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All Journal HAYATI Journal of Biosciences ILMU KELAUTAN: Indonesian Journal of Marine Sciences Jurnal Ilmu Kedokteran (Journal of Medical Science) BIOTROPIA - The Southeast Asian Journal of Tropical Biology Perspektif : Review Penelitian Tanaman Industri Indonesian Journal of Pharmaceutical Science and Technology Indonesian Journal of Biotechnology Elkawnie Majalah Obat Tradisional Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Acta Pharmaceutica Indonesia JSFK (Jurnal Sains Farmasi & Klinis) JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Farmasi Indonesia Perspektif, Review Penelitian Tanaman Industri Current Research on Biosciences and Biotechnology Nusantara Hasana Journal Archives Pharmacia Proceeding of Mulawarman Pharmaceuticals Conferences Scientific Journal Journal of Applied Agricultural Science and Technology Jurnal Farmasi Sains dan Praktis Jurnal Natural Riset Informasi Kesehatan AGRIC Jurnal Pengabdian Masyarakat Kesehatan (JURABDIKES) Borneo Journal of Pharmacy Kartika : Jurnal Ilmiah Farmasi Journal of Tropical Pharmacy and Chemistry Greensusmater Agroscript: Journal of Applied Agricultural Sciences
Elfahmi Elfahmi, Elfahmi
School of Pharmacy, Bandung Institute of Technology
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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PANDANGAN PESERTA BPJS DI KELURAHAN AIR PACAH TERHADAP PEMBERHENTIAN PELAYANAN BPJS DI RUMAH SAKIT ISLAM SITI RAHMAH TAHUN 2020 Rika Amran; Elfahmi, Elfahmi; Adji Mustiaji; Pratiwi Ramadhani Feriza
Nusantara Hasana Journal Vol. 3 No. 7 (2023): Nusantara Hasana Journal, December 2023
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v3i7.1293

Abstract

Social Security Administration Agency (BPJS) is a legal entity established to organize social security programs. BPJS collaborates with hospitals in order to improve service quality and health service quality. One of the hospitals that have collaborated with BPJS is RSI Siti Rahmah, which is located in Air Pacah Village, Padang. Termination of cooperation between BPJS and RSI Siti Rahmah at the end of 2019 will have an impact on the continuity of BPJS participants in Air Pacah village.The purpose of this study was to determine the views of BPJS participants in Air Pacah Village on the stop of BPJS services at RSI Siti Rahmah in 2020. The method used in this study was descriptive observation through open interviews without any intervention to the respondents. There were 10 respondents involved in this study who were BPJS participants and resisded in Air Pacah sub-district. BPJS participants in Air Pacah sub-district were disappointed with the discontinuation of BPJS services at RSI Siti Rahmah. The respondents had to find another hospital with BPJS services that farther that before. As conclusion the people are disappointed and need the nearest health facility for treatment.
Uji Aktivitas Antidiabetes Produk Obat Herbal yang Mengandung Ekstrak Bratawali (Tinospora crispa (L.) Miers ex Hoff.f & Thoms.) Elfahmi, Elfahmi; Santoso, Winny; Anggardiredja, Kusnandar
JSFK (Jurnal Sains Farmasi & Klinis) Vol 6 No 3 (2019): J Sains Farm Klin 6(3), Desember 2019
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.6.3.213-219.2019

