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All Journal Journal of Food and Pharmaceutical Science Jurnal Ilmiah Farmasi Jurnal Farmasi Udayana MEDISAINS AJIE (Asian Journal of Innovation and Entrepreneurship) JURNAL PHARMASCIENCE Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) INDONESIAN JOURNAL OF PHARMACY Pharmascience Journal of Islamic Pharmacy Jurnal Farmasi Sains dan Komunitas Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) CHEESA: Chemical Engineering Research Articles JSFK (Jurnal Sains Farmasi & Klinis) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Abdimas Madani dan Lestari (JAMALI) Jurnal Ners Medfarm: Jurnal Farmasi dan Kesehatan Journal of Pharmaceutical and Health Research Hydrogen: Jurnal Kependidikan Kimia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Khazanah: Jurnal Mahasiswa Eduvest - Journal of Universal Studies Journal of Food and Pharmaceutical Sciences Parapemikir Jurnal Ilmiah Farmasi Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Lutfi Chabib, Lutfi
Department Of Pharmacy, Islamic University Of Indonesia
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Journal : Journal of Islamic Pharmacy

 1 
Formulasi Gel Hand Sanitizer Ekstrak Buah Belimbing Wuluh dengan Variasi Karbopol 940 dan HPMC Ferdy Firmansyah; Hastri Kholifah; Lutfi Chabib
Journal of Islamic Pharmacy Vol 7, No 1 (2022): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v7i1.13839

Abstract

The hand hygiene is compulsory to keep maintain. It is one of the important things to prevent the diseases that caused by microorganisms infection or the other infectious diseases, especially during this COVID-19 pandemic. Most of the hand sanitizer (HS) products are used alcohol as an antibacterial. The right way to reduce the use of HS-containing alcohol is by replacing them with using the active substances derived from herbal plant extracts, one of it is the star fruit (BBW). Flavonoid is one of the component in BBW. Thus, the purpose of this study is to determine the effect of a good combination of Carbopol 940 base and HPMC on the physical properties of HS BBW gel preparations. The formulation of hand sanitizer gel was used a combination of Carbopol 940 and HPMC with the variation concentrations of 0.5%; 0.75%; 1% and 0.25%; 0.5%; 0.75%. Evaluation of the physical properties of the gel preparation was determined based on the observations of consistency, scent, colour, pH, homogeneity, dispersibility, and physical stability using the freeze and thaw method for 6 storage cycles at 4°C and 45°C. The results shown that the variations concentration of gelling agents affect pH and dispersion. The higher the concentration of the gelling agent, the lower pH value and dispersion. This can be seen in each formula in the first week with pH 6.31, 6.13, and 5.62, and spreadability of 6.2, 5.8, and 5.6. Tests on the fourth week in a row with pH of 5.53, 5.49, and 5.23 and a spread of 5.2, 5.0, and 4.5. Variations in the concentration of HPMC and Carbopol was not affected to the organoleptic, homogeneity, and also the stability.
Co-Authors Achmad Fachrodji Agenilia Permatasari Aghna Mafruha Zahrah, Aghna Mafruha Agus Santosa Agustina Setiawati Aji Winanta Akhmad Fauzy Akhmad Nabil Akhmad Nabil, Akhmad Ali Djamhuri Anggara Setyabawana Putra Annisa, Viviane Aprianto . Aprianto Aprianto Arba Pramundita Arba Pramundita Ramadani Arifa Caryn Dea Utami Hasyono Arismunandar, Arif Asih Triastuti Baharuddin Yusuf Baharudin Yusuf Baruna, Renno Ramadhani Ika Cermenda, Riska Cynthia Astiti Putri Dewi, Melynia Sintha Dimas Adhi Pradana Dzihni Meytasari Farah Deastasa Nabilah Ferdy Firmansyah Gandhi Barajana Vedha Gani, Michael Raharja Gelu, Maria Andriani Guanse, Yovi Hady Anshory Hamzah, Hasyrul Hanida Destriana Fatmawati Hani’atul Kharimah Hannie Fitriani Hasnaeni hasnaeni, Hasnaeni Hastri Kholifah Hayati, Farida Herman Felani Hilda Ismail, Hilda Ipaenin, Jahiria Jenita Gandi, Brigita Tuelvin Kamarulzaman, Ezatul Ezleen Kholidah, Ziyyatul Kinanti, Valentina Putri Embun Lumakso, Fajar Aji M. Pandoman febrian Maemonah, Maemonah Martien, Ronny Maulana Ardhi Mimiek Murrukmihadi Mufrod Mufrod Muh Iqbal Pangestu Muhammad Faisal Muhammad Ikhwan Rizki Muhammad Iqbal Pangestu Muhammad Safarullah Muhtadi, Wildan Khairi Muslim, M. Rifqi Fadillah Mutiara Herawati, Mutiara Muzakir, Mellisa Nurul Afifi Lobubun Oktavia Indrati, Oktavia Prima Aulia Putra Reihan Khairiati Renno Ramadhani Ika Baruna Ria Cahya Andriana Rini Dwiastuti Ririn Wulandari Rischi Dwi Irianti Rischi Dwi Irianti, Rischi Dwi Rizki Awaluddin Rizqi, Syifa Maulidia Rochmy Istikharah Ronny Martien Ronny Martien Samsul Hadi Siti Zahliyatul Munawiroh Suryani, Arman Syarif Hidayatullah Taufikurrahmi Taufikurrahmi Trianloka, A. M. Bagas Tunny, Risman Uzulul Hikmah Wahyu, Imron Yandi Syukri Yosi Febrianti, Yosi Ziyyatul Kholidah