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All Journal Medika Tadulako Journal of Islamic Pharmacy Preventif: Jurnal Kesehatan Masyarakat Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung Jurnal Ilmu Kefarmasian Indonesia Pharmaceutical Journal of Indonesia Pharmacoscript Health Information : Jurnal Penelitian Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Pharmaceutical Sciences and Research (PSR) Sciences of Pharmacy Eduvest - Journal of Universal Studies
Yusi Anggriani
University of Pancasila, Srengseng Sawah Jagakarsa, Jakarta, Indonesia
Aerospace Engineering Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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The role of pharmacist counseling for patient with type 2 diabetes mellitus and its impact on blood glucose control and quality of life at RSUD Pasar Minggu Hardi, Devita; Anggriani, Yusi; Purba, Fredrick Dermawan
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1685

Abstract

Quality of life is an important aspect for patients with type 2 diabetes mellitus (T2DM). Pharmacist counseling is a non-pharmacological effort that can be provided to improve quality of life and control blood glucose levels. This study aimed to determine the effect of pharmacist-led therapeutic counseling for T2DM patients on improving their quality of life and reducing blood glucose levels. The study used a quasi-experimental nonequivalent control group design, with pretest and posttest assessments conducted before and after the intervention at RSUD Pasar Minggu, South Jakarta. A total of 194 T2DM patients participated in the study, with 97 patients in both the intervention and control groups. Quality of life was measured using the EQ-5D-5L and EQ-VAS questionnaires, along with fasting blood glucose levels. Measurements were taken three times: before the intervention, and one month and two months after the intervention. Paired data were analyzed using the Wilcoxon test, while unpaired data were analyzed using the Mann-Whitney test at a significance level of 0.05. Counseling significantly improved EQ-5D-5L scores (Δ=0.06; p<0.001) and EQ-VAS scores (Δ=6.40; p<0.001), as well as reduced fasting blood glucose levels (Δ=-12.10 mg/dL; p<0.001) in the intervention group after the intervention. The impact of counseling was particularly significant in the pain/discomfort and anxiety/depression domains. However, no significant correlation was found between quality of life and fasting blood glucose levels in this study (p>0.05). Pharmacist counseling conducted at RSUD Pasar Minggu had a positive and significant impact on improving the quality of life and treatment outcomes related to blood glucose reduction.
Evaluasi Penggunaan Antibiotik dengan Metode Kuantitatif pada Pasien Pneumonia Rawat Inap di Rumah Sakit Nusa Tenggara Barat Khairani, Sondang; Ramadaniati, Hesty Utami; Sarnianto, Prih; Kristin, Erna; Anggriani, Yusi
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1449

Abstract

Abstract Overuse of antibiotics is a public health challenge that can lead to antimicrobial resistance. To reduce the occurrence of antibiotic resistance, it is necessary to evaluate the use of antibiotics to determine the rational use of drugs using quantitative methods, namely the ATC /DD method. The purpose of the study was to determine the use of antibiotics and describe the pattern of antibiotic use in inpatients at West Nusa Tenggara Hospital using the ATC /DD method and DU90%. The research method is a cross-sectional study design with retrospective data collection on adult pneumonia patients hospitalized in the period Januari-December 2019 and 2022, data obtained from medical records. The results of the study met the inclusion criteria of 218 patients with the majority being male 117 (53.67%) and the most age > 65, namely 66 (30.28%). Antibiotic use has a total DDD value of 185.56 DDD/100 days of care with the highest antibiotic DDD value being ceftriaxone which is 104.00 DDD/100 days of hospitalization while antibiotics that are included in the DU 90% are ceftriaxone, levofloxacin, cefoperazon and meropenem. Conclusion the most antibiotics used were ceftriaxone 104.00 DDD/100 days of length of stay.
PENGARUH PELAYANAN HOME CARE APOTEKER PADA PENGETAHUAN, KEPATUHAN, KUALITAS HIDUP, DAN OUTCOME KLINIS PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS KOTA TANGERANG Fitriana, Irna; Utami R, Hesty; Anggriani, Yusi; Yuliani
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1556

