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All Journal Jurnal Kesehatan Andalas Jurnal Sains dan Teknologi Farmasi Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Majalah Kedokteran Andalas Jurnal Farmasi Higea Indonesian Journal of Anesthesiology and Reanimation (IJAR) Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah Frontiers on Healthcare Research
Erlina Rustam
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Agriculture, Biological Sciences & Forestry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Peranan Skor SOFA dan Prokalsitonin dalam Memprediksi Luaran Mortalitas Sepsis di ICU: Sebuah Tinjauan Naratif Catherina, Felicia; Syahrul, Muhammad Zulfadli; Rustam, Erlina
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 3 (2025): September 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i3.1326

Abstract

Background: Sepsis is a dysregulated host response to infection that leads to life-threatening organ dysfunction. SOFA score is used to assess the degree of organ dysfunction and is currently used in the latest sepsis definition. PCT is a biomarker which increases in inflammation and sepsis. Objective: to analyze the role of SOFA score and procalcitonin in predicting sepsis mortality outcome in ICU. Methods: Literature review discusses primary literature searched through PubMed and ScienceDirect databases, selected based on predetermined inclusion and exclusion criteria. Results: A total of 15 articles were included in this review. In studies evaluated a single SOFA score were found that the mean/median SOFA score in non-survivors were significantly higher than in survivors. In studies evaluated SOFA score data serially also showed the ability of SOFA score to predict mortality outcomes. One-time PCT measurements were performed in 93% studies in this review. The results obtained were that the mean/median initial PCT levels measured at admission or after sepsis diagnosis in non-survivors were higher than in survivors in 13 studies, but statistically significant differences were only found in 5 studies. Serial PCT measurements were only measured in 1 study, it found changes in PCT values on ICU admission and fifth day are significantly related to mortality. Conclusion: SOFA score is a good parameter for predicting sepsis mortality outcome in ICU, and in general, one-time PCT measurements do not play a significant role in predicting sepsis mortality outcome in ICU.
PREVALENSI ANEMIA PADA KEHAMILAN : SEBUAH TINJAUAN LITERATUR SISTEMATIS Azmira, Nazurah; Defrin, Defrin; Burhan, Ida Rahmah; Rustam, Erlina; Antonius, Puja Agung; Yusri, Elfira
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 9 (2025): SINERGI : Jurnal Riset Ilmiah, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i9.1374

Abstract

Background : Anemia has become a public health problem that bring many potencial danger to both maternal and neonatal side. Many studies show that there are significant correlation between maternal mortality and anemia during pregnancy.Objective: This review is done to determine the prevalence and risk factors of anemia among pregnant women Methods : This study is a systematic literature review focused on the prevalence of anemia during pregnancy from 2011-2020. Literature search on Pubmed and Proquest databases was carried out to identify studies included in inclusion criteria related to prevalence of anemia during pregnancy. In this review, 60 articles were reviewed after 4105 articles found in both databases were screened using PRISMA guidelines. A total of 49589 participants from 20 developing countries were included. Results : The results showed that the rate of anemia in pregnancy range from 7,4% to 90%, with an average of 36,2%. The most reported risk factors are low economic level/ household income (10,2%), maternal age (9,6), rural residence (7,8%), educational status of the mother (7,2%)and less consumption of iron/folic acid (7,2%). Conclusion : Based on the review, available evidence suggest that prevalence of anemia remain high especially in low and middle income countries. Maximum efforts need to be initiated to help prevent anemia during pregnancies. Public should be educated on early initiation of antenatal care to enhance surveillance, identification and treatment of anemia
Hubungan Pemakaian Obat Antiinflamasi Nonsteroid (OAINS) dengan Derajat Keparahan Dispepsia pada Pasien Osteoartritis di Wilayah Kerja Puskesmas Kuranji Kota Padang Muhammad Fadli; Rustam, Erlina; Syahrul, Muhammad Zulfadli; Usman, Elly; Miro, Saptino; Kadri, Husnil
Majalah Kedokteran Andalas Vol. 48 No. 4 (2025): MKA October 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i4.p373-382.2025

