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Rigid Esophagoscopy for an Impacted Kaffir Lime in the Proximal Esophagus: A Case Report and Discussion of a Unique Mechanical-Chemical Injury Rita Risandi; Ade Asyari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 10 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i10.1407

Background: Esophageal food bolus impaction is a common otolaryngological emergency. However, impaction by a large, whole citrus fruit is exceedingly rare and presents unique diagnostic and therapeutic challenges, particularly concerning the object's size, radiolucency, and potential for causing both mechanical and chemical mucosal injury. Case presentation: We present the case of a 42-year-old male with acute-onset dysphagia and hypersalivation after ingesting a whole kaffir lime. Laryngoscopy revealed pooled secretions in the pyriform sinus, a key indicator of high esophageal obstruction, despite non-contributory plain radiography. The patient underwent emergent rigid esophagoscopy under general anesthesia. A 36 mm kaffir lime was identified at 15 cm from the incisors and successfully extracted en bloc using alligator grasping forceps. Post-extraction evaluation revealed localized mucosal excoriation without evidence of deep laceration or perforation. The patient recovered fully with no long-term sequelae. Conclusion: This case highlights the successful management of a rare and challenging esophageal foreign body. It underscores the diagnostic primacy of clinical findings over negative radiography for radiolucent objects and demonstrates the distinct advantages of rigid esophagoscopy—superior airway control, a wider operating channel, and use of robust instrumentation—for large, solid foreign bodies lodged in the proximal esophagus. In this instance, the impaction did not lead to severe complications within 24 hours, but prompt removal is essential to mitigate the risks of pressure necrosis and chemical esophagitis.

Rigid Esophagoscopy for an Impacted Kaffir Lime in the Proximal Esophagus: A Case Report and Discussion of a Unique Mechanical-Chemical Injury Rita Risandi; Ade Asyari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 10 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i10.1407

Background: Esophageal food bolus impaction is a common otolaryngological emergency. However, impaction by a large, whole citrus fruit is exceedingly rare and presents unique diagnostic and therapeutic challenges, particularly concerning the object's size, radiolucency, and potential for causing both mechanical and chemical mucosal injury. Case presentation: We present the case of a 42-year-old male with acute-onset dysphagia and hypersalivation after ingesting a whole kaffir lime. Laryngoscopy revealed pooled secretions in the pyriform sinus, a key indicator of high esophageal obstruction, despite non-contributory plain radiography. The patient underwent emergent rigid esophagoscopy under general anesthesia. A 36 mm kaffir lime was identified at 15 cm from the incisors and successfully extracted en bloc using alligator grasping forceps. Post-extraction evaluation revealed localized mucosal excoriation without evidence of deep laceration or perforation. The patient recovered fully with no long-term sequelae. Conclusion: This case highlights the successful management of a rare and challenging esophageal foreign body. It underscores the diagnostic primacy of clinical findings over negative radiography for radiolucent objects and demonstrates the distinct advantages of rigid esophagoscopy—superior airway control, a wider operating channel, and use of robust instrumentation—for large, solid foreign bodies lodged in the proximal esophagus. In this instance, the impaction did not lead to severe complications within 24 hours, but prompt removal is essential to mitigate the risks of pressure necrosis and chemical esophagitis.

Pola Bakteri Berdasarkan Hasil Kultur dan Sensitivitas Antibiotik pada Penderita Abses Leher Dalam di Bagian THT-KL RSUP Dr. M. Djamil Padang Periode 2019-2021 Salim, Aurelia Agantha; Lestari, Yuniar; Asyari, Ade; Suharti, Netti; Ilmiawati, Cimi
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 2 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v2i1.37