Abstract

Pelayanan kefarmasian yang berfokus pada pasien, khususnya home pharmacy care, menekankan penerapan edukasi melalui home care oleh apoteker sebagai pendekatan untuk memodifikasi perilaku hidup pasien. Penelitian ini bertujuan untuk menginvestigasi dampak pelayanan home care apoteker terhadap pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis pada pasien diabetes melitus tipe 2. Penelitian dilaksanakan di Puskesmas Neglasari (kelompok intervensi) dan Puskesmas Bugel (kelompok kontrol) selama periode tiga bulan dengan desain quasi eksperimental menggunakan two group pretest-posttest. Sampel penelitian dipilih melalui metode total sampling, melibatkan 100 pasien diabetes melitus tipe 2 (51 dalam kelompok intervensi dan 49 dalam kelompok kontrol). Instrumen penelitian berupa Kuesioner ADL knowledge, kuesioner Medication Adherence Report Scale (MARS) dan Kuesioner Short form-36 (SF-36). Pada tahap awal penelitian, uji Chi-Square menunjukkan bahwa tidak ada perbedaan signifikan dalam karakteristik demografi dan profil klinis antara kedua kelompok, dengan nilai p p-value >0,005. Setelah intervensi home care, uji Chi-Square pada kelompok intervensi mengindikasikan perubahan yang signifikan sebelum dan sesudah pemberian home care terkait pengetahuan (p=0,000), tingkat pengetahuan menggunakan dua metode MARS-5 (p=0,003) dan pill count (p=0,005), kualitas hidup (p=0,000), serta hasil klinis (p=0,013). Sementara pada kelompok kontrol, tidak terdapat perbedaan yang signifikan sebelum dan sesudah penelitian, dengan nilai p-value >0,005. Uji Mann-Whitney menunjukkan perbedaan signifikan pada hasil posttest terkait pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis antara kedua kelompok (p=0,000*). Uji korelasi dengan Spearman’s rho menegaskan adanya hubungan antara pengetahuan, tingkat kepatuhan, kualitas hidup, dan hasil klinis (sig=0,000). Kesimpulan dari penelitian ini adalah bahwa pelayanan home care yang disediakan oleh apoteker efektif dalam memperbaiki seluruh aspek variabel yang menjadi fokus penelitian.
Cost Analysis and Treatment of Covid-19 Patients with Comorbidities at Rspad Gatot Soebroto Togarma, Petrus Kabul; Anggriani, Yusi; Utami R, Hesty; Andari K, Dewiyana
Eduvest - Journal of Universal Studies Vol. 4 No. 9 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i9.3794

Abstract

The COVID-19 pandemic has significantly affected the global health sector, especially in patients with comorbidities such as type-2 diabetes mellitus and hypertension. Patients with these comorbidities require special attention and proper handling during the COVID-19 treatment process, given the higher risk of complications in this group. Gatot Soebroto Army Hospital, as a referral center for COVID-19 in Indonesia, faces the complexity of handling patients who often have complicated clinical conditions which are also related to the costs required. Therefore, analyzing the cost and treatment of COVID-19 patients who also suffer from comorbidities such as hypertension, type-2 diabetes mellitus, type-2 diabetes mellitus and hypertension is essential to improve care management. This study took place from January to July 2021 at Gatot Soebroto Army Hospital. The purpose of the study was to determine the cost and treatment of COVID-19 and the relationship between severity and outcomes. The method used was retrospective observational in COVID-19 patients with these comorbidities. The results showed that the largest cost expenditure came from room and accommodation costs. The highest average total cost came from a combination of comorbid hypertension and type-2 DM. The frequently used treatment profile showed antiviral therapy (favipirapir), antibiotics (Levofloxacin and Azithromycin), anticoagulants (heparin), corticosteroids (dexamethasone), and symptomatic (paracetamol). Improvement in clinical condition was the highest clinical outcome. The result of Chi-Square test analysis between severity and clinical outcome was significant (p-value 0.007<0.05). In conclusion, the treatment profile is adjusted to the clinical condition and the severity of COVID-19 affecting the clinical outcome.
Quality and Potency of Government-subsidized Antibiotics in Hospitals Across Jakarta, Indonesia Khairani, Sondang; Ramadaniati, Hesty Utami; Sarnianto, Prih; Kristin, Erna; Anggriani, Yusi
Sciences of Pharmacy Volume 3 Issue 1
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0301198

