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All Journal Medika Tadulako Journal of Islamic Pharmacy Preventif: Jurnal Kesehatan Masyarakat Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung Jurnal Ilmu Kefarmasian Indonesia Pharmaceutical Journal of Indonesia Pharmacoscript Health Information : Jurnal Penelitian Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Pharmaceutical Sciences and Research (PSR) Sciences of Pharmacy
Yusi Anggriani
University of Pancasila, Srengseng Sawah Jagakarsa, Jakarta, Indonesia
Aerospace Engineering Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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The role of pharmacist counseling for patient with type 2 diabetes mellitus and its impact on blood glucose control and quality of life at RSUD Pasar Minggu Hardi, Devita; Anggriani, Yusi; Purba, Fredrick Dermawan
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1685

Abstract

Quality of life is an important aspect for patients with type 2 diabetes mellitus (T2DM). Pharmacist counseling is a non-pharmacological effort that can be provided to improve quality of life and control blood glucose levels. This study aimed to determine the effect of pharmacist-led therapeutic counseling for T2DM patients on improving their quality of life and reducing blood glucose levels. The study used a quasi-experimental nonequivalent control group design, with pretest and posttest assessments conducted before and after the intervention at RSUD Pasar Minggu, South Jakarta. A total of 194 T2DM patients participated in the study, with 97 patients in both the intervention and control groups. Quality of life was measured using the EQ-5D-5L and EQ-VAS questionnaires, along with fasting blood glucose levels. Measurements were taken three times: before the intervention, and one month and two months after the intervention. Paired data were analyzed using the Wilcoxon test, while unpaired data were analyzed using the Mann-Whitney test at a significance level of 0.05. Counseling significantly improved EQ-5D-5L scores (Δ=0.06; p<0.001) and EQ-VAS scores (Δ=6.40; p<0.001), as well as reduced fasting blood glucose levels (Δ=-12.10 mg/dL; p<0.001) in the intervention group after the intervention. The impact of counseling was particularly significant in the pain/discomfort and anxiety/depression domains. However, no significant correlation was found between quality of life and fasting blood glucose levels in this study (p>0.05). Pharmacist counseling conducted at RSUD Pasar Minggu had a positive and significant impact on improving the quality of life and treatment outcomes related to blood glucose reduction.
Evaluasi Penggunaan Antibiotik dengan Metode Kuantitatif pada Pasien Pneumonia Rawat Inap di Rumah Sakit Nusa Tenggara Barat Khairani, Sondang; Ramadaniati, Hesty Utami; Sarnianto, Prih; Kristin, Erna; Anggriani, Yusi
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1449

Abstract

Abstract Overuse of antibiotics is a public health challenge that can lead to antimicrobial resistance. To reduce the occurrence of antibiotic resistance, it is necessary to evaluate the use of antibiotics to determine the rational use of drugs using quantitative methods, namely the ATC /DD method. The purpose of the study was to determine the use of antibiotics and describe the pattern of antibiotic use in inpatients at West Nusa Tenggara Hospital using the ATC /DD method and DU90%. The research method is a cross-sectional study design with retrospective data collection on adult pneumonia patients hospitalized in the period Januari-December 2019 and 2022, data obtained from medical records. The results of the study met the inclusion criteria of 218 patients with the majority being male 117 (53.67%) and the most age > 65, namely 66 (30.28%). Antibiotic use has a total DDD value of 185.56 DDD/100 days of care with the highest antibiotic DDD value being ceftriaxone which is 104.00 DDD/100 days of hospitalization while antibiotics that are included in the DU 90% are ceftriaxone, levofloxacin, cefoperazon and meropenem. Conclusion the most antibiotics used were ceftriaxone 104.00 DDD/100 days of length of stay.
PENGARUH PELAYANAN HOME CARE APOTEKER PADA PENGETAHUAN, KEPATUHAN, KUALITAS HIDUP, DAN OUTCOME KLINIS PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS KOTA TANGERANG Fitriana, Irna; Utami R, Hesty; Anggriani, Yusi; Yuliani
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1556