Abstract

Berdasarkan data WHO pada tahun 2019 lebih dari 463 juta orang di dunia menderita diabetes, dan cenderung jumlahnya semakin meningkat. Dengan bertambahnya penderita diabetes menyebabkan penggunaan obat antidiabetes meningkat. Berbagai macam obat diabetes telah digunakan untuk mengobati penyakit ini, diantaranya penggunaan obat herbal. Salah satu tumbuhan obat yang berkhasiat sebagai penurun kadar gula darah adalah bratawali (Tinospora crispa). Tujuan penelitian adalah menguji aktivitas antidiabetes produk obat herbal kategori jamu yang diproduksi oleh usaha mikro obat tradisional (UMOT) yang mengandung bratawali. Aktivitas antiabetes diuji dengan menggunakan metode toleransi glukosa dan efek pada mencit diabetes imbasan aloksan. Hasil pengujian kualitas menunjukkan ekstrak mengandung senyawa golongan alkaloid, flavonoid, dan steroid/triterpenoid. Pengujian aktivitas antidiabetes menunjukkan ekstrak dapat menghambat kenaikan kadar glukosa pada uji toleransi glukosa sebesar 18,29; 51,17 dan 75,35 % (p<0,05) dengan dosis berturut-turut 125, 250 dan 500 mg/kgBB. Sementara itu, pada mencit diabetes imbasan aloksan ekstrak mampu menurunkan kadar glukosa darah dengan penurunan yang terbesar 75,35% (p < 0,05) setelah pemberian dosis 500 mg/kgBB. Dari data yang diperoleh dapat disimpulkan bahwa ekstrak dari produk obat herbal yang mengandung bratawali sebagai komponen aktif mempunyai aktivitas antidiabetes. Senyawa aktif pada ekstrak bratawali yang bertanggung jawab untuk aktivitas tersebut masih perlu ditentukan.
Karakteristik Pasien Abses Leher Dalam Di Bangsal THT RSUD M.Natsir 2020-2023 Tri Yuspita Sari , Jenny; Elfahmi
Scientific Journal Vol. 3 No. 5 (2024): SCIENA Volume III No 5, September 2024
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v3i5.170

Abstract

Abses leher dalam merupakan akumulasi pus di ruang potensial antara fasia superfisial dan profunda leher dalam yang terjadi akibat penjalaran infeksi seperti infeksi pada gigi, saluran napas, dan telinga tengah. Jumlah kasus ini di Indonesia masih belum diketahui secara pasti, tetapi riwayat infeksi gigi masih menjadi pencetus terbanyak insiden abses leher dalam. Laporan kasus wanita 62 tahun datang dengan keluhan utama benjolan pada dagu kiri sejak 14 hari yang lalu. Benjolan berawal dari dagu kiri, lalu meluas ke pipi hingga leher kanan-kiri disertai dengan nyeri. Pasien memiliki riwayat sakit gigi bagian rahang kiri bawah. Pemeriksaan rongga mulut didapatkan kebersihan oral yang buruk dan beberapa gigi berlubang. Pemeriksaan kepala leher didapatkan udem pada pipi kiri, fluktuatif, dan kulit tampak nekrotik. Submandibula udem dan fluktuatif. Coli anterior kanan-kiri tampak udem dan terdapat fistula kutan yang mengeluarkan pus. Diagnosis awal medis yaitu abses submandibula, abses bukal, abses coli superficial dengan fistula kutan. Gigi molar kedua dan ketiga kiri bawah merupakan sumber infeksi bagi abses leher dalam, karena akarnya meluas ke persimpangan otot milohioid dengan korpus mandibula yang berdekatan dengan ruang submandibula dan parafaring, membuat ruang submandibula menjadi area yang paling sering terdampak dalam kasus ini.
Challenges in Molecular and Morphological Identification of Sponge Species in Raja Ampat Aisyah, Siti Zanuba; Zamani, Neviaty Putri; Cahyani, Ni Kadek Dita; Elfahmi, Elfahmi; Syafrizayanti, Syafrizayanti; Andriani, Yosie; Arafat, Dondy; Bashari, Muhammad Hasan; Hanif, Novriyandi; Sani, Lalu M. Iqbal; Ayu, Inna Puspa; Akbar, Nebuchadnezzar; Subhan, Beginer
ILMU KELAUTAN: Indonesian Journal of Marine Sciences Vol 30, No 1 (2025): Ilmu Kelautan
Publisher : Marine Science Department Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/ik.ijms.30.1.115-125

Abstract

Sponges (Phylum Porifera) are a group of highly diverse, sessile, and filter-feeding basal metazoans, except spongillids. The majority of sponges are marine species that play an important role in benthic habitat by maintaining the stability of marine ecosystems through nutrient cycling, habitat provision, and bioerosion. However, marine sponges are not easily identifiable because of their lack of species-level distinctive morphological features, which limits efforts to monitor actual species biodiversity. Indonesia is home to approximately 850 identified species of marine sponges, and Raja Ampat archipelago of West Papua province is known for its exceptional marine biodiversity. Despite the species abundance, the exact number of sponges in the region is not well-documented due to the lack of specific studies providing comprehensive data on their diversity. Therefore, this study aimed to conduct a DNA barcoding analysis using the mitochondrial cytochrome oxidase I (COI) gene as a marker, combined with morphological analyses of 22 individuals collected in the waters of Waigeo, Mansuar, and Gam Islands in Raja Ampat. The results showed that 3 samples were identified at the species level (Halichondria sp. and Stylissa carteri) with good query cover and percent identity. This showed the possible presence of undescribed or cryptic species, suggesting a severe lack of reference data for both morphology and molecular analyses of marine sponges in the region. Consequently, the analysis showed the presence of a significant gap in the understanding of sponge biodiversity in Raja Ampat's waters.
Pemberian Informasi & Edukasi “Peranan Patologi Anatomi pada Kanker Payudara” Morawati, Soufni; Elfahmi; Yuspita Sari, Jenny Tri; Yasa, Yanti Fitri
Abdika Sciena Vol 2 No 2 (2024): JURABDIKES Volume 2 No 2, Desember 2024
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/jurabdikes.v2i2.182