Abstract

Several pharmaceutical companies have long complained that the price of medicines that win the e-catalogue tender is too low, in some cases even below the cost of production. However, it should not be a concern that only pharmaceutical products with regulation of Indonesian food and drug (BPOM) distribution licenses are eligible for the price tender, as they are of good quality. This study aims to determine the quality and potency of three antibiotic drugs based on their highest utilization (DU 90%) in pneumonia patients at two hospitals, A (ceftriaxone, azithromycin tablet) and B (ceftriaxone, levofloxacin infusion) compared to brand name. The quality of the samples was evaluated following the Indonesian Pharmacopoeia 6th Edition (FI-VI). Antibiotic potency was assessed using the Plate-Cylinder Method with K. pneumonia from human and S. pneumonia ATCC 10015 as the test bacteria evaluated following CLSI. All samples meet the criteria of FI-VI antibiotic content, weight uniformity, dissolution. Antibiotic potency all samples test S.pneumonia and K.pneumonia were sensitive but ceftriaxone test with K.pneumonia was resistance. All antibiotic tablets and injections studied met the requirements of the Indonesian Pharmacopoeia Edition 6 for active medicinal ingredient content, dosage weight uniformity, and dissolution. All drugs from hospitals (INN) have lower antibiotic potency than branded drugs. This highlight the importance of conducting microbiological testing on antibiotic preparations.
DAMPAK PENERAPAN KEBIJAKAN E-CATALOGUE TAHUN 2023 TERHADAP POLA PENGADAAN OBAT DI RSUD dr. DRADJAT PRAWIRANEGARA: IMPACT OF 2023 E-CATALOGUE POLICY ON DRUG PROCUREMENT PATTERNS AT RSUD dr. DRADJAT PRAWIRANEGARA Junaedi, Candra; Anggriani, Yusi; Abillah, Syamsudin; Sari, Ratna Permana
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/zra0nq53

Abstract

Pengadaan obat di rumah sakit merupakan aspek penting dalam menjamin kelancaran pelayanan kesehatan kepada masyarakat. Dengan kemajuan teknologi dan regulasi pemerintah, pengadaan obat kini dilakukan secara menyeluruh melalui sistem e-Purchasing menggunakan e-Catalogue. Penelitian ini bertujuan mengevaluasi pengadaan obat e-Catalogue dan non e-Catalogue sebelum dan sesudah penerapan kebijakan e-Catalogue tahun 2023 di RSUD dr. Dradjat Prawiranegara Serang. Penelitian ini menggunakan pendekatan observasional analitik dengan data retrospektif tahun 2022-2023. Data obat e-Catalogue diperoleh dari LKPP dan obat non e-Catalogue dari SIMRS. Analisis dilakukan secara univariat dengan metode deskriptif yang ditampilkan pada gambar dan tabel. Hasil menunjukkan bahwa secara keseluruhan pengadaan obat melalui e-Catalogue pada tahun 2023 meningkat dan pengadaan non e-Catalogue menurun. Sedangkan pengadaan obat generik meningkat dari 66,62% menjadi 70,20% dan pengadaan obat non e-Catalogue nama dagang meningkat dari 51,81% menjadi 64,67%. Waktu tunggu pengadaan obat e-Catalogue pada tahun 2023 tercatat lebih lama, yaitu sekitar 103 hari, dibandingkan obat non e-Catalogue sekitar 17 hari. Namun, waktu tunggu obat e-Catalogue pada 2023 lebih cepat dibandingkan tahun 2022 yang mencapai 121 hari. Terdapat delapan penolakan obat (50% karena persediaan, 25% syarat minimum, 12,5% harga, 12,5% negosiasi). Kesimpulan pengadaan obat e-Catalogue dan non e-Catalogue periode 2022-2023 dipengaruhi oleh implementasi kebijakan pengadaan obat tahun 2023
Analisis Efektivitas Biaya Pengobatan Kombinasi Zidovudin, Lamivudin, Nevirapin dan Kombinasi Tenofovir, Lamivudin, Efavirenz Pada Pasien HIV/AIDS di RSUD Kota Bekasi: COST EFFECTIVENESS ANALYSIS OF ZIDOVUDIN, LAMIVUDIN, NEVIRAPIN (AZT (300)/3TC (150) / NVP (200)) AND TENOFOVIR, LAMIVUDIN, EFAVIRENZ (TDF (300) / 3TC (150) / 3TC (150) / NVP (200)) AND TENOFOVIR, LAMIVUDIN, EFAVIRENZ (TDF (300) / 3TC (150) / 3TC (150) / NVP (200)) / AIDS IN BEKASI HOSPITAL Anggriani, Yusi; Purba, Fredrick Dermawan; Manninda, Reise; Tarsinah, Tarsinah
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 18 No. 2 (2020): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.905