Abstract

Latar Belakang: Di layanan primer, OA sering ditangani dengan OAINS, namun efek samping gastrointestinal seperti dispepsia kerap menurunkan kualitas hidup. Objektif: Menilai hubungan pemakaian OAINS dan durasinya dengan derajat keparahan dispepsia pada pasien OA di wilayah kerja Puskesmas Kuranji, Kota Padang. Metode: Studi potong lintang menggunakan data primer melalui wawancara terstruktur terhadap 101 pasien OA yang sedang menjalani terapi OAINS. Analisis menggunakan uji chi square. Hasil: Mayoritas responden berusia >60 tahun 54,5 persen, perempuan 79,2 persen. Natrium Diklofenak merupakan OAINS tersering 84,2 persen, dengan durasi penggunaan >3 bulan 56,4 persen. Terdapat hubungan pemakaian OAINS dengan dispepsia p=0,000, dan hubungan durasi penggunaan OAINS dengan derajat keparahan dispepsia p=0,001. Kesimpulan: Pada pasien OA di layanan primer, pemakaian dan durasi OAINS berkaitan dengan dispepsia dan tingkat keparahannya. Temuan ini menegaskan pentingnya skrining gejala cerna, edukasi pasien, serta peninjauan regimen analgesik yang lebih aman. Pertimbangkan gastroproteksi dan pemantauan berkala pada kelompok berisiko tinggi secara klinis.
The Use of Dexmedetomidine, Midazolam, and Ketamine in Prevention of Emergence Agitation in Pediatric Patients Undergoing Surgery Under General Anesthesia Syilfana, Hanifah; Indra, Beni; Welan, Rahmani; Effendi, Rinal; Rustam, Erlina
Indonesian Journal of Anesthesiology and Reanimation Vol. 6 No. 2 (2024): Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Publisher : Faculty of Medicine-Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijar.V6I22024.116-124

Abstract

Introduction: Emergence agitation (EA) is a problem that often occurs in pediatric patients during recovery from anesthesia. The cause of EA remained unclear, but the combination of etiologies increases the risk of postoperative agitation. The researchers use various drugs such as ketamine, midazolam, and dexmedetomidine to prevent and treat EA. Objective: This review aims to determine the effectiveness of dexmedetomidine, midazolam, and ketamine in preventing emergence agitation in pediatric patients undergoing surgery under general anesthesia. Method: This literature review is a narrative review that looks at the outcomes of randomized controlled trials (RCT) studies that tested how well dexmedetomidine, midazolam, and ketamine worked at keeping pediatric patients from becoming agitated during emergence. Literature was collected through Google Scholar and PubMed using the keywords Pediatric, Children, Dexmedetomidine, Ketamine, Midazolam, Emergence Agitation, Emergence Delirium, Postoperative Agitation, and Postoperative Delirium and published within the last ten years (2011–2021) in English or Indonesian. The researchers excluded articles that were not available in full, as well as literature reviews. Results: Based on the specified database and keywords identified, there were 695 articles. This literature study included thirteen articles that met the inclusion criteria. Ten articles examined the effectiveness of dexmedetomidine, four reviewed the effectiveness of midazolam, and three examined the effectiveness of ketamine. Conclusion: According to the ten reviewed articles, administering dexmedetomidine or ketamine reduced the incidence of emergence agitation in children. However, the administration of midazolam yielded inconsistent results. To evaluate the optimal dosage, route, and timing of dexmedetomidine, midazolam, and ketamine in preventing EA, further studies are necessary.
Hubungan Pola Penggunaan Hand Sanitizer dengan Kejadian Dermatitis Tangan Pada Mahasiswa Program Studi Kedokteran Fakultas Kedokteran Universitas Andalas Zafira, Qory; Akhyar, Gardenia; Rustam, Erlina; Julizar, Julizar; Gustia, Rina; Afdal, Afdal
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 1 (2024): Maret 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i1.1046