Abstract

Patologi anatomi memiliki peranan penting dalam diagnosis, prognosis, dan pemilihan terapi kanker payudara. Pemeriksaan patologi anatomi, seperti biopsi dan analisis histopatologi, membantu menentukan jenis, stadium, serta karakteristik molekuler kanker payudara, yang berpengaruh terhadap strategi pengobatan yang tepat. Namun, pemahaman masyarakat mengenai pentingnya patologi anatomi dalam deteksi dan penanganan kanker payudara masih terbatas. Kegiatan ini bertujuan untuk memberikan informasi dan edukasi mengenai peranan patologi anatomi dalam kanker payudara serta mengevaluasi dampaknya terhadap pemahaman masyarakat. Metode yang digunakan meliputi seminar kesehatan, distribusi materi edukatif melalui media cetak dan digital, serta diskusi interaktif dengan tenaga medis. Evaluasi dilakukan dengan membandingkan tingkat pemahaman peserta sebelum dan sesudah intervensi edukasi. Hasil kegiatan menunjukkan bahwa pemberian informasi dan edukasi secara signifikan meningkatkan pemahaman peserta mengenai pentingnya pemeriksaan patologi anatomi dalam diagnosis dan pengobatan kanker payudara. Sebagian besar peserta menjadi lebih sadar akan pentingnya deteksi dini dan pemeriksaan histopatologi untuk menentukan terapi yang optimal. Dengan demikian, edukasi mengenai peranan patologi anatomi dapat menjadi strategi efektif dalam meningkatkan kesadaran masyarakat terhadap pentingnya diagnosis yang akurat dalam penanganan kanker payudara.
Piper cubeba L. f. Nanoemulsion: Formulation and Effect on Antioxidant Activity in Rat's Hippocampus and Prefrontal Cortex Dwita, Lusi Putri; Iwo, Maria Immaculata; Mauludin, Rachmat; Elfahmi, Elfahmi
Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i2.8720

Abstract

The previous study showed that Piper cubeba extract increased brain antioxidant capacity, alleviating cognitive impairment in rats. However, brain-targeted drug delivery is often limited by the blood-brain barrier. One of the approaches to overcome this obstacle is nanocarrier. This study aimed to formulate a nanoemulsion (NE) of P. cubeba extract and determine the antioxidant activity in the brain. The research begins with the determination of excipients and the formula of NE. The formula was then tested for globule size, polydispersity index, thermodynamic stability, zeta potential, pH, and viscosity. The globule's shape was determined using transmission electron microscopy (TEM). The antioxidant activity was tested by catalase and lipid peroxidase activity in the brain after giving NE orally for seven days. Formulations of NE resulted in nano-size globules and were stable thermodynamically. The NE formula significantly increased catalase and inhibited lipid peroxidase activities in the Rat's hippocampus and prefrontal cortex. This study resulted in a stable formula and low-cost production of P. cubeba extract NE, which is active as the brain's antioxidant and is feasible to develop as a neuroprotective agent for various neurodegenerative diseases.
PHYTOCHEMICAL STUDY OF CELL CULTURE JATROPHA CURCAS ELFAHMI, ELFAHMI; ARTRI; RUSLAN, KOMAR
BIOTROPIA Vol. 18 No. 1 (2011): BIOTROPIA Vol. 18 No. 1 June 2011
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11598/btb.2011.18.1.137

