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All Journal Jurnal Sains Materi Indonesia Indonesian Journal of Tropical and Infectious Disease MEDISAINS Dental Journal (Majalah Kedokteran Gigi) Indonesian Journal of Chemistry Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Layanan Masyarakat (Journal of Public Service) Indian Journal of Forensic Medicine & Toxicology Indonesian Community Journal Prosiding Seminar Nasional Unimus JURNAL REKAYASA KIMIA & LINGKUNGAN Folia Medica Indonesiana
Prihartini Widiyanti
Biomedical Engineering Study Program, Department Of Physics, Faculty Of Science And Technology, Universitas Airlangga Institute Of Tropical Disease, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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In Vitro Characterization of Poly(Ethylene Glycol) Dimethacrylate-Nanofibrillated Cellulose as an Injectable Biomaterial for Herniated Nucleus Pulposus Substitute Widiyanti, Prihartini; Firda, Yurituna; , Aminatun; Wibowo, Herry
Folia Medica Indonesiana Vol. 60, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: 1. Novel synthetic biopolymer hydrogels were successfully prepared from pristine poly(ethylene glycol) dimethacrylate (PEGDMA) and nanofibrillated cellulose (NFC) using the photopolymerization method. 2. PEGDMA-NFC biocomposite hydrogel can be developed as an affordable biomaterial for herniated nucleus pulposus substitute, with the potential to meet clinical application standards. Abstract Herniated nucleus pulposus develops when the intervertebral disc portudes through the annulus fibrosus due to the rupture of the annulus fibrosus or a decrease in proteoglycans. Hydrogel implant material can be injected into the disc space to restore disc thickness caused by disc degeneration with minimal invasiveness. This study aimed to characterize poly(ethylene glycol) dimethacrylate-nanofibrillated cellulose (PEGDMA-NFC) in vitro as a potential biomaterial for herniated nucleus pulposus substitute. This study utilized PEGDMA-NFC to treat first-degree herniated nucleus pulposus using the photopolymerization method. PEGDMA was selected because of its hydrophilic ability to produce hydrogel. The addition of NFC to the PEGDMA precursor was expected to show mechanical properties as a hydrogel bio composite candidate. The characterization of PEGDMA-NFC was conducted using three tests: Fourier-transform infrared spectroscopy (FTIR), viscosity assessment, and an in vitro injection testing model. The normal distribution of the data was analyzed using the Kolmogorov-Smirnov test, while the homogeneity was assessed using Levene's test. Homogenous and normally distributed data were analyzed using a one-way analysis of variance (ANOVA) with a p-value of <0.05. The explored concentrations of PEGDMA-NFC included a ratio of 1:0 for the control samples and ratios of 1:0.5 (K1), 1:0.75 (K2), and 1:1 (K3) for the experimental samples. The FTIR analysis revealed the presence of various functional groups in PEGDMA-NFC, indicating its potential classification as a hydrogel biomaterial. The characterization data showed that the K3 sample yielded the most favourable outcome with a viscosity value of 74.67 dPa·s. From the in vitro injection testing result, the addition of NFC demonstrated that the hydrogel would not rupture when released from the mold. The hydrogel could be injected with an 18 gauge needle. The statistical analysis results showed a significant difference among the samples (p<0.05). This study concludes that the PEGDMA-NFC hydrogel biocomposite can be effectively applied in herniated nucleus pulposus cases.
Pengembangan Industri Terakota di Desa Jatipasar Trowulan sebagai Upaya Pelestarian Budaya dan Pemberdayaan Ekonomi Masyarakat Prihartini Widiyanti; Ikhsan Rosyid Mujahidul Anwari; Usma Nur Dian Rosyidah; Sigit Ari Saputro
I-Com: Indonesian Community Journal Vol 5 No 1 (2025): I-Com: Indonesian Community Journal (Maret 2025)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70609/icom.v5i1.6736