Latar Belakang : Penyakit abses leher dalam merupakan perluasan peradangan dari berbagai sumber infeksi yang membentuk suatu pus di dalam ruang potensial leher dalam. Infeksi pada ruang potensial leher dalam dapat disebabkan oleh bakteri aerob, bakteri anaerob, maupun multibakterial. Terapi antibiotik empiris diberikan sebelum hasil kultur dan uji sensitivitas antibiotik didapatkan. Tatalaksana pemberian antibiotik yang tidak tepat dapat menyebabkan terjadinya resistensi antibiotik. Tujuan : Penelitian ini bertujuan untuk mengetahui pola bakteri berdasarkan hasil kultur dan sensitivitas antibiotik pada penderita abses leher dalam di Bagian THT-KL RSUP Dr. M. Djamil Padang periode 2019-2021. Metode : Jenis penelitian ini adalah deskriptif retrospektif dengan teknik total sampling dan menggunakan data sekunder. Sampel penelitian adalah pasien abses leher dalam yang terdapat hasil kultur dan uji sensitivitas antibiotik di Bagian THT-KL RSUP Dr. M. Djamil Padang periode 2019-2021 dengan total 77 pasien. Hasil : Hasil pada penelitian ini menunjukkan usia terbanyak ialah usia pertengahan (>44-59 tahun) (37,7%), jenis kelamin terbanyak ialah laki-laki (74%), lama perawatan terbanyak ialah < 7 hari (44,2%). Jenis abses leher dalam terbanyak ialah abses submandibula (42,9%), etiologi paling banyak ialah infeksi odontogenik (71,4%), terapi antibiotik empiris yang paling banyak digunakan ialah kombinasi ceftriaxone dan metronidazole (68,8%), hasil kultur terbanyak ialah bakteri Klebsiella pneumonia (18,2%), antibiotik dengan angka sensitif tertinggi ialah antibiotik amikacin (89,7%) dan meropenem (82,4%), dan angka resisten tertinggi ialah antibiotik amoxicillin (100%) dan ampicillin (93,3%). Kesimpulan : pola bakteri berdasarkan hasil kultur ialah Klebsiella pneumoniae dan uji sensitivitas antibiotik didapatkan gentamicin dengan kombinasi metronidazole yang dapat digunakan sebagai antibiotik empiris pada penderita abses leher dalam.

Analisis Nilai Peak Nasal Inspiratory Flow pada Kejadian Rinitis Alergi Faathira, Ken Rabbani; Asyari, Ade; Afdal, Afdal
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 2 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v2i1.44

Latar Belakang: Gejala hidung tersumbat sering merupakan gejala yang dominan pada rinitis alergi. Peak Nasal Inspiratory Flow (PNIF) adalah alat yang sangat bermanfaat untuk mengukur sumbatan hidung pada rinitis alergi karena terkait erat dengan tanda-tanda rinitis alergi berdasarkan pemeriksaan klinis dan berkorelasi baik dengan derajat keparahan rinitis alergi dan memiliki kelebihan yang sederhana, murah, nyaman, dan cepat. Penelitian ini bertujuan untuk menganalisis perbedaan nilai PNIF antara orang dengan rinitis alergi dan non-rinitis alergi. Metode: Penelitian ini merupakan penelitian analitik komparatif dengan menggunakan pendekatan cross sectional. Skrining rinitis alergi menggunakan kuesioner Score For Allergic Rhinitis (SFAR) kemudian dilakukan anamnesis, nasoendoskopi, dan pengukuran PNIF di poliklinik THT BKL RSUP Dr. M. Djamil Padang. Populasi adalah seluruh mahasiswa Program Studi Kedokteran Universitas Andalas yang mengidap rinitis alergi dan non-rinitis alergi dengan total sampel sebanyak 36 orang. Teknik pengambilan sampel dilakukan dengan convenience sampling. Hasil: Hasil penelitian didapatkan median nilai PNIF pada kejadian rinitis alergi sebesar 100 (50-120) L/m. Rata-rata nilai PNIF pada kejadian non-rinitis alergi sebesar 130,56 ± 24,36 L/m (Maks = 190 L/m, Min = 90 L/m). Dari hasil uji statistik Mann-Whitney didapatkan analisis beda nilai PNIF pada kejadian rinitis alergi dan non-rinitis alergi dengan nilai p < 0,001. Kesimpulan: Kesimpulannya terdapat perbedaan nilai PNIF yang signifikan antara kejadian rinitis alergi dan non-rinitis alergi.

Analysis of bile acid in saliva of patients with laryngopharyngeal reflux and non-laryngopharyngeal reflux Asyari, Ade; Utami, Refi Amalia; Yerizel, Eti; Putra, Andani Eka; Firdawati, Firdawati
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.561

ABSTRACT — Background: Laryngopharyngeal reflux (LPR) is the backflow of gastric and or duodenal fluid into the larynx, pharynx, trachea, and bronchi. The prevalence of LPR is difficult to determine due to the limited gold standard and the large variety of LPR symptoms. Damage can occur due to the decrease in pH value and also because of exposure to harmful enzymes in reflux, including bile acid. Purpose : This study was conducted to analyze bile acid levels in the saliva of LPR patient and non LPR subject. Methods: This study is an observational study with a case-control design. The study was conducted in the ORL-HNS Department of Dr. M. Djamil Hospital, Padang, West Sumatra, Indonesia. The total sample size was 44 people. We enrolled 22 healthy subjects as the control group and 22 patients suspected of having LPR. Result: LPR patients are more common in women than in men, with 12 women and 10 men. Bile acid in the LPR group means of is 25.08±7.67µM, meanwhile, in the healthy group, the mean was 18.99±8.26 µM. There is a statistically significant in the incidence of LPR with the bile acids (p = 0.015) based on t- independent test. Conclusion: Our study confirmed that bile acids in saliva play a major role in diagnosing LPR.