Abstract

Latar Belakang: Pandemi Covid-19 membuat masyarakat menjalankan pola hidup baru dengan menerapkan protokol kesehatan dengan membersihkan tangan menggunakan hand sanitizer. Hand sanitizer diformulasikan untuk dapat menghambat dan membunuh mikroorganisme dengan cara mendenaturasi lipid, namun efek dari cara kerjanya ini dapat meningkatkan risiko terjadinya dermatitis tangan. Objektif: Penelitian ini bertujuan untuk mengetahui hubungan pola penggunaan hand sanitizer dengan kejadian dermatitis tangan. Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross-sectional study dengan teknik simple random sampling pada mahasiswa Program Studi Kedokteran Fakultas Kedokteran Universitas Andalas Angkatan 2021 dengan jumlah sampel sebanyak 80 orang. Data responden diperoleh dari kuesioner dan dianalisis menggunakan uji chi square. Hasil: Hasil penelitian ini didapatkan sebagian besar mahasiswa menggunakan hand sanitizer lebih dari 6 bulan (82,5%) dengan frekuensi 1 sampai 5 kali dalam sehari (86,3%). Lebih dari setengah mahasiswa menggosok tangan kurang dari 10 detik setiap menggunakan hand sanitizer (75%), dan tidak menggunakan pelembab (57,5%). Sebagian besar mahasiswa tidak mengalami dermatitis tangan (77,5%) dan tidak memiliki riwayat atopi (80%). Tidak terdapat hubungan yang signifikan antara durasi penggunaan, frekuensi penggunaan, durasi scrubbing penggunaan hand sanitizer dan penggunaan pelembab dengan kejadian dermatitis tangan dengan nilai p=0.599 untuk durasi penggunaan, p=0.086 untuk frekuensi penggunaan, p=1.00 untuk durasi scrubbing, dan p=0.316 untuk penggunaan pelembab. Terdapat hubungan antara riwayat atopi dengan kejadian dermatitis tangan dengan nilai p=0,000. Simpulan: Tidak terdapat hubungan yang signifikan antara pola penggunaan hand sanitizer dengan kejadian dermatitis tangan khususnya durasi penggunaan, frekuensi, dan durasi scrubbing dan penggunaan pelembab, namun terdapat hubungan antara riwayat atopi dengan kejadian dermatitis tangan. Kata kunci: Pola penggunaan hand sanitizer, dermatitis tangan
Hubungan Kanker Payudara Tripel Negatif dengan Kejadian Metastasis Aksila dan Metastasis Jauh di RSUP Dr. M. Djamil Padang Nindita, Priska Audina; Handayani, Tuti; Suchitra, Avit; Khambri, Daan; Mulyani, Henny; Rustam, Erlina
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 1 (2024): Maret 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i1.1137

Abstract

Latar Belakang: Lebih dari 90% kematian terkait kanker payudara disebabkan oleh tumor sekunder di organ yang jauh akibat metastasis. Kanker payudara tripel negatif atau triple negative breast cancer (TNBC) merupakan subtipe paling agresif diantara subtipe lainnya. Secara klinis TNBC memiliki ukuran tumor yang lebih besar, melibatkan kelenjar getah bening, dan memiliki derajat keganasan yang lebih buruk. Pasien TNBC lebih berisiko mengalami metastasis dan kematian dibandingkan dengan jenis subtipe lainnya sehingga prognosisnya juga lebih buruk. Objektif: Mengetahui hubungan kanker payudara tripel negatif dengan kejadian metastasis aksila dan metastasis jauh di RSUP Dr. M. Djamil Padang. Metode: Penelitian analitik observasional dengan desain penelitian cross-sectional bersifat retrospektif. Jumlah sampel penelitian sebanyak 11 pasien TNBC dan 99 pasien non-TNBC di RSUP Dr. M. Djamil Padang tahun 2016 – 2021. Digunakan analisis uji Chi Square. Hasil: Kejadian metastasis aksila pada pasien TNBC sebesar 45,5% dan kejadian metastasis jauh sebesar 90,9% dengan lokasi metastasis terbanyak pada organ paru. Tidak terdapat hubungan antara kanker payudara tripel negatif dengan kejadian metastasis aksila (p=0,071) dan terdapat hubungan bermakna antara kanker payudara tripel negatif dengan kejadian metastasis jauh (p=0,018). Kesimpulan: Penelitian ini dapat disimpulkan bahwa tidak terdapat hubungan antara kanker payudara tripel negatif dengan kejadian metastasis aksila dan terdapat hubungan antara kanker payudara tripel negatif dengan kejadian metastasis jauh. Kata kunci: kanker payudara, tripel negatif, metastasis
Prevalensi dan Faktor Risiko Self-Injury pada Mahasiswa Fakultas Kedokteran Universitas Andalas Angkatan 2021 dan 2022 Luthfi, Muhammad; Yaunin, Yaslinda; Rustam, Erlina; Rini Gusya Liza; Cimi Ilmiawati; Yulistini
Majalah Kedokteran Andalas Vol. 48 No. 4 (2025): MKA October 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i4.p400-411.2025

