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All Journal Althea Medical Journal Sari Pediatri Paediatrica Indonesiana Jurnal Plastik Rekonstruksi World Nutrition Journal Indonesian Journal of Global Health research Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Narra J Proceedings of the International Conference on Nursing and Health Sciences eJournal Kedokteran Indonesia Makara Human Behavior Studies in Asia Jurnal Muara Medika dan Psikologi Klinis

Tjhin Wiguna

Departemen Ilmu Kedokteran Jiwa, Fakultas Kedokteran, Universitas Indonesia

Author-ID : 416956

Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Association Between Sensory Profile and Daily Functioning in Children with Autism Anindya, Isti; Soebandrio, Amin; Ariyanto, Ibnu Agus; Sekartini, Rini; Wiguna, Tjhin; Sari, Novika Purnama
Proceedings of the International Conference on Nursing and Health Sciences Vol 5 No 1 (2024): January-June 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v5i1.2787

In the diagnostic criteria outlined in the DSM-5-TR (APA, 2022) Autism is characterized by hyper- or hyporeactivity to sensory input or unusual interest. Children with Autism encounter challenges in processing sensory information, leading to difficulties in regulating responses to specific sensations and stimuli. Meanwhile, behaviours such as repetitive motor movements, running, aggression, and self-harming have been correlated with sensory processing disorders. Furthermore, some daily functioning that are often disrupted due to sensory processing disorders are sleeping, eating, and social activities. Therefore in this study, we aim to examine association between sensory profile and daily functioning in children with Autism. We collected data from parents of children aged 2-5 years with Autism (N = 96) and non Autism (N = 94) in Indonesia for three months (September-December 2023). Parents filled out five types of instruments (CARS-P, FISH, BAMBI, SCQ, and SSP) and sociodemographic data. The results of this study showed a significant difference between autistic and non-autistic groups in their daily functioning (p < 0.001). In autistic group, we found a significant relationship between sensory profiles and eating behavior (p < 0.001); and social communication skills (p < 0.001). In the non-autistic group, only sensory profile was corelated to eating behavior (p < 0.001). Primary results indicate that, the sensory profile is closely related to eating behavior and social communication skills in autistic children.

The Association Between Psychopathology Ans Quality Of Life In Burn Patients At Dr. Cipto Mangunkusumo Hospital, Jakarta Winanda, Rizki Aniza; Kusumadewi, Irmia; Wardhana, Aditya; Wiguna, Tjhin; Raharjanti, Natalia Widiasih
Jurnal Plastik Rekonstruksi Vol. 4 No. 2 (2017): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Background : Burns result in severe injuries that cause damage or loss of tissue due to contact with sources of heat resulting in injuries to all body systems. Injuries of the skin, which functions as a barrier to protect internal organs, may cause patients to experience damage to one's physical appearance and body image causing negative feelings that may lead to other problems such as psychopathology and symptoms of mental illness. Method : A cross sectional study with consecutive sampling method of burn patients who were treated at the Plastic Surgery Outpatient Clinic and Burn Unit of RSCM was conducted between April-May 2017. Subjects were asked to fill in self-report questionnaires including patient identity form, SRQ-20 (cutoff point ?6) for presence of psychopathology, and WHOQoL-BREF to obtain mean scores of quality of life that include four domains of physical, psychological, social, and environment assessment. Data collected was analyzed using correlation analysis. Result : 56 burn patients were included in the study. 30.4% did not work and 48.2% had very low income per month. 67.9% patients experienced burns due to fire and 44.6% had burns 10-30% of the TBSA with a majority of patients (80.4%) experiencing a combination of second & third degree burns. Based on the analysis, 57.1% of patients had a form of psychopathology and low mean scores of quality life (physical domain 48.1, psychological domain 51.5). Significant negative correlations (p ? 0.05) were obtained between the psychological domain and symptoms of depression, anxiety, low energy; physical domain and low energy; and social domain with anxiety. Conclusion: This study obtained significant results to identify the correlation between psychopathology and various domains of quality of life affected.