Gambaran kasus epistaksis di IGD RSUP Dr. M. Djamil Padang periode 2018-2022 Irfandy, Dolly; Adrial, Adrial; Sariwati, Siska; Asyari, Ade; Nofita, Eka; Anggraini, Fika Tri
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.675

Background: Epistaxis is a common case that occurs in Ear Nose Throat (ENT) Department. Epistaxis can be managed independently, but mortality and morbidity rates will increase if it occurs in children, elderly, and patient with systemic conditions. Purpose: To understand epistaxis in terms of patient age, gender, risk factor, bleeding location, treatment, and age distribution based on etiology and risk factors. Method: A descriptive retrospective study, using secondary data from medical records of patients with chief complaints of epistaxis at the emergency installation of Dr. M. Djamil General Hospital in Padang, from 2018 to 2022. Result: The study found 329 patients who came with chief complaints of epistaxis. Epistaxis mostly found at age above 45 years old. Most cases happen in males (64.1%). The most common etiology and risk factors found were hypertension (21.4%). Most frequent bleeding location found in the anterior part (80.5%). Most epistaxis patients were treated with nasal compression (26.4%). The most common causes of epistaxis in children were mechanical trauma, in young adults fractures of the maxillofacial region, and hypertension in elderly. Conclusion: Epistaxis can occur in all age groups and can occur spontaneously or accompanying a disease. The etiology and risk factors of epistaxis vary based on age groups. Epistaxis is treated according to the cause. Keywords: epistaxis, age, risk factors, treatment ABSTRAK Latar belakang: Epistaksis merupakan kasus yang sering terjadi di bagian THT. Epistaksis dapat ditangani secara mandiri, namun angka mortalitas dan morbiditas akan meningkat jika terjadi pada anak-anak, lansia, dan pasien dengan kondisi sistemik. Tujuan: Untuk mengetahui gambaran epistaksis ditinjau dari usia pasien, jenis kelamin, faktor risiko, lokasi perdarahan, penanganan, dan distribusi usia berdasarkan etiologi dan faktor risiko. Metode: Studi deskriptif retrospektif dengan menggunakan data sekunder dari rekam medis pasien dengan keluhan utama epistaksis di Instalasi Gawat Darurat RSUP Dr. M. Djamil di Padang, dari 2018-2022. Hasil: Penelitian menemukan 329 pasien yang datang dengan keluhan utama epistaksis. Epistaksis paling banyak ditemukan pada usia di atas 45 tahun. Sebagian besar kasus terjadi pada laki-laki (64,1%). Etiologi dan faktor risiko yang paling banyak ditemukan adalah hipertensi (21,4%). Lokasi perdarahan yang paling sering ditemukan di bagian anterior (80,5%). Sebagian besar pasien epistaksis ditangani dengan kompresi hidung (26,4%). Penyebab epistaksis yang paling sering ditemukan pada anak-anak adalah trauma mekanik, pada dewasa muda fraktur pada daerah maksilofasial, dan hipertensi pada lansia. Kesimpulan: Epistaksis dapat terjadi pada semua kelompok usia dan dapat terjadi secara spontan atau menyertai suatu penyakit. Etiologi dan faktor risiko epistaksis bervariasi berdasarkan kelompok usia. Penatalaksanaan epistaksis dilakukan sesuai dengan penyebabnya. Overview of epistaxis cases in emergency installation. Kata kunci: epistaksis, usia, faktor risiko, tatalaksana

EFEK SUPLEMEN KAPSUL JAHE MERAH TERHADAP REFLUX LARINGOFARINGEAL: Red Ginger and LPR Asyari, Ade; Julianda, Wahyu; Aliska, Gestina; Bachtiar, Hafni; Octavia, Tri Aryanti; Diflayzer, Diflayzer
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.690