Abstract

Pelayanan kefarmasian yang berfokus pada pasien, khususnya home pharmacy care, menekankan penerapan edukasi melalui home care oleh apoteker sebagai pendekatan untuk memodifikasi perilaku hidup pasien. Penelitian ini bertujuan untuk menginvestigasi dampak pelayanan home care apoteker terhadap pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis pada pasien diabetes melitus tipe 2. Penelitian dilaksanakan di Puskesmas Neglasari (kelompok intervensi) dan Puskesmas Bugel (kelompok kontrol) selama periode tiga bulan dengan desain quasi eksperimental menggunakan two group pretest-posttest. Sampel penelitian dipilih melalui metode total sampling, melibatkan 100 pasien diabetes melitus tipe 2 (51 dalam kelompok intervensi dan 49 dalam kelompok kontrol). Instrumen penelitian berupa Kuesioner ADL knowledge, kuesioner Medication Adherence Report Scale (MARS) dan Kuesioner Short form-36 (SF-36). Pada tahap awal penelitian, uji Chi-Square menunjukkan bahwa tidak ada perbedaan signifikan dalam karakteristik demografi dan profil klinis antara kedua kelompok, dengan nilai p p-value >0,005. Setelah intervensi home care, uji Chi-Square pada kelompok intervensi mengindikasikan perubahan yang signifikan sebelum dan sesudah pemberian home care terkait pengetahuan (p=0,000), tingkat pengetahuan menggunakan dua metode MARS-5 (p=0,003) dan pill count (p=0,005), kualitas hidup (p=0,000), serta hasil klinis (p=0,013). Sementara pada kelompok kontrol, tidak terdapat perbedaan yang signifikan sebelum dan sesudah penelitian, dengan nilai p-value >0,005. Uji Mann-Whitney menunjukkan perbedaan signifikan pada hasil posttest terkait pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis antara kedua kelompok (p=0,000*). Uji korelasi dengan Spearman’s rho menegaskan adanya hubungan antara pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis (sig=0,000). Kesimpulan dari penelitian ini adalah bahwa pelayanan home care yang disediakan oleh apoteker efektif dalam memperbaiki seluruh aspek variabel yang menjadi fokus penelitian.
DAMPAK PENERAPAN KEBIJAKAN E-CATALOGUE TAHUN 2023 TERHADAP POLA PENGADAAN OBAT DI RSUD dr. DRADJAT PRAWIRANEGARA: IMPACT OF 2023 E-CATALOGUE POLICY ON DRUG PROCUREMENT PATTERNS AT RSUD dr. DRADJAT PRAWIRANEGARA Junaedi, Candra; Anggriani, Yusi; Abillah, Syamsudin; Sari, Ratna Permana
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/zra0nq53