Effects of traditional music therapy on the psycho-neuro-immuno-endocrine aspect of burnout syndrome in healthcare workers: A randomized controlled trial Ardani, Yanuar; Shatri, Hamzah; Koesnoe, Sukamto; Yunir, Em; Wiguna, Tjhin; Wibowo, Heri; Sawitri, Dian R.; Sarwono, Sugeng J.; Masyur, Muhtaruddin; Ricardo, William; Katarina, Matilda; Anggono, Rendi F.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1686

Burnout syndrome (BOS) is an occupational phenomenon highly prevalent among healthcare workers, particularly physicians and nurses. Despite its prevalence, no single therapy universally addresses all cases of BOS. The aim of this study was to develop a novel approach to managing BOS through traditional music therapy, evaluated from psychosomatic, neurological, immunological, and endocrine perspectives. The study involved 80 participants who were randomly assigned to either the intervention or control group. The intervention group received traditional music therapy for 10–15 minutes, three times a week, over four weeks. Key outcomes were assessed at weeks 2 and 4. Measurements included the Maslach Burnout Inventory (MBI), heart rate variability (HRV), saliva cortisol, saliva β-endorphin, saliva immunoglobulin A (IgA), and serum FOXP3. Instruments included the MBI-HSS questionnaire and HRV measuring devices. Over four weeks, significant improvements were observed in the MBI scores (p=0.001), HRV (p=0.001), and FOXP3 delta (p=0.035) in the intervention group compared to the control group. However, no significant differences were found for cortisol, β-endorphin, or IgA. These findings suggest that traditional music therapy positively impacts the psychological, neurological, and immunological aspects of BOS and potentially influences immunological and endocrine responses. Future research should explore the effects of longer intervention durations, test varying doses, and examine the combination of music therapy with other non-pharmacological treatments to enhance its therapeutic potential.

Quality of life in episodic hypoxic children after emergency department or PICU hospitalization Yuniar, Irene; Julianti, Julianti; Gunardi, Hartono; Dewi, Rismala; Wiguna, Tjhin; Lubis, Munar
Paediatrica Indonesiana Vol. 65 No. 5 (2025): September 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.5.2025.357-63

Background Studies on long–term outcomes of hypoxic children after being hospitalized are limited, even though hypoxia is known to affect their quality of life (QoL). Objective To assess the QoL of children with episodic hypoxia following hospitalization in the emergency department (ED) and Pediatric Intensive Care Unit (PICU). Methods A prospective cohort design study targeting pediatric patients aged 2–7 years with critical illness was conducted at Dr. Cipto Mangunkusumo Hospital. Inclusion criteria are hypoxia patients receiving oxygen therapy, defined from the ratio of partial arterial oxygen pressure and inspired oxygen (PaO2/FiO2). The PedsQLTM questionnaire was used to assess QoL at the time of admission and 3 months after hypoxia event. Patients with cerebral palsy, mental retardation, chromosomal abnormalities, liver transplantation, and length of stay ≤24 hours were excluded. Data distribution in numerical form was analyzed using the Kolmogorov–Smirnov test. Results Forty-six children with a median age of 4 (2–7) years had decreased QoL at 3 months after episodic hypoxia, based on PedsQLTM scores. The physical, emotional, and social domains were significantly decreased (P<0.01) compared to QoL at the time of admission. Prior to admission, 78.3% of children had already experienced impaired QoL. Conclusion Children with episodic hypoxia demonstrated a decline in QoL at 3 months after hypoxia event based on PedsQLTM scores. Specifically, the physical, emotional, and social domains were significantly decreased compared to at the time of admission.