Abstract

Jatipasar Village in Trowulan is one of the areas that inherited the cultural treasures of Majapahit with cultural heritage in the form of temples, the heritage of terracotta craft motifs. The architectural characteristics of Majapahit became the hallmark of terracotta. Currently in Trowulan alone there are only 5 terracotta craftsmen who exist and 3 from Jatipasar. The terracotta industry has high cultural value and significant economic potential. This community service activity aims to develop the terracotta industry through a one-day seminar workshop method so as to provide knowledge for craftsmen and people who are interested in becoming terracotta craftsmen. The activity was attended by 12 residents consisting of craftsmen and residents with resource person Arif Suharson from ISI Yogyakarta, who provided material on terracotta techniques and marketing. The pre-test and post-test methods were used to measure participants' understanding before and after the activity. The results of this activity showed an increase in participants' understanding of the terracotta industry, as well as contributing to cultural preservation and community economic empowerment.
Robusta Coffe-Derived Silver Nanoparticles as a Natural Photosensitizer for Photodynamic Inactivation of Bacterial Biofilms Amruloh, Yazid Muhammad; Astuti, Suryani Dyah; Arifianto, Deny; Nurdin, Dezy Zahrotul Istiqomah; Zaidan, Andi Hamim; Widiyanti, Prihartini; Yaqubi, Ahmad Khalil; Winarno; Abd Razak, Nasrul Anuar
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 3 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i3.74709

Abstract

Bacterial biofilm formation represents a major challenge in clinical settings, as it contributes to persistent infections and resistance to conventional antimicrobial treatments. This study investigates the effectiveness of blue laser therapy combined with AgNPs-CR in inhibiting biofilm formation by Escherichia coli and Staphylococcus aureus, common infection agents, in a four-group sample set. Silver nanoparticles, known for their antibacterial, antifungal, and antiviral properties, are widely used in biomedical devices. First, the control group (T0) included samples without laser irradiation. Second, the Escherichia coli and Staphylococcus aureus groups (A1 and A2) were irradiated with a 405 nm diode laser at various exposure times and silver nanoparticle concentrations. Third, the E. coli and S. aureus groups (A3 and A4) were also irradiated with the 405 nm diode laser under varying durations and concentrations of silver nanoparticles. In groups A2 and A4, the bacteria were treated with the photosensitizer AgNPs-CR, incubated for 30 minutes, and then irradiated for 90, 120, 150, and 180 seconds. The results were analyzed using a two-way factorial ANOVA and a Post-hoc Tukey test, with a significance level of p < 0.05. Photodynamic therapy (PDT) significantly inhibited bacterial biofilms in samples with irradiation, with the most significant reduction observed at a concentration of 2 mM and 180 seconds of irradiation, compared to samples without irradiation. Staphylococcus aureus was the most susceptible to AgNPs, showing a high biofilm inhibition percentage of 94.82% at 180 seconds of irradiation with a 2 mM concentration. Fluorescence microscope analysis revealed the presence of bacterial DNA corresponding to 180 colonies.
Penguatan Kapasitas Kader Posyandu Melalui Pemanfaatan Stunting Kit dan Nurse Kit di Desa Wisata Hendrosari Qulub, Fitriyatul; Rahma, Osmalina Nur; Widiyanti, Prihartini; Nizam, Abiyyu; Janice, Theresia; Yael RBS, Jeanny; Kharisman H, Fourdes; Thevan Y, Georgeous
I-Com: Indonesian Community Journal Vol 5 No 4 (2025): I-Com: Indonesian Community Journal (Desember 2025)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70609/i-com.v5i4.8325

Abstract

Desa Hendrosari masih menghadapi tantangan kesehatan, terutama risiko stunting yang belum sepenuhnya terkendali, keterbatasan keterampilan kader dalam memantau tumbuh kembang anak, serta pencatatan layanan kesehatan yang masih manual sehingga sering menyulitkan proses pengambilan keputusan. Program pengabdian masyarakat ini bertujuan memperkuat kapasitas kader Posyandu dan Pokja KB melalui peningkatan pemahaman gizi pada 1.000 HPK, pelatihan pertolongan pertama, serta pemanfaatan Stunting Kit dan Nurse Kit sebagai alat bantu pemantauan kesehatan yang lebih akurat. Kegiatan dilaksanakan dengan pendekatan partisipatif melalui tahapan koordinasi, sosialisasi, pelatihan, pendampingan, dan evaluasi bersama mitra desa. Hasil menunjukkan peningkatan pengetahuan dan kepercayaan diri kader dalam menggunakan alat kesehatan dan memberikan layanan dasar yang lebih responsif. Antusiasme masyarakat turut memperkuat keberhasilan kegiatan. Program ini memberi dampak nyata dalam meningkatkan literasi kesehatan, memperbaiki kualitas layanan Posyandu, dan mendorong terbentuknya ekosistem Desa Hendrosari sebagai desa wisata sehat yang berkelanjutan.
Co-Authors , Aminatun - Aminatun - Siswanto Abd Razak, Nasrul Anuar Achmad Ardianto, Achmad Adanti Wido Paramadini Adiana Mutamsari Witaningrum Adiana Mutamsari, Adiana Adri Supardi Agung Prabowo Agung Prabowo Ahmad Fadli Ahmad Fadli Akfiny Hasdi Aimon Akhmad Jayadi Alfian Pramudita Putra Aminatun Amma, Fadli Amruloh, Yazid Muhammad Andi Hamim Zaidan Anggraini Barlian Anika Rahma Putri Arie Wibowo Arifianto, Deny Azizia Kanya Fathiarachman Bambang Prajogo Baskoro, Andhi Bella Wahyu Sukma Wati Bimo Aksono Bimo Dwi Lukito, Bimo Dwi Bramantono Bramantono, Bramantono Budi Utomo Chandra Satria Arisgraha, Franky Cindy Narita Kusuma Astuti Deni Noviana Desi Sandrasari Dio Nurdin Setiawan, Dio Nurdin Dita Ayu Mayasari, Dita Ayu Djony Izak Rudyardjo Dwiyanti, Tasya Amalia Dyar Sasmito, Dyar Eko Budi Kuntjoro, Eko Budi Endah Purwanti Eprilina, Alifiani Ernie Maduratna Setiawatie Fathan Aditya Sanjaya Fathiarachman, Azizia Kanya Fatkhunisa Rahmawati, Fatkhunisa Fa’ilal Chusna Fendy Purwanda, Fendy Ferdiansyah Ferdiansyah Firda, Yurituna Fitriyatul Qulub Franky Arisgraha, Franky Franky Chandra Satria Arisgraha Hafrizal Riza, Hafrizal Hariyono Hariyono Hariyono Helmi Majid Ar Rasyid Heni Ismawati Heri Purnobasuki, Heri Herry Wibowo Herry Wibowo Ikhsan Rosyid Mujahidul Anwari Indrio, Ludita Woro Isfandiary, Andini Ismawati, Heni Jabbar, Hajria Jan Ady Jan Ady Janice, Theresia Julieta Kartikasari Juniastuti Juniastuti Kharisman H, Fourdes Khoirunnisa Suhandarini Kholifatul Wanda Putri, Kholifatul Wanda Khusnul Ain Kirana Anugerah Putri Lambang Bargowo M. Qushay, M. Maria Inge Lusida Maulida, Hendita Nur Mirzaq Hussein Anwar, Mirzaq Hussein Muhammad Bagas Ananda Muhammad Vitanata Arfijanto, Muhammad Vitanata Nabila Safira Khairina Nasronudin Nasronudin Nastiti, Helena Putri Ni Putu Ermi Hikmawati, Ni Putu Ermi Nilna Faizah Fiddarain, Nilna Faizah Nizam, Abiyyu Nur Rahma, Osmalina Nurdin, Dezy Zahrotul Istiqomah Osmalina Nur Rahma Pramudita, Alfian Putri, Anika Rahma Putri, Dina Kartika Radicha Arnanda Putri Indrawati Rehman, Saifur Retna Apsari Retno Indrawati Roestamadji Retno Pudji Rahayu Retno puji Rahayu Rihandhita Shinta Meiliana Riries Rulaningtyas Rozykulyyeva, Lale Sari, Gadis Meinar Satrio Adhitioso Savitri, Irma Yosephina Sherina Pradita Eka Wahyudi Shifa Fauziyah Shifa Fauziyah Sigit Ari Saputro Siswanto Siswanto Siswanto Siti Irma Mashitah, Siti Irma Siti Qamariyah Khairunisa, Siti Qamariyah Siti Qomariyah Khairunisa, Siti Qomariyah Solly Aryza Suhandarini, Khoirunnisa Suryani Dyah Astuti Tami Bachrurozy Tarissa Diandra Putri Wibowo Tasya Amalia Dwiyanti Teguh Hari Sucipto, Teguh Hari Thevan Y, Georgeous Tjahjono, Ganis Tomohiro Kotaki, Tomohiro Tri Arif Sardjono, Tri Arif Tria Refi Indriani Usma Nur Dian Rosyidah Veren Audia Nurmansya Wardhani, Inten Firdhausi Wibowo, Herry Wijayanti, Tia Rahayu WINARNO Wulandari Prima Devi Yael RBS, Jeanny Yaqubi, Ahmad Khalil Yufan Fibriawan, Yufan Yurituna Firda