Abstract

Pengadaan obat di rumah sakit merupakan aspek penting dalam menjamin kelancaran pelayanan kesehatan kepada masyarakat. Dengan kemajuan teknologi dan regulasi pemerintah, pengadaan obat kini dilakukan secara menyeluruh melalui sistem e-Purchasing menggunakan e-Catalogue. Penelitian ini bertujuan mengevaluasi pengadaan obat e-Catalogue dan non e-Catalogue sebelum dan sesudah penerapan kebijakan e-Catalogue tahun 2023 di RSUD dr. Dradjat Prawiranegara Serang. Penelitian ini menggunakan pendekatan observasional analitik dengan data retrospektif tahun 2022-2023. Data obat e-Catalogue diperoleh dari LKPP dan obat non e-Catalogue dari SIMRS. Analisis dilakukan secara univariat dengan metode deskriptif yang ditampilkan pada gambar dan tabel. Hasil menunjukkan bahwa secara keseluruhan pengadaan obat melalui e-Catalogue pada tahun 2023 meningkat dan pengadaan non e-Catalogue menurun. Sedangkan pengadaan obat generik meningkat dari 66,62% menjadi 70,20% dan pengadaan obat non e-Catalogue nama dagang meningkat dari 51,81% menjadi 64,67%. Waktu tunggu pengadaan obat e-Catalogue pada tahun 2023 tercatat lebih lama, yaitu sekitar 103 hari, dibandingkan obat non e-Catalogue sekitar 17 hari. Namun, waktu tunggu obat e-Catalogue pada 2023 lebih cepat dibandingkan tahun 2022 yang mencapai 121 hari. Terdapat delapan penolakan obat (50% karena persediaan, 25% syarat minimum, 12,5% harga, 12,5% negosiasi). Kesimpulan pengadaan obat e-Catalogue dan non e-Catalogue periode 2022-2023 dipengaruhi oleh implementasi kebijakan pengadaan obat tahun 2023
Analisis Efektivitas Biaya Pengobatan Kombinasi Zidovudin, Lamivudin, Nevirapin dan Kombinasi Tenofovir, Lamivudin, Efavirenz Pada Pasien HIV/AIDS di RSUD Kota Bekasi: COST EFFECTIVENESS ANALYSIS OF ZIDOVUDIN, LAMIVUDIN, NEVIRAPIN (AZT (300)/3TC (150) / NVP (200)) AND TENOFOVIR, LAMIVUDIN, EFAVIRENZ (TDF (300) / 3TC (150) / 3TC (150) / NVP (200)) AND TENOFOVIR, LAMIVUDIN, EFAVIRENZ (TDF (300) / 3TC (150) / 3TC (150) / NVP (200)) / AIDS IN BEKASI HOSPITAL Anggriani, Yusi; Purba, Fredrick Dermawan; Manninda, Reise; Tarsinah, Tarsinah
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 18 No. 2 (2020): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.905

Abstract

HIV/AIDS has become a global issue in many countries. The implementation of ARV / HAARTprograms is always changing, due to clinical reasons, population factors, and aff ordability. Pharmacoeconomic studies can be one of the considerations in the policy process for procurement and selection of therapy regimens. The aims of this study were to determine the eff ectiveness of treatment based on CD4 increase and cost eff ectiveness analysis of HAART A and HAART B treatment regimens. This study used a cross sectional observation method. Retrospective data collection and non-experimental observation where conducted followes by a quantitative descriptive analysis according to the patient's perspective to obtain costeffectiveness data. Data were statistically analyzed to obtain the cost-eff ectiveness of treatment. The results showed that the cost-eff ectiveness analysis (CEA) of two regimens found that HAART A was more dominant than HAART B with a signifi cant diff erence p<0.05. While ACER regimen HAART A (16,227) was greater than the value ACER therapy B (28,330.7).
The role of pharmacist counseling for patient with type 2 diabetes mellitus and its impact on blood glucose control and quality of life at RSUD Pasar Minggu Hardi, Devita; Anggriani, Yusi; Purba, Fredrick Dermawan
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1685

Abstract

Quality of life is an important aspect for patients with type 2 diabetes mellitus (T2DM). Pharmacist counseling is a non-pharmacological effort that can be provided to improve quality of life and control blood glucose levels. This study aimed to determine the effect of pharmacist-led therapeutic counseling for T2DM patients on improving their quality of life and reducing blood glucose levels. The study used a quasi-experimental nonequivalent control group design, with pretest and posttest assessments conducted before and after the intervention at RSUD Pasar Minggu, South Jakarta. A total of 194 T2DM patients participated in the study, with 97 patients in both the intervention and control groups. Quality of life was measured using the EQ-5D-5L and EQ-VAS questionnaires, along with fasting blood glucose levels. Measurements were taken three times: before the intervention, and one month and two months after the intervention. Paired data were analyzed using the Wilcoxon test, while unpaired data were analyzed using the Mann-Whitney test at a significance level of 0.05. Counseling significantly improved EQ-5D-5L scores (Δ=0.06; p<0.001) and EQ-VAS scores (Δ=6.40; p<0.001), as well as reduced fasting blood glucose levels (Δ=-12.10 mg/dL; p<0.001) in the intervention group after the intervention. The impact of counseling was particularly significant in the pain/discomfort and anxiety/depression domains. However, no significant correlation was found between quality of life and fasting blood glucose levels in this study (p>0.05). Pharmacist counseling conducted at RSUD Pasar Minggu had a positive and significant impact on improving the quality of life and treatment outcomes related to blood glucose reduction.
Cost-Effectiveness Analysis of Carboplatin-Paclitaxel, Cisplatin-Pemetrexed, and Carboplatin-Gemcitabine Chemotherapy Regimens in Patients with Non-Small Cell Lung Cancer at Persahabatan Central General Hospital Melinda, Venni; Anggriani, Yusi; Khairani, Sondang; Nurhayati, Fitri
Sciences of Pharmacy Volume 5 Issue 3 (2026)
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0502685