Background: Ginger (Zingiber officinale) is a popular rhizome plant that used as a cooking and medicinal ingredient. Ginger contains many active compounds, such as phenolic and terpenes. Ginger has an anti-inflammatory effect through active ingredients, including diarylheptanoids, oleoresin, gingerol, shogaol and zingerone. Ginger powder is often used as a remedy for gastric acid reflux. In laryngopharyngeal reflux, there is a damage to the laryngopharyngeal mucosa due to irritation of gastric acid and pepsin. Purpose: To analyze the effect of red ginger powder capsule supplementation (Zyngiber officinale var. rubrum) on laryngopharyngeal reflux. Method: Non-randomized control trial study with a pretest-posttest control group design in laryngopharyngeal reflux. The patients were divided into two groups, where each group was examined for Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). The intervention group was given red ginger powder capsules and lansoprazole, while the control group was given lansoprazole only; then a month later, both groups were examined for RSI and RFS finding score. Data were analyzed statistically with a computer program and were declared significant if p<0.05. Result: There was a significant difference between RSI and RFS in the intervention group, and there was no significant difference between RSI and RFS in the control group. Meanwhile, there were significant differences in RSI and RFS between the control and intervention groups. Conclusion: There was a significant difference between the reflux symptom index and reflux finding score between the intervention group and the control group. Keywords: red ginger, Zingiber officinale var. rubrum, laryngopharyngeal reflux, reflux symptom index, reflux finding score ABSTRAK Latar belakang: Jahe (Zingiber officinale) merupakan tanaman rimpang yang populer digunakan sebagai bahan masakan dan obat. Jahe mengandung banyak senyawa aktif, seperti senyawa fenolik dan terpena. Jahe memiliki efek anti-inflamasi melalui kandungan aktifnya, antara lain diarylheptanoida, oleoresin, gingerol, shogaol dan zingeron. Bubuk jahe sering digunakan sebagai pengobatan pada kasus refluks asam lambung. Pada kelainan refluks laringofaring, terjadi kerusakan pada mukosa laringofaring akibat iritasi asam lambung dan pepsin. Tujuan: Menganalisis pengaruh suplementasi kapsul serbuk jahe merah (Zingiber officinale var. rubrum) terhadap refluks laringofaring. Metode: Menggunakan metode non-randomized control trial, dengan pendekatan pretest-posttest control group design pada refluks laringofaring. Pasien dibagi menjadi dua kelompok, dan masing-masing kelompok diperiksa indeks gejala refluks, dan skor temuan refluks. Pada kelompok intervensi diberikan kapsul serbuk jahe merah dan lansoprazole, sedangkan pada kelompok kontrol diberikan lansoprazole saja; selanjutnya, satu bulan kemudian dilakukan pemeriksaan indeks gejala refluks dan skor temuan refluks. Data dianalisis secara statistik dengan program komputer dan dinyatakan signifikan jika p<0,05. Hasil: Terdapat perbedaan yang signifikan antara indeks gejala refluks dan skor temuan refluks pada kelompok intervensi, dan tidak terdapat perbedaan yang signifikan antara indeks gejala refluks dan skor temuan refluks pada kelompok kontrol. Sementara itu, terdapat perbedaan yang signifikan pada indeks gejala refluks dan skor temuan refluks antara kelompok kontrol dan intervensi. Kesimpulan: Terdapat perbedaan yang signifikan antara indeks gejala refluks dan skor temuan refluks antara kelompok intervensi dan kelompok kontrol. Kata kunci: jahe merah, Zingiber officinale var. rubrum, refluks laringofaring, indeks gejala refluks, skor temuan refluks

Clinical and Demographic Profile of Chronic Kidney Disease Patients Undergoing Kidney Transplantation at a Tertiary Hospital in Indonesia Khairil Faiz Amir; Ade Asyari; Harun, Harnavi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1243

Background: Chronic kidney disease (CKD) is a global health problem, and kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). This study aimed to describe the clinical and demographic profile of CKD patients undergoing kidney transplantation at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: A descriptive retrospective study was conducted using medical records of CKD patients who underwent kidney transplantation between 2015 and 2023. Data on age, gender, duration of hemodialysis, donor-recipient relationship, blood pressure, blood type, crossmatch results, serum urea and creatinine levels, and etiology of CKD were collected and analyzed. Results: The study included 18 patients, all aged 19 to 59 years. The majority of patients were male (55.6%) and had undergone hemodialysis for less than 3 years (55.6%). Prehypertension and hypertension were the most prevalent blood pressure categories (44.4% each). Blood types A and O were most common (27.8% each), with consistent crossmatch results across groups. High levels of serum urea and creatinine were predominant, and hypertension was the most frequent etiology of CKD (66.7%). Conclusion: This study provides valuable insights into the characteristics of CKD patients undergoing kidney transplantation in Indonesia. The findings highlight the importance of early detection and management of CKD, particularly hypertension, to reduce the burden of ESRD and the need for transplantation.

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