Abstract

HIV/AIDS has become a global issue in many countries. The implementation of ARV / HAARTprograms is always changing, due to clinical reasons, population factors, and aff ordability. Pharmacoeconomic studies can be one of the considerations in the policy process for procurement and selection of therapy regimens. The aims of this study were to determine the eff ectiveness of treatment based on CD4 increase and cost eff ectiveness analysis of HAART A and HAART B treatment regimens. This study used a cross sectional observation method. Retrospective data collection and non-experimental observation where conducted followes by a quantitative descriptive analysis according to the patient's perspective to obtain costeffectiveness data. Data were statistically analyzed to obtain the cost-eff ectiveness of treatment. The results showed that the cost-eff ectiveness analysis (CEA) of two regimens found that HAART A was more dominant than HAART B with a signifi cant diff erence p<0.05. While ACER regimen HAART A (16,227) was greater than the value ACER therapy B (28,330.7).
The role of pharmacist counseling for patient with type 2 diabetes mellitus and its impact on blood glucose control and quality of life at RSUD Pasar Minggu Hardi, Devita; Anggriani, Yusi; Purba, Fredrick Dermawan
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1685

Abstract

Quality of life is an important aspect for patients with type 2 diabetes mellitus (T2DM). Pharmacist counseling is a non-pharmacological effort that can be provided to improve quality of life and control blood glucose levels. This study aimed to determine the effect of pharmacist-led therapeutic counseling for T2DM patients on improving their quality of life and reducing blood glucose levels. The study used a quasi-experimental nonequivalent control group design, with pretest and posttest assessments conducted before and after the intervention at RSUD Pasar Minggu, South Jakarta. A total of 194 T2DM patients participated in the study, with 97 patients in both the intervention and control groups. Quality of life was measured using the EQ-5D-5L and EQ-VAS questionnaires, along with fasting blood glucose levels. Measurements were taken three times: before the intervention, and one month and two months after the intervention. Paired data were analyzed using the Wilcoxon test, while unpaired data were analyzed using the Mann-Whitney test at a significance level of 0.05. Counseling significantly improved EQ-5D-5L scores (Δ=0.06; p<0.001) and EQ-VAS scores (Δ=6.40; p<0.001), as well as reduced fasting blood glucose levels (Δ=-12.10 mg/dL; p<0.001) in the intervention group after the intervention. The impact of counseling was particularly significant in the pain/discomfort and anxiety/depression domains. However, no significant correlation was found between quality of life and fasting blood glucose levels in this study (p>0.05). Pharmacist counseling conducted at RSUD Pasar Minggu had a positive and significant impact on improving the quality of life and treatment outcomes related to blood glucose reduction.
PENGARUH PROLANIS TERHADAP OUTCOME KLINIK PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS KECAMATAN PULOGADUNG Tanty, Herty Nur; Anggriani, Yusi; Saragi, Sahat
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 6 No. 1 (2019)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v6i1.2978