Validation and reliability testing of Reflective Functioning Questionnaire (RFQ) Indonesian Version Mahaputra, Mahaputra; Sylvia Detri Elvira; Petrin Redayani Lukman; Martina Wiwiek Nasrun; Tjhin Wiguna
Jurnal Psikiatri Surabaya Vol. 14 No. 2 (2025): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i2.55541

Introduction: Reflective function refers to the capacity to comprehend emotions, beliefs, and behaviors in oneself and others. Mental disorders are frequently associated with deficits in mentalizing capabilities. These deficits compromise an individual’s capacity for self-reflection and understanding of mental states, impeding one’s ability to regulate both mental states and interpersonal relationships. The Reflective Functioning Questionnaire (RFQ) is a practical tool to measure reflective function, but it has not yet been adapted into Indonesian, a crucial step toward addressing the needs of local populations. This study aimed to develop an Indonesian version of the RFQ with robust validity and reliability. Methods: The English RFQ was translated into Indonesian using standard guidelines, including forward and backward translation by certified translators. Content and face validity were assessed through expert panel reviews to ensure cultural and linguistic relevance. Construct validity was evaluated using confirmatory factor analysis (CFA), and reliability testing was conducted using Cronbach’s Alpha. A pilot study with 10 subjects was conducted to refine the instrument, followed by testing with a sample of 100 participants. Results: The final Indonesian RFQ consists of 11 items across two subscales: RFQu and RFQc. CFA indicated a good model fit (χ² = 1.16, p = 0.55, and RMSEA = 0.041). Reliability testing showed strong internal consistency, with Cronbach’s Alpha values of 0.89 for RFQc and 0.87 for RFQu. Conclusion: The modified Indonesian RFQ demonstrated excellent validity and reliability, providing a robust tool for assessing reflective function in clinical and research settings.

Social-emotional development in early life: what happens and how to optimize it Medise, Bernie Endyarni; Wiguna, Tjhin; Dharma Asih, Ni Ketut Susila
World Nutrition Journal Vol. 5 No. S2 (2022): Special Issue : critical aspects of early life nutrition, gut health, and deve
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.S2.0002

The Physical, metabolic, emotional, cognitive, and social development all begin to develop during early years of childhood.. Social and emotional competencies are increasingly recognized as critical for children's success, in school and in later phases of life into adulthood. According to new research, changes in the gastrointestinal tract's development during the early postnatal period can affect brain development and vice versa., collectively called the gut-brain axis. The gut microbiota has an impact on a variety of mental processes and phenomena, as well as being involved in the pathophysiology of a variety of mental and neurological diseases.. Insights in this area can be targeted through dietary treatments to improve cognitive outcomes in newborns by optimizing the link between the gastrointestinal system and the brain. Further, having a healthy and happy human life could be ensured by acquiring adequate and balance microbiota

Experts’ Opinion on Immunity and Nutrition to Support Key Cognitive Functions Sekartini, Rini; Surapsari, Juwalita; Oktarina, Molly Dumakuri; Wiguna, Tjhin; Pasiak, Taufiq Fredrik; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie; Wasito, Erika
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0001

The interaction of micronutrients and macronutrients has been shown to have a significant impact on children's cognitive development. Furthermore, proper nutrition helps a child's immune system avoid infection and disease, which can impair nutrient absorption and lead to deficiency. Microbiotas in the gut play critical roles in body physiology, including nutrient absorption, infection resistance and immune system development. Furthermore, it is known that the gut microbiota influences immune cell maturation. Finally, these three factors are thought to influence neurogenesis and cognitive development. A virtual meeting was held with five invited experts to gain a better understanding of the relationship between nutritional factors, the immune system and cognitive development.

Prevalence and associated factors of infantile colic in infants of mothers in medical residency program Muzal Kadim; Wira Febrisandi Irsan; Tjhin Wiguna; Dina Muktiarti; Sulaiman Yusuf; Ade Rachmat Yudianto; Yusri Dianne Jurnalis; Yudith Setiati Ermaya; Wahyu Damayanti; Andy Darma; Christy Venada
Paediatrica Indonesiana Vol. 66 No. 1 (2026): January 2026
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background Infantile colic, defined according to the Rome IV criteria as excessive crying in otherwise healthy infants without signs of illness or failure to thrive, could be linked to inadequate mother–infant bonding. The risk of infantile colic is increased in mothers with depression and insufficient family support. Infantile colic could lead to recurrent emergency department admissions, unnecessary treatments, and child abuse. Mothers in medical residency programs who often face long working hours, reduced bonding time with their infants, burnout, and depression, may be at an increased risk of having infants with colic. However, data on the prevalence and associated factors of infantile colic in infants of mothers in this specific population are lacking. Objective To determine the prevalence of infantile colic and its associated factors among infants of mothers participating in medical residency programs. Methods We conducted a cross-sectional study involving 67 infants of mothers in medical residency programs across seven centers in Java and Sumatra. We used the Indonesian-translated Parent Report Questionnaire for Children Aged 0-3 Years from the Rome Foundation to obtain information on infantile colic based on Rome IV criteria and the Indonesian version of the Mother-Infant Bonding Scale Questionnaire to assess the risk level of mother-infant bonding problems. An online questionnaire was distributed to subjects’ mothers via WhatsApp© application. Results Of 67 subjects, 18 (26.8%) experienced infantile colic. High risk of mother–infant bonding problems, as indicated by elevated Mother-Infant Bonding Scale-Indonesian version (MIBS-I) scores, were significantly associated with infantile colic (OR 2.922; 95%CI 1.07 to 4.87; P=0.046). The type of nutrition, whether breast milk or a combination of formula and breast milk, did not significantly differ between infants with and without colic (OR 1.333; 95%CI 0.451 to 3.940; P=0.602). Conclusion Elevated MIBS-I scores, reflecting impaired mother–infant bonding, are ssociated with an increased risk of infantile colic in infants born to mothers in medical residency training programs.

Internet Gaming Disorder Among Junior High School Adolescents in Jakarta: A Comparative Analysis Between Public and Private Schools Eva Suryani; Tjhin Wiguna; Listya Tresnanti Mirtha; Kristiana Siste; Rini Sekartini; Sabarinah Sabarinah; Alida R. Harahap; Luh Nyoman Alit Aryani
Althea Medical Journal Vol 13, No 2 (2026)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v13n2.4784

Background: The increasing availability of mobile games and expandinng access to devices have contributed to the growing prevalence of Internet Gaming Disorder (IGD), particularly among adolescents. The IGD is associated with impaired well-being and functioning, including sleep, psychological, academic, and social problems. However, evidence regarding effective school-based interventions remains limited. This study aimed to explore the prevalence of IGD among junior high school students in public and private schools in Jakarta, Indonesia. Methods: An analytic observational study with a cross-sectional design was conducted among 2,320 junior high school students from January to August 2025. Demographic data were collected using a basic questionnaire, and IGD was assessed using the Internet Gaming Disorder Test-10 (IGDT-10). Data were analyzed using the Chi-square test and Mann–Whitney test with SPSS version 23.0Results: The prevalence of Internet Gaming Disorder (IGD) among junior high school adolescents in Jakarta was 2.2%. In private school, IGD was significantly associated with duration of gaming ≥4 hours/day and male gender, whereas in public school, IGD was significantly associated with the use of multiple gaming devices.Conclusions: The prevalence of IGD among junior high school students in Jakarta was 2.2%. Factors associated with IGD varied between public and private schools, suggesting that prevention strategies should be tailored to the school context. Early identification of excessive gaming behaviors may support adolescent well-being and healthy development.

Model of Risk Factors Identification: A Qualitative Approach to Mitigate Pilot Errors in Indonesia Inne Yuliawati; Budi Sampurna; Tjhin Wiguna; Imam Subekti; Widura Imam Mustopo; Aria Kekalih
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6698

Pilot errors accounts for 80% of accidents and 50% of serious incidents, thus identifying the risk factors is crucial to mitigation strategies. The research aimed to develop a model of pilot errors’ risk factors identification and mitigation by conducting a Focus Group Discussion (FGD) with stakeholders in Indonesia. This was a qualitative analysis by conducting hybrid FGD, divided into four groups of experts consisted of officials from the Directorate General Civil Aviation, human factors experts, active pilots and investigators from the National Transport Safety Committee, from 28 to 29 August 2024. The data was collected by transcribing verbatim transcript, then analysed using the Steps for Coding and Theorization and Content Validity Index. model was developed, consisted of pilots’ risk factors, divided into three themes, 16 sub-themes, grouped into internal and external factors, which can be identified by four activities and can be mitigated by three activities. The factors contributed to aviation safety are multifactorial and interrelated. The complexity of pilots’ risk factors involves a continuous assessment of identification and mitigation, emphasizes the adaptive collaboration among stakeholders. A significant contribution in aviation human factors data for the Safety Management System implementation in Indonesia.

Co-Authors A.A.A.A Kusumawardhani Ade Rachmat Yudianto Aditya Wardhana Agung Kusumawardhani Agung Muhammad Rheza Alida R. Harahap Amin Soebandrio Anak Agung Ayu Agung Kusumawardhani Anastasia Maureen Andika Widianti Andy Darma Anggono, Rendi F. Anindya, Isti Ardani, Yanuar Aria Kekalih Basrowi, Ray Wagiu Batubara, Jose Bernie Endyarni Medise Bonny Tjongjono Budi Sampurna Christa Pamela Christian, Hans Christy Venada Citra Fitri Agustina Dharma Asih, Ni Ketut Susila Dian R. Sawitri, Dian R. Dina Muktiarti, Dina E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Em Yunir, Em Erika Wasito Eva Suryani Evi Evi Evi Evi Firdaus, Karina Fransiscus D. Suyatna Fransiska Kaligis H.F. Wulandari Hartono Gunardi Heri Wibowo Ibnu Agus Ariyanto Ika Widyawati Imran Pambudi Inne Yuliawati Irawan Mangunatmadja Irene Yuniar, Irene Irmia Kusumadewi Ismail, Raden Ismail, Raden Irawati Jubilate Edward Iruanto Tambun Julianti Julianti, Julianti Juwalita Surapsari Kartjito, Melissa Stephanie Katarina, Matilda Kristiana Siste Kurniasanti, Kristiana Kurniasanti, Kristiana Siste Kusuma Minayati Levina Chandra Khoe Listya Tresnanti Mirtha Luh Nyoman Alit Aryani Mahaputra Mahaputra, Mahaputra Malik, Khamelia Martina Wiwie Setiawan Nasrun Martina Wiwiek Nasrun Masyur, Muhtaruddin Melissa Stephanie Kartjito Munar Lubis Munasir, Zakiudin Muzal Kadim Myron L. Belfer Naela Fadhila Noorhana Setyawati WR Nurmiati Amir Nurmiati Amir Oktarina, Molly Dumakuri Osi Kusuma Sari Pasiak, Taufiq Fredrik Paul Samuel Kris Manengkei Petrin Redayani Lukman Pratiwi Assandi Pustika Amalia Wahidiyat Putra, Anggi A. Raharjanti, Natalia Widiasih Ray Wagiu Basrowi Ricardo, William Rini Sekartini Rininta Mardiani Rismala Dewi Rivo Mario Warouw Lintuuran Rosalina Dewi Roeslani, Rosalina Dewi Sabarinah Prasetyo Sabrina Tan Safira A Tjandrasari Sari, Novika Purnama Sarwono, Sugeng J. Sasanto Wibisono Sekarpramita Darmaputri Soedjatmiko Subekti, Imam Sudigdo Sastroasmoro Sudung O Pardede, Sudung O Sukamto Koesnoe Sulaiman Yusuf Surapsari, Juwalita Sylvia D Elvira Taufiq Fredrik Pasiak Tonny Sundjaya Tribowo Tuahta Ginting Wafa Sofia Fitri Wahyu Damayanti Waldi Nurhamzah Wasito, Erika Widura Imam Mustopo Winanda, Rizki Aniza Windy Atika Hapsari Wira Febrisandi Irsan Wiwie, Martina Yudith Setiati Ermaya Yunita Arihandayani Yusri Dianne Jurnalis

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