Abstract

Platinum-based chemotherapy remains an important treatment option for patients with advanced non-small cell lung cancer (NSCLC), particularly in settings where reimbursement and resource allocation are major considerations. A retrospective observational cost-effectiveness study was conducted using medical records and billing data from adult patients with NSCLC who received carboplatin–paclitaxel, cisplatin–pemetrexed, or carboplatin–gemcitabine in 2023. Effectiveness outcomes included the one-year survival rate (%) and median progression-free survival (PFS). Costs were calculated based on direct medical expenses over six chemotherapy cycles. Cost-effectiveness was assessed using ACER, ICER, and dominance analysis. A total of 101 patients were included: 81 received carboplatin and paclitaxel, 14 received cisplatin and pemetrexed, and 6 received carboplatin and gemcitabine. Mean direct medical costs were IDR 27,588,547, IDR 41,214,281, and IDR 47,471,752, respectively. No statistically significant differences were observed in one-year survival rate or median PFS among the regimens, although interpretation should consider the unequal sample sizes (81 vs. 14 vs. 6), which limit statistical power. Based on one-year survival, carboplatin–paclitaxel had the lowest ACER and dominated the other regimens by providing higher observed survival at lower cost. Based on median PFS, cisplatin–pemetrexed provided longer PFS than carboplatin–paclitaxel but at a higher cost, requiring ICER-based interpretation. Carboplatin–paclitaxel was associated with the lowest direct medical cost and the most favorable cost-effectiveness profile based on one-year survival among the evaluated regimens. However, conclusions should be interpreted cautiously because of the retrospective design, small and unequal group sizes, and potential confounding by baseline clinical characteristics.
Co-Authors Abillah, Syamsudin Ahriansyah, Andi Andalucia, Rizka Annisa, Rifka Aritonang, MGS Ath-Thobari, Jarir Banun, Agusdini Candra Junaedi Chaerul Y, Ricky Dian Ratih Laksmitawati Dwi Puspita Sari, Dwi Puspita Elisna Syahruddin Erna Kristin Evy Yunihastuti Fitri Nurhayati Fitriana, Irna Fredrick Dermawan Purba Hardi, Devita Harissa, Nola Ilham Maulana Jayati, Turpuk Mannaria L, Dian Ratih Mayasari, Yeshi Melinda, Venni Mita Restinia Mulatsari, Esti Nanang Erlana Pontoan, Jenny Pratiwi, Annisa Nadya R, Hesty Utami Ramadaniati, Hesty Utami Reise Manninda Retnaningrum, Dyah Rianti, Alfina Rosanti, Ade Rosiana, Rosiana S.Farm., M.Farm., Apt, Sondang Khairani Sabirin, Briliana Sahat Saragi Sahat Saragih Sari, Ratna Permana Sarnianto, Prih Sarnianto, Prih Sarwono Waspadji Septa, Tendry Siti Aisyah Suratni Suratni Tanty, Herty Nur Tarsinah, Tarsinah Tri Kusumaeni, Hesty Utami R. Utami R, Hesty Wijaya, Rulliani Bianca Wulan Puspitasari Y, Ricky Chaerul Yani, Dosi Ahmad Yava Rony, Devi Yazid, Ricky Chaerul Yulia Trisna, Yulia YULIANI