Abstract

Prolanis merupakan program dari PT. Askes (Persero) dalam upaya penanganan penyakit kronis pada pasien DM tipe 2. Jumlah pasien DM yang tergabung di Prolanis setiap tahunnya terus bertambah akan tetapi tidak disertai dengan kontinuitas kunjungan. Berdasarkan data jumlah peserta prolanis DM tipe 2 di Puskesmas Kecamatan Pulogadung yang sudah mengikuti prolanis minimal 6 bulan sejumlah 284 pasien. Tujuan penelitian ini adalah untuk mendapatkan perbedaan outcome klinik pasien prolanis dibanding pasien non prolanis dan mendapatkan hubungan antara kepatuhan dengan outcome klinik. Penelitian ini menggunakan desain cross sectional dengan alur penelitian retrospektif sebelum dan sesudah pasien bergabung dengan prolanis. Data diperoleh dari rekam medik dan data kunjungan pasien dengan menggunakan teknik total sampling. Hasil penelitian menunjukkan adanya perbedaan outcome klinik pasien DM tipe 2 yang mengikuti prolanis dengan pasien DM tipe 2 yang tidak mengikuti prolanis (p<0,05). Hasil penelitian menunjukkan adanya hubungan antara tingkat kepatuhan kunjungan dengan outcome klinik pasien prolanis dan non prolanis (p<0.05).
Outcome Klinik Berdasarkan Pemilihan Jenis Insulin pada Pasien Diabetes Mellitus Tipe 2 yuliasari, ida; Anggriani, Yusi; Utami R, Hesty
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 9 No. 2 (2022)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v9i2.6931

Abstract

Penggunaan insulin mengalami perubahan dimana insulin analog meningkat sedangkan insulin manusia mengalami penurunan. Hal ini perlu dikaji mengingat harga insulin analog lebih tinggi sehingga berdampak pada kenaikan biaya dan menyebabkan keterbatasan dalam penggunaannya yang akhirnya berdampak pada hasil terapi. Tujuan penelitian ini adalah untuk mengetahui pola penggunaan insulin dan outcome kliniknya. Penelitian dilakukan secara longitudinal time series dari data retrospektif  yang meliputi data pasien, data obat dan data pemeriksaan laboratorium. Jumlah sampel sebanyak 86 pasien terdiri dari 28 pasien pengguna insulin manusia dan 56 pasien pengguna insulin analog. Outcome klinik yang dianalisa adalah GDP, GDPP, dan HbA1C yang dinilai berdasarkan kategori terkendali baik, terkendali sedang dan terkendali buruk. Outcome klinik dianalisis dengan uji normalitas Kolmogorov Smirnov, selanjutnya dilakukan uji komparatif statistik non parametrik Kruskal Wallis dan uji Mann Whitney untuk melihat signifikansi perbedaan antar kategori. Insulin analog yang paling banyak digunakan adalah insulin analog tunggal. Hasil analisis menunjukkan tidak ditemukan perbedaan outcome klinik dari penggunaan insulin analog dan insulin manusia pada nilai GDP, GDPP dan HbA1C.
Co-Authors Abillah, Syamsudin Ahriansyah, Andi Andalucia, Rizka Andari K, Dewiyana Annisa, Rifka Aritonang, MGS Ath-Thobari, Jarir Banun, Agusdini Chaerul Y, Ricky Dian Ratih Laksmitawati Dwi Puspita Sari, Dwi Puspita Elisna Syahruddin Erna Kristin Evy Yunihastuti Fitri Nurhayati Fitriana, Irna Fredrick Dermawan Purba Hardi, Devita Harissa, Nola Ilham Maulana Jayati, Turpuk Mannaria Junaedi, Candra L, Dian Ratih Mayasari, Yeshi Mita Restinia Mulatsari, Esti Nanang Erlana Pontoan, Jenny Pratiwi, Annisa Nadya R, Hesty Utami Ramadaniati, Hesty Utami Reise Manninda Retnaningrum, Dyah Rianti, Alfina Rosanti, Ade Rosiana, Rosiana S.Farm., M.Farm., Apt, Sondang Khairani Sabirin, Briliana Sahat Saragih Saragi, Sahat Sari, Ratna Permana Sarnianto, Prih Sarnianto, Prih Sarwono Waspadji Septa, Tendry Siti Aisyah Suratni Suratni Tanty, Herty Nur Tarsinah, Tarsinah Togarma, Petrus Kabul Tri Kusumaeni, Hesty Utami R. Utami R, Hesty Wijaya, Rulliani Bianca Wulan Puspitasari Y, Ricky Chaerul Yani, Dosi Ahmad Yava Rony, Devi Yazid, Ricky Chaerul Yulia Trisna, Yulia YULIANI yuliasari, ida