Abstract

Latar Belakang: Self-injury merupakan gangguan kesehatan mental yang banyak dialami oleh remaja dan dewasa muda. Faktor risiko yang dapat mendorong terjadinya perilaku self-injury yaitu jenis kelamin, usia, gangguan perilaku, gangguan mental, perundungan, dan permasalahan interpersonal. Objektif: Mengetahui prevalensi dan faktor risiko self-injury pada mahasiswa Fakultas Kedokteran Universitas Andalas Angkatan 2021 dan 2022. Metode: Penelitian ini merupakan penelitian deskriptif. Penelitian dilakukan pada mahasiswa Fakultas Kedokteran Universitas Andalas. Data pada penelitian ini dikumpulkan dengan menggunakan pertanyaan kuesioner. Jumlah sampel pada penelitian ini sebanyak 288 orang mahasiswa. Hasil: Mahasiswa kedokteran yang pernah melakukan self-injury sebanyak 49 orang (17%). Responden yang pernah melakukan self-injury cenderung memiliki karakteristik berikut, yaitu berjenis kelamin perempuan (77,5%), riwayat gangguan tidur (79,6%), riwayat gangguan makan (69,3%), permasalahan dengan teman (49%), riwayat mengalami perundungan (40,8%), riwayat mengalami pelecehan seksual (26,5%), riwayat gangguan mntal (26,5%), memiliki permasalahan dengan dosen (22,4%), merokok (10,2%), konsumsi alkohol (2%). Kesimpulan: Seperlima mahasiswa pernah melakukan tindakan self-injury. Terdapat berbagai faktor risiko perilaku self-injury pada mahasiswa yang perlu diperhatikan.
GAMBARAN KLINIKOPATOLOGI POLIP HIDUNG DI POLIKLINIK  THT-KL RSUP DR. M. DJAMIL TAHUN 2019-2021 Dira, Atshyfa Zsazsa; Huriyati, Effy; Rustam, Erlina; Djosan, Al Hafiz; Endrinaldi, Endrinaldi; Intan, Shinta Ayu
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 5 (2025): SINERGI : Jurnal Riset Ilmiah, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i5.1257

Abstract

Nasal polyps appear as a round, semi-transparent mass and typically develop in the middle meatus and paranasal sinuses. Histologically, nasal polyps can be divided into two subtypes, eosinophilic and neutrophilic polyps. The recurrence rate of nasal polyps is quite high, with 60-70% of patients experiencing recurrence after undergoing FESS treatment for about 18 months. The purpose of this study was to determine the clinical and histopathological characteristics of patients with nasal polyps at the THT-KL Polyclinic of Dr. M. Djamil Central Hospital in 2019-2021. This study used a descriptive design with total sampling method. The sample in this study consisted of 77 patients who met the inclusion criteria. The results of this study showed that the most frequent clinicopathological characteristics of nasal polyps in the patients were: middle-aged age group (37.66%), male gender (54.5%), sinusitis risk factor (89.61%), bilateral nature of polyps (57.14%), the most common stage was stage II (50.65%), clinical symptom of nasal congestion (98.7%), surgical management (88.31%), neutrophilic histopathological type (84.42%), with a recurrence rate of 19.48%. In conclusion, the most frequent age distribution of patients with nasal polyps was in the 41-60 age group, with the most common male gender, sinusitis risk factor, bilateral type of polyps, the most common stage was stage II, clinical symptom of nasal congestion, the most common management was surgical, histopathological type was neutrophilic, and is recurrent
The Profile of Gastrointestinal Stromal Tumors (GISTs) at Dr. M. Djamil General Hospital Padang, Indonesia: A Descriptive Study on 28 Patients Aliska, Gestina; Novianti, Hera; Angraini, Desti; Liana, Nana; Nova, Riki; Rustam, Erlina
Frontiers on Healthcare Research Vol. 1 No. 1 (2024)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v1.n1.p19-23.2024

Abstract

Background: Gastrointestinal stromal tumors (GISTs) are the most frequently seen mesenchymal neoplasm in the digestive system. GISTs was originally described as smooth muscle tumor in the 1980s but advances in molecular diagnostic methods and immunohistochemistry moved GISTs into a different category from smooth muscle tumors. The study aims to report on epidemiological, clinical, immunochemical, and therapeutic characteristics of GISTs. Methods: We performed a retrospective descriptive study of 28 cases of GIST in the gastroenterology and general surgery departments of M. Djamil General Hospital Padang, Indonesia was conducted from January 2019 to December 2021. Data collection using medical records of patients in M. Djamil General Hospital Padang, Indonesia. We reported different data: Age, sex, symptoms, site, and immunohistochemistry of the tumor.  Results: Our study included 28 patients 18 males (64,3%) and 10 females (35.7%), with a median age range of 51-60 years. The presenting symptoms were abdominal mass (53.6%), abdominal pain (14.3%), bloody or dark-colored stools (14.3%), constipation (7.1%), fatigue (7.1%), and nausea and vomiting in 1 case (3.6%). Sixteen patients (57.1%) had a primary tumor and twelve patients (42.9%) had further metastatic lesions. The tumors were found in the stomach (21.4%), small intestine (14.3%), rectum (14.3%), and in other sites such as the retroperitoneal, liver, and distal pancreas. The immunohistochemical study was performed in seven cases (expression of  CD117 and DOG1), in four cases  CD117 was positive, while in three cases CD117 was negative. In two cases, the expression of DOG1 was positive, while in one case, it was negative. Eighteen patients with GIST (64.3%) underwent surgical procedures. A combination of surgical and chemotherapy was prescribed in 9 patients (32.1%). The chemotherapy regimen prescribed is imatinib. One patient is inoperable and has received symptomatic treatment. Conclusion : In conclusion, our result showed that GISTs are highest in the male population with an age range of 51-60 years. The most common symptom of GISTs is abdominal mass. Patients who have been diagnosed with GIST by histopathological examination do not always show positive expression in the immunohistochemical study. Surgical resection was indicated in the majority of patients, and a combination of surgery and chemotherapy is also prescribed as a treatment for patients with GIST.
Co-Authors Afdal Afdal, Afdal Afriani, Nita Akmal M. Hanif Angraini, Desti Antonius, Puja Agung Arina Widya Murni Auliza Ramadona Azmira, Nazurah Beni Indra, Beni Catherina, Felicia Daan Khambri Defrin, Defrin Dessy Arisanty Dira, Atshyfa Zsazsa Djosan, Al Hafiz Effy Huriyati Elly Usman Endrinaldi Eryati Darwin Ezy Julianx Jarit Fadil Oenzil Fenty Anggrainy Gardenia Akhyar Gestina Aliska Gusti Rati Hasmiwati Helmi Arifin Hendra Permana henny Mulyani Husnil Kadri Ida Rahmah Burhan Ilmiawati, Ilmiawati Intan, Shinta Ayu Irvan Medison Julizar Julizar Julizar Julizar Katerine Katerine liana, nana Lili Irawati Lily Restusari Machdawaty Masri Magza, Dekasih Tria Mahata, Liganda Endo Melati Setia Ningsih Melita Husna Mia Puspita Mohamad Reza Mohamad Reza Muhammad Fadli Muhammad Husnul Ikhsan Muhammad Luthfi Muhammad Syauqie Nindita, Priska Audina Nova, Riki Novianti, Hera Novilla Rezka Sjahjadi Prima Astuti Handayani Rahma, Ivena Sabilla Rahmatini . Rina Gustia Rinal Effendi Rini Gusya Liza Roslaili Rasyid Saptino Miro, Saptino Suchitra, Avit Sukri Rahman Syahrul, Muhammad Zulfadli Syilfana, Hanifah Valencia Perdana Rizal Yaslinda Yaunin Yobi Syumarta Yulistini Yusri, Elfira Yusticia Katar Zafira, Qory