group were analyzed using one-way ANOVAand LSD test. The results showed that the normal control group, 1% PVP suspension and carrier group had a ulcer index of 0.0, 0.0 and 0.0, while the piroxicam suspension group and the SNEDDS group had an ulcer index of 0.88 and 0.0. These results were confirmed by histopathologic results of SNEDDS piroxicam to decrease the effect of pyroxicam ulcerogenic with results in the piroxicam suspension group has ulcer with necrosis by neutrophil infiltration, lymphocytes and mast cells in the mucosal tunica to submucosa. In the SNEDDS piroxicam group there is erosion with necrosis of the mucosal tunica epithelium with infiltration of lymphocytes and mast cells in submucosal tunica. It can be concluded the SNEDDS piroxicam can decrease the ulcerogenic effect.
Co-Authors AA Sudharmawan, AA Adi Permadi Adi Permadi, Adi Ag. Yuswanto Aji Setya Bakti Alam, Samsul Anggreni, Nova Annas Binarjo Anwar, Shinta Desy Anwar, Shinta Desy Any Guntarti Any Guntarti Arif Budi Setianto Aty Widyawaruyanti Azis Ikhsanudin Bakti, Aji Setya Danang Prasetyaning Amukti Deasy Vanda Pertiwi Defita Sari Depprelia Wahyu Sutanti Depprelia Wahyu Sutanti Ernidawati Erninda Ayu Hapsari Fadilah, Nur Aini Fauziyyah, Afifah Febrianika Ayu Kusumaningtyas Febrianti, Ririt Vita Fiftin Noviyanto Fiftin Noviyanto Firda Rahmadani Firda Rahmadani, Firda Fransisca, Indriyani Riski Fresiva, Urva Galang Pergiawan Ramadhan Gita Puspita Gustinanda, Rizky Handaningrum, Karunia Nining Hensi Setya Oktavia Hilma Putri Ibdal Satar Iin Narwanti Iin Narwanti Ikhsan Jaya Guntur Wicaksono Ilyas, Jenny Ima Dinny Rahmawaty Imam Riadi Indriyani Riski Fransisca Islamy, Muhammad Rido Islamy, Muhammad Rido Jenny Ilyas Kaffah, Silmi khusnul khotimah Kurnia Ambarwati Lina Widiyastuti Magfirah Septiani Yusuf Maghfirah, Rahmayani Moch Saiful Bachri Mochamad Saiful Bachri Muhammad Rido Islamy Muhammad Riski Pratama Muhammad Yusron Maulana El-Yunusi Narwanti, Iin Nazilah Shofi Risqina Nining Sugihartini Nining Sugihartini Nur Mahdi Nuri Ari Efiana Oci Widyastuti Oktavia, Hensi Setya Pelita, Putri Dina Pratama, Muhammad Riski Purwitasari, Neny Putri Dina Pelita Putri, Hilma Putri, Hilma Rahmawaty, Ima Dinny Rakhmawati, Kartika Rauhatun Napsah Reski Mulia Retno Widyowati Rindi Ibrahim Lasanudin Ririt Vita Febrianti Risqina, Nazilah Shofi Rodhia Ulfa Rohmiati Rohmiati Rohmiati, Rohmiati Rohmiati, Rohmiati Ronny Martien Ronny Martien Rustandi, Tedi Samsul Alam Sapto Yuliani Sapto Yuliani Sari, Defita Satar, Ibdal Sekar Prabawati Sembiring, Rinawati Shinta Desy Anwar Silviana Wulandari Sri Mulyaningsih Sri Mulyaningsih Sri Sulistyorini, Sri Srimuliani Arbie Sugiyanto - Sugiyanto Sugiyanto Sukardiman Sutanti, Depprelia Wahyu Tedy Setiadi Wahyu Widyaningsih Wahyu Widyaningsih Wahyu Widyaningsih Wahyuningtyas, Winda Wicaksono, Ikhsan Jaya Guntur Widyasari Putranti Widyastuti, Oci Winda Wahyuningtyas Wiwied Ekasari Wulandari, Silviana Wulandari, Silviana Yenni Latief Yudha Rizky Nuari Yunda Maymanah Rahmadewi Yunda Maymanah Rahmadewi Yuswanto, Ag