Abstract

Jatropha curcas belongs to the Euphorbiaceae family which has potential economically. This plant has been reported to contain toxic compounds such as curcin and phorbol ester and its derivatives. These compounds may become a problem if J. curcas will be explored as a source of biofuel. In order to provide safety plants, the research on the study of phytochemical and initiation of cell and organ culture have been carried out. J curcas which has been collected from different regions in Indonesia showed to contain relatively the same profile of chemical contents. Dominant compounds that were detected by GCMS are hidrocarbon such as  2-heptenal, decadienal, hexsadecane, pentadecane, cyclooctane etc, fatty acid such as oktadecanoate acid, etthyl linoleate, ethyl stearate, heksadecanoate acid and steroid such as stigmasterol, fucosterol, sitosterol. No phorbol ester and its derivatives have been detected yet by the GCMS method. Callus and suspension cultures of J. curcas have been established to be used for further investigation.   Keywords: Jatropha curcas, phytochemical, biofuel, cell culture, steroid, hydrocarbon, fatty acid
Cross-linking formation of taro starch (colocasia esculenta)-based hydrogel using freeze-thaw method: synthesis and physical characterization Luthfianti, Halida Rahmi; Nafisah, Nuraini; Waresindo, William Xaveriano; Sawitri, Asti; Hapidin, Dian Ahmad; Noor, Fatimah Arofiati; Elfahmi, Elfahmi; Edikresnha, Dhewa; Khairurrijal, Khairurrijal
Greensusmater Vol. 2 No. 2 (2025)
Publisher : Green and Sustainable Materials Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62755/greensusmater.2025.2.2.36-48

Abstract

This study successfully made starch from taro tuber flour using immersion methods (AQ, SM) and centrifugation methods (CE). Taro starch with the AQ method produced the most starch content, thus improving the viscosity parameter in the pasting properties test. A simple mathematical model was used to control the taro starch pasting process and product. The highest R-value in the AQ sample was 309.88 s, indicating the strongest starch granule resistance. Meanwhile, the S-value in this study showed that all samples were above 1, which indicated that water penetration affected the swelling rate of starch granules. Taro starch with different isolation methods was analyzed for hydrogel formation using optical microscopy, SEM, swelling degree test, weight loss, color analysis, and texture profile analysis (TPA). The morphological images show three phases of a taro starch hydrogel formation: granular, potential cross-linking, and cross-linking hydrogel with a firm structure. Optimization of freeze-thaw process parameters was carried out to determine the optimum parameters of starch hydrogel formation, which was obtained under freezing conditions for 17 hours at -23°C and thawing for 7 hours at 4°C. The sample CE resulted in the most stable hydrogel formation, showing the highest amylose content, protein content, and the lowest impurities or ash content. The CE starch concentration of 10% resulted in the highest swelling degree and the lowest weight loss, indicating that the ability of the hydrogel to maintain its structure was stronger and more elastic. The textural properties of CE hydrogel at a concentration of 10% showed the most stability. It had the highest hardness, fracturability, chewiness, and springiness. Physical characteristics showed that the starch hydrogels had a dense, porous surface and formed a cross-linking structure. It can potentially be used in functional food applications to control the release of bioactive compounds. 
Comparative Efficacy of Phaseolus aureus Extract and Synthetic Growth Regulators on Callus Induction in Curcuma xanthorrhiza Faramayuda, Fahrauk; Melani, Putri Dwi; Elfahmi, Elfahmi
AGROSCRIPT: Journal of Applied Agricultural Sciences Vol 7 No 2 (2025): December
Publisher : Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/agroscript.v7i2.2392

Abstract

Temulawak (Curcuma xanthorrhiza Roxb) a plant indigenous to Indonesia, is increasingly recognized for its medicinal properties, formulating a cornerstone of traditional medicine with annual usage marking a significant growth rate of approximately 5.4%. As awareness of its therapeutic potential expands, too does the demand for this valuable resource, necessitating enhanced efforts in its propagation and the extraction of its bioactive compounds. This study investigates the efficacy of different growth regulators in the induction of callus tissue from C. xanthorrhiza through plant tissue culture, a key method for regenerating valuable plant material. Specifically, the research focuses on the comparative effects of natural growth regulators, particularly water extracts from Phaseolus aureus, and synthetic growth regulators such as 2,4-Dichlorophenoxyacetic Acid (2,4-D) and Indole-3-butyric Acid (IBA) in varied concentrations. The experimental design included varying concentrations of P. aureus water extract at 10%, and 15%, alongside a fixed concentration of the synthetic agents. Findings indicated that synthetic growth regulators, particularly the combination of 2,4-D and IBA at a concentration of 0.4 ppm each, yielded superior callus proliferation compared to the natural extract treatments. However, P. aureus aqueous extract showed positive effects also on callus emergence and on increasing explant size when used at 10% concentration in Murashige-Skoog medium. Consequently, the study underscores the potential of integrating both natural and synthetic growth regulators to enhance callus induction and ultimately facilitate the sustainable use of C. xanthorrhiza as a medicinal resource.
Co-Authors Adella Shindy Pratiwi Adji Mustiaji Agus Chahyadi Agus Chahyadi Agus Chahyadi Agus Supriadi Aisyah, Siti Zanuba Akbar Dana Akhirul Kahfi Syam Ana Indrayati Andi Rifki Rosandy Andre Ditya Maulana Lubis Andreanus A Soemardji Anggardiredja, Kusnandar Anita K Ari Sr Windyaswari Ari Sri Widyaswari Ari Sri Windyaswari Ari Sri Windyaswari, Ari Sri Ariranur Haniffadli ARTRI Astrid Indalifiany Ayu, Inna Puspa Bashari, Muhammad Hasan Beginer Subhan Budipramana, Krisyanti Choirul Huda Dana, Akbar DEBBIE SOEFIE RETNONINGRUM Desyane, Heipy Ketrin Dondy Arafat Edikresnha, Dhewa FAHRAUK FARAMAYUDA Fahrauk Faramayuda Fahrauk Faramayuda, Fahrauk Fany Mutia Cahyani Fatimah Arofiati Noor Fitri Yasa, Yanti Frangky Sangande Ghozaly, Muchammad Reza Hapidin, Dian Ahmad Heipy Ketrin Desyane Jaka Permana Khairunisa Harizqi Nurul Husna Khairunnisa Sy Khairurrijal khairurrijal Komar Ruslan Komar Ruslan Wirasutisna Komar Ruslan Wirasutisna Komar Ruslan Wirasutisna Kusnandar Anggardiredja Laode M.R. Al Muqarrabun Laode M.R. Al Muqarrabun Lusi Putri Dwita Luthfianti, Halida Rahmi Manalu, Meilina Marsinta Maria Immaculata Iwo Maria Immaculata Iwo Maria Immaculata Iwo MARLIA SINGGIH WIBOWO Marlia Singgih Wibowo Marlin Megalestin Raunsai Meilina Marsinta Manalu Melani, Putri Dwi Morawati, Soufni Muamar Abdillah Nabila K Nafisah, Nuraini Nebuchadnezzar Akbar NEVIATY PUTRI ZAMANI Ni Kadek Dita Cahyani, Ni Kadek Dita Niken Tunjung Murti Pratiwi Novriyandi Hanif Nurinanda Prisky Qomaladewi Nurul Nadiah Binti Abdul Rahman Oktiyas Muzaky Luthfi Pratiwi Ramadhani Feriza Rachmat Mauludin Ramelan, Riska Sigit RENALDI OKTAVIANUS Retno Wahyuningrum Retno Wahyuningrum Ridzka Magfirah Rika Amran Rika Hartati Riska Sigit Ramelan Rissyelly Rissyelly Rozida Khalid Sahidin Sahidin Salsabila, Syefira Sani, Lalu M. Iqbal Santoso, Winny Sartika Yuniarti Sawitri, Asti Shinta Maulida Rosandhy Sigid Pamungkas Wicaksono Silvy Julian Soemardji AA Sony Suhandono SONY SUHANDONO Sony Suhandono Soraya Riyanti Soraya Riyanti Sufyan Zainul Arifin Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sulistiarini, Riski Sultan Salahudin Jamal Sumirtapura, Yeyet Cahyati Syafrizayanti, Syafrizayanti Syaikhul Aziz Tan MI Tati Kristanti TATI KRISTIANTI Tina Rostinawati Totik Sri Mariani Totik Sri Mariani Totik Sri Mariani Totik Sri Mariani Tri Septiana, Vina Tri Yuspita Sari , Jenny Tri Yuspita, Jenny Waresindo, William Xaveriano Weni Widy Astuti Winny Santoso Wirasutisna, Komar Ruslan Wirasutisna, Komar Ruslan Wiwin Herdwiani Yasa, Yanti Fitri Yeni Karlina Yodha, Agung Wibawa Mahatva Yolazenia Yolazenia Yolisa Fitri, Vioni Yosie Andriani Yuspita Sari, Jenny Tri Zaini